Hallmarks of Alzheimer disease are evolving relentlessly in Metropolitan Mexico City infants, children and young adults. APOE4 carriers have higher suicide risk and higher odds of reaching NFT stage V at ≤ 40 years of age

Environmental Research

Volumn 164, Issue , 2018, Pages 475-487

  Calderón Garcidueñas, Lilian ^a,b   Gónzalez Maciel, Angélica ^c   Reynoso Robles, Rafael ^c   Delgado Chávez, Ricardo ^b   Mukherjee, Partha S ^d   Kulesza, Randy J ^e   Torres Jardón, Ricardo ^f   Ávila Ramírez, José ^g   Villarreal Ríos, Rodolfo ^h  

^a UNIVERSITY OF MONTANA   (United States)

^b UNIVERSIDAD DEL VALLE DE MÉXICO   (Mexico)

^c INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^d BOISE STATE UNIVERSITY   (United States)

^e LAKE ERIE COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^f UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^g Grupo Medica Sur   (Mexico)

^h Universidad Autónoma de Piedras Negras   (Mexico)

Author keywords

Alzheimer; Amyloid plaques; APOE4; Brainstem; Children; Combustion derived nanoparticles; Hyperphosphorilated tau; Mexico City; PM2.5; Suicide; Tauopathies; Young adults

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[17-24]; APOLIPOPROTEIN E4; NANOPARTICLE; PROTEIN AGGREGATE; TAU PROTEIN; UNCLASSIFIED DRUG;

BRAIN; CHILD HEALTH; HEALTH IMPACT; HISTOPATHOLOGY; MENTAL DISORDER; METROPOLITAN AREA; NANOPARTICLE; OZONE; PARTICULATE MATTER; PROTEIN; PUBLIC HEALTH; SUICIDE;

ADULT; AGE; AIR POLLUTION; ALLELE; ALZHEIMER DISEASE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN STEM; CAUSE OF DEATH; CHILD; COMBUSTION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MEXICO CITY; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STAGING; SUBCORTEX; SUBSTANTIA NIGRA; SUICIDE; ULTRASTRUCTURE; URBAN POPULATION; YOUNG ADULT; CITY; METABOLISM; MEXICO; PATHOLOGY; PATHOPHYSIOLOGY; PRESCHOOL CHILD;

FEDERAL DISTRICT [MEXICO]; MEXICO CITY; MEXICO [NORTH AMERICA];

ADULT; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEIN E4; CHILD; CHILD, PRESCHOOL; CITIES; HUMANS; INFANT; MEXICO; NEUROFIBRILLARY TANGLES; SUICIDE; YOUNG ADULT;

EID: 85044456540     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2018.03.023     Document Type: Article

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