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Volumn 13, Issue 10, 2016, Pages 1178-1197

The brainstem tau cytoskeletal pathology of Alzheimer’s disease: A brief historical overview and description of its anatomical distribution pattern, evolutional features, pathogenetic and clinical relevance

Author keywords

Alzheimer s disease; Brainstem; Cytoskeletal pathology; Pathoanatomy; Tau

Indexed keywords

CYTOSKELETON PROTEIN; TAU PROTEIN;

EID: 84986907061     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/1567205013666160606100509     Document Type: Review
Times cited : (65)

References (85)
  • 2
    • 33750510024 scopus 로고    scopus 로고
    • Alzheimer 100--highlights in the history of Alzheimer research
    • Jellinger KA. Alzheimer 100--highlights in the history of Alzheimer research. J Neural Transm 113: 1603-23 (2006).
    • (2006) J Neural Transm , vol.113 , pp. 1603-1623
    • Jellinger, K.A.1
  • 4
    • 84918557694 scopus 로고    scopus 로고
    • Neuroanatomy and pathology of sporadic Alzheimer's disease
    • Braak H, Del Trecidi K. Neuroanatomy and pathology of sporadic Alzheimer's disease. Adv Anat Embryol Cell Biol 215: 1-162 (2015).
    • (2015) Adv Anat Embryol Cell Biol , vol.215 , pp. 1-162
    • Braak, H.1    Del Trecidi, K.2
  • 5
    • 84940200391 scopus 로고    scopus 로고
    • Precortical phases of Alzheimer’s disease (AD)-related tau cytoskeletal pathology
    • Stratmann K, Heinsen H, Korf HW, Del Turco D, Seidel, K, Bouzrou M et al. Precortical phases of Alzheimer’s disease (AD)-related tau cytoskeletal pathology. Brain Pathol 26: 371-86 (2016).
    • (2016) Brain Pathol , vol.26 , pp. 371-386
    • Stratmann, K.1    Heinsen, H.2    Korf, H.W.3    Del Turco, D.4    Seidel, K.5    Bouzrou, M.6
  • 6
    • 33947101532 scopus 로고    scopus 로고
    • A brief history of tau: The evolving view of the microtubule-associated protein tau in neurodegenerative diseases
    • Lace GL, Wharton SB, Ince PG. A brief history of tau: the evolving view of the microtubule-associated protein tau in neurodegenerative diseases. Clin Neuropathol 26: 43-58 (2007).
    • (2007) Clin Neuropathol , vol.26 , pp. 43-58
    • Lace, G.L.1    Wharton, S.B.2    Ince, P.G.3
  • 8
    • 0023473468 scopus 로고
    • Axonal and transneuronal transport in the transmission of neurological disease: Potential role in system degenerations, including Alzheimer's disease
    • Saper CB, Wainer BH, German DC. Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease. Neuroscience 23: 389-98 (1987).
    • (1987) Neuroscience , vol.23 , pp. 389-398
    • Saper, C.B.1    Wainer, B.H.2    German, D.C.3
  • 9
    • 0242334029 scopus 로고    scopus 로고
    • Dysphagia and aspiration pneumonia in patients with Alzheimer's disease
    • Kalia M. Dysphagia and aspiration pneumonia in patients with Alzheimer's disease. Metabolism 52: 36-8 (2003).
    • (2003) Metabolism , vol.52 , pp. 36-38
    • Kalia, M.1
  • 10
    • 0023247155 scopus 로고
    • Alzheimer's disease: Neurofibrillary tangles in nuclei that project to the cerebral cortex
    • German DC, White CL, III, Sparkman DR. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience 21: 305-12 (1987).
    • (1987) Neuroscience , vol.21 , pp. 305-312
    • German, D.C.1    White, C.L.2    Sparkman, D.R.3
  • 11
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimerrelated changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimerrelated changes. Acta Neuropathol 8: 239-59 (1991).
    • (1991) Acta Neuropathol , vol.8 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 12
    • 0030680922 scopus 로고    scopus 로고
    • Diagnosis and staging of Alzheimer disease
    • Duyckaerts C, Hauw JJ. Diagnosis and staging of Alzheimer disease. Neurobiol Aging 18: S33-S42 (1997).
