메뉴 건너뛰기




Volumn 154, Issue 4, 2013, Pages 363-372

Inhibition of DNA binding of MCM2-7 complex by phosphorylation with cyclin-dependent kinases

Author keywords

Chemical Modification < Enzyme; DNA Binding < Protein; Phosphorylation < Protein; Protein Kinases CDKs < Signal Transduction; Replication < DNA

Indexed keywords

ALANINE; BINDING PROTEIN; CDC7 KINASE; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; MINICHROMOSOME MAINTENANCE PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7; PROTEIN SERINE THREONINE KINASE; RECQ HELICASE; RECQ L4; REPLICATION FACTOR A; REPLICATION FACTOR A2; SERINE; THREONINE; TRESLIN PROTEIN; UNCLASSIFIED DRUG;

EID: 84885345040     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvt062     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • Bell, S.P. and Dutta, A. (2002) DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71, 333-374
    • (2002) Annu. Rev. Biochem , vol.71 , pp. 333-374
    • Bell, S.P.1    Dutta, A.2
  • 2
    • 1542405310 scopus 로고    scopus 로고
    • Eukaryotic MCM proteins: Beyond replication initiation
    • Forsburg, S.L. (2004) Eukaryotic MCM proteins: beyond replication initiation. Microbiol. Mol. Biol. Rev. 68, 109-131
    • (2004) Microbiol. Mol. Biol. Rev , vol.68 , pp. 109-131
    • Forsburg, S.L.1
  • 3
    • 77953632048 scopus 로고    scopus 로고
    • Eukaryotic chromosome DNA replication: Where, when, and how? Annu
    • Masai, H., Matsumoto, S., You, Z., Yoshizawa-Sugata, N., and Oda, H. (2010) Eukaryotic chromosome DNA replication: where, when, and how? Annu. Rev. Biochem. 79, 89-130
    • (2010) Rev. Biochem , vol.79 , pp. 89-130
    • Masai, H.1    Matsumoto, S.2    You, Z.3    Yoshizawa-Sugata, N.4    Oda, H.5
  • 4
    • 80053329001 scopus 로고    scopus 로고
    • Initiation of chromosomal DNA replication in eukaryotic cells; Contribution of yeast genetics to the elucidation
    • Araki, H. (2011) Initiation of chromosomal DNA replication in eukaryotic cells; contribution of yeast genetics to the elucidation. Genes Genet. Syst. 86, 141-149
    • (2011) Genes Genet. Syst , vol.86 , pp. 141-149
    • Araki, H.1
  • 5
    • 77953954908 scopus 로고    scopus 로고
    • How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?
    • Labib, K. (2010) How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? Genes Dev 24, 1208-1219
    • (2010) Genes Dev , vol.24 , pp. 1208-1219
    • Labib, K.1
  • 6
    • 73849129578 scopus 로고    scopus 로고
    • The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
    • Sheu, Y.-J. and Stillman, B. (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463, 113-117
    • (2010) Nature , vol.463 , pp. 113-117
    • Sheu, Y.-J.1    Stillman, B.2
  • 8
    • 33846330909 scopus 로고    scopus 로고
    • CDK-dependent phosphorylation of Sld2 and Sld3 initiate DNA replication in budding yeast
    • Tanaka, S., Umemori, T., Hirai, K., Muramatsu, S., Kamimura, Y., and Akaki, H. (2007) CDK-dependent phosphorylation of Sld2 and Sld3 initiate DNA replication in budding yeast. Nature 445, 328-332
    • (2007) Nature , vol.445 , pp. 328-332
    • Tanaka, S.1    Umemori, T.2    Hirai, K.3    Muramatsu, S.4    Kamimura, Y.5    Akaki, H.6
  • 9
    • 33846328709 scopus 로고    scopus 로고
    • Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
    • Zegerman, P. and Diffley, J.F. (2007) Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 445, 281-285
    • (2007) Nature , vol.445 , pp. 281-285
    • Zegerman, P.1    Diffley, J.F.2
  • 10
    • 4544221279 scopus 로고    scopus 로고
    • Regulation of early events in chromosome replication
    • Diffley, J.F.X. (2004) Regulation of early events in chromosome replication. Curr. Biol. 14, R778-R786
    • (2004) Curr. Biol , vol.14
    • Diffley, J.F.X.1
  • 11
