Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

Nature Neuroscience

Volumn 21, Issue 4, 2018, Pages 541-551

  Ajami, Bahareh ^a   Samusik, Nikolay ^a   Wieghofer, Peter ^b,c   Ho, Peggy P ^a   Crotti, Andrea ^d   Bjornson, Zach ^a   Prinz, Marco ^b   Fantl, Wendy J ^a   Nolan, Garry P ^a   Steinman, Lawrence ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA5 INTEGRIN; BONE MARROW STROMAL ANTIGEN 2; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CD11B ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; KI 67 ANTIGEN; RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASE C; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; CHEMOKINE RECEPTOR CX3CR1; COPPER ZINC SUPEROXIDE DISMUTASE; CX3CR1 PROTEIN, MOUSE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYTOKINE; HTT PROTEIN, MOUSE; HUNTINGTIN; PHOTOPROTEIN; SIGNAL PEPTIDE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN MYELOID CELL; CELL ACTIVATION; CELL EXPANSION; CELL INFILTRATION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUNTINGTON CHOREA; MASS CYTOMETRY; MOLECULARLY TARGETED THERAPY; MOUSE; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; UPREGULATION; ANIMAL; BONE MARROW CELL; BRAIN; C57BL MOUSE; DISEASE MODEL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; METABOLISM; MONOCYTE; MUTANT MOUSE STRAIN; MUTATION; PATHOLOGY; PROCEDURES; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CREB-BINDING PROTEIN; CX3C CHEMOKINE RECEPTOR 1; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MONOCYTES; MUTATION; MYELOID CELLS; SINGLE-CELL ANALYSIS; SUPEROXIDE DISMUTASE-1;

EID: 85042882147     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/s41593-018-0100-x     Document Type: Article

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