Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide

Food and Chemical Toxicology

Volumn 118, Issue , 2018, Pages 154-167

  Knickle, Allison ^a   Fernando, Wasundara ^a   Greenshields, Anna L ^a   Rupasinghe, H P Vasantha ^a,b   Hoskin, David W ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Apoptosis; Breast cancer; Mitochondria; Myricetin; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; CATALASE; CISPLATIN; CYTOCHROME C; DEFERIPRONE; DOXORUBICIN; EPIGALLOCATECHIN GALLATE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYRICETIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SUPEROXIDE DISMUTASE; ANTINEOPLASTIC AGENT; FLAVONOID; IRON;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; FENTON REACTION; HUMAN; HUMAN CELL; MDA-MB-231 CELL LINE; MDA-MB-468 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN SECRETION; TRIPLE NEGATIVE BREAST CANCER; WESTERN BLOTTING; CELL PROLIFERATION; DNA DAMAGE; DRUG EFFECT; ENZYMOLOGY; FEMALE; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CATALASE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; FEMALE; FLAVONOIDS; HUMANS; HYDROGEN PEROXIDE; IRON; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 85047072835     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2018.05.005     Document Type: Article

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