Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

Nature

Volumn 557, Issue 7706, 2018, Pages 580-584

  Meisel, Marlies ^a   Hinterleitner, Reinhard ^a   Pacis, Alain ^b,c   Chen, Li ^a   Earley, Zachary M ^a   Mayassi, Toufic ^a   Pierre, Joseph F ^a,d   Ernest, Jordan D ^a   Galipeau, Heather J ^e   Thuille, Nikolaus ^f   Bouziat, Romain ^a   Buscarlet, Manuel ^g   Ringus, Daina L ^a   Wang, Yitang ^a   Li, Ye ^a   DInh, Vu ^a   Kim, Sangman M ^a   McDonald, Benjamin D ^a   Zurenski, Matthew A ^a   Musch, Mark W ^a   Furtado, Glaucia C ^h   Lira, Sergio A ^h   Baier, Gottfried ^f   Chang, Eugene B ^a   Eren, A Murat ^a,i   Weber, Christopher R ^a   Busque, Lambert ^g   Godley, Lucy A ^a   Verdú, Elena F ^e   Barreiro, Luis B ^b,c   Jabri, Bana ^a   more..

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e MCMASTER UNIVERSITY   (Canada)

^f INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^g MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

ⁱ MARINE BIOLOGICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLISTIN; GENTAMICIN; INTERLEUKIN 6; KANAMYCIN; METRONIDAZOLE; TOLL LIKE RECEPTOR AGONIST; VANCOMYCIN; DNA BINDING PROTEIN; ONCOPROTEIN; TET2 PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2;

ANTIBIOTICS; BACTERIUM; CELL COMPONENT; ENZYME; ENZYME ACTIVITY; MICROBIAL ACTIVITY; MUTATION; PROTEIN; SYMPTOM; TRANSLOCATION; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; CANCER RISK; CELL LINEAGE; COLITIS; COLONY FORMING UNIT GM; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE MUTATION; HEMATOPOIETIC STEM CELL; INTESTINE MUCOSA PERMEABILITY; LACTOBACILLUS; LEUKEMOGENESIS; MOUSE; MYELOPOIESIS; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STAINING; STEM CELL SELF-RENEWAL; TET2 GENE; TREATMENT DURATION; AGONISTS; ANIMAL; ASYMPTOMATIC DISEASE; BACTERIAL INFECTION; BACTERIAL PHENOMENA AND FUNCTIONS; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DEFICIENCY; FEMALE; GENETICS; GERMFREE ANIMAL; IMMUNOLOGY; INFLAMMATION; INTESTINE; LEUKEMIA; MALE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PENETRANCE; PERMEABILITY;

BACTERIA (MICROORGANISMS); MUS;

ANIMALS; ASYMPTOMATIC DISEASES; BACTERIAL INFECTIONS; BACTERIAL PHYSIOLOGICAL PHENOMENA; CELL PROLIFERATION; DNA-BINDING PROTEINS; FEMALE; GERM-FREE LIFE; INFLAMMATION; INTERLEUKIN-6; INTESTINES; LACTOBACILLUS; LEUKEMIA; MALE; MICE; PENETRANCE; PERMEABILITY; PROTO-ONCOGENE PROTEINS; TOLL-LIKE RECEPTOR 2;

EID: 85047496024     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-018-0125-z     Document Type: Article

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