Cell cycle dysregulation by human cytomegalovirus: Influence of the cell cycle phase at the time of infection and effects on cyclin transcription

Journal of Virology

Volumn 72, Issue 5, 1998, Pages 3729-3741

  Salvant, Bryan S ^a   Fortunato, Elizabeth A ^a   Spector, Deborah H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN B; CYCLIN E;

ARTICLE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CYTOMEGALOVIRUS; CYTOPATHOGENIC EFFECT; DNA SYNTHESIS; GROWTH REGULATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS EXPRESSION;

EID: 0031968822     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.5.3729-3741.1998     Document Type: Article

References (40)

1. AbuBakar, S., W. W. Au, M. S. Legator, and T. Albrecht. 1988. Induction of chromosome aberrations and mitotic arrest by cytomegalovirus in human cells. Environ. Mol. Mutagen. 12:409-420.
2. Albrecht, T., I. Boldogh, M. Fons, C. H. Lee, S. AbuBakar, J. M. Russell, and W. W. Au. 1989. Cell-activation responses to cytomegalovirus infection: relationship to the phasing of CMV replication and to the induction of cellular damage. Subcell. Biochem. 15:157-202.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1994. Current protocols in molecular biology, vol. 1. John Wiley & Sons, Inc., New York, N.Y.
4. Beijersbergen, R. L., and R. Bernards. 1996. Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins. Biochim. Biophys. Acta 1287:103-120.
5. Boldogh, I., S. AbuBakar, C. Z. Deng, and T. Albrecht. 1991. Transcriptional activation of cellular oncogenes fos, jun, and myc by human cytomegalovirus. J. Virol. 65:1568-1571.
6. Bresnahan, W. A., I. Boldogh, P. Chi, E. A. Thompson, and T. Albrecht. 1997. Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication. Virology 231:239-247.
7. Bresnahan, W. A., I. Boldogh, E. A. Thompson, and T. Albrecht. 1996. Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1. Virology 224:150-160.
8. Bresnahan, W. A., I. Boldogh, E. A. Thompson, and T. Albrecht. 1997. Human cytomegalovirus infection results in altered cdk2 subcellular localization. J. Gen. Virol. 78:1993-1997.
9. Britt, W., and C. Alford. 1996. Cytomegalovirus, p. 2493-2523. In B. N. Fields et al., Fields Virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, Pa.
10. + T cells. J. Gen. Virol. 76:681-690.
11. Cranmer, L. D., C. Clark, and D. H. Spector. 1994. Cloning, characterization, and expression of the murine cytomegalovirus homologue of the human cytomegalovirus 28-kDa matrix phosphoprotein (UL99). Virology 205:417-429.
12. Darzynkiewicz, Z., S. Bruno, G. D. Bino, W. Gorczyca, M. A. Hotz, P. Lassota, and F. Traganos. 1992. Features of apoptotic cells measured by flow cytometry. Cytometry 13:795-808.
13. 1/S-regulatory genes. Mol. Cell. Biol. 15:4215-4224.
14. DeMarchi, J. M. 1983. Correlation between stimulation of host cell DNA synthesis by human cytomegalovirus and lack of expression of a subset of early virus gene. Virology 129:274-286.
15. DeMarchi, J. M., and A. S. Kaplan. 1976. Replication of human cytomegalovirus DNA: lack of dependence on cell DNA synthesis. J. Virol. 18:1063-1070.
16. DeMarchi, J. M., and A. S. Kaplan. 1977. Physiological state of human embryonic lung cells affects their response to human cytomegalovirus. J. Virol. 23:126-132.
17. Desdouets, C., G. Matesic, C. A. Molina, N. S. Foulkes, P. Sassone-Corsi, C. Brechot, and J. Sobszak-Thepot. 1995. Cell cycle regulation of cyclin A gene expression by the cyclic AMP transcription factors CREB and CREM. Mol. Cell. Biol. 15:3301-3309.
18. 1/S transition. J. Virol. 71:1629-1634.
19. Enoch, T., and P. Nurse. 1991. Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell 65: 921-923.
20. Geng, Y., E. N. Eaton, M. Picon, J. M. Roberts, A. S. Lundberg, A. Gifford, C. Sardet, and R. A. Weinberg. 1996. Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12:1173-1180.
21. Hartwell, L. H., and T. A. Weinert. 1989. Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634.
22. Henglein, B., X. Chenivesse, J. Wang, D. Eick, and C. Brechot. 1994. Structure and cell cycle-regulated transcription of the human cyclin A gene. Proc. Natl. Acad. Sci. USA 91:5490-5494.
23. Jault, F. M., J.-M. Jault, F. Ruchti, E. A. Fortunato, C. Clark, J. Corbeil, D. D. Richman, and D. H. Spector. 1995. Cytomegalovirus infection induces high levels of cyclins, phosphorylated RB, and p53, leading to cell cycle arrest. J. Virol. 69:6697-6704.
24. King, R. W., P. K. Jackson, and M. W. Kirschner. 1994. Mitosis in transition. Cell 79:563-571.
25. Klucher, K. M., M. Sommer, J. T. Kadonaga, and D. H. Spector. 1993. In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins. Mol. Cell. Biol. 13:1238-1250.
26. 1 to S. J. Virol. 70:8850-8857.
27. McElroy, A., and D. H. Spector. 1997. Unpublished data.
28. Mocarski, E. S. 1996. Cytomegaloviruses and their replication, p. 2447-2492. In B. N. Fields et al., Fields Virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, Pa.
29. Muganda, P., O. Mendoza, J. Hernandez, and Q. Qian. 1994. Human cytomegalovirus elevates levels of the cellular protein p53 in infected fibroblasts. J. Virol. 68:8028-8034.
30. Ohtani, K., J. Degregori, and J. R. Nevins. 1995. Regulation of the cyclin E promoter by transcription factor E2F1. Proc. Natl. Acad. Sci. USA 92: 12146-12150.
31. 1-to-S phase transition. Mol. Cell. Biol. 15:2612-2624.
32. Pines, J. 1993. Cyclins and cyclin-dependent kinases: take your partners. Trends Biochem. Sci. 18:195-197.
33. Pines, J. 1995. Cyclins and cyclin-dependent kinases: theme and variations. Adv. Cancer Res. 66:181-212.
34. Poma, E. E., T. F. Kowalik, L. Zhu, J. H. Sinclair, and E.-S. Huang. 1996. The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter. J. Virol. 70:7867-7877.
35. 1→S transition of mammalian cells. J. Cell. Biochem. 54:379-386.
36. Schulze, A., K. Zerfass, D. Spitkovsky, S. Middendorp, J. Berges, K. Helin, P. Jansen-Durr, and B. Henglein. 1995. Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site. Proc. Natl. Acad. Sci. USA 92:11264-11268.
37. 1 cyclins. Cell 73:1059-1065.
38. Speir, E., R. Modali, E.-S. Huang, M. B. Leon, F. Shawl, T. Finkel, and S. E. Epstein. 1994. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 265:391-394.
39. Telford, W. G., L. E. King, and P. J. Fraker. 1992. Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry 13:137-143.
40. Zwicker, J., F. C. Lucibello, L. A. Wolfraim, C. Gross, M. Truss, K. Engeland, and R. Muller. 1995. Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression. EMBO J. 14:4514-4522.