    • 0035998262 scopus 로고    scopus 로고
    • Control of DNA replication licensing in a cell cycle
    • Nishitani, H. and Lygerou, Z. (2002) Control of DNA replication licensing in a cell cycle. Genes Cells 7, 523-534
    • (2002) Genes Cells , vol.7 , pp. 523-534
    • Nishitani, H.1    Lygerou, Z.2
  • 12
    • 0035963372 scopus 로고    scopus 로고
    • Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
    • Nguyen, V.Q., Co, C., and Li, J.J. (2001) Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411, 1068-1073
    • (2001) Nature , vol.411 , pp. 1068-1073
    • Nguyen, V.Q.1    Co, C.2    Li, J.J.3
  • 13
    • 26244435980 scopus 로고    scopus 로고
    • CDK phosphorylation of a novel NLSNES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication
    • Like, M.E., Nguyen, V.Q., Rosales, A.W., Irie, K., and Li, J.J. (2005) CDK phosphorylation of a novel NLSNES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol. Biol. Cell 16, 5026-5039
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5026-5039
    • Like, M.E.1    Nguyen, V.Q.2    Rosales, A.W.3    Irie, K.4    Li, J.J.5
  • 14
    • 0031037222 scopus 로고    scopus 로고
    • Construction by gene targeting in human cells of a 'conditional' CDC2 mutant that rereplicates its DNA
    • Itzhaki, J.E., Gilbert, C.S., and Porter, A.C. (1997) Construction by gene targeting in human cells of a 'conditional' CDC2 mutant that rereplicates its DNA. Nat. Genet. 15, 258-265
    • (1997) Nat. Genet , vol.15 , pp. 258-265
    • Itzhaki, J.E.1    Gilbert, C.S.2    Porter, A.C.3
  • 15
    • 0038512143 scopus 로고    scopus 로고
    • The ?ORC cycle?: A novel pathway for regulating eukaryotic DNA replication
    • DePamphilis, M.L. (2003) The ?ORC cycle?: a novel pathway for regulating eukaryotic DNA replication. Gene 310, 1-15
    • (2003) Gene , vol.310 , pp. 1-15
    • Depamphilis, M.L.1
  • 16
    • 28844501617 scopus 로고    scopus 로고
    • CDK phosphorylation inhibits the DNAbinding and ATP hydrolysis activities of the Drosophila origin recognition complex
    • Remus, D., Blanchette, M., Rio, D.C., and Botchan, M.R. (2005) CDK phosphorylation inhibits the DNAbinding and ATP hydrolysis activities of the Drosophila origin recognition complex. J. Biol. Chem. 280, 39740-39751
    • (2005) J. Biol. Chem , vol.280 , pp. 39740-39751
    • Remus, D.1    Blanchette, M.2    Rio, D.C.3    Botchan, M.R.4
  • 17
    • 79951713759 scopus 로고    scopus 로고
    • CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6
    • Chen, S. and Bell, S.P. (2011) CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6. Genes Dev. 25, 363-372
    • (2011) Genes Dev , vol.25 , pp. 363-372
    • Chen, S.1    Bell, S.P.2
  • 18
    • 25444485520 scopus 로고    scopus 로고
    • Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A
    • Zhu, Y., Ishimi, Y., Tanudji, M., and Lees, E. (2005) Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A. Cell Cycle 4, 1254-1263
    • (2005) Cell Cycle , vol.4 , pp. 1254-1263
    • Zhu, Y.1    Ishimi, Y.2    Tanudji, M.3    Lees, E.4
  • 19
    • 47749123322 scopus 로고    scopus 로고
    • Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells
    • Wheeler, L.W., Lents, N.H., and Baldassare, J.J. (2008) Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells. Cell Cycle 7, 2179-2188
    • (2008) Cell Cycle , vol.7 , pp. 2179-2188
    • Wheeler, L.W.1    Lents, N.H.2    Baldassare, J.J.3
  • 20
    • 0032479446 scopus 로고    scopus 로고
    • Cell cycle-and chromatin binding site-dependent phosphorylation of human MCM heterohexameric complexes
    • Fujita, M., Yamada, C., Tsurumi, T., Hanaoka, F., Matsuzawa, K., and Inagaki, M. (1998) Cell cycle-and chromatin binding site-dependent phosphorylation of human MCM heterohexameric complexes. J. Biol. Chem. 273, 17095-17101
