Oligodendrocyte Progenitor Cells and Macrophages/Microglia Produce Glioma Stem Cell Niches at the Tumor Border

EBioMedicine

Volumn 30, Issue , 2018, Pages 94-104

  Hide, Takuichiro ^a   Komohara, Yoshihiro ^a   Miyasato, Yuko ^a   Nakamura, Hideo ^a   Makino, Keishi ^a   Takeya, Motohiro ^a   Kuratsu, Jun ichi ^a   Mukasa, Akitake ^a   Yano, Shigetoshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Border niche; Chemoradioresistance; Glioblastoma; Glioma stem cells niche; Macrophage; Microglia; microRNA; Oligodendrocyte progenitor cell; Recurrence; Stemness

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; COMPLEMENT COMPONENT C5A; EGF CONTAINING FIBURIN LIKE EXTRACELLULAR MATRIX PROTEIN 1; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MICRORNA; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; ONCOSTATIN M; OSTEOPONTIN; PEPTIDES AND PROTEINS; PLACENTAL GROWTH FACTOR 1; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; STAT3 PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; CEREBROSPINAL FLUID; COLONY FORMATION; CONTROLLED STUDY; EXPERIMENTAL NEOPLASM; FEMALE; GENE EXPRESSION; GLIOMA STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGE; MAJOR CLINICAL STUDY; METASTASIS; MICROARRAY ANALYSIS; MICROGLIA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLIGODENDROCYTE PRECURSOR CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; WESTERN BLOTTING; WHITE MATTER; BRAIN TUMOR; CANCER STEM CELL; CELL COMMUNICATION; CELL LINEAGE; CELL SURVIVAL; CONDITIONED MEDIUM; DRUG EFFECT; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; PHARMACOLOGY; STEM CELL NICHE; TUMOR CELL LINE; TUMOR RECURRENCE;

BRAIN NEOPLASMS; CELL COMMUNICATION; CELL LINE, TUMOR; CELL LINEAGE; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MACROPHAGES; MICROGLIA; MICRORNAS; NEOPLASM RECURRENCE, LOCAL; NEOPLASTIC STEM CELLS; OLIGODENDROCYTE PRECURSOR CELLS; SPHEROIDS, CELLULAR; STEM CELL NICHE; WHITE MATTER;

EID: 85043980147     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2018.02.024     Document Type: Article

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