-
1
-
-
77749338221
-
Recent advances in therapy for glioblastoma
-
Clarke J., Butowski N., Chang S. Recent advances in therapy for glioblastoma. Arch. Neurol. 2010, 67:279-283.
-
(2010)
Arch. Neurol.
, vol.67
, pp. 279-283
-
-
Clarke, J.1
Butowski, N.2
Chang, S.3
-
2
-
-
59149086517
-
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma
-
Prados M.D., Chang S.M., Butowski N., DeBoer R., Parvataneni R., Carliner H., Kabuubi P., Ayers-Ringler J., Rabbitt J., Page M., Fedoroff A., Sneed P.K., Berger M.S., McDermott M.W., Parsa A.T., Vandenberg S., James C.D., Lamborn K.R., Stokoe D., Haas-Kogan D.A. Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. J. Clin. Oncol. 2009, 27:579-584.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 579-584
-
-
Prados, M.D.1
Chang, S.M.2
Butowski, N.3
DeBoer, R.4
Parvataneni, R.5
Carliner, H.6
Kabuubi, P.7
Ayers-Ringler, J.8
Rabbitt, J.9
Page, M.10
Fedoroff, A.11
Sneed, P.K.12
Berger, M.S.13
McDermott, M.W.14
Parsa, A.T.15
Vandenberg, S.16
James, C.D.17
Lamborn, K.R.18
Stokoe, D.19
Haas-Kogan, D.A.20
more..
-
3
-
-
34249332411
-
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
Beier D., Hau P., Proescholdt M., Lohmeier A., Wischhusen J., Oefner P.J., Aigner L., Brawanski A., Bogdahn U., Beier C.P. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res. 2007, 67:4010-4015.
-
(2007)
Cancer Res.
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
Lohmeier, A.4
Wischhusen, J.5
Oefner, P.J.6
Aigner, L.7
Brawanski, A.8
Bogdahn, U.9
Beier, C.P.10
-
4
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R., Binda E., Orfanelli U., Cipelletti B., Gritti A., De Vitis S., Fiocco R., Foroni C., Dimeco F., Vescovi A. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 2004, 64:7011-7021.
-
(2004)
Cancer Res.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
5
-
-
34648821254
-
Making a tumour's bed: glioblastoma stem cells and the vascular niche
-
Gilbertson R.J., Rich J.N. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat. Rev. Cancer 2007, 7:733-736.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
6
-
-
84876487189
-
Targeting cancer stem cells for treatment of glioblastoma multiforme
-
Cho D.Y., Lin S.Z., Yang W.K., Lee H.C., Hsu D.M., Lin H.L., Chen C.C., Liu C.L., Lee W.Y., Ho L.H. Targeting cancer stem cells for treatment of glioblastoma multiforme. Cell Transplant. 2013, 22:731-739.
-
(2013)
Cell Transplant.
, vol.22
, pp. 731-739
-
-
Cho, D.Y.1
Lin, S.Z.2
Yang, W.K.3
Lee, H.C.4
Hsu, D.M.5
Lin, H.L.6
Chen, C.C.7
Liu, C.L.8
Lee, W.Y.9
Ho, L.H.10
-
7
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
8
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu G., Yuan X., Zeng Z., Tunici P., Ng H., Abdulkadir I.R., Lu L., Irvin D., Black K.L., Yu J.S. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol. Cancer 2006, 5:67.
-
(2006)
Mol. Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
Lu, L.7
Irvin, D.8
Black, K.L.9
Yu, J.S.10
-
9
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
Tsai M.Y., Wiese C., Cao K., Martin O., Donovan P., Ruderman J., Prigent C., Zheng Y. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat. Cell Biol. 2003, 5:242-248.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 242-248
-
-
Tsai, M.Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
11
-
-
2342639645
-
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
-
Harrington E.A., Bebbington D., Moore J., Rasmussen R.K., Ajose-Adeogun A.O., Nakayama T., Graham J.A., Demur C., Hercend T., Diu-Hercend A., Su M., Golec J.M., Miller K.M. VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat. Med. 2004, 10:262-267.
-
(2004)
Nat. Med.
