메뉴 건너뛰기




Volumn 36, Issue 1, 2016, Pages 342-348

Myricetin suppresses p21-activated kinase 1 in human breast cancer MCF-7 cells through downstream signaling of the β-catenin pathway

Author keywords

Human breast cancer; Myricetin; p21 activated kinase 1; catenin

Indexed keywords

BETA CATENIN; CASPASE 3; CYCLIN D1; CYCLINE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MYRICETIN; P21 ACTIVATED KINASE 1; PROTEIN BAX; SURVIVIN; BIRC5 PROTEIN, HUMAN; FLAVONOID; GLYCOGEN SYNTHASE KINASE 3; INHIBITOR OF APOPTOSIS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; P21 ACTIVATED KINASE; PAK1 PROTEIN, HUMAN;

EID: 84971472928     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2016.4777     Document Type: Article
Times cited : (45)

References (30)
  • 1
    • 84929941054 scopus 로고    scopus 로고
    • A prospective feasibility study of sentinel node biopsy by modified Indigocarmine blue dye methods after neoadjuvant chemotherapy for breast cancer
    • Kida K, Ishikawa T, Yamada A, Shimizu D, Tanabe M, Sasaki T, Ichikawa Y and Endo I: A prospective feasibility study of sentinel node biopsy by modified Indigocarmine blue dye methods after neoadjuvant chemotherapy for breast cancer. Eur J Surg Oncol 41: 566-570, 2015.
    • (2015) Eur J Surg Oncol , vol.41 , pp. 566-570
    • Kida, K.1    Ishikawa, T.2    Yamada, A.3    Shimizu, D.4    Tanabe, M.5    Sasaki, T.6    Ichikawa, Y.7    Endo, I.8
  • 2
    • 84886408077 scopus 로고    scopus 로고
    • Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial
    • Perez EA, Dueck AC, McCullough AE, Chen B, Geiger XJ, Jenkins RB, Lingle WL, Davidson NE, Martino S, Kaufman PA, et al: Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial. J Clin Oncol 31: 2115-2122, 2013.
    • (2013) J Clin Oncol , vol.31 , pp. 2115-2122
    • Perez, E.A.1    Dueck, A.C.2    McCullough, A.E.3    Chen, B.4    Geiger, X.J.5    Jenkins, R.B.6    Lingle, W.L.7    Davidson, N.E.8    Martino, S.9    Kaufman, P.A.10
  • 3
    • 84877132818 scopus 로고    scopus 로고
    • Higher rate of skin rash in a phase II trial with weekly nanoparticle albumin-bound paclitaxel and cisplatin combination in Chinese breast cancer patients
    • Tang LC, Wang BY, Sun S, Zhang J, Jia Z, Lu YH, Di GH, Shao ZM and Hu XC: Higher rate of skin rash in a phase II trial with weekly nanoparticle albumin-bound paclitaxel and cisplatin combination in Chinese breast cancer patients. BMC Cancer 13: 232, 2013.
    • (2013) BMC Cancer , vol.13 , pp. 232
    • Tang, L.C.1    Wang, B.Y.2    Sun, S.3    Zhang, J.4    Jia, Z.5    Lu, Y.H.6    Di, G.H.7    Shao, Z.M.8    Hu, X.C.9
  • 5
    • 84927759580 scopus 로고    scopus 로고
    • Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer
    • Khare V, Dammann K, Asboth M, Krnjic A, Jambrich M and Gasche C: Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer. Inflamm Bowel Dis 21: 287-296, 2015.
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 287-296
    • Khare, V.1    Dammann, K.2    Asboth, M.3    Krnjic, A.4    Jambrich, M.5    Gasche, C.6
  • 6
    • 84864390450 scopus 로고    scopus 로고
    • Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-cells
    • Nie J, Sun C, Faruque O, Ye G, Li J, Liang Q, Chang Z, Yang W, Han X and Shi Y: Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-cells. J Biol Chem 287: 26435-26444, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 26435-26444
    • Nie, J.1    Sun, C.2    Faruque, O.3    Ye, G.4    Li, J.5    Liang, Q.6    Chang, Z.7    Yang, W.8    Han, X.9    Shi, Y.10
  • 8
    • 84952657492 scopus 로고    scopus 로고
    • CONSORT: Sam68 is directly regulated by miR-204 and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway
    • Wang L, Tian H, Yuan J, Wu H, Wu J and Zhu X: CONSORT: Sam68 is directly regulated by miR-204 and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway. Medicine 94: e2228, 2015.
    • (2015) Medicine , vol.94
    • Wang, L.1    Tian, H.2    Yuan, J.3    Wu, H.4    Wu, J.5    Zhu, X.6
  • 9
    • 84941243535 scopus 로고    scopus 로고
    • Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth
    • Dong Y, Cao B, Zhang M, Han W, Herman JG, Fuks F, Zhao Y and Guo M: Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth. Oncotarget 6: 22126-22138, 2015.
    • (2015) Oncotarget , vol.6 , pp. 22126-22138
