메뉴 건너뛰기




Volumn 15, Issue 1, 2018, Pages

Cannabinoid CB 2 receptors in the mouse brain: Relevance for Alzheimer's disease

Author keywords

Amyloid; Cannabinoid CB 2 receptor; Enhanced green fluorescent protein; Microglia; Neuroinflammation; Transgenic mice

Indexed keywords

AMYLOID; CANNABINOID 2 RECEPTOR; ENHANCED GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1BETA; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); CALCIUM BINDING PROTEIN; CD11B ANTIGEN; ENOLASE; GREEN FLUORESCENT PROTEIN; PEPTIDE FRAGMENT;

EID: 85047540052     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-018-1174-9     Document Type: Article
Times cited : (103)

References (40)
  • 1
    • 84878863032 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice
    • Aso E, Juvés S, Maldonado R, Ferrer I. CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice. J Alz Dis. 2013;35:847-858.
    • (2013) J Alz Dis , vol.35 , pp. 847-858
    • Aso, E.1    Juvés, S.2    Maldonado, R.3    Ferrer, I.4
  • 2
    • 84961770701 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 participates in amyloid-β processing in a mouse model of Alzheimer's disease but plays a minor role in the therapeutic properties of a cannabis-based medicine
    • Aso E, Andrés-Benito P, Carmona M, Maldonado R, Ferrer I. Cannabinoid receptor 2 participates in amyloid-β processing in a mouse model of Alzheimer's disease but plays a minor role in the therapeutic properties of a cannabis-based medicine. J Alz Dis. 2016;51:489-500.
    • (2016) J Alz Dis. , vol.51 , pp. 489-500
    • Aso, E.1    Andrés-Benito, P.2    Carmona, M.3    Maldonado, R.4    Ferrer, I.5
  • 3
    • 77952623444 scopus 로고    scopus 로고
    • CB2: a cannabinoid receptor with an identity crisis
    • Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol. 2010;160:467-79.
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    Mackie, K.2
  • 5
    • 0348010292 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains
    • Benito C, Nunez E, Tolon RM, Carrier EJ, Rabano A, Hillard CJ, Romero J. Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. J Neurosci. 2003;23:11136-41.
    • (2003) J Neurosci , vol.23 , pp. 11136-11141
    • Benito, C.1    Nunez, E.2    Tolon, R.M.3    Carrier, E.J.4    Rabano, A.5    Hillard, C.J.6    Romero, J.7
  • 8
    • 84942511296 scopus 로고    scopus 로고
    • Endocannabinoids and the immune system in health and disease
    • Cabral GA, Ferrerira GA, Jamerson MJ. Endocannabinoids and the immune system in health and disease. Handb Exp Pharmacol. 2015;231:185-211.
    • (2015) Handb Exp Pharmacol , vol.231 , pp. 185-211
    • Cabral, G.A.1    Ferrerira, G.A.2    Jamerson, M.J.3
  • 9
    • 0035191240 scopus 로고    scopus 로고
    • Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    • Carlisle SJ, Marciano-Cabral F, Staab A, Ludwick C, Cabral GA. Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation. Int Immunopharmacol. 2002;2:69-82.
    • (2002) Int Immunopharmacol , vol.2 , pp. 69-82
    • Carlisle, S.J.1    Marciano-Cabral, F.2    Staab, A.3    Ludwick, C.4    Cabral, G.A.5
  • 10
    • 34548069374 scopus 로고    scopus 로고
    • Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence
    • Esposito G, Iuvone T, Savani C, Scuderi C, De Filippis D, Papa M, DiMarzo V, Steardo L. Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. J Pharmacol Exp Ther. 2007;322:1144-52.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 1144-1152
    • Esposito, G.1    Iuvone, T.2    Savani, C.3    Scuderi, C.4    De Filippis, D.5    Papa, M.6    DiMarzo, V.7    Steardo, L.8
  • 14
  • 15
    • 84868121639 scopus 로고    scopus 로고
    • Murine spleen contains a diversity of myeloid and dendritic cells distinct in antigen presenting function
    • Hey YY, O'Neill HC. Murine spleen contains a diversity of myeloid and dendritic cells distinct in antigen presenting function. J Cell Mol Med. 2012;16:2611-9.
    • (2012) J Cell Mol Med , vol.16 , pp. 2611-2619
    • Hey, Y.Y.1    O'Neill, H.C.2
  • 16
    • 84893494322 scopus 로고    scopus 로고
    • CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease
