Evaluation of the pharmacokinetics and renal excretion of Ma-Zi-Ren-Wan in health subjects

World Journal of Traditional Chinese Medicine

Volumn 3, Issue 2, 2017, Pages 8-15

  Hu, Dong Dong ^a   Zhong, Linda ^a   Wai, Kun ^a   Mu, Huai Xue ^a   Lin, Cheng Yuan ^a   Zhao, Ling ^a   Dai, Liang ^a   Huang, Tao ^a   Bian, Zhao Xiang ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Human plasma; LC MS MS; Ma Zi Ren Wan; Pharmacokinetics; Renal Excretion

Indexed keywords

EID: 85044263481     PISSN: 23118571     EISSN: 25892894     Source Type: Journal    
DOI: 10.15806/j.issn.2311-8571.2016.0050     Document Type: Article

References (35)

1. Eoff J, Lembo AJ. Optimal treatment of chronic constipation in managed care: review and roundtable discussion. J Manag Care Pharm 2008;14(9 Suppl A):1-15.
2. Bharucha AE, Pemberton JH, LOCKE III GR. American Gastroenterological Association technical review on constipation. Gastroenterology 2013;144(1):218.
3. Mostafa R. Rome III: The functional gastrointestinal disorders, 2006, World J Gastroenterol 2008;14(13):2124.
4. Ramkumar D, Rao SS. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review. Am J Gastrointerol 2005;100(4):936-971.
5. Jiang C, Xu Q, Wen X, et al. Current developments in pharmacological therapeutics for chronic constipation. Acta Pharm Sin B 2015; 5(4):300-309.
6. Zhang B, Dong J, Zhou Z. Traditional Chinese internal medicine-Shanghai: Shanghai Scientific and Technical Publishers, 1985.
7. Commission CP. Hemp Seed Pills. Pharmacopeia of the People's Republic of China 2010;1:1093.
8. Bian Z, Cheng C, Zhu L. Chinese herbal medicine for functional constipation: a randomised controlled trial. Hong Kong Med J 2013; 19(Suppl 9):44-46.
9. Cheng CW, Bian ZX, Zhu LX, et al. Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation Am J Gastroenterol 2011;106(1):120-129.
10. Zhou WJ, Song JZ, Fu WW, et al. Chemical comparison of two dosage forms of Hemp Seed Pills by UHPLC-Q-ToF-MS/MS and multivariate statistical techniques. J Pharm Biomed Anal 2013;84:59-68.
11. Gong XH, Li Y, Zhang RQ, et al. The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharma-cokinetics of Rhubarb extract between normal and diseased rats. Eur J Drug Metab Pharmacokinet 2015;40(4):379-388.
12. Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med 2009;75(1):24-31.
13. Chan SS, Zhao M, Lao L, et al. Magnolol and honokiol account for the anti-spasmodic effect of Magnolia officinalis in isolated guinea pig ileum. Planta Med 2008;74(4):381-384.
14. Kausland A. The Treatment of Constipation by Chinese Medicine. Journal Of Chinese Medicine-Hove 1995;17.
15. Lin-Lin C, Yan-Hui W, Jin Q, et al. Identification and determination of absorbed components of Danggui-Shaoyao-San in rat plasma. Chin J Nat Med 2011;9(5):363-368.
16. Feng C, Liu M, Shi X, et al. Pharmacokinetic properties of paeoniflorin, albiflorin and oxypaeoniflorin after oral gavage of extracts of Radix Paeoniae Rubra and Radix Paeoniae Alba in rats. J Ethnopharmacol 2010;130(2):407-413.
17. Gan P, Zhong M, Huang X, et al. Pharmacokinetic comparisons of albiflorin and paeoniflorin after oral administration of Shaoyao-Gancao-Tang and single herb Paeony decoction to rats. Planta Med 2012;78(3):237-243.
18. Jiang F, Zhao Y, Wang J, et al. Comparative pharmacokinetic study of paeoniflorin and albiflorin after oral administration of Radix Paeoniae Rubra in normal rats and the acute cholestasis hepatitis rats. Fitoterapia 2012;83(2):415-421.