    • (1998) J. Biol. Chem , vol.273 , pp. 17095-17101
    • Fujita, M.1    Yamada, C.2    Tsurumi, T.3    Hanaoka, F.4    Matsuzawa, K.5    Inagaki, M.6
  • 21
    • 0029861615 scopus 로고    scopus 로고
    • Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex
    • Hendrickson, M., Madine, M., Dalton, S., and Gautier, J. (1996) Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex. Proc. Natl Acad. Sci. U S A. 93, 12223-12228
    • (1996) Proc. Natl Acad. Sci. U S A , vol.93 , pp. 12223-12228
    • Hendrickson, M.1    Madine, M.2    Dalton, S.3    Gautier, J.4
  • 22
    • 84875710327 scopus 로고    scopus 로고
    • Protein interaction and cellular localization of human CDC45
    • Takaya, J., Kusunoki, S., and Ishimi, Y. (2013) Protein interaction and cellular localization of human CDC45. J. Biochem. 153, 381-388
    • (2013) J. Biochem , vol.153 , pp. 381-388
    • Takaya, J.1    Kusunoki, S.2    Ishimi, Y.3
  • 23
    • 0034717153 scopus 로고    scopus 로고
    • Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclinA/Cdk2
    • Ishimi, Y., Komamura-Kohno, Y., You, Z., Omori, A., and Kitagawa, M. (2000) Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclinA/Cdk2. J. Biol. Chem. 275, 16235-16241
    • (2000) J. Biol. Chem , vol.275 , pp. 16235-16241
    • Ishimi, Y.1    Komamura-Kohno, Y.2    You, Z.3    Omori, A.4    Kitagawa, M.5
  • 24
    • 0035860801 scopus 로고    scopus 로고
    • Phosphorylation of Mcm4 at specific sites by cyclindependent kinase leads to loss of Mcm4,6,7 helicase activity
    • Ishimi, Y. and Komamura-Kohno, Y. (2001) Phosphorylation of Mcm4 at specific sites by cyclindependent kinase leads to loss of Mcm4,6,7 helicase activity. J. Biol. Chem. 276, 34428-34433
    • (2001) J. Biol. Chem , vol.276 , pp. 34428-34433
    • Ishimi, Y.1    Komamura-Kohno, Y.2
  • 25
    • 74749095240 scopus 로고    scopus 로고
    • Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins
    • Ilves, I., Petojevic, T., Pesavento, J.J., and Botchan, M.R. (2010) Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. Mol. Cell 37, 247-258
    • (2010) Mol. Cell , vol.37 , pp. 247-258
    • Ilves, I.1    Petojevic, T.2    Pesavento, J.J.3    Botchan, M.R.4
  • 26
    • 47349114465 scopus 로고    scopus 로고
    • The Mcm2-7 complex has in vitro helicase activity
    • Bochman, M.L. and Schwacha, A. (2008) The Mcm2-7 complex has in vitro helicase activity. Mol. Cell 31, 287-293
    • (2008) Mol. Cell , vol.31 , pp. 287-293
    • Bochman, M.L.1    Schwacha, A.2
  • 27
    • 84859980381 scopus 로고    scopus 로고
    • Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase e in rolling circle DNA synthesis
    • Kang, Y.-H., Galal, W.C., Farina, A., Tappin, I., and Hurwitz, J. (2012) Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase e in rolling circle DNA synthesis. Proc. Natl Acad. Sci. U S A. 109, 6042-6047
    • (2012) Proc. Natl Acad. Sci. U S A , vol.109 , pp. 6042-6047
    • Kang, Y.-H.1    Galal, W.C.2    Farina, A.3    Tappin, I.4    Hurwitz, J.5
  • 28
    • 75749103708 scopus 로고    scopus 로고
    • Treslin collaborates with TopBP1 in triggering the initiation of DNA replication
    • Kumagai, A., Shevchenko, A., Shevchenko, A., and Dunphy, W.G. (2010) Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell 140, 349-359
    • (2010) Cell , vol.140 , pp. 349-359
    • Kumagai, A.1    Shevchenko, A.2    Shevchenko, A.3    Dunphy, W.G.4
  • 29
    • 33745471225 scopus 로고    scopus 로고
    • The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication
    • Matsuno, K., Kumamo, M., Kubota, Y., Hashimoto, Y., and Takisawa, H. (2006) The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. Mol. Cell. Biol. 26, 4843-4852
    • (2006) Mol. Cell. Biol , vol.26 , pp. 4843-4852
    • Matsuno, K.1    Kumamo, M.2    Kubota, Y.3    Hashimoto, Y.4    Takisawa, H.5
  • 30
    • 0043092109 scopus 로고    scopus 로고
    • Identification of MCM4 as a target of the DNA replication block checkpoint system
    • Ishimi, Y., Komamura-Kohno, Y., Kwon, H.-J., Yamada, K., and Nakanishi, M. (2003) Identification of MCM4 as a target of the DNA replication block checkpoint system. J. Biol. Chem. 278, 24644-24650
    • (2003) J. Biol. Chem , vol.278 , pp. 24644-24650
    • Ishimi, Y.1    Komamura-Kohno, Y.2    Kwon, H.-J.3    Yamada, K.4    Nakanishi, M.5
  • 31
  • 32
    • 70449732463 scopus 로고    scopus 로고
    • DNA helicase activity in purified human RECQL4 protein
    • Suzuki, T., Kohno, T., and Ishimi, Y. (2009) DNA helicase activity in purified human RECQL4 protein. J. Biochem. 146, 327-335
    • (2009) J. Biochem , vol.146 , pp. 327-335
    • Suzuki, T.1    Kohno, T.2    Ishimi, Y.3
  • 33
    • 66249137141 scopus 로고    scopus 로고
    • Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase
    • Ishimi, Y., Sugiyama, T., Nakaya, R., Kanamori, M., Kohno, T., Enomoto, T., and Chino, M. (2009) Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase. FEBS J. 276, 3382-3391
    • (2009) FEBS J , vol.276 , pp. 3382-3391
    • Ishimi, Y.1    Sugiyama, T.2    Nakaya, R.3    Kanamori, M.4    Kohno, T.5    Enomoto, T.6    Chino, M.7
  • 34
    • 0028074229 scopus 로고
    • DNA polymerase a associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period
    • Kimura, H., Nozaki, N., and Sugimoto, K. (1994) DNA polymerase a associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. EMBO J. 13, 4311-4320
    • (1994) EMBO J , vol.13 , pp. 4311-4320
    • Kimura, H.1    Nozaki, N.2    Sugimoto, K.3
  • 35
    • 0029058498 scopus 로고
    • Molecular cloning of cDNA encoding mouse Cdc21 and Cdc46 homologs and characterization of the products: Physical interaction between P1(MCM3) and CDC46 proteins
    • Kimura, H., Takisawa, N., Nozaki, N., and Sugimoto, K. (1995) Molecular cloning of cDNA encoding mouse Cdc21 and Cdc46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins. Nucleic Acids Res. 23, 2097-2104
    • (1995) Nucleic Acids Res , vol.23 , pp. 2097-2104
    • Kimura, H.1    Takisawa, N.2    Nozaki, N.3    Sugimoto, K.4
  • 38
    • 79959399046 scopus 로고    scopus 로고
    • Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication
    • Kumagai, A., Shevchenko, A., Shevchenko, A., and Dunphy, W.G. (2011) Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J. Cell Biol 193, 995-1007
    • (2011) J. Cell Biol , vol.193 , pp. 995-1007
    • Kumagai, A.1    Shevchenko, A.2    Shevchenko, A.3    Dunphy, W.G.4
  • 39
    • 77957149919 scopus 로고    scopus 로고
    • Checkpoint dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation
    • Zegerman, P. and Diffley, J.F.X. (2010) Checkpoint dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 467, 474-478
    • (2010) Nature , vol.467 , pp. 474-478
    • Zegerman, P.1    Diffley, J.F.X.2
  • 41
    • 37249080597 scopus 로고    scopus 로고
    • Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair
    • Anantha, R.W., Vassin, V.M., and Borowiec, J.A. (2007) Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair. J. Biol. Chem. 282, 35910-35923
    • (2007) J. Biol. Chem , vol.282 , pp. 35910-35923
    • Anantha, R.W.1    Vassin, V.M.2    Borowiec, J.A.3
  • 43
    • 84865188025 scopus 로고    scopus 로고
    • Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex
    • Ilver, I., Tamberg, N., and Botchan, M.R. (2012) Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex. Proc. Natl Acad. Sci. U S A. 109, 13163-13170
    • (2012) Proc. Natl Acad. Sci. U S A , vol.109 , pp. 13163-13170
    • Ilver, I.1    Tamberg, N.2    Botchan, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.