    • (1997) Neurobiol Aging , vol.18 , pp. S33-S42
    • Duyckaerts, C.1    Hauw, J.J.2
  • 13
    • 0036047004 scopus 로고    scopus 로고
    • Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease
    • Terwel D, Dewachter I, Van LF. Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease. Neuromol Med 2: 151-65 (2002).
    • (2002) Neuromol Med , vol.2 , pp. 151-165
    • Terwel, D.1    Dewachter, I.2    Van, L.F.3
  • 14
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 112: 389-404 (2006).
    • (2006) Acta Neuropathol , vol.112 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 15
    • 84880187571 scopus 로고    scopus 로고
    • Tau protein, the paired helical filament and Alzheimer's disease
    • Goedert M, Klug A, Crowther RA. Tau protein, the paired helical filament and Alzheimer's disease. J Alzheimers Dis 9: 195-207 (2006).
    • (2006) J Alzheimers Dis , vol.9 , pp. 195-207
    • Goedert, M.1    Klug, A.2    Crowther, R.A.3
  • 16
    • 47549094635 scopus 로고    scopus 로고
    • Staging of neurofibrillary pathology in Alzheimer's dis ease: A study of the BrainNet Europe Consortium
    • Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H et al. Staging of neurofibrillary pathology in Alzheimer's dis ease: a study of the BrainNet Europe Consortium. Brain Pathol 18: 484-96 (2008).
    • (2008) Brain Pathol , vol.18 , pp. 484-496
    • Alafuzoff, I.1    Arzberger, T.2    Al-Sarraj, S.3    Bodi, I.4    Bogdanovic, N.5    Braak, H.6
  • 17
    • 48749090279 scopus 로고    scopus 로고
    • Mechanism of tauinduced neurodegeneration in Alzheimer disease and related tauopathies
    • Alonso AC, Li B, Grundke-Iqbal I, Iqbal K. Mechanism of tauinduced neurodegeneration in Alzheimer disease and related tauopathies. Curr Alzheimer Res 5: 375-84 (2008).
    • (2008) Curr Alzheimer Res , vol.5 , pp. 375-384
    • Alonso, A.C.1    Li, B.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 18
    • 41149156856 scopus 로고    scopus 로고
    • Alzheimer neurofibrillary degeneration: Significance, etiopathogenesis, therapeutics and prevention
    • Iqbal K, Grundke-Iqbal I. Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention. J Cell Mol Med 12: 38-55 (2008).
    • (2008) J Cell Mol Med , vol.12 , pp. 38-55
    • Iqbal, K.1    Grundke-Iqbal, I.2
  • 19
    • 67349143998 scopus 로고    scopus 로고
    • Classification and basic pathology of Alzheimer disease
    • Duyckaerts C, Delatour B, Potier MC. Classification and basic pathology of Alzheimer disease. Acta Neuropathol 118: 5-36 (2009).
    • (2009) Acta Neuropathol , vol.118 , pp. 5-36
    • Duyckaerts, C.1    Delatour, B.2    Potier, M.C.3
  • 22
    • 84874853965 scopus 로고    scopus 로고
    • Mechanisms of protein seeding in neurodegenerative diseases
    • Walker LC, Diamond MI, Duff KE, Hyman BT. Mechanisms of protein seeding in neurodegenerative diseases. Arch Neurol 70: 304-10 (2013).
    • (2013) Arch Neurol , vol.70 , pp. 304-310
    • Walker, L.C.1    Diamond, M.I.2    Duff, K.E.3    Hyman, B.T.4
  • 23
    • 0028362458 scopus 로고
    • A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
    • Braak E, Braak H, Mandelkow EM. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 87: 554-67 (1994).
    • (1994) Acta Neuropathol , vol.87 , pp. 554-567
    • Braak, E.1    Braak, H.2    Mandelkow, E.M.3
  • 24
    • 67649945522 scopus 로고    scopus 로고
    • The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?
    • Grinberg LT, Rub U, Ferretti RE, Nitrini R, Farfel JM, Polichiso L, et al. The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset? Neuropathol Appl Neurobiol 35: 406-16 (2009).
    • (2009) Neuropathol Appl Neurobiol , vol.35 , pp. 406-416
    • Grinberg, L.T.1    Rub, U.2    Ferretti, R.E.3    Nitrini, R.4    Farfel, J.M.5    Polichiso, L.6
  • 26
    • 77954385676 scopus 로고    scopus 로고
    • The propagation of prion-like protein inclusions in neurodegenerative diseases
    • Goedert M, Clavaguera F, Tolnay M. The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends Neurosci 33: 317-25 (2010).