, vol.10
, pp. 262-267
-
-
Harrington, E.A.1
Bebbington, D.2
Moore, J.3
Rasmussen, R.K.4
Ajose-Adeogun, A.O.5
Nakayama, T.6
Graham, J.A.7
Demur, C.8
Hercend, T.9
Diu-Hercend, A.10
Su, M.11
Golec, J.M.12
Miller, K.M.13
-
12
-
-
0037386929
-
Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer
-
Gritsko T.M., Coppola D., Paciga J.E., Yang L., Sun M., Shelley S.A., Fiorica J.V., Nicosia S.V., Cheng J.Q. Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer. Clin. Cancer Res. 2003, 9:1420-1426.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1420-1426
-
-
Gritsko, T.M.1
Coppola, D.2
Paciga, J.E.3
Yang, L.4
Sun, M.5
Shelley, S.A.6
Fiorica, J.V.7
Nicosia, S.V.8
Cheng, J.Q.9
-
13
-
-
77954370343
-
Aurora kinase A as a rational target for therapy in glioblastoma
-
Barton V.N., Foreman N.K., Donson A.M., Birks D.K., Handler M.H., Vibhakar R. Aurora kinase A as a rational target for therapy in glioblastoma. J. Neurosurg. Pediatr. 2010, 6:98-105.
-
(2010)
J. Neurosurg. Pediatr.
, vol.6
, pp. 98-105
-
-
Barton, V.N.1
Foreman, N.K.2
Donson, A.M.3
Birks, D.K.4
Handler, M.H.5
Vibhakar, R.6
-
14
-
-
71749103630
-
Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features
-
Samaras V., Stamatelli A., Samaras E., Arnaoutoglou C., Arnaoutoglou M., Stergiou I., Konstantopoulou P., Varsos V., Karameris A., Barbatis C. Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features. Pathol. Res. Pract. 2009, 205:765-773.
-
(2009)
Pathol. Res. Pract.
, vol.205
, pp. 765-773
-
-
Samaras, V.1
Stamatelli, A.2
Samaras, E.3
Arnaoutoglou, C.4
Arnaoutoglou, M.5
Stergiou, I.6
Konstantopoulou, P.7
Varsos, V.8
Karameris, A.9
Barbatis, C.10
-
15
-
-
77955167447
-
Translational up-regulation of Aurora-A in EGFR-overexpressed cancer
-
Lai C.H., Tseng J.T., Lee Y.C., Chen Y.J., Lee J.C., Lin B.W., Huang T.C., Liu Y.W., Leu T.H., Liu Y.W., Chen Y.P., Chang W.C., Hung L.Y. Translational up-regulation of Aurora-A in EGFR-overexpressed cancer. J. Cell Mol. Med. 2010, 14:1520-1531.
-
(2010)
J. Cell Mol. Med.
, vol.14
, pp. 1520-1531
-
-
Lai, C.H.1
Tseng, J.T.2
Lee, Y.C.3
Chen, Y.J.4
Lee, J.C.5
Lin, B.W.6
Huang, T.C.7
Liu, Y.W.8
Leu, T.H.9
Liu, Y.W.10
Chen, Y.P.11
Chang, W.C.12
Hung, L.Y.13
-
16
-
-
84864631288
-
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling
-
Lee D.F., Su J., Ang Y.S., Carvajal-Vergara X., Mulero-Navarro S., Pereira C.F., Gingold J., Wang H.L., Zhao R., Sevilla A., Darr H., Williamson A.J., Chang B., Niu X., Aguilo F., Flores E.R., Sher Y.P., Hung M.C., Whetton A.D., Gelb B.D., Moore K.A., Snoeck H.W., Ma'ayan A., Schaniel C., Lemischka I.R. Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell 2012, 11:179-194.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 179-194
-
-
Lee, D.F.1
Su, J.2
Ang, Y.S.3
Carvajal-Vergara, X.4
Mulero-Navarro, S.5
Pereira, C.F.6
Gingold, J.7
Wang, H.L.8
Zhao, R.9
Sevilla, A.10
Darr, H.11
Williamson, A.J.12
Chang, B.13
Niu, X.14
Aguilo, F.15
Flores, E.R.16
Sher, Y.P.17
Hung, M.C.18
Whetton, A.D.19
Gelb, B.D.20
Moore, K.A.21
Snoeck, H.W.22
Ma'ayan, A.23
Schaniel, C.24
Lemischka, I.R.25
more..
-
17
-
-
52949115363
-
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization
-
Wirtz-Peitz F., Nishimura T., Knoblich J.A. Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 2008, 135:161-173.
