News from the protein mutability landscape

Journal of Molecular Biology

Volumn 425, Issue 21, 2013, Pages 3937-3948

  Hecht, Maximilian ^a   Bromberg, Yana ^b   Rost, Burkhard ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

alanine scanning; complete single mutagenesis; exome wide mutagenesis; in silico mutagenesis; SNP effects

Indexed keywords

ALANINE; AMINO ACID; G PROTEIN COUPLED RECEPTOR; PROTEIN; PROTEIN P53;

COMPUTER MODEL; EXOME; GENETIC VARIABILITY; GENOTYPE; HUMAN; MISSENSE MUTATION; MUTAGENESIS; MUTATION; NONHUMAN; PATHOGENICITY; PHENOTYPE; POINT MUTATION; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW;

3D; ALANINE SCANNING; COMPLETE SINGLE MUTAGENESIS; EXOME-WIDE MUTAGENESIS; G-PROTEIN-COUPLED RECEPTOR; GPCR; HMC4R; HUMAN MELANOCORTIN 4 RECEPTOR; IN SILICO MUTAGENESIS; NON-SYNONYMOUS SNP; NSSNP; PDB; PROTEIN DATA BANK; SAAS; SCREENING FOR NON-ACCEPTABLE POLYMORPHISMS; SIFT; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE-AMINO-ACID SUBSTITUTION; SNAP; SNP; SNP EFFECTS; SORTING INTOLERANT FROM TOLERANT; THREE-DIMENSIONAL;

COMPUTATIONAL BIOLOGY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MODELS, MOLECULAR; MUTATION, MISSENSE; POINT MUTATION; PROTEIN STABILITY; PROTEINS;

EID: 85047688149     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.07.028     Document Type: Review

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