    • (2010) Trends Neurosci , vol.33 , pp. 317-325
    • Goedert, M.1    Clavaguera, F.2    Tolnay, M.3
  • 27
    • 80054024011 scopus 로고    scopus 로고
    • Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders
    • Jucker M, Walker LC. Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders. Ann Neurol 70: 532-40 (2011).
    • (2011) Ann Neurol , vol.70 , pp. 532-540
    • Jucker, M.1    Walker, L.C.2
  • 28
    • 0030823304 scopus 로고    scopus 로고
    • Prevalence, incidence and duration of Braak's stages in the general population: Can we know?
    • Duyckaerts C, Hauw JJ. Prevalence, incidence and duration of Braak's stages in the general population: can we know? Neurobiol Aging 18: 362-9 (1997).
    • (1997) Neurobiol Aging , vol.18 , pp. 362-369
    • Duyckaerts, C.1    Hauw, J.J.2
  • 29
    • 0014720197 scopus 로고
    • Uber die Kerngebiete des menschlichen Hirnstammes. II
    • Braak H. Uber die Kerngebiete des menschlichen Hirnstammes. II. Die Raphekerne. Z Zellforsch 107: 123-41 (1970).
    • (1970) Die Raphekerne. Z Zellforsch , vol.107 , pp. 123-141
    • Braak, H.1
  • 31
    • 0020264291 scopus 로고
    • Correspondence of melanin-pigmented neurons in human brain with A1-A14 catecholamine cell groups
    • Saper CB, Petito CK. Correspondence of melanin-pigmented neurons in human brain with A1-A14 catecholamine cell groups. Brain 105: 87-101 (1982).
    • (1982) Brain , vol.105 , pp. 87-101
    • Saper, C.B.1    Petito, C.K.2
  • 32
    • 0024208497 scopus 로고
    • The pigmented subpeduncular nucleus: A neuromelanin-containing nucleus in the human pontine tegmentum. Morphology and changes in Alzheimer's disease
    • Ohm TG, Braak H. The pigmented subpeduncular nucleus: a neuromelanin-containing nucleus in the human pontine tegmentum. Morphology and changes in Alzheimer's disease. Acta Neuropathol 77: 26-32 (1988).
    • (1988) Acta Neuropathol , vol.77 , pp. 26-32
    • Ohm, T.G.1    Braak, H.2
  • 33
    • 0001377521 scopus 로고
    • Reticular formation of the pons and medulla
    • (Ed: Paxinos G), San Diego: Academic Press
    • Martin GF, Holstege G, amd Mehler WR. Reticular formation of the pons and medulla. In (Ed: Paxinos G). The human central nervous system. San Diego: Academic Press pp. 203-220 (1990).
    • (1990) The Human Central Nervous System , pp. 203-220
    • Martin, G.F.1    Holstege, G.2    Amd Mehler, W.R.3
  • 34
    • 0002668617 scopus 로고
    • Human homologs to brainstem nuclei identified in other animals as revealed by acetylcholinesterase activity
    • (Ed: Paxinos G), San Diego: Academic Press
    • Paxinos G, Tork I, Halliday G, Mehler WR. Human homologs to brainstem nuclei identified in other animals as revealed by acetylcholinesterase activity. In (Ed: Paxinos G). The human central nervous system. San Diego: Academic Press pp. 149-202 (1990).
    • (1990) The Human Central Nervous System , pp. 149-202
    • Paxinos, G.1    Tork, I.2    Halliday, G.3    Mehler, W.R.4
  • 36
    • 0002588708 scopus 로고
    • Cholinergic system
    • Paxinos G, Ed., San Diego: Academic Press
    • Saper CB. Cholinergic system. In: Paxinos G, Ed. The human central nervous system. San Diego: Academic Press pp. 1095-1113 (1990).
    • (1990) The Human Central Nervous System , pp. 1095-1113
    • Saper, C.B.1
  • 37
    • 0000128250 scopus 로고
    • Raphe nuclei and the serotoninergic system
    • Paxinos G, Ed., San Diego: Academic Press
    • Tork I, Hornung JP. Raphe nuclei and the serotoninergic system. In: Paxinos G, Ed. The human central nervous system. San Diego: Academic Press pp. 1001-1022 (1990).
