-
1
-
-
84880468049
-
Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis
-
Iovino F, Orihuela CJ, Moorlag HE, Molema G, Bijlsma JJ. 2013. Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis. PLoS One 8:e68408. http://dx.doi.org/10.1371/journal.pone.0068408.
-
(2013)
PLoS One
, vol.8
, pp. e68408
-
-
Iovino, F.1
Orihuela, C.J.2
Moorlag, H.E.3
Molema, G.4
Bijlsma, J.J.5
-
2
-
-
84878969490
-
Streptococcus pneumoniae invades endothelial host cells via multiple pathways and is killed in a lysosome dependent manner
-
Gradstedt H, Iovino F, Bijlsma JJ. 2013. Streptococcus pneumoniae invades endothelial host cells via multiple pathways and is killed in a lysosome dependent manner. PLoS One 8:e65626. http://dx.doi.org/10.1371/journal.pone.0065626.
-
(2013)
PLoS One
, vol.8
, pp. e65626
-
-
Gradstedt, H.1
Iovino, F.2
Bijlsma, J.J.3
-
3
-
-
28444482410
-
Beta-arrestin 1 participates in platelet-activating factor receptormediated endocytosis of Streptococcus pneumoniae
-
Radin JN, Orihuela CJ, Murti G, Guglielmo C, Murray PJ, Tuomanen EI. 2005. Beta-arrestin 1 participates in platelet-activating factor receptormediated endocytosis of Streptococcus pneumoniae. Infect. Immun. 73: 7827-7835. http://dx.doi.org/10.1128/IAI.73.12.7827-7835.2005.
-
(2005)
Infect. Immun
, vol.73
, pp. 7827-7835
-
-
Radin, J.N.1
Orihuela, C.J.2
Murti, G.3
Guglielmo, C.4
Murray, P.J.5
Tuomanen, E.I.6
-
4
-
-
0032527622
-
Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway
-
Ring A, Weiser JN, Tuomanen EI. 1998. Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway. J. Clin. Invest. 102:347-360. http://dx.doi.org/10.1172/JCI2406.
-
(1998)
J. Clin. Invest
, vol.102
, pp. 347-360
-
-
Ring, A.1
Weiser, J.N.2
Tuomanen, E.I.3
-
5
-
-
0034664821
-
The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells
-
Zhang JR, Mostov KE, Lamm ME, Nanno M, Shimida S, Ohwaki M, Tuomanen E. 2000. The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell 102:827-837. http://dx.doi.org/10.1016/S0092-8674(00)00071-4.
-
(2000)
Cell
, vol.102
, pp. 827-837
-
-
Zhang, J.R.1
Mostov, K.E.2
Lamm, M.E.3
Nanno, M.4
Shimida, S.5
Ohwaki, M.6
Tuomanen, E.7
-
6
-
-
1842372721
-
Invasion of brain microvascular endothelial cells by group B streptococci
-
Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. 1997. Invasion of brain microvascular endothelial cells by group B streptococci. Infect. Immun. 65:5074-5081.
-
(1997)
Infect. Immun
, vol.65
, pp. 5074-5081
-
-
Nizet, V.1
Kim, K.S.2
Stins, M.3
Jonas, M.4
Chi, E.Y.5
Nguyen, D.6
Rubens, C.E.7
-
7
-
-
33750057898
-
Live cell imaging of phagosome maturation in Staphylococcus aureus infected human endothelial cells: Small colony variants are able to survive in lysosomes
-
Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M. 2006. Live cell imaging of phagosome maturation in Staphylococcus aureus infected human endothelial cells: small colony variants are able to survive in lysosomes. Med. Microbiol. Immunol. 195:185-194. http://dx.doi.org/10.1007/s00430-006-0015-0.
-
(2006)
Med. Microbiol. Immunol
, vol.195
, pp. 185-194
-
-
Schröder, A.1
Kland, R.2
Peschel, A.3
Von Eiff, C.4
Aepfelbacher, M.5
-
8
-
-
44349136839
-
Infection of cultured human endothelial cells by Legionella pneumophila
-
Chiaraviglio L, Brown DA, Kirby JE. 2008. Infection of cultured human endothelial cells by Legionella pneumophila. PLoS One 3:e2012. http://dx.doi.org/10.1371/journal.pone.0002012.