-
(2008)
Cell
, vol.135
, pp. 161-173
-
-
Wirtz-Peitz, F.1
Nishimura, T.2
Knoblich, J.A.3
-
18
-
-
61649100307
-
The FGF family: biology, pathophysiology and therapy
-
Beenken A., Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat. Rev. Drug Discov. 2009, 8:235-253.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 235-253
-
-
Beenken, A.1
Mohammadi, M.2
-
19
-
-
26244457001
-
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
-
Haugsten E.M., Sorensen V., Brech A., Olsnes S., Wesche J. Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors. J. Cell Sci. 2005, 118:3869-3881.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3869-3881
-
-
Haugsten, E.M.1
Sorensen, V.2
Brech, A.3
Olsnes, S.4
Wesche, J.5
-
20
-
-
84876138469
-
Leukemia inhibitory factor-induced Stat3 signaling suppresses fibroblast growth factor 1-induced Erk1/2 activation to inhibit the downstream differentiation in mouse embryonic stem cells
-
Liu J.W., Hsu Y.C., Kao C.Y., Su H.L., Chiu I.M. Leukemia inhibitory factor-induced Stat3 signaling suppresses fibroblast growth factor 1-induced Erk1/2 activation to inhibit the downstream differentiation in mouse embryonic stem cells. Stem Cells Dev. 2013, 22:1190-1197.
-
(2013)
Stem Cells Dev.
, vol.22
, pp. 1190-1197
-
-
Liu, J.W.1
Hsu, Y.C.2
Kao, C.Y.3
Su, H.L.4
Chiu, I.M.5
-
21
-
-
0027509359
-
Gene structure and differential expression of acidic fibroblast growth factor mRNA: identification and distribution of four different transcripts
-
Myers R.L., Payson R.A., Chotani M.A., Deaven L.L., Chiu I.M. Gene structure and differential expression of acidic fibroblast growth factor mRNA: identification and distribution of four different transcripts. Oncogene 1993, 8:341-349.
-
(1993)
Oncogene
, vol.8
, pp. 341-349
-
-
Myers, R.L.1
Payson, R.A.2
Chotani, M.A.3
Deaven, L.L.4
Chiu, I.M.5
-
22
-
-
0029089855
-
Different fibroblast growth factor 1 (FGF-1) transcripts in neural tissues, glioblastomas and kidney carcinoma cell lines
-
Myers R.L., Chedid M., Tronick S.R., Chiu I.M. Different fibroblast growth factor 1 (FGF-1) transcripts in neural tissues, glioblastomas and kidney carcinoma cell lines. Oncogene 1995, 11:785-789.
-
(1995)
Oncogene
, vol.11
, pp. 785-789
-
-
Myers, R.L.1
Chedid, M.2
Tronick, S.R.3
Chiu, I.M.4
-
23
-
-
0028940090
-
Functional characterization of the brain-specific FGF-1 promoter, FGF-1.B
-
Myers R.L., Ray S.K., Eldridge R., Chotani M.A., Chiu I.M. Functional characterization of the brain-specific FGF-1 promoter, FGF-1.B. J. Biol. Chem. 1995, 270:8257-8266.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8257-8266
-
-
Myers, R.L.1
Ray, S.K.2
Eldridge, R.3
Chotani, M.A.4
Chiu, I.M.5
-
24
-
-
84861047531
-
A PPARgamma-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
-
Jonker J.W., Suh J.M., Atkins A.R., Ahmadian M., Li P., Whyte J., He M., Juguilon H., Yin Y.Q., Phillips C.T., Yu R.T., Olefsky J.M., Henry R.R., Downes M., Evans R.M. A PPARgamma-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature 2012, 485:391-394.
-
(2012)
Nature
, vol.485
, pp. 391-394
-
-
Jonker, J.W.1
Suh, J.M.2
Atkins, A.R.3
Ahmadian, M.4
Li, P.5
Whyte, J.6
He, M.7
Juguilon, H.8
Yin, Y.Q.9
Phillips, C.T.10
Yu, R.T.11
Olefsky, J.M.12
Henry, R.R.13
Downes, M.14
Evans, R.M.15
-
25
-
-
0034649501
-
Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter
-
Chiu I.M., Touhalisky K., Liu Y., Yates A., Frostholm A. Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter. Oncogene 2000, 19:6229-6239.