    • (1990) The Human Central Nervous System , pp. 1001-1022
    • Tork, I.1    Hornung, J.P.2
  • 39
    • 0026320767 scopus 로고
    • Awakening the sleeping giant: Anatomy and plasticity of the brain serotoninergic system
    • Azmitia EC, Whitaker-Azmitia PM. Awakening the sleeping giant: anatomy and plasticity of the brain serotoninergic system. J Clin Psychiatry 52 (Suppl.): 4-16 (1991).
    • (1991) J Clin Psychiatry , vol.52 , pp. 4-16
    • Azmitia, E.C.1    Whitaker-Azmitia, P.M.2
  • 40
    • 0029080281 scopus 로고
    • Human intermediate reticular zone: A cytoand chemoarchitectonic study
    • Huang XF, Paxinos G. Human intermediate reticular zone: A cytoand chemoarchitectonic study. J Comp Neurol 360: 571-88 (1995).
    • (1995) J Comp Neurol , vol.360 , pp. 571-588
    • Huang, X.F.1    Paxinos, G.2
  • 41
    • 0030067963 scopus 로고    scopus 로고
    • Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans
    • McRitchie DA, Hardman CD, Halliday GM. Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans. J Comp Neurol 364: 121-50 (1996).
    • (1996) J Comp Neurol , vol.364 , pp. 121-150
    • McRitchie, D.A.1    Hardman, C.D.2    Halliday, G.M.3
  • 42
    • 0034925264 scopus 로고    scopus 로고
    • The autonomic higher order processing nuclei of the lower brain stem are among the early targets of the Alzheimer's disease-related cytoskeletal pathology
    • Rub U, Del Tredici, Schultz C, Thal DR, Braak E, Braak H. The autonomic higher order processing nuclei of the lower brain stem are among the early targets of the Alzheimer's disease-related cytoskeletal pathology. Acta Neuropathol 101: 555-64 (2001).
    • (2001) Acta Neuropathol , vol.101 , pp. 555-564
    • Rub, U.1    Tredici, D.2    Schultz, C.3    Thal, D.R.4    Braak, E.5    Braak, H.6
  • 43
    • 17044447789 scopus 로고    scopus 로고
    • Anatomically based guidelines for systematic investigation of the central somatosensory system and their application to a spinocerebellar ataxia type 2 (SCA2) patient
    • Rub U, Schultz C, Del Tredici K, Gierga K, Reifenberger G, de Vos RA, et al. Anatomically based guidelines for systematic investigation of the central somatosensory system and their application to a spinocerebellar ataxia type 2 (SCA2) patient. Neuropathol Appl Neurobiol 29: 418-33 (2003).
    • (2003) Neuropathol Appl Neurobiol , vol.29 , pp. 418-433
    • Rub, U.1    Schultz, C.2    Del Tredici, K.3    Gierga, K.4    Reifenberger, G.5    De Vos, R.A.6
  • 44
    • 0346023036 scopus 로고    scopus 로고
    • The human raphe nuclei and the serotonergic system
    • Hornung JP. The human raphe nuclei and the serotonergic system. J Chem Neuroanatomy 26: 331-43 (2003).
    • (2003) J Chem Neuroanatomy , vol.26 , pp. 331-343
    • Hornung, J.P.1
  • 45
    • 4344644922 scopus 로고    scopus 로고
    • Degeneration of the central vestibular system in spinocerebellar ataxia type 3 (SCA3) patients and its possible clinical significance
    • Rub U, Brunt ER, de Vos RA, Del Turco D, Del Tredici K, Gierga K, et al. Degeneration of the central vestibular system in spinocerebellar ataxia type 3 (SCA3) patients and its possible clinical significance. Neuropathol Appl Neurobiol 30: 402-14 (2004).
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 402-414
    • Rub, U.1    Brunt, E.R.2    De Vos, R.A.3    Del Turco, D.4    Del Tredici, K.5    Gierga, K.6
  • 46
    • 27144467422 scopus 로고    scopus 로고
    • Spinocerebellar ataxias types 2 and 3: Degeneration of the precerebellar nuclei isolates the three phylogenetically defined regions of the cerebellum
    • Rub U, Gierga K, Brunt ER, de Vos RA, Bauer M, Schols L, et al. Spinocerebellar ataxias types 2 and 3: degeneration of the precerebellar nuclei isolates the three phylogenetically defined regions of the cerebellum. J Neural Transm 112: 1523-45 (2005).
