PUL21a-Cyclin A2 Interaction is Required to Protect Human Cytomegalovirus-Infected Cells from the Deleterious Consequences of Mitotic Entry

PLoS Pathogens

Volumn 10, Issue 11, 2014, Pages

  Eifler, Martin ^a,c   Uecker, Ralf ^a   Weisbach, Henry ^a   Bogdanow, Boris ^a,d   Richter, Ellen ^a,e   König, Lydia ^a   Vetter, Barbara ^a   Lenac Rovis, Tihana ^b   Jonjic, Stipan ^b   Neitzel, Heidemarie ^a   Hagemeier, Christian ^a   Wiebusch, Lüder ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF RIJEKA   (Croatia)

^c TIB MOLBIOL GmbH   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ANAPHASE PROMOTING COMPLEX SUBUNIT 5; APC PROTEIN; CELL DNA; CENTROMERE PROTEIN A; CYCLIN A2; CYCLIN B1; CYCLIN C; CYCLIN D1; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYTOMEGALOVIRUS ANTIGEN PP150; CYTOMEGALOVIRUS ANTIGEN PP28; CYTOMEGALOVIRUS ANTIGEN PP65; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE H3; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN LIGHT CHAIN; ISOPROPYL THIOGALACTOSIDE; LAMIN A; LAMIN C; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; PUL21A PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS ANTIGEN; CCNA2 PROTEIN, HUMAN; IE2 PROTEIN, CYTOMEGALOVIRUS; IMMEDIATE EARLY PROTEIN; PROTEASOME; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BRDU ASSAY; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL PROTECTION; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME CONDENSATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DNA BINDING MOTIF; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENETIC TRANSFECTION; GIEMSA STAIN; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; MAP KINASE ASSAY; METAPHASE; MITOSIS; MOUSE; MUTAGENESIS; NONHUMAN; POINT MUTATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RECOMBINANT PLASMID; RIBONUCLEASE PROTECTION ASSAY; VIRUS REPLICATION; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL LINE; CYTOMEGALOVIRUS; DNA REPLICATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN ANALYSIS; UPREGULATION;

HUMAN HERPESVIRUS 5;

CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE; CYCLIN A2; CYTOMEGALOVIRUS; DNA REPLICATION; GENE EXPRESSION REGULATION; HUMANS; IMMEDIATE-EARLY PROTEINS; MITOSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; TRANS-ACTIVATORS; UP-REGULATION; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 85047970982     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004514     Document Type: Article

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