-
(2000)
Oncogene
, vol.19
, pp. 6229-6239
-
-
Chiu, I.M.1
Touhalisky, K.2
Liu, Y.3
Yates, A.4
Frostholm, A.5
-
26
-
-
84922763762
-
Human FGF1 promoter is active in ependymal cells and dopaminergic neurons in the brains of F1B-GFP transgenic mice
-
Chen M.S., Lin H.K., Chiu H., Lee D.C., Chung Y.F., Chiu I.M. Human FGF1 promoter is active in ependymal cells and dopaminergic neurons in the brains of F1B-GFP transgenic mice. Dev. Neurobiol. 2015, 75:232-248.
-
(2015)
Dev. Neurobiol.
, vol.75
, pp. 232-248
-
-
Chen, M.S.1
Lin, H.K.2
Chiu, H.3
Lee, D.C.4
Chung, Y.F.5
Chiu, I.M.6
-
27
-
-
59649084032
-
Brain-specific 1B promoter of FGF1 gene facilitates the isolation of neural stem/progenitor cells with self-renewal and multipotent capacities
-
Hsu Y.C., Lee D.C., Chen S.L., Liao W.C., Lin J.W., Chiu W.T., Chiu I.M. Brain-specific 1B promoter of FGF1 gene facilitates the isolation of neural stem/progenitor cells with self-renewal and multipotent capacities. Dev. Dyn. 2009, 238:302-314.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 302-314
-
-
Hsu, Y.C.1
Lee, D.C.2
Chen, S.L.3
Liao, W.C.4
Lin, J.W.5
Chiu, W.T.6
Chiu, I.M.7
-
28
-
-
67349258579
-
Isolation of neural stem/progenitor cells by using EGF/FGF1 and FGF1B promoter-driven green fluorescence from embryonic and adult mouse brains
-
Lee D.C., Hsu Y.C., Chung Y.F., Hsiao C.Y., Chen S.L., Chen M.S., Lin H.K., Chiu I.M. Isolation of neural stem/progenitor cells by using EGF/FGF1 and FGF1B promoter-driven green fluorescence from embryonic and adult mouse brains. Mol. Cell. Neurosci. 2009, 41:348-363.
-
(2009)
Mol. Cell. Neurosci.
, vol.41
, pp. 348-363
-
-
Lee, D.C.1
Hsu, Y.C.2
Chung, Y.F.3
Hsiao, C.Y.4
Chen, S.L.5
Chen, M.S.6
Lin, H.K.7
Chiu, I.M.8
-
29
-
-
77951535377
-
Regulation of FGF1 gene promoter through transcription factor RFX1
-
Hsu Y.C., Liao W.C., Kao C.Y., Chiu I.M. Regulation of FGF1 gene promoter through transcription factor RFX1. J. Biol. Chem. 2010, 285:13885-13895.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13885-13895
-
-
Hsu, Y.C.1
Liao, W.C.2
Kao, C.Y.3
Chiu, I.M.4
-
30
-
-
84861033031
-
Ciliogenic RFX transcription factors regulate FGF1 gene promoter
-
Hsu Y.C., Kao C.Y., Chung Y.F., Chen M.S., Chiu I.M. Ciliogenic RFX transcription factors regulate FGF1 gene promoter. J. Cell. Biochem. 2012, 113:2511-2522.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 2511-2522
-
-
Hsu, Y.C.1
Kao, C.Y.2
Chung, Y.F.3
Chen, M.S.4
Chiu, I.M.5
-
31
-
-
84906826372
-
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer
-
Suh J.M., Jonker J.W., Ahmadian M., Goetz R., Lackey D., Osborn O., Huang Z., Liu W., Yoshihara E., van Dijk T.H., Havinga R., Fan W., Yin Y.Q., Yu R.T., Liddle C., Atkins A.R., Olefsky J.M., Mohammadi M., Downes M., Evans R.M. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature 2014, 513:436-439.
-
(2014)
Nature
, vol.513
, pp. 436-439
-
-
Suh, J.M.1
Jonker, J.W.2
Ahmadian, M.3
Goetz, R.4
Lackey, D.5
Osborn, O.6
Huang, Z.7
Liu, W.8
Yoshihara, E.9
van Dijk, T.H.10
Havinga, R.11
Fan, W.12
Yin, Y.Q.13
Yu, R.T.14
Liddle, C.15
Atkins, A.R.16
Olefsky, J.M.17
Mohammadi, M.18
Downes, M.19
Evans, R.M.20
more..