    • (2005) J Neural Transm , vol.112 , pp. 1523-1545
    • Rub, U.1    Gierga, K.2    Brunt, E.R.3    De Vos, R.A.4    Bauer, M.5    Schols, L.6
  • 48
    • 52949135556 scopus 로고    scopus 로고
    • Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7)
    • Hoche F, Seidel K, Brunt ER, Auburger G, Schols L, Burk K, et al. Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7). Neuropathol Appl Neurobiol 34: 479-91 (2008).
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 479-491
    • Hoche, F.1    Seidel, K.2    Brunt, E.R.3    Auburger, G.4    Schols, L.5    Burk, K.6
  • 49
    • 42649086767 scopus 로고    scopus 로고
    • Functional neuroanatomy of the human premotor oculomotor brainstem nuclei: Insights from postmortem and advanced in vivo imaging studies
    • Rub U, Jen JC, Braak H, Deller T. Functional neuroanatomy of the human premotor oculomotor brainstem nuclei: insights from postmortem and advanced in vivo imaging studies. Exp Brain Res 187: 167-80 (2008).
    • (2008) Exp Brain Res , vol.187 , pp. 167-180
    • Rub, U.1    Jen, J.C.2    Braak, H.3    Deller, T.4
  • 50
    • 0032921667 scopus 로고    scopus 로고
    • Focal pathology in the Edinger-Westphal nucleus explains pupillary hypersensitivity in Alzheimer's disease
    • Scinto LF, Wu CK, Firla KM, Daffner KR, Saroff D, Geula C. Focal pathology in the Edinger-Westphal nucleus explains pupillary hypersensitivity in Alzheimer's disease. Acta Neuropatholog 97: 557-64 (1999).
    • (1999) Acta Neuropatholog , vol.97 , pp. 557-564
    • Scinto, L.F.1    Wu, C.K.2    Firla, K.M.3    Daffner, K.R.4    Saroff, D.5    Geula, C.6
  • 51
    • 0034995849 scopus 로고    scopus 로고
    • The premotor region essential for rapid vertical eye movements shows early involvement in Alzheimer's disease-related cytoskeletal pathology
    • Rub U, Del Tredici K, Schultz C, Buttner-Ennever JA, Braak H. The premotor region essential for rapid vertical eye movements shows early involvement in Alzheimer's disease-related cytoskeletal pathology. Vision Res 41: 2149-56 (2001).
    • (2001) Vision Res , vol.41 , pp. 2149-2156
    • Rub, U.1    Del Tredici, K.2    Schultz, C.3    Buttner-Ennever, J.A.4    Braak, H.5
  • 52
    • 0035958568 scopus 로고    scopus 로고
    • Early involvement of the tegmentopontine reticular nucleus during the evolution of Alzheimer's disease-related cytoskeletal pathology
    • Rub U, Schultz C, Del Tredici K, Braak H. Early involvement of the tegmentopontine reticular nucleus during the evolution of Alzheimer's disease-related cytoskeletal pathology. Brain Res 908: 107-12 (2001).
    • (2001) Brain Res , vol.908 , pp. 107-112
    • Rub, U.1    Schultz, C.2    Del Tredici, K.3    Braak, H.4
  • 53
    • 0035160073 scopus 로고    scopus 로고
    • Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer's patients
    • Scinto LF, Frosch M, Wu CK, Daffner KR, Gedi N, Geula C. Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer's patients. Neurobiol Aging 22: 729-36 (2001).
    • (2001) Neurobiol Aging , vol.22 , pp. 729-736
    • Scinto, L.F.1    Frosch, M.2    Wu, C.K.3    Daffner, K.R.4    Gedi, N.5    Geula, C.6
  • 54
    • 0024820792 scopus 로고
    • Is Alzheimer's disease an anterograde degeneration, originating in the brainstem, and disrupting metabolic and functional interactions between neurons and glial cells?
    • Hertz L. Is Alzheimer's disease an anterograde degeneration, originating in the brainstem, and disrupting metabolic and functional interactions between neurons and glial cells? Brain Res Brain Res Rev 14: 335-53 (1989).
    • (1989) Brain Res Brain Res Rev , vol.14 , pp. 335-353
    • Hertz, L.1
  • 56
    • 0016817278 scopus 로고
    • Distribution of Alzheimer's neurofibrillary tangles in the basal ganglia and brain stem of progressive supranuclear palsy and Alzheimer's disease
    • Ishino H, Otsuki S. Distribution of Alzheimer's neurofibrillary tangles in the basal ganglia and brain stem of progressive supranuclear palsy and Alzheimer's disease. Folia Psychiatr Neurol 29: 179-87 (1975).
