Correlated mutations: A hallmark of phenotypic amino acid substitutions

PLoS Computational Biology

Volumn 6, Issue 9, 2010, Pages

  Kowarsch, Andreas ^a,b   Fuchs, Angelika ^a   Frishman, Dmitrij ^a,b   Pagel, Philipp ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINS;

AMINO ACID SUBSTITUTION; AMINO-ACIDS; CO-EVOLUTION; COMPREHENSIVE ANALYSIS; EVOLUTIONARY CONSERVATIONS; FUNCTIONAL SITES; NATURALLY OCCURRING; POINT MUTATIONS; SEQUENCE MOTIFS; SYSTEMATIC ANALYSIS;

AMINO ACIDS;

ADENYLATE KINASE; ADENYLATE KINASE 1; PROLINE DIPEPTIDASE; UNCLASSIFIED DRUG;

ALGORITHM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CLUSTER ANALYSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVE SITE; GENETIC CONSERVATION; GENETIC CORRELATION; HEMOLYTIC ANEMIA; HUMAN; MUTATIONAL ANALYSIS; PHENOTYPE; POINT MUTATION; PREDICTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 78049444976     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000923     Document Type: Article

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