19. Sheng Y, Li L, Wang C, et al. Solid-phase extraction-liquid chromato-graphic method for the determination and pharmacokinetic studies of albiflorin and paeoniflorin in rat serum after oral administration of Si-Wu decoction. J Chromatogr B Analyt Technol Biomed Life Sci 2004;806(2):127-132.
20. Tong L, Wan M, Zhou D, et al. LC-MS/MS determination and pharma-cokinetic study of albiflorin and paeoniflorin in rat plasma after oral administration of Radix Paeoniae Alba extract and Tang-Min-Ling-Wan. Biomed Chromatogr 2010;24(12):1324-1331.
21. Wang Q, Yang HY, Liu WN, et al. Determination of albiflorin in rat plasma by LC-MS/MS and its pharmacokinetics. Chinese Pharmaceutical Journal 2008;43(15):16.
22. Xu CH, Wang P, Wang Y, et al. Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: Competing mechanisms between paeoniflorin and glycyrrhetinic acid. J Ethnopharmacol 2013;149(2):443-452.
23. Chen J, Yan X, Kim TJ, et al. Metabolic pharmacokinetics in rats: differences between pure amygdalin and amygdalin in a decoction of peach seeds. Bull Korean Chem Soc 2012;33(5):1470-1474.
24. Li H, Guo H, Wu L, et al. Comparative pharmacokinetics study of three anthraquinones in rat plasma after oral administration of Radix et Rhei Rhizoma extract and Dahuang Fuzi Tang by high performance liquid chromatography-mass spectrometry. J Pharm Biomed Anal 2013;76:215-218.
25. Tong L, Zhou D, Gao J, et al. Simultaneous determination of naringin, hesperidin, neohesperidin, naringenin and hesperetin of Fructus aurantii extract in rat plasma by liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal 2012;58:58-64.
26. Hu DD, Han QB, Zhong LL, et al. Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan. J Chromatogr B Analyt Techno! Biomed Life Sci 2015;1000:136-146.
27. Zhong LL, Kun W, Zhao L, et al. Tolerability, exposure and pharmacokinetics in healthy subjects of a Chinese herbal medicine MaZiRenWan (MZRW): Study protocol for a randomized open-labelled, three-arm phase 0/1 clinical trial. Eur J Integr Med 2016;8(4):581-586.
28. Jiang JY, Yang MW, Qian W, et al. Quantitative determination of rhein in human plasma by liquid chromatography-negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study. J Pharm Biomed Anal 2012;57:19-25.
29. Ojha A, Rathod R, Padh H. Simultaneous HPLC-UV determination of rhein and aceclofenac in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2009;877(11-12):1145-1148.
30. Li X, Shi F, Gu P, et al. A sensitive LC-MS/MS method for simultaneous determination of amygdalin and paeoniflorin in human plasma and its application. J Pharm Biomed Anal 2014;92:160-164.
31. Franken LG, Masman AD, de Winter BC, et al. Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients. Clin Pharmacokinet 2009;55(6): 697-709.
32. Munekage M, Kitagawa H, Ichikawa K, et al. Pharmacokinetics of dai-kenchuto, a traditional Japanese medicine (kampo) after single oral administration to healthy Japanese volunteers. Drug Metab Dispos 2011;39(10):1784-1788.
33. Schmidt MS, King CL, Thomsen EK, et al. Liquid chromatogra-phy-mass spectrometry analysis of diethylcarbamazine in human plasma for clinical pharmacokinetic studies. J Pharm Biomed Anal 2014;98:307-310.
34. Nadella TR, Suryadevara V, Lankapalli SR, et al. LC-MS/MS method development for quantification of busulfan in human plasma and its application in pharmacokinetic study. J Pharm Biomed Anal 2016; 120:168-174.
35. Kallem RR, Jillela B, Ravula AR, et al. Highly sensitive LC-MS/MS-ESI method for determination of phenelzine in human plasma and its application to a human pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 2016;1022:126-132.