    • (1975) Folia Psychiatr Neurol , vol.29 , pp. 179-187
    • Ishino, H.1    Otsuki, S.2
  • 58
    • 0021139170 scopus 로고
    • Nucleus raphe dorsalis in dementia of the Alzheimer type: Neurofibrillary changes and neuronal packing density
    • Curcio CA, Kemper T. Nucleus raphe dorsalis in dementia of the Alzheimer type: neurofibrillary changes and neuronal packing density. J Neuropathol Exp Neurol 43: 359-68 (1984).
    • (1984) J Neuropathol Exp Neurol , vol.43 , pp. 359-368
    • Curcio, C.A.1    Kemper, T.2
  • 59
    • 0022414019 scopus 로고
    • The rostral mesencephalon in Parkinson's disease and Alzheimer's disease
    • Hunter S. The rostral mesencephalon in Parkinson's disease and Alzheimer's disease. Acta Neuropathol 68: 53-8 (1985).
    • (1985) Acta Neuropathol , vol.68 , pp. 53-58
    • Hunter, S.1
  • 60
    • 0022397142 scopus 로고
    • A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease
    • Tabaton M, Schenone A, Romagnoli P, Mancardi GL. A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease. Acta Neuropathol 68: 218-23 (1985).
    • (1985) Acta Neuropathol , vol.68 , pp. 218-223
    • Tabaton, M.1    Schenone, A.2    Romagnoli, P.3    Mancardi, G.L.4
  • 61
    • 0021801018 scopus 로고
    • Nucleus raphe dorsalis in Alzheimer's disease: Neurofibrillary tangles and loss of large neurons
    • Yamamoto T, Hirano A. Nucleus raphe dorsalis in Alzheimer's disease: neurofibrillary tangles and loss of large neurons. Ann Neurol 17: 573-7 (1985).
    • (1985) Ann Neurol , vol.17 , pp. 573-577
    • Yamamoto, T.1    Hirano, A.2
  • 63
    • 0023124285 scopus 로고
    • Dopaminergic neurotransmitter systems in Alzheimer's disease and in Down's syndrome at middle age
    • Mann DM, Yates PO, Marcyniuk B. Dopaminergic neurotransmitter systems in Alzheimer's disease and in Down's syndrome at middle age. J Neurol Neurosurg Psychiatry 50: 341-4 (1987).
    • (1987) J Neurol Neurosurg Psychiatry , vol.50 , pp. 341-344
    • Mann, D.M.1    Yates, P.O.2    Marcyniuk, B.3
  • 64
    • 0023941502 scopus 로고
    • The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's disease
    • Jellinger K. The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's disease. J Neurol Neurosurg Psychiatry 51: 540-3 (1988).
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 540-543
    • Jellinger, K.1
  • 65
    • 0023822661 scopus 로고
    • Neurofibrillary tangles in cholinergic pedunculopontine neurons in Alzheimer's disease
    • Mufson EJ, Mash DC, Hersh LB. Neurofibrillary tangles in cholinergic pedunculopontine neurons in Alzheimer's disease. Ann Neurol 24: 623-9 (1988).
    • (1988) Ann Neurol , vol.24 , pp. 623-629
    • Mufson, E.J.1    Mash, D.C.2    Hersh, L.B.3
  • 67
    • 0024804051 scopus 로고
    • Neurofibrillary degeneration and neuronal loss in Alzheimer's disease
    • Bondareff W, Mountjoy CQ, Roth M, Hauser DL. Neurofibrillary degeneration and neuronal loss in Alzheimer's disease. Neurobiol Aging 10: 709-15 (1989).
    • (1989) Neurobiol Aging , vol.10 , pp. 709-715
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3    Hauser, D.L.4
  • 68
    • 0024578765 scopus 로고
    • The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome
    • Gibb WR, Mountjoy CQ, Mann DM, Lees AJ. The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome. J Neurol Neurosurg Psychiatry 52: 193-200 (1989).
    • (1989) J Neurol Neurosurg Psychiatry , vol.52 , pp. 193-200
    • Gibb, W.R.1    Mountjoy, C.Q.2    Mann, D.M.3    Lees, A.J.4
  • 69
    • 0024495708 scopus 로고
    • Auditory brainstem nuclei in Alzheimer's disease
    • Ohm TG, Braak H. Auditory brainstem nuclei in Alzheimer's disease. Neurosci Lett 96: 60-3 (1989).