-
32
-
-
84866749750
-
P53 negatively regulates Aurora A via both transcriptional and posttranslational regulation
-
Wu C.C., Yang T.Y., Yu C.T., Phan L., Ivan C., Sood A.K., Hsu S.L., Lee M.H. p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle 2012, 11:3433-3442.
-
(2012)
Cell Cycle
, vol.11
, pp. 3433-3442
-
-
Wu, C.C.1
Yang, T.Y.2
Yu, C.T.3
Phan, L.4
Ivan, C.5
Sood, A.K.6
Hsu, S.L.7
Lee, M.H.8
-
33
-
-
9444287030
-
Common and distinct elements in cellular signaling via EGF and FGF receptors
-
Schlessinger J. Common and distinct elements in cellular signaling via EGF and FGF receptors. Science 2004, 306:1506-1507.
-
(2004)
Science
, vol.306
, pp. 1506-1507
-
-
Schlessinger, J.1
-
34
-
-
20344387214
-
Conditional transgenic system for mouse Aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein
-
Fukuda T., Mishina Y., Walker M.P., DiAugustine R.P. Conditional transgenic system for mouse Aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Mol. Cell. Biol. 2005, 25:5270-5281.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5270-5281
-
-
Fukuda, T.1
Mishina, Y.2
Walker, M.P.3
DiAugustine, R.P.4
-
35
-
-
0034730750
-
The small GTPases Ras, Rac, and Cdc42 transcriptionally regulate expression of human fibroblast growth factor 1
-
Chotani M.A., Touhalisky K., Chiu M. The small GTPases Ras, Rac, and Cdc42 transcriptionally regulate expression of human fibroblast growth factor 1. J. Biol. Chem. 2000, 275:30432-30438.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30432-30438
-
-
Chotani, M.A.1
Touhalisky, K.2
Chiu, M.3
-
36
-
-
84857230742
-
Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas
-
Lehman N.L., O'Donnell J.P., Whiteley L.J., Stapp R.T., Lehman T.D., Roszka K.M., Schultz L.R., Williams C.J., Mikkelsen T., Brown S.L., Ecsedy J.A., Poisson L.M. Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas. Cell Cycle 2012, 11:489-502.
-
(2012)
Cell Cycle
, vol.11
, pp. 489-502
-
-
Lehman, N.L.1
O'Donnell, J.P.2
Whiteley, L.J.3
Stapp, R.T.4
Lehman, T.D.5
Roszka, K.M.6
Schultz, L.R.7
Williams, C.J.8
Mikkelsen, T.9
Brown, S.L.10
Ecsedy, J.A.11
Poisson, L.M.12
-
37
-
-
84896702422
-
The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture
-
Haley E.M., Kim Y. The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture. Cancer Lett. 2014, 346:1-5.
-
(2014)
Cancer Lett.
, vol.346
, pp. 1-5
-
-
Haley, E.M.1
Kim, Y.2
-
38
-
-
34247259822
-
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
-
Manfredi M.G., Ecsedy J.A., Meetze K.A., Balani S.K., Burenkova O., Chen W., Galvin K.M., Hoar K.M., Huck J.J., LeRoy P.J., Ray E.T., Sells T.B., Stringer B., Stroud S.G., Vos T.J., Weatherhead G.S., Wysong D.R., Zhang M., Bolen J.B., Claiborne C.F. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc. Natl. Acad. Sci. USA 2007, 104:4106-4111.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4106-4111
-
-
Manfredi, M.G.1
Ecsedy, J.A.2
Meetze, K.A.3
Balani, S.K.4
Burenkova, O.5
Chen, W.6
Galvin, K.M.7
Hoar, K.M.8
Huck, J.J.9
LeRoy, P.J.10
Ray, E.T.11
Sells, T.B.12
Stringer, B.13
Stroud, S.G.14
Vos, T.J.15
Weatherhead, G.S.16
Wysong, D.R.17
Zhang, M.18
Bolen, J.B.19
Claiborne, C.F.20
more..
-
39
-
-
79955913373
-
A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-A
-
Huang Y.-H., Wu C.-C., Chou C.-K., Huang C.-Y.F. A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-A. PLoS One 2011, 6:e19718.