    • Koppel J, Vingtdeux V, Marambaud P, D'Abramo C, Jimenez H, Stauber M, Friedman R, Davies P. CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease. Mol Med. 2014;20:29-36.
    • (2014) Mol Med , vol.20 , pp. 29-36
    • Koppel, J.1    Vingtdeux, V.2    Marambaud, P.3    D'Abramo, C.4    Jimenez, H.5    Stauber, M.6    Friedman, R.7    Davies, P.8
  • 17
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein ES, et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature. 2007;445:168-76.
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1
  • 18
    • 0028325790 scopus 로고
    • Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids
    • Lynn AB, Herkenham M. Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids. J Pharmacol Exp Ther. 1994;268:1612-23.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1612-1623
    • Lynn, A.B.1    Herkenham, M.2
  • 19
    • 26844448746 scopus 로고    scopus 로고
    • Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
    • Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem. 2005;95:437-45.
    • (2005) J Neurochem , vol.95 , pp. 437-445
    • Maresz, K.1    Carrier, E.J.2    Ponomarev, E.D.3    Hillard, C.J.4    Dittel, B.N.5
  • 23
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature. 1993;365:61-5.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 24
    • 3843066799 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors are expressed by perivascular microglial cells in the human brain: an immunohistochemical study
    • Nuñez E, Benito C, Pazos MR, Barbachano A, Fajardo O, González S, Tolón RM, Romero J. Cannabinoid CB2 receptors are expressed by perivascular microglial cells in the human brain: an immunohistochemical study. Synapse. 2004;53:208-13.
    • (2004) Synapse , vol.53 , pp. 208-213
    • Nuñez, E.1    Benito, C.2    Pazos, M.R.3    Barbachano, A.4    Fajardo, O.5    González, S.6    Tolón, R.M.7    Romero, J.8
  • 25
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
    • Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J Neurosci. 2006;26:10129-40.
    • (2006) J Neurosci , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10    Berry, R.11    Vassar, R.12
  • 26
    • 14244264502 scopus 로고    scopus 로고
    • Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation
    • Ramírez BG, Blázquez C, Gómez del Pulgar T, Guzmán M, de Ceballos ML. Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J Neurosci. 2005;23:1904-13.
    • (2005) J Neurosci , vol.23 , pp. 1904-1913
    • Ramírez, B.G.1    Blázquez, C.2    Gómez del Pulgar, T.3    Guzmán, M.4    de Ceballos, M.L.5
  • 31
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
    • Stella N. Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. Glia. 2010;58:1017-30.
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 33
    • 67651121672 scopus 로고    scopus 로고
    • The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages
    • Tolón RM, Núñez E, Pazos MR, Benito C, Castillo AI, Martínez-Orgado JA, Romero J. The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. Brain Res. 2009;1283:148-54.
    • (2009) Brain Res , vol.1283 , pp. 148-154
    • Tolón, R.M.1    Núñez, E.2    Pazos, M.R.3    Benito, C.4    Castillo, A.I.5    Martínez-Orgado, J.A.6    Romero, J.7
  • 38
    • 84870489074 scopus 로고    scopus 로고
    • Activation of the CB2 receptor system reverses amyloid-induced memory deficiency
    • Wu J, Bie B, Yang H, Xu JJ, Brown DL, Naguib M. Activation of the CB2 receptor system reverses amyloid-induced memory deficiency. Neurobiol Ag. 2013;34:791-804.
    • (2013) Neurobiol Ag. , vol.34 , pp. 791-804
    • Wu, J.1    Bie, B.2    Yang, H.3    Xu, J.J.4    Brown, D.L.5    Naguib, M.6
  • 39
    • 84915754556 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
    • Zhang HY, Gao M, Liu QR, Bi GH, Li X, Gardner EL, Wu J, Xi ZX. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proc Natl Acad Sci U S A. 2014;111:E5007-15.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. E5007-E5015
    • Zhang, H.Y.1    Gao, M.2    Liu, Q.R.3    Bi, G.H.4    Li, X.5    Gardner, E.L.6    Wu, J.7    Xi, Z.X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.