Histological Characterization of the tumorigenic "peri-necrotic niche" harboring quiescent stem-like tumor cells in glioblastoma

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Ishii, Aya ^a   Kimura, Tokuhiro ^a   Sadahiro, Hirokazu ^a   Kawano, Hiroo ^a   Takubo, Keiyo ^b   Suzuki, Michiyasu ^a   Ikeda, Eiji ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHOSERINE; RNA POLYMERASE II; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; HIF1A PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; NANOG PROTEIN, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX; TUMOR MARKER;

ARTICLE; ASTROCYTOMA; BRAIN BLOOD VESSEL; CANCER GRADING; CARCINOGENICITY; CELL POPULATION; CONTROLLED STUDY; GANGRENE; GLIOBLASTOMA; GLIOMA STEM CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PERI-NECROTIC NICHE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUIESCENT STEM LIKE TUMOR CELL; SPHEROID CELL; STEM CELL NICHE; TUMOR MICROENVIRONMENT; ADULT; AGED; CANCER STEM CELL; CYTOLOGY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; TUMOR CELL CULTURE; YOUNG ADULT;

ADULT; AGED; ASTROCYTOMA; BIOMARKERS, TUMOR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLIOBLASTOMA; HOMEODOMAIN PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MIDDLE AGED; NANOG HOMEOBOX PROTEIN; NEOPLASTIC STEM CELLS; SOXB1 TRANSCRIPTION FACTORS; STEM CELL NICHE; TUMOR CELLS, CULTURED; YOUNG ADULT;

EID: 84958230967     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147366     Document Type: Article

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