-
(2011)
PLoS One
, vol.6
-
-
Huang, Y.-H.1
Wu, C.-C.2
Chou, C.-K.3
Huang, C.-Y.F.4
-
40
-
-
36749004944
-
Mechanisms controlling cell cycle exit upon terminal differentiation
-
Buttitta L.A., Edgar B.A. Mechanisms controlling cell cycle exit upon terminal differentiation. Curr. Opin. Cell Biol. 2007, 19:697-704.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 697-704
-
-
Buttitta, L.A.1
Edgar, B.A.2
-
41
-
-
84865322562
-
Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results
-
Berendsen S., Broekman M., Seute T., Snijders T., van Es C., de Vos F., Regli L., Robe P. Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results. Expert Opin. Investig. Drugs 2012, 21:1391-1415.
-
(2012)
Expert Opin. Investig. Drugs
, vol.21
, pp. 1391-1415
-
-
Berendsen, S.1
Broekman, M.2
Seute, T.3
Snijders, T.4
van Es, C.5
de Vos, F.6
Regli, L.7
Robe, P.8
-
42
-
-
84879410872
-
The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities
-
Kao C.Y., Hsu Y.C., Liu J.W., Lee D.C., Chung Y.F., Chiu I.M. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J. Neurochem. 2013, 126:4-18.
-
(2013)
J. Neurochem.
, vol.126
, pp. 4-18
-
-
Kao, C.Y.1
Hsu, Y.C.2
Liu, J.W.3
Lee, D.C.4
Chung, Y.F.5
Chiu, I.M.6
-
43
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255:1707-1710.
-
(1992)
Science
, vol.255
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
44
-
-
0027491410
-
BFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
-
Vescovi A.L., Reynolds B.A., Fraser D.D., Weiss S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 1993, 11:951-966.
-
(1993)
Neuron
, vol.11
, pp. 951-966
-
-
Vescovi, A.L.1
Reynolds, B.A.2
Fraser, D.D.3
Weiss, S.4
-
45
-
-
69249234742
-
Glioblastoma cell growth is suppressed by disruption of fibroblast growth factor pathway signaling
-
Loilome W., Joshi A.D., ap Rhys C.M., Piccirillo S., Vescovi A.L., Gallia G.L., Riggins G.J. Glioblastoma cell growth is suppressed by disruption of fibroblast growth factor pathway signaling. J. Neurooncol. 2009, 94:359-366.
-
(2009)
J. Neurooncol.
, vol.94
, pp. 359-366
-
-
Loilome, W.1
Joshi, A.D.2
ap Rhys, C.M.3
Piccirillo, S.4
Vescovi, A.L.5
Gallia, G.L.6
Riggins, G.J.7
-
46
-
-
0032578009
-
Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration
-
LaVallee T.M., Prudovsky I.A., McMahon G.A., Hu X., Maciag T. Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J. Cell Biol. 1998, 141:1647-1658.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1647-1658
-
-
LaVallee, T.M.1
Prudovsky, I.A.2
McMahon, G.A.3
Hu, X.4
Maciag, T.5
-
47
-
-
26244459598
-
FGF-1 and S100A13 possibly contribute to angiogenesis in endometriosis
-
Hayrabedyan S., Kyurkchiev S., Kehayov I. FGF-1 and S100A13 possibly contribute to angiogenesis in endometriosis. J. Reprod. Immunol. 2005, 67:87-101.
-
(2005)
J. Reprod. Immunol.
, vol.67
, pp. 87-101
-
-
Hayrabedyan, S.1
Kyurkchiev, S.2
Kehayov, I.3
-
48
-
-
84874555267
-
A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis
-
Mori S., Tran V., Nishikawa K., Kaneda T., Hamada Y., Kawaguchi N., Fujita M., Saegusa J., Takada Y.K., Matsuura N., Zhao M., Takada Y. A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis. PLoS One 2013, 8:e57927.
