Uncovering the mechanisms of Chinese herbal medicine (MaZiRenWan) for functional constipation by focused network pharmacology approach

Frontiers in Pharmacology

Volumn 9, Issue MAR, 2018, Pages

  Huang, Tao ^a   Ning, Ziwan ^a   Hu, Dongdong ^a,b,c   Zhang, Man ^a,d   Zhao, Ling ^a   Lin, Chengyuan ^a,e   Zhong, Linda L D ^a,f   Yang, Zhijun ^a   Xu, Hongxi ^b,c   Bian, Zhaoxiang ^a,f  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery   (China)

^d GUANGZHOU MEDICAL UNIVERSITY   (China)

^e YUNNAN MINZU UNIVERSITY   (China)

^f HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Chinese Herbal Medicine; Component group; Focused network pharmacology; Functional constipation; MaZiRenWan; Representative compound

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE A1 RECEPTOR; ALBIFLORIN; AMYGDALIN; AROMATASE; AURANTIIN; CANNABINOID 1 RECEPTOR; CHINESE DRUG; EMODIN; ESTROGEN RECEPTOR BETA; HERBACEOUS AGENT; HONOKIOL; MAZIRENWAN; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CHINESE MEDICINE; COLON MOTILITY; COLONIC MUSCLE; CONSTIPATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG STRUCTURE; FECES ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CONTRACTION; MALE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 85044306983     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2018.00270     Document Type: Article

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