-
(2008)
PLoS One
, vol.3
, pp. e2012
-
-
Chiaraviglio, L.1
Brown, D.A.2
Kirby, J.E.3
-
9
-
-
78650090605
-
Ubiquitin makes its mark on immune regulation
-
Malynn BA, Ma A. 2010. Ubiquitin makes its mark on immune regulation. Immunity 33:843-852. http://dx.doi.org/10.1016/j.immuni.2010.12.007.
-
(2010)
Immunity
, vol.33
, pp. 843-852
-
-
Malynn, B.A.1
Ma, A.2
-
10
-
-
59349088768
-
Manipulation of the ubiquitinproteasome pathway by small DNA tumor viruses
-
Blanchette P, Branton PE. 2009. Manipulation of the ubiquitinproteasome pathway by small DNA tumor viruses. Virology 384:317-323. http://dx.doi.org/10.1016/j.virol.2008.10.005.
-
(2009)
Virology
, vol.384
, pp. 317-323
-
-
Blanchette, P.1
Branton, P.E.2
-
11
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund K, Dikic I. 2005. Ubiquitylation and cell signaling. EMBO J. 24:3353-3359. http://dx.doi.org/10.1038/sj.emboj.7600808.
-
(2005)
EMBO J
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
12
-
-
0032535483
-
The ubiquitin-proteasome pathway: On protein death and cell life
-
Ciechanover A. 1998. The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J. 17:7151-7160. http://dx.doi.org/10.1093/emboj/17.24.7151.
-
(1998)
EMBO J
, vol.17
, pp. 7151-7160
-
-
Ciechanover, A.1
-
14
-
-
1542373897
-
Distinct monoubiquitin signals in receptor endocytosis
-
Haglund K, Di Fiore PP, Dikic I. 2003. Distinct monoubiquitin signals in receptor endocytosis. Trends Biochem. Sci. 28:598-603. http://dx.doi.org/10.1016/j.tibs.2003.09.005.
-
(2003)
Trends Biochem. Sci
, vol.28
, pp. 598-603
-
-
Haglund, K.1
Di Fiore, P.P.2
Dikic, I.3
-
15
-
-
38449099679
-
Role of proteasomes in disease
-
Dahlmann B. 2007. Role of proteasomes in disease. BMC Biochem. 8(Suppl 1):S3. http://dx.doi.org/10.1186/1471-2091-8-S1-S3.
-
(2007)
BMC Biochem
, vol.8
, pp. S3
-
-
Dahlmann, B.1
-
16
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund K, Dikic I. 2005. Ubiquitylation and cell signaling. EMBO J. 24:3353-3359. http://dx.doi.org/10.1038/sj.emboj.7600808.
-
(2005)
EMBO J
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
17
-
-
78650090605
-
Ubiquitin makes its mark on immune regulation
-
Malynn BA, Ma A. 2010. Ubiquitin makes its mark on immune regulation. Immunity 33:843-852. http://dx.doi.org/10.1016/j.immuni.2010.12.007.
-
(2010)
Immunity
, vol.33
, pp. 843-852
-
-
Malynn, B.A.1
Ma, A.2
-
18
-
-
33947714944
-
Bacterial interference of ubiquitination and deubiquitination
-
Rytkönen A, Holden DW. 2007. Bacterial interference of ubiquitination and deubiquitination. Cell Host Microbe 1:13-22. http://dx.doi.org/10.1016/j.chom.2007.02.003.
-
(2007)
Cell Host Microbe
, vol.1
, pp. 13-22
-
-
Rytkönen, A.1
Holden, D.W.2
-
19
-
-
0035830911
-
The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-secretase
-
Steinhilb ML, Turner RS, Gaut JR. 2001. The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-secretase. J. Biol. Chem. 276:4476-4484. http://dx.doi.org/10.1074/jbc.M008793200.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 4476-4484
-
-
Steinhilb, M.L.1
Turner, R.S.2
Gaut, J.R.3
-
20
-
-
0344413859
-
Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation
-
Kubori T, Galán JE. 2003. Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation. Cell 115:333-342. http://dx.doi.org/10.1016/S0092-8674(03)00849-3.
-
(2003)
Cell
, vol.115
, pp. 333-342
-
-
Kubori, T.1
Galán, J.E.2
-
21
-
-
33751285781
-
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
-
Chen D, Cui QC, Yang H, Dou QP. 2006. Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity. Cancer Res. 66:10425-10433. http://dx.doi.org/10.1158/0008-5472.CAN-06-2126.