-
(2013)
PLoS One
, vol.8
-
-
Mori, S.1
Tran, V.2
Nishikawa, K.3
Kaneda, T.4
Hamada, Y.5
Kawaguchi, N.6
Fujita, M.7
Saegusa, J.8
Takada, Y.K.9
Matsuura, N.10
Zhao, M.11
Takada, Y.12
-
51
-
-
33745198882
-
Chemotherapy resistance of glioblastoma stem cells
-
Eramo A., Ricci-Vitiani L., Zeuner A., Pallini R., Lotti F., Sette G., Pilozzi E., Larocca L.M., Peschle C., De Maria R. Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ. 2006, 13:1238-1241.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1238-1241
-
-
Eramo, A.1
Ricci-Vitiani, L.2
Zeuner, A.3
Pallini, R.4
Lotti, F.5
Sette, G.6
Pilozzi, E.7
Larocca, L.M.8
Peschle, C.9
De Maria, R.10
-
52
-
-
47549118837
-
Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice
-
Zhang D., Shimizu T., Araki N., Hirota T., Yoshie M., Ogawa K., Nakagata N., Takeya M., Saya H. Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice. Oncogene 2008, 27:4305-4314.
-
(2008)
Oncogene
, vol.27
, pp. 4305-4314
-
-
Zhang, D.1
Shimizu, T.2
Araki, N.3
Hirota, T.4
Yoshie, M.5
Ogawa, K.6
Nakagata, N.7
Takeya, M.8
Saya, H.9
-
53
-
-
79952585985
-
Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities
-
Jantscher F., Pirker C., Mayer C.E., Berger W., Sutterluety H. Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities. Mol. Cancer 2011, 10:28.
-
(2011)
Mol. Cancer
, vol.10
, pp. 28
-
-
Jantscher, F.1
Pirker, C.2
Mayer, C.E.3
Berger, W.4
Sutterluety, H.5
-
54
-
-
84859725892
-
Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells
-
Borges K.S., Castro-Gamero A.M., Moreno D.A., da Silva Silveira V., Brassesco M.S., de Paula Queiroz R.G., de Oliveira H.F., Carlotti C.G., Scrideli C.A., Tone L.G. Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells. J. Cancer Res. Clin. Oncol. 2012, 138:405-414.
-
(2012)
J. Cancer Res. Clin. Oncol.
, vol.138
, pp. 405-414
-
-
Borges, K.S.1
Castro-Gamero, A.M.2
Moreno, D.A.3
da Silva Silveira, V.4
Brassesco, M.S.5
de Paula Queiroz, R.G.6
de Oliveira, H.F.7
Carlotti, C.G.8
Scrideli, C.A.9
Tone, L.G.10
-
55
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
-
Pugacheva E.N., Golemis E.A. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat. Cell Biol. 2005, 7:937-946.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
56
-
-
0242330123
-
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
-
Bayliss R., Sardon T., Vernos I., Conti E. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol. Cell 2003, 12:851-862.
-
(2003)
Mol. Cell
, vol.12
, pp. 851-862
-
-
Bayliss, R.1
Sardon, T.2
Vernos, I.3
Conti, E.4
-
57
-
-
33751200630
-
IKKalpha regulates the mitotic phase of the cell cycle by modulating Aurora A phosphorylation
-
Prajapati S., Tu Z., Yamamoto Y., Gaynor R.B. IKKalpha regulates the mitotic phase of the cell cycle by modulating Aurora A phosphorylation. Cell Cycle 2006, 5:2371-2380.
-
(2006)
Cell Cycle
, vol.5
, pp. 2371-2380
-
-
Prajapati, S.1
Tu, Z.2
Yamamoto, Y.3
Gaynor, R.B.4
-
58
-
-
69949135718
-
Aurora A moonlights in neurite extension
-
Lefkowitz G.K., Gleeson J.G. Aurora A moonlights in neurite extension. Nat. Cell Biol. 2009, 11:1053-1054.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1053-1054
-
-
Lefkowitz, G.K.1
Gleeson, J.G.2
-
59
-
-
79955395626
-
VX680 binding in Aurora A: pi-pi interactions involving the conserved aromatic amino acid of the flexible glycine-rich loop
-
Oliveira T.M., Ahmad R., Engh R.A. VX680 binding in Aurora A: pi-pi interactions involving the conserved aromatic amino acid of the flexible glycine-rich loop. J. Phys. Chem. A 2011, 115:3895-3904.
-
(2011)
J. Phys. Chem. A
, vol.115
, pp. 3895-3904
-
-
Oliveira, T.M.1
Ahmad, R.2
Engh, R.A.3
-
60
-
-
28344434370
-
FGF1 inhibits p53-dependent apoptosis and cell cycle arrest via an intracrine pathway
-
Bouleau S., Grimal H., Rincheval V., Godefroy N., Mignotte B., Vayssiere J.L., Renaud F. FGF1 inhibits p53-dependent apoptosis and cell cycle arrest via an intracrine pathway. Oncogene 2005, 24:7839-7849.