    • Dong, Y.1    Cao, B.2    Zhang, M.3    Han, W.4    Herman, J.G.5    Fuks, F.6    Zhao, Y.7    Guo, M.8
  • 10
    • 84897073421 scopus 로고    scopus 로고
    • Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway
    • Kim ME, Ha TK, Yoon JH and Lee JS: Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway. Anticancer Res 34: 701-706, 2014.
    • (2014) Anticancer Res , vol.34 , pp. 701-706
    • Kim, M.E.1    Ha, T.K.2    Yoon, J.H.3    Lee, J.S.4
  • 11
    • 84939268353 scopus 로고    scopus 로고
    • Myricetin induces apoptosis by inhibiting P21 activated kinase 1 (PAK1) signaling cascade in hepatocellular carcinoma
    • Iyer SC, Gopal A and Halagowder D: Myricetin induces apoptosis by inhibiting P21 activated kinase 1 (PAK1) signaling cascade in hepatocellular carcinoma. Mol Cell Biochem 407: 223-237, 2015.
    • (2015) Mol Cell Biochem , vol.407 , pp. 223-237
    • Iyer, S.C.1    Gopal, A.2    Halagowder, D.3
  • 12
    • 84883702331 scopus 로고    scopus 로고
    • Enhancing effect of a cysteinyl thiol on the antioxidant activity of flavonoids and identification of the antioxidative thiol adducts of myricetin
    • Masuda T, Miura Y, Inai M and Masuda A: Enhancing effect of a cysteinyl thiol on the antioxidant activity of flavonoids and identification of the antioxidative thiol adducts of myricetin. Biosci Biotechnol Biochem 77: 1753-1758, 2013.
    • (2013) Biosci Biotechnol Biochem , vol.77 , pp. 1753-1758
    • Masuda, T.1    Miura, Y.2    Inai, M.3    Masuda, A.4
  • 13
    • 78650986713 scopus 로고    scopus 로고
    • Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways
    • Kang KA, Wang ZH, Zhang R, Piao MJ, Kim KC, Kang SS, Kim YW, Lee J, Park D and Hyun JW: Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways. Int J Mol Sci 11: 4348-4360, 2010.
    • (2010) Int J Mol Sci , vol.11 , pp. 4348-4360
    • Kang, K.A.1    Wang, Z.H.2    Zhang, R.3    Piao, M.J.4    Kim, K.C.5    Kang, S.S.6    Kim, Y.W.7    Lee, J.8    Park, D.9    Hyun, J.W.10
  • 14
    • 84895477605 scopus 로고    scopus 로고
    • Cost-utility analysis of individual psychosocial support interventions for breast cancer patients in a randomized controlled study
    • Arving C, Brandberg Y, Feldman I, Johansson B and Glimelius B: Cost-utility analysis of individual psychosocial support interventions for breast cancer patients in a randomized controlled study. Psychooncology 23: 251-258, 2014.
    • (2014) Psychooncology , vol.23 , pp. 251-258
    • Arving, C.1    Brandberg, Y.2    Feldman, I.3    Johansson, B.4    Glimelius, B.5
  • 15
    • 84924614699 scopus 로고    scopus 로고
    • A phase II trial of biweekly vinorelbine and oxaliplatin in second- or third-line metastatic triple-negative breast cancer
    • Zhang J, Wang L, Wang Z, Hu X, Wang B, Cao J, Lv F, Zhen C, Zhang S and Shao Z: A phase II trial of biweekly vinorelbine and oxaliplatin in second- or third-line metastatic triple-negative breast cancer. Cancer Biol Ther 16: 225-232, 2015.
    • (2015) Cancer Biol Ther , vol.16 , pp. 225-232
    • Zhang, J.1    Wang, L.2    Wang, Z.3    Hu, X.4    Wang, B.5    Cao, J.6    Lv, F.7    Zhen, C.8    Zhang, S.9    Shao, Z.10
  • 16
    • 84892867850 scopus 로고    scopus 로고
    • P21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes
    • DeSantiago J, Bare DJ, Xiao L, Ke Y, Solaro RJ and Banach K: p21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes. J Mol Cell Cardiol 67: 77-85, 2014.
    • (2014) J Mol Cell Cardiol , vol.67 , pp. 77-85
    • DeSantiago, J.1    Bare, D.J.2    Xiao, L.3    Ke, Y.4    Solaro, R.J.5    Banach, K.6
  • 18
    • 33646940460 scopus 로고    scopus 로고
    • Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
    • Holm C, Rayala S, Jirström K, Stål O, Kumar R and Landberg G: Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst 98: 671-680, 2006.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 671-680
    • Holm, C.1    Rayala, S.2    Jirström, K.3    Stål, O.4    Kumar, R.5    Landberg, G.6
  • 19
    • 59549099037 scopus 로고    scopus 로고
    • PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics
    • Smith SD, Jaffer ZM, Chernoff J and Ridley AJ: PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J Cell Sci 121: 3729-3736, 2008.