    • (1989) Neurosci Lett , vol.96 , pp. 60-63
    • Ohm, T.G.1    Braak, H.2
  • 70
    • 0026485096 scopus 로고
    • Brain stem serotonin-synthesizing neurons in Alzheimer's disease: A clinicopathological correlation
    • Halliday GM, McCann HL, Pamphlett R, Brooks WS, Creasey H, McCusker E, et al. Brain stem serotonin-synthesizing neurons in Alzheimer's disease: a clinicopathological correlation. Acta Neuropathol 84: 638-50 (1992).
    • (1992) Acta Neuropathol , vol.84 , pp. 638-650
    • Halliday, G.M.1    McCann, H.L.2    Pamphlett, R.3    Brooks, W.S.4    Creasey, H.5    McCusker, E.6
  • 71
    • 0026508908 scopus 로고
    • Selective loss of nigral neurons in Alzheimer's disease: A morphometric study
    • Uchihara T, Kondo H, Kosaka K, Tsukagoshi H. Selective loss of nigral neurons in Alzheimer's disease: a morphometric study. Acta Neuropathol 83: 271-6 (1992).
    • (1992) Acta Neuropathol , vol.83 , pp. 271-276
    • Uchihara, T.1    Kondo, H.2    Kosaka, K.3    Tsukagoshi, H.4
  • 72
    • 0029572480 scopus 로고
    • Localisation and association of pathomorphological changes at the brainstem in Alzheimer's disease
    • Giess R, Schlote W. Localisation and association of pathomorphological changes at the brainstem in Alzheimer's disease. Mech Ageing Dev 84: 209-26 (1995).
    • (1995) Mech Ageing Dev , vol.84 , pp. 209-226
    • Giess, R.1    Schlote, W.2
  • 73
    • 0033848471 scopus 로고    scopus 로고
    • Selective pathological changes of the periaqueductal gray matter in Alzheimer's disease
    • Parvizi J, Van Hoesen GW, Damasio A. Selective pathological changes of the periaqueductal gray matter in Alzheimer's disease. Ann Neurol 48: 344-53 (2000).
    • (2000) Ann Neurol , vol.48 , pp. 344-353
    • Parvizi, J.1    Van Hoesen, G.W.2    Damasio, A.3
  • 74
    • 0035117748 scopus 로고    scopus 로고
    • The selective vulnerability of brainstem nuclei to Alzheimer's disease
    • Parvizi J, Van Hoesen GW, Damasio A. The selective vulnerability of brainstem nuclei to Alzheimer's disease. Ann Neurol 49: 53-66 (2001).
    • (2001) Ann Neurol , vol.49 , pp. 53-66
    • Parvizi, J.1    Van Hoesen, G.W.2    Damasio, A.3
  • 75
    • 2942565912 scopus 로고    scopus 로고
    • Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression
    • Hendricksen M, Thomas AJ, Ferrier IN, Ince P, O'Brien JT. Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression. Am J Psychiatry 161: 1096-102 (2004).
    • (2004) Am J Psychiatry , vol.161 , pp. 1096-1102
    • Hendricksen, M.1    Thomas, A.J.2    Ferrier, I.N.3    Ince, P.4    O'brien, J.T.5
  • 76
    • 17644392127 scopus 로고    scopus 로고
    • The pathology of the substantia nigra in Alzheimer disease with extrapyramidal signs
    • Burns JM, Galvin JE, Roe CM, Morris JC, McKeel DW. The pathology of the substantia nigra in Alzheimer disease with extrapyramidal signs. Neurology 64: 1397-1403 (2005).
    • (2005) Neurology , vol.64 , pp. 1397-1403
    • Burns, J.M.1    Galvin, J.E.2    Roe, C.M.3    Morris, J.C.4    McKeel, D.W.5
  • 77
    • 80054904670 scopus 로고    scopus 로고
    • Stages of the pathologic process in Alzheimer disease: Age categories from 1 to 100 years
    • Braak H, Thal DR, Ghebremedhin E, Del Tredici. Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years. J Neuropathol Exp Neurol 70: 960-9 (2011).