-
(2006)
Cancer Res
, vol.66
, pp. 10425-10433
-
-
Chen, D.1
Cui, Q.C.2
Yang, H.3
Dou, Q.P.4
-
22
-
-
33845304732
-
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients
-
Wickström M, Danielsson K, Rickardson L, Gullbo J, Nygren P, Isaksson A, Larsson R, Lövborg H. 2007. Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients. Biochem. Pharmacol. 73:25-33. http://dx.doi.org/10.1016/j.bcp.2006.08.016.
-
(2007)
Biochem. Pharmacol
, vol.73
, pp. 25-33
-
-
Wickström, M.1
Danielsson, K.2
Rickardson, L.3
Gullbo, J.4
Nygren, P.5
Isaksson, A.6
Larsson, R.7
Lövborg, H.8
-
23
-
-
33644549964
-
Inhibition of proteasome activity, nuclear factor-kappaB translocation and cell survival by the antialcoholism drug disulfiram
-
Lövborg H, Oberg F, Rickardson L, Gullbo J, Nygren P, Larsson R. 2006. Inhibition of proteasome activity, nuclear factor-kappaB translocation and cell survival by the antialcoholism drug disulfiram. Int. J. Cancer 118:1577-1580. http://dx.doi.org/10.1002/ijc.21534.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1577-1580
-
-
Lövborg, H.1
Oberg, F.2
Rickardson, L.3
Gullbo, J.4
Nygren, P.5
Larsson, R.6
-
24
-
-
35148886143
-
Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics
-
Yang Y, Kitagaki J, Dai RM, Tsai YC, Lorick KL, Ludwig RL, Pierre SA, Jensen JP, Davydov IV, Oberoi P, Li CC, Kenten JH, Beutler JA, Vousden KH, Weissman AM. 2007. Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. Cancer Res. 67:9472-9481. http://dx.doi.org/10.1158/0008-5472.CAN-07-0568.
-
(2007)
Cancer Res
, vol.67
, pp. 9472-9481
-
-
Yang, Y.1
Kitagaki, J.2
Dai, R.M.3
Tsai, Y.C.4
Lorick, K.L.5
Ludwig, R.L.6
Pierre, S.A.7
Jensen, J.P.8
Davydov, I.V.9
Oberoi, P.10
Li, C.C.11
Kenten, J.H.12
Beutler, J.A.13
Vousden, K.H.14
Weissman, A.M.15
-
25
-
-
40949162838
-
The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease
-
Kadioglu A, Weiser JN, Paton JC, Andrew PW. 2008. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat. Rev. Microbiol. 6:288-301. http://dx.doi.org/10.1038/nrmicro1871.
-
(2008)
Nat. Rev. Microbiol
, vol.6
, pp. 288-301
-
-
Kadioglu, A.1
Weiser, J.N.2
Paton, J.C.3
Andrew, P.W.4
-
26
-
-
23344444876
-
Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells
-
Hammerschmidt S, Wolff S, Hocke A, Rosseau S, Müller E, Rohde M. 2005. Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells. Infect. Immun. 73:4653-4667. http://dx.doi.org/10.1128/IAI.73.8.4653-4667.2005.
-
(2005)
Infect. Immun
, vol.73
, pp. 4653-4667
-
-
Hammerschmidt, S.1
Wolff, S.2
Hocke, A.3
Rosseau, S.4
Müller, E.5
Rohde, M.6
-
27
-
-
20244373759
-
PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation
-
Pracht D, Elm C, Gerber J, Bergmann S, Rohde M, Seiler M, Kim KS, Jenkinson HF, Nau R, Hammerschmidt S. 2005. PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect. Immun. 73:2680-2689. http://dx.doi.org/10.1128/IAI.73.5.2680-2689.2005.
-
(2005)
Infect. Immun
, vol.73
, pp. 2680-2689
-
-
Pracht, D.1
Elm, C.2
Gerber, J.3
Bergmann, S.4
Rohde, M.5
Seiler, M.6
Kim, K.S.7
Jenkinson, H.F.8
Nau, R.9
Hammerschmidt, S.10
-
28
-
-
11844279803
-
Ubiquitination of intracellular bacteria: A new bacteria-sensing system?
