Acetylcholinesterase distribution and refractory constipation - A new criterion for diagnosis and management

Pediatric Surgery International

Volumn 18, Issue 5-6, 2002, Pages 349-353

  Kobayashi, Hiroyuki ^a   Li, Zhixin ^a   Yamataka, Atsuyuki ^a   Lane, Geoffrey J ^a   Yokota, Hiroo ^b   Watanabe, Akira ^b   Miyano, Takeshi ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b Hokota General Hospital   (Japan)

Author keywords

Acetylcholinesterase; Constipation; Hirschsprung's disease; Intestinal neuronal dysplasia

Indexed keywords

ACETYLCHOLINESTERASE; ENEMA; LAXATIVE;

ADOLESCENT; ARTICLE; BARIUM ENEMA; CHILD; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; ENZYME ACTIVITY; ENZYME LOCALIZATION; HIRSCHSPRUNG DISEASE; HUMAN; HUMAN TISSUE; INTESTINAL NEURONAL DYSPLASIA; LAMINA PROPRIA; MAJOR CLINICAL STUDY; NEWBORN; PRIORITY JOURNAL; RECTUM BIOPSY; RECTUM MUCOSA; REFRACTORY CONSTIPATION; SUBMUCOSA; TREATMENT OUTCOME; TREATMENT PLANNING; CHRONIC DISEASE; CYTOCHEMISTRY; ENZYMOLOGY; GASTROINTESTINAL MOTILITY; INFANT; METABOLISM; PATHOPHYSIOLOGY; PRESCHOOL CHILD; RECTUM;

ACETYLCHOLINESTERASE; ADOLESCENT; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; CONSTIPATION; GASTROINTESTINAL MOTILITY; HISTOCYTOCHEMISTRY; HUMANS; INFANT; INFANT, NEWBORN; RECTUM;

EID: 0036728477     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-002-0776-5     Document Type: Article

References (14)

1. Athow AC, Filipe MI, Drake DP (1990) Problems and advantages of acetylcholinesterase histochemistry of rectal suction biopsies in the diagnosis of Hirschsprung's disease. J Pediatr Surg 25: 520-526
2. Borchard F, Meier-Ruge WA, Wiebecke B et al (1991) Innervationsstorungen des Dickdarms: Klassifikation und Diagnostik. Pathologe 12: 171-174
3. Cord-Udy CL, Smith VV, Ahmed S, et al (1997) An evaluation of the role of suction rectal biopsy in the diagnosis of intestinal neuronal dysplasia. J Pediatr Gastroenterol Nutr 24: 1-6
4. Donatelle EP (1990) Constipation: pathophysiology and treatment. Am Fam Physician 42: 1335-1342
5. Ghosh A, Griffiths DM (1998) Rectal biopsy in the investigation of constipation. Arch Dis Child 79: 266-268
6. Hirakawa H, Kobayashi H, O'Briain DS et al (1995) Absence of NADPH-diaphorase activity in internal anal sphincter (IAS) achalasia. J Pediatr Gastroenterol Nutr 20: 54-58
7. Koletzko S, Jesch I, Faus-Keßler T, et al (1999) Rectal biopsy for diagnosis of intestinal neuronal dysplasia in children: a prospective multicentre study on interobserver variation and clinical outcome. Gut 44: 853-861
8. Lake BD, Puri P, Nixon HH, et al (1978) Hirschsprung's disease: an appraisal of histochemically demonstrated acetylcholinesterase activity in suction rectal biopsy specimens as an aid to diagnosis. Arch Pathol Lab Med 102: 244-247
9. Leung AKC, Chan PYH, Cho HYH (1996) Constipation in children. Am Fam Physician 54: 611-618
10. Puri P, Wester T (1998) Intestinal neuronal dysplasia. Semin Pediatr Surg 7: 181-186
11. Schmittenbecher PP, Schmidt A, Meier-Ruge W, et al (1995) Rectal suction biopsy: can it be sufficient to diagnose neuronal intestinal dysplasia? Eur J Pediatr Surg 5: 277-279
12. Smith VV (1992) Isolated intestinal neuronal dysplasia: a descriptive histological pattern or a distinct clinicopathological entity. In: Hadziselimovic F, Herzog B (eds) Inflammatory bowel disease and morbus Hirschsprung. Dordrecht, Boston London, Kluwer, pp 203-214
13. Toorman J, Bots GTAM, Vio PMA (1977) Acetylcholinesterase activity in rectal mucosa of children with obstipation. Virchows Arch A Path Anat and Histol 376: 159-164
14. Toyosaka A, Okamoto E, Okasora T, et al (1993) Clinical, laboratory and prognostic features of congenital large intestinal motor dysfunction (pseudo-Hirschsprung's disease). Clin Auton Res 3: 243-248