Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype

Nature Immunology

Volumn 17, Issue 11, 2016, Pages 1282-1290

  Shen, Xianli ^a   Burguillos, Miguel A ^a,g   Osman, Ahmed M ^b   Frijhoff, Jeroen ^a,h   Carrillo Jiménez, Alejandro ^c,d   Kanatani, Sachie ^a,e   Augsten, Martin ^a,i   Saidi, Dalel ^a   Rodhe, Johanna ^a   Kavanagh, Edel ^a   Rongvaux, Anthony ^f,j   Rraklli, Vilma ^a   Nyman, Ulrika ^a   Holmberg, Johan ^a   Östman, Arne ^a   Flavell, Richard A ^f   Barragan, Antonio ^a,e   Venero, Jose Luis ^c,d   Blomgren, Klas ^b   Joseph, Bertrand ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF SEVILLE   (Spain)

^d HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^e STOCKHOLM UNIVERSITY   (Sweden)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^h MAASTRICHT UNIVERSITY   (Netherlands)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^j Fred Hutchinson Cancer Research Center   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CHEMOKINE RECEPTOR CX3CR1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; MATRIX METALLOPROTEINASE 14; PROCASPASE 3; SMALL INTERFERING RNA; THIOREDOXIN 2; MITOCHONDRIAL PROTEIN; THIOREDOXIN; TXN2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; MICROGLIA; NITROSYLATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; RAT; TUMOR GROWTH; ANIMAL; CELL MOTION; DISEASE MODEL; ENZYME ACTIVATION; GENE KNOCKDOWN; GENETICS; IMMUNOLOGY; MALE; METABOLISM; MITOCHONDRION; MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME; XENOGRAFT;

ANIMALS; CASPASE 3; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HETEROGRAFTS; HUMANS; MALE; MICE; MICROGLIA; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NITRIC OXIDE SYNTHASE TYPE II; PHENOTYPE; THIOREDOXINS; TUMOR BURDEN;

EID: 84987621365     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3545     Document Type: Article

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