-
Veiga E, Cossart P. 2005. Ubiquitination of intracellular bacteria: a new bacteria-sensing system? Trends Cell Biol. 15:2-5. http://dx.doi.org/10.1016/j.tcb.2004.11.005.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 2-5
-
-
Veiga, E.1
Cossart, P.2
-
29
-
-
67650079165
-
Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium
-
Coureuil M, Mikaty G, Miller F, Lécuyer H, Bernard C, Bourdoulous S, Duménil G, Mège RM, Weksler BB, Romero IA, Couraud PO, Nassif X. 2009. Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science 325:83-87. http://dx.doi.org/10.1126/science.1173196.
-
(2009)
Science
, vol.325
, pp. 83-87
-
-
Coureuil, M.1
Mikaty, G.2
Miller, F.3
Lécuyer, H.4
Bernard, C.5
Bourdoulous, S.6
Duménil, G.7
Mège, R.M.8
Weksler, B.B.9
Romero, I.A.10
Couraud, P.O.11
Nassif, X.12
-
30
-
-
53149104367
-
Pneumolysin: A doubleedged sword during the host-pathogen interaction
-
Marriott HM, Mitchell TJ, Dockrell DH. 2008. Pneumolysin: a doubleedged sword during the host-pathogen interaction. Curr. Mol. Med. 8:497-509. http://dx.doi.org/10.2174/156652408785747924.
-
(2008)
Curr. Mol. Med
, vol.8
, pp. 497-509
-
-
Marriott, H.M.1
Mitchell, T.J.2
Dockrell, D.H.3
-
31
-
-
55849124698
-
The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junction cleavage
-
Attali C, Durmort C, Vernet T, Di Guilmi AM. 2008. The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junction cleavage. Infect. Immun. 76:5350-5356. http://dx.doi.org/10.1128/IAI.00184-08.
-
(2008)
Infect. Immun
, vol.76
, pp. 5350-5356
-
-
Attali, C.1
Durmort, C.2
Vernet, T.3
Di Guilmi, A.M.4
-
32
-
-
2342464290
-
Recognition of bacteria in the cytosol of Mammalian cells by the ubiquitin system
-
Perrin AJ, Jiang X, Birmingham CL, So NS, Brumell JH. 2004. Recognition of bacteria in the cytosol of Mammalian cells by the ubiquitin system. Curr. Biol. 14:806-811. http://dx.doi.org/10.1016/j.cub.2004.09.022.
-
(2004)
Curr. Biol
, vol.14
, pp. 806-811
-
-
Perrin, A.J.1
Jiang, X.2
Birmingham, C.L.3
So, N.S.4
Brumell, J.H.5
-
33
-
-
84892678766
-
Bacteria-autophagy interplay: A battle for survival
-
Huang J, Brumell JH. 2014. Bacteria-autophagy interplay: a battle for survival. Nat. Rev. Microbiol. 12:101-114. http://dx.doi.org/10.1038/nrmicro3160.
-
(2014)
Nat. Rev. Microbiol
, vol.12
, pp. 101-114
-
-
Huang, J.1
Brumell, J.H.2
-
34
-
-
0033054154
-
The ubiquitin-proteasome system and endocytosis
-
Strous GJ, Govers R. 1999. The ubiquitin-proteasome system and endocytosis. J. Cell Sci. 112:1417-1423.
-
(1999)
J. Cell Sci
, vol.112
, pp. 1417-1423
-
-
Strous, G.J.1
Govers, R.2
-
35
-
-
84908260544
-
-
12 January, Dutch Government, Amsterdam, The Netherlands. (In Dutch.)
-
Dutch Government. 12 January 1997. Wet op de dierproeven. Dutch Government, Amsterdam, The Netherlands. (In Dutch.)
-
(1997)
Wet op de dierproeven
-
-
-
36
-
-
84908261647
-
-
31 May, Dutch Government, Amsterdam, The Netherlands. (In Dutch.)
-
Dutch Government. 31 May 1985. Dierproevenbesluit. Dutch Government, Amsterdam, The Netherlands. (In Dutch.)