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 960-969
    • Braak, H.1    Thal, D.R.2    Ghebremedhin, E.3    Tredici, D.4
  • 78
    • 0018880805 scopus 로고
    • Subcortical afferents to the hippocampal formation in the monkey
    • Amaral DG, Cowan WM. Subcortical afferents to the hippocampal formation in the monkey. J Comp Neurol 189: 573-91 (1980).
    • (1980) J Comp Neurol , vol.189 , pp. 573-591
    • Amaral, D.G.1    Cowan, W.M.2
  • 79
    • 0021067734 scopus 로고
    • Brainstem connections to the Edinger-Westphal nucleus of the cat: A retrograde tracer study
    • Breen LA, Burde RM, Loewy AD. Brainstem connections to the Edinger-Westphal nucleus of the cat: a retrograde tracer study. Brain Res 261: 303-6 (1983).
    • (1983) Brain Res , vol.261 , pp. 303-306
    • Breen, L.A.1    Burde, R.M.2    Loewy, A.D.3
  • 80
    • 0023784453 scopus 로고
    • Ascending and descending projections of the nucleus reticularis gigantocellularis in the cat demonstrated by the anterograde neural tracer, Phaseolus vulgaris leucoagglutinin (PHA-L)
    • Matsuyama K, Ohta Y, Mori S. Ascending and descending projections of the nucleus reticularis gigantocellularis in the cat demonstrated by the anterograde neural tracer, Phaseolus vulgaris leucoagglutinin (PHA-L). Brain Res 460: 124-41 (1988).
    • (1988) Brain Res , vol.460 , pp. 124-141
    • Matsuyama, K.1    Ohta, Y.2    Mori, S.3
  • 81
    • 0022631613 scopus 로고
    • Anatomical studies on the nucleus reticularis tegmenti pontis in the pigmented rat. I. Cytoarchitecture, topography, and cerebral cortical afferents
    • Torigoe Y, Blanks RH, Precht W. Anatomical studies on the nucleus reticularis tegmenti pontis in the pigmented rat. I. Cytoarchitecture, topography, and cerebral cortical afferents. J Comp Neurol 243: 71-87 (1986).
    • (1986) J Comp Neurol , vol.243 , pp. 71-87
    • Torigoe, Y.1    Blanks, R.H.2    Precht, W.3
  • 82
    • 0035726836 scopus 로고    scopus 로고
    • Cortical and subcortical afferents to the nucleus reticularis tegmenti pontis and basal pontine nuclei in the macaque monkey
    • Giolli RA, Gregory KM, Suzuki DA, Blanks RH, Lui F, Betelak KF. Cortical and subcortical afferents to the nucleus reticularis tegmenti pontis and basal pontine nuclei in the macaque monkey. Vis Neurosci 18: 725-40 (2001).
    • (2001) Vis Neurosci , vol.18 , pp. 725-740
    • Giolli, R.A.1    Gregory, K.M.2    Suzuki, D.A.3    Blanks, R.H.4    Lui, F.5    Betelak, K.F.6
  • 83
    • 0036167359 scopus 로고    scopus 로고
    • Neural pathways underlying vocal control
    • Jurgens U. Neural pathways underlying vocal control. Neurosci Biobehav Rev 26: 235-258 (2002)
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 235-258
    • Jurgens, U.1
  • 84
    • 79954588304 scopus 로고    scopus 로고
    • The Edinger-Westphal nucleus: A historical, structural, and functional perspective on a dichotomous terminology
    • Kozicz T, Bittencourt JC, May PJ, Reiner A, Gamlin PD, Palkovits M, et al. The Edinger-Westphal nucleus: a historical, structural, and functional perspective on a dichotomous terminology. J Comp Neurol 519: 1413-34 (2011).
    • (2011) J Comp Neurol , vol.519 , pp. 1413-1434
    • Kozicz, T.1    Bittencourt, J.C.2    May, P.J.3    Reiner, A.4    Gamlin, P.D.5    Palkovits, M.6
  • 85
    • 0342657004 scopus 로고    scopus 로고
    • Parkinson's disease: Affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system
    • Braak H, Rub U, Sandmann-Keil D, Gai WP, de Vos RA, Jansen Steur EN. Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system. Acta Neuropathol 99: 489-95 (2000).
    • (2000) Acta Neuropathol , vol.99 , pp. 489-495
    • Braak, H.1    Rub, U.2    Sandmann-Keil, D.3    Gai, W.P.4    De Vos, R.A.5    Jansen Steur, E.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.