-
1
-
-
84940769248
-
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
-
Toledo, J. B. et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain 138, 2701-2715 (2015).
-
(2015)
Brain
, vol.138
, pp. 2701-2715
-
-