-
(1985)
Dierproevenbesluit
-
-
-
37
-
-
67651007158
-
Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models
-
Orihuela CJ, Mahdavi J, Thornton J, Mann B, Wooldridge KG, Abouseada N, Oldfield NJ, Self T, Ala’Aldeen DA, Tuomanen EI. 2009. Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models. J. Clin. Invest. 119:163-1646. http://dx.doi.org/10.1172/JCI36759.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 163-1646
-
-
Orihuela, C.J.1
Mahdavi, J.2
Thornton, J.3
Mann, B.4
Wooldridge, K.G.5
Abouseada, N.6
Oldfield, N.J.7
Self, T.8
Ala’aldeen, D.A.9
Tuomanen, E.I.10
-
38
-
-
0035919670
-
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae
-
Tettelin H, Nelson KE, Paulsen IT, Eisen JA, Read TD, Peterson S, Heidelberg J, DeBoy RT, Haft DH, Dodson RJ, Durkin AS, Gwinn M, Kolonay JF, Nelson WC, Peterson JD, Umayam LA, White O, Salzberg SL, Lewis MR, Radune D, Holtzapple E, Khouri H, Wolf AM, Utterback TR, Hansen CL, McDonald LA, Feldblyum TV, Angiuoli S, Dickinson T, Hickey EK, Holt IE, Loftus BJ, Yang F, Smith HO, Venter JC, Dougherty BA, Morrison DA, Hollingshead SK, Fraser CM. 2001. Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science 293: 498-506. http://dx.doi.org/10.1126/science.1061217.
-
(2001)
Science
, vol.293
, pp. 498-506
-
-
Tettelin, H.1
Nelson, K.E.2
Paulsen, I.T.3
Eisen, J.A.4
Read, T.D.5
Peterson, S.6
Heidelberg, J.7
Deboy, R.T.8
Haft, D.H.9
Dodson, R.J.10
Durkin, A.S.11
Gwinn, M.12
Kolonay, J.F.13
Nelson, W.C.14
Peterson, J.D.15
Umayam, L.A.16
White, O.17
Salzberg, S.L.18
Lewis, M.R.19
Radune, D.20
Holtzapple, E.21
Khouri, H.22
Wolf, A.M.23
Utterback, T.R.24
Hansen, C.L.25
McDonald, L.A.26
Feldblyum, T.V.27
Angiuoli, S.28
Dickinson, T.29
Hickey, E.K.30
Holt, I.E.31
Loftus, B.J.32
Yang, F.33
Smith, H.O.34
Venter, J.C.35
Dougherty, B.A.36
Morrison, D.A.37
Hollingshead, S.K.38
Fraser, C.M.39
more..
-
39
-
-
77955288147
-
Carbonic anhydrase is essential for Streptococcus pneumoniae growth in environmental ambient air
-
Burghout P, Cron LE, Gradstedt H, Quintero B, Simonetti E, Bijlsma JJ, Bootsma HJ, Hermans PW. 2010. Carbonic anhydrase is essential for Streptococcus pneumoniae growth in environmental ambient air. J. Bacteriol. 192:4054-4062. http://dx.doi.org/10.1128/JB.00151-10.
-
(2010)
J. Bacteriol
, vol.192
, pp. 4054-4062
-
-
Burghout, P.1
Cron, L.E.2
Gradstedt, H.3
Quintero, B.4
Simonetti, E.5
Bijlsma, J.J.6
Bootsma, H.J.7
Hermans, P.W.8
-
40
-
-
0035154799
-
Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells
-
Stins MF, Badger J, Sik Kim K. 2001. Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells. Microb. Pathog. 30:19-28. http://dx.doi.org/10.1006/mpat.2000.0406.
-
(2001)
Microb. Pathog
, vol.30
, pp. 19-28
-
-
Stins, M.F.1
Badger, J.2
Sik Kim, K.3
-
41
-
-
72449163929
-
Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro—a quantitative study
-
Asgeirsdóttir SA, Talman EG, de Graaf IA, Kamps JA, Satchell SC, Mathieson PW, Ruiters MH, Molema G. 2010. Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro—a quantitative study. J. Control. Release 141:241-251. http://dx.doi.org/10.1016/j.jconrel.2009.09.008.
-
(2010)
J. Control. Release
, vol.141
, pp. 241-251
-
-
Asgeirsdóttir, S.A.1
Talman, E.G.2
De Graaf, I.A.3
Kamps, J.A.4
Satchell, S.C.5
Mathieson, P.W.6
Ruiters, M.H.7
Molema, G.8
|