Major contribution of the RNA-binding domain of NS1 in the pathogenicity and replication potential of an avian H7N1 influenza virus in chickens

Virology Journal

Volumn 15, Issue 1, 2018, Pages

  Trapp, Sascha ^a,b   Soubieux, Denis ^a,b   Lidove, Alexandra ^a,b   Esnault, Evelyne ^a,b   Lion, Adrien ^a,b   Guillory, Vanaique ^a,b   Wacquiez, Alan ^a,b   Kut, Emmanuel ^a,b   Quéré, Pascale ^a,b   Larcher, Thibaut ^c   Ledevin, Mireille ^c   Nadan, Virginie ^d   Camus Bouclainville, Christelle ^e   Marc, Daniel ^a,b  

^a UR1282   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c LUNAM UNIVERSITÉ   (France)

^d CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^e UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Chicken; Influenza A; NS1; Viral replication

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON; NONSTRUCTURAL PROTEIN 1; NUCLEOPROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; RNA POLYMERASE; INS1 PROTEIN, INFLUENZA VIRUS; RNA DIRECTED RNA POLYMERASE; VIRAL PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA VIRUS; CHICKEN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EFFECTOR DOMAIN; GENETIC ENGINEERING; IN VITRO STUDY; IN VIVO STUDY; LIFE CYCLE; LUNG EPITHELIUM; NONHUMAN; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA-BINDING DOMAIN; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; AVIAN INFLUENZA; BIOSYNTHESIS; CELL LINE; CHICK EMBRYO; DISEASE MODEL; DOG; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; INFLUENZA A VIRUS (H7N1); MDCK CELL LINE; METABOLISM; PATHOGENICITY; PHYSIOLOGY; VIROLOGY; VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CHICK EMBRYO; CHICKENS; DISEASE MODELS, ANIMAL; DOGS; GENE EXPRESSION; GENE EXPRESSION REGULATION, VIRAL; INFLUENZA A VIRUS, H7N1 SUBTYPE; INFLUENZA IN BIRDS; MADIN DARBY CANINE KIDNEY CELLS; RNA REPLICASE; RNA-BINDING MOTIFS; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 85044535162     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/s12985-018-0960-4     Document Type: Article

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