-
(2005)
Oncogene
, vol.24
, pp. 7839-7849
-
-
Bouleau, S.1
Grimal, H.2
Rincheval, V.3
Godefroy, N.4
Mignotte, B.5
Vayssiere, J.L.6
Renaud, F.7
-
61
-
-
0026526516
-
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
-
Reynolds B.A., Tetzlaff W., Weiss S. A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J. Neurosci. 1992, 12:4565-4574.
-
(1992)
J. Neurosci.
, vol.12
, pp. 4565-4574
-
-
Reynolds, B.A.1
Tetzlaff, W.2
Weiss, S.3
-
62
-
-
78650968492
-
Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner
-
Le Belle J.E., Orozco N.M., Paucar A.A., Saxe J.P., Mottahedeh J., Pyle A.D., Wu H., Kornblum H.I. Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell 2011, 8:59-71.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 59-71
-
-
Le Belle, J.E.1
Orozco, N.M.2
Paucar, A.A.3
Saxe, J.P.4
Mottahedeh, J.5
Pyle, A.D.6
Wu, H.7
Kornblum, H.I.8
-
63
-
-
66049085403
-
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
-
Pollard S.M., Yoshikawa K., Clarke I.D., Danovi D., Stricker S., Russell R., Bayani J., Head R., Lee M., Bernstein M., Squire J.A., Smith A., Dirks P. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 2009, 4:568-580.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 568-580
-
-
Pollard, S.M.1
Yoshikawa, K.2
Clarke, I.D.3
Danovi, D.4
Stricker, S.5
Russell, R.6
Bayani, J.7
Head, R.8
Lee, M.9
Bernstein, M.10
Squire, J.A.11
Smith, A.12
Dirks, P.13
-
64
-
-
0037390975
-
Expression of tubulin beta II in neural stem/progenitor cells and radial fibers during human fetal brain development
-
Nakamura Y., Yamamoto M., Oda E., Yamamoto A., Kanemura Y., Hara M., Suzuki A., Yamasaki M., Okano H. Expression of tubulin beta II in neural stem/progenitor cells and radial fibers during human fetal brain development. Lab. Investig. 2003, 83:479-489.
-
(2003)
Lab. Investig.
, vol.83
, pp. 479-489
-
-
Nakamura, Y.1
Yamamoto, M.2
Oda, E.3
Yamamoto, A.4
Kanemura, Y.5
Hara, M.6
Suzuki, A.7
Yamasaki, M.8
Okano, H.9
-
65
-
-
0141483083
-
Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-GFP knock-in mice
-
Aubert J., Stavridis M.P., Tweedie S., O'Reilly M., Vierlinger K., Li M., Ghazal P., Pratt T., Mason J.O., Roy D., Smith A. Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-GFP knock-in mice. Proc. Natl. Acad. Sci. USA 2003, 100(Suppl. 1):11836-11841.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11836-11841
-
-
Aubert, J.1
Stavridis, M.P.2
Tweedie, S.3
O'Reilly, M.4
Vierlinger, K.5
Li, M.6
Ghazal, P.7
Pratt, T.8
Mason, J.O.9
Roy, D.10
Smith, A.11
-
66
-
-
84858249479
-
Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells
-
Sheikh B.N., Dixon M.P., Thomas T., Voss A.K. Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells. J. Cell Sci. 2012, 125:295-309.
-
(2012)
J. Cell Sci.
, vol.125
, pp. 295-309
-
-
Sheikh, B.N.1
Dixon, M.P.2
Thomas, T.3
Voss, A.K.4
-
67
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh S.K., Clarke I.D., Terasaki M., Bonn V.E., Hawkins C., Squire J., Dirks P.B. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003, 63:5821-5828.
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
68
-
-
66149152637
-
Limits of CD133 as a marker of glioma self-renewing cells
-
Clement V., Dutoit V., Marino D., Dietrich P.Y., Radovanovic I. Limits of CD133 as a marker of glioma self-renewing cells. Int. J. Cancer 2009, 125:244-248.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 244-248
-
-
Clement, V.1
Dutoit, V.2
Marino, D.3
Dietrich, P.Y.4
Radovanovic, I.5
|