Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Cell

Volumn 173, Issue 1, 2018, Pages 90-103.e19

  Khajuria, Rajiv K ^a,b,c   Munschauer, Mathias ^b   Ulirsch, Jacob C ^a,b   Fiorini, Claudia ^a,b   Ludwig, Leif S ^a,b   McFarland, Sean K ^a,b   Abdulhay, Nour J ^a,b   Specht, Harrison ^b   Keshishian, Hasmik ^b   Mani, D R ^b   Jovanovic, Marko ^b   Ellis, Steven R ^d   Fulco, Charles P ^b   Engreitz, Jesse M ^b   Schütz, Sabina ^e   Lian, John ^a,f,g   Gripp, Karen W ^h   Weinberg, Olga K ⁱ   Pinkus, Geraldine S ^j   Gehrke, Lee ^a,f,g   Regev, Aviv ^b   Lander, Eric S ^b   Gazda, Hanna T ^a,b   Lee, Winston Y ^j   Panse, Vikram G ^e   Carr, Steven A ^b   Sankaran, Vijay G ^a,b   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF LOUISVILLE   (United States)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f Massachusetts Institute of Technology   (United States)

^g HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^h NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

ⁱ BOSTON CHILDREN S HOSPITAL   (United States)

^j BRIGHAM AND WOMEN S HOSPITAL   (United States)

more..

Author keywords

Diamond Blackfan anemia; erythropoiesis; GATA1; genetics; hematopoiesis; lineage commitment; ribosome; translation

Indexed keywords

RIBOSOME PROTEIN; TRANSCRIPTION FACTOR GATA 1; APOPTOSIS REGULATORY PROTEIN; GATA1 PROTEIN, HUMAN; RIBOSOMAL PROTEIN L5, HUMAN; RIBOSOMAL PROTEIN S19; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TSR2 PROTEIN, HUMAN;

5' UNTRANSLATED REGION; ARTICLE; BLACKFAN DIAMOND ANEMIA; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROID LINEAGE; GENE; GENE MUTATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; RIBOSOME; TRANSLATION REGULATION; TSR2 GENE; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CELL CULTURE; CYTOLOGY; FEMALE; GENETICS; MALE; METABOLISM; MISSENSE MUTATION; PATHOLOGY; RNA INTERFERENCE;

5' UNTRANSLATED REGIONS; ANEMIA, DIAMOND-BLACKFAN; APOPTOSIS REGULATORY PROTEINS; BONE MARROW CELLS; CELLS, CULTURED; FEMALE; GATA1 TRANSCRIPTION FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MUTATION, MISSENSE; RIBOSOMAL PROTEINS; RIBOSOMES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 85044153468     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.02.036     Document Type: Article

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