    • (2008) J Cell Sci , vol.121 , pp. 3729-3736
    • Smith, S.D.1    Jaffer, Z.M.2    Chernoff, J.3    Ridley, A.J.4
  • 21
    • 77957775196 scopus 로고    scopus 로고
    • Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells
    • Tarkkonen K, Ruohola J and Härkönen P: Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells. Growth Factors 28: 256-267, 2010.
    • (2010) Growth Factors , vol.28 , pp. 256-267
    • Tarkkonen, K.1    Ruohola, J.2    Härkönen, P.3
  • 22
    • 84880145058 scopus 로고    scopus 로고
    • ABCG2 protects kidney side population cells from hypoxia/reoxygenation injury through activation of the MEK/ERK pathway
    • Liu WH, Liu HB, Gao DK, Ge GQ, Zhang P, Sun SR, Wang HM and Liu SB: ABCG2 protects kidney side population cells from hypoxia/reoxygenation injury through activation of the MEK/ERK pathway. Cell Transplant 22: 1859-1868, 2013.
    • (2013) Cell Transplant , vol.22 , pp. 1859-1868
    • Liu, W.H.1    Liu, H.B.2    Gao, D.K.3    Ge, G.Q.4    Zhang, P.5    Sun, S.R.6    Wang, H.M.7    Liu, S.B.8
  • 23
    • 4444336822 scopus 로고    scopus 로고
    • Docetaxel cytotoxicity is enhanced by inhibition of the Raf/MEK/ERK signal transduction pathway
    • Navolanic PM, Lee JT and McCubrey JA: Docetaxel cytotoxicity is enhanced by inhibition of the Raf/MEK/ERK signal transduction pathway. Cancer Biol Ther 2: 677-678, 2003.
    • (2003) Cancer Biol Ther , vol.2 , pp. 677-678
    • Navolanic, P.M.1    Lee, J.T.2    McCubrey, J.A.3
  • 24
    • 84944883219 scopus 로고    scopus 로고
    • MiR-199a/b-3p suppresses migration and invasion of breast cancer cells by downregulating PAK4/MEK/ERK signaling pathway
    • Li SQ, Wang ZH, Mi XG, Liu L and Tan Y: MiR-199a/b-3p suppresses migration and invasion of breast cancer cells by downregulating PAK4/MEK/ERK signaling pathway. IUBMB Life 67: 768-777, 2015.
    • (2015) IUBMB Life , vol.67 , pp. 768-777
    • Li, S.Q.1    Wang, Z.H.2    Mi, X.G.3    Liu, L.4    Tan, Y.5
  • 25
    • 79955648857 scopus 로고    scopus 로고
    • Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signaling pathway in mouse epidermal cells
    • Lim TG, Lee BK, Kwon JY, Jung SK and Lee KW: Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signaling pathway in mouse epidermal cells. Food Chem Toxicol 49: 1249-1254, 2011.
    • (2011) Food Chem Toxicol , vol.49 , pp. 1249-1254
    • Lim, T.G.1    Lee, B.K.2    Kwon, J.Y.3    Jung, S.K.4    Lee, K.W.5
  • 26
    • 84878449765 scopus 로고    scopus 로고
    • Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6
    • Zhang J, Yang Z, Li P, Bledsoe G, Chao L and Chao J: Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6. Mol Cell Biochem 379: 295-301, 2013.
    • (2013) Mol Cell Biochem , vol.379 , pp. 295-301
    • Zhang, J.1    Yang, Z.2    Li, P.3    Bledsoe, G.4    Chao, L.5    Chao, J.6
  • 28
    • 84884280193 scopus 로고    scopus 로고
    • WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells
    • Prasad CP, Chaurasiya SK, Axelsson L and Andersson T: WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells. Mol Oncol 7: 870-883, 2013.
    • (2013) Mol Oncol , vol.7 , pp. 870-883
    • Prasad, C.P.1    Chaurasiya, S.K.2    Axelsson, L.3    Andersson, T.4
  • 29
    • 84916226237 scopus 로고    scopus 로고
    • RelB regulates Bcl-xl expression and the irradiation-induced apoptosis of murine prostate cancer cells
    • Zhu L, Zhu B, Yang L, Zhao X, Jiang H and Ma F: RelB regulates Bcl-xl expression and the irradiation-induced apoptosis of murine prostate cancer cells. Biomed Rep 2: 354-358, 2014.
    • (2014) Biomed Rep , vol.2 , pp. 354-358
    • Zhu, L.1    Zhu, B.2    Yang, L.3    Zhao, X.4    Jiang, H.5    Ma, F.6
  • 30
    • 84971487174 scopus 로고    scopus 로고
    • Effects of methylglyoxal and glyoxalase I inhibition on breast Cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2
    • Guo Y, Zhang Y, Yang X, Lu P, Yan X, Xiao F, Zhou H, Wen C, Shi M, Lu J, et al: Effects of methylglyoxal and glyoxalase I inhibition on breast Cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2. Cancer Biol Ther: 1-12, 2015.
    • (2015) Cancer Biol Ther , pp. 1-12
    • Guo, Y.1    Zhang, Y.2    Yang, X.3    Lu, P.4    Yan, X.5    Xiao, F.6    Zhou, H.7    Wen, C.8    Shi, M.9    Lu, J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.