Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override

Cell Cycle

Volumn 12, Issue 10, 2013, Pages 1588-1597

  Beeharry, Neil ^a   Rattner, Jerome B ^b   Caviston, Juliane P ^a,c   Yen, Tim ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Cell cycle checkpoints; Centromere; DNA damage; Mitotic catastrophe; MUGs

Indexed keywords

DOXORUBICIN; ETOPOSIDE; 7-HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; CHECKPOINT KINASE 1; DEOXYCYTIDINE; DNA TOPOISOMERASE (ATP HYDROLYSING); GEMCITABINE; GYRASE INHIBITOR; PROTEIN KINASE; STAUROSPORINE;

ARTICLE; CANCER CELL; CELL VIABILITY; CENTROMERE FRAGMENTATION; CHROMOSOME ABERRATION; COMET ASSAY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; PANCREAS CANCER; S PHASE CELL CYCLE CHECKPOINT; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CENTROMERE; CHEMISTRY; CHO CELL LINE; CRICETULUS; DNA DAMAGE; DRUG EFFECTS; HAMSTER; HELA CELL LINE; METABOLISM; MITOSIS; TOXICITY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CENTROMERE; CHO CELLS; COMET ASSAY; CRICETINAE; CRICETULUS; DEOXYCYTIDINE; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; DOXORUBICIN; ETOPOSIDE; G2 PHASE CELL CYCLE CHECKPOINTS; HELA CELLS; HUMANS; KINETOCHORES; MITOSIS; PROTEIN KINASES; S PHASE CELL CYCLE CHECKPOINTS; STAUROSPORINE; TOPOISOMERASE II INHIBITORS;

EID: 84877949027     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24740     Document Type: Article

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