Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Stevens, Deanna ^a   Gassmann, Reto ^a   Oegema, Karen ^a   Desai, Arshad ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B; KINESIN; PROTEASOME INHIBITOR;

ANAPHASE; ARTICLE; CELL CYCLE ARREST; CELL DIVISION; CENTRIOLE; CENTROMERE; CHROMOSOME SEGREGATION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; KARYOTYPING; METAPHASE; MICROTUBULE; MITOSIS SPINDLE; PHENOTYPE; PROTEIN EXPRESSION; SISTER CHROMATID; CHROMATID;

CHROMATIDS; HELA CELLS; HUMANS; METAPHASE;

EID: 79960988207     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022969     Document Type: Article

References (41)

1. Nasmyth K, Haering CH, (2009) Cohesin: its role and mechanisms. Ann Rev Genet 43: 525-558.
2. Sherwood R, Takahashi TS, Jallepalli PV, (2010) Sister acts: coordinating DNA replication and cohesion establishment. Genes & Dev 24: 2723-2731.
3. Waizenegger IC, Hauf S, Meinke A, Peters JM, (2000) Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell 103: 399-410.
4. Losada A, Hirano M, Hirano T, (2002) Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes & Dev 16: 3004-3016.
5. Sumara I, Vorlaufer E, Stukenberg PT, Kelm O, Redemann N, et al. (2002) The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell 9: 515-525.
6. Gandhi R, Gillespie PJ, Hirano T, (2006) Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Curr Biol 16: 2406-2417.
7. Kueng S, Hegemann B, Peters BH, Lipp JJ, Schleiffer A, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127: 955-967.
8. Uhlmann F, Lottspeich F, Nasmyth K, (1999) Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature 400: 37-42.
9. Hauf S, Waizenegger IC, Peters JM, (2001) Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science 293: 1320-1323.
10. Zachariae CH, Nasmyth K, (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes & Dev 13: 2039-2058.
11. Stemmann O, Zou H, Gerber SA, Gygi SP, Kirschner MW, (2001) Dual inhibition of sister chromatid separation at metaphase. Cell 107: 715-726.
12. Jallepalli PV, Waizenegger IC, Bunz F, Langer S, Speicher MR, et al. (2001) Securin is required for chromosomal stability in human cells. Cell 105: 445-457.
13. McGuinness BE, Hirota T, Kudo NR, Peters JM, Nasmyth K, (2005) Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol 3 (3): e86.
14. Wirth KG, Wutz G, Kudo NR, Desdouets C, Zetterberg A, et al. (2006) Separase: a univeral trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol 172: 847-860.
15. Daum JR, Wren JD, Daniel JJ, Sivakumar S, McAvoy JN, et al. (2009) Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis. Curr Biol 19: 1467-1472.
16. Gassmann R, Holland AJ, Varma D, Wan X, Civril F, et al. (2010) Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes & Dev 24: 957-971.
17. Holloway SL, Gotzer M, King MW, Murray AW, (1993) Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73: 1393-1402.
18. Gallant P, Nigg EA, (1992) Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. J Cell Biol 117: 213-224.
19. Qian X, McDonald AI, Zhou HJ, Ashcraft LW, Yao B, et al. (2008) US Patent no. 0255182 A1.
20. Wood KW, Lad L, Luo L, Qian X, Knight SD, et al. (2010) Antitumor activity of an allosteric inhibitor of centromere-associated protein-E. Proc Natl Acad Sci USA 107: 5839-5844.
21. Huang HC, Shi J, Orth JD, Mitchison TJ, (2009) Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 16: 347-358.
22. Hardwick KG, Shah JV, (2010) Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset. F1000 Biol Rep 2: 55.
23. Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musachio A, (2010) Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol 190: 73-87.
24. Bloom K, Yeh E, (2010) Tension management at the kinetochore. Curr Biol 20: R1040-1048.
25. Hauf S, Roitinger E, Koch B, Dittrich CM, Mechtler K, et al. (2005) Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3: e69.
26. Shintomi K, Hirano T, (2009) Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1. Genes & Dev 23: 2224-2236.
27. Rieder CL, Cole RW, Khodjakov A, Sluder G, (1995) The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced at unattached kinetochores. J Cell Biol 130: 941-948.
28. Matos I, Pereira AJ, Lince-Faria M, Cameron LA, Salmon ED, et al. (2009) Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores. J Cell Biol 186: 11-26.
29. Nakajima M, Kumada K, Hatakeyama K, Noda T, Peters JM, et al. (2007) The complete removal of cohesin from chromosome arms depends on separase. J Cell Sci 120: 4188-4196.
30. Tsou MF, Wang WJ, George KA, Uryu K, Sterns T, et al. (2009) Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells. Dev Cell 17: 344-354.
31. Daum JR, Potapova TA, Sivakumar S, Daniel JJ, Flynn JN, et al. (2011) Cohesion fatigue induces chromatid separation in cells delayed at metaphase. Curr Biol 21: 1018-1024.
32. Cho JH, Chang CJ, Chen CY, Tang TK, (2006) Depletion of CPAP by RNAi disrupts centrosome integrity and induces multipolar spindles. Biochem Biophys Res Commun 339: 742-747.
33. Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachuary MV, et al. (2007) The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Dev Cell 13: 29-42.
34. Thein KH, Kleylein-Sohn J, Nigg EA, Gruneberg U, (2007) Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol 178: 345-354.
35. Woolner S, O'Brien LL, Wiese C, Bement WM, (2008) Myosin-10 and actin filaments are essential for mitotic spindle function. J Cell Biol 182: 77-88.
36. Yang S, Liu X, Yin Y, Fukuda MN, Zhou J, (2008) Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis. FASEB J 22: 1960-1972.
37. Wu G, Lin YT, Wei R, Chen Y, Shan Z, et al. (2008) Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells. Mol Cell Biol 28: 3652-3662.
38. Fang L, Seki A, Fan G, (2009) SKAP associates with kinetochores and promotes the metaphase-to-anaphase transition. Cell Cycle 8: 2819-2827.
39. Mattiuzzo M, Vargiu G, Totta P, Fiore M, Ciferri C, et al. (2011) Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1. PLoS One 6: e16307.
40. Tighe A, Johnson VL, Taylor SS, (2004) Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability. J Cell Sci 117: 6339-6353.
41. Shah J, Botvinick E, Bonday Z, Furnari F, Berns M, et al. (2004) Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Curr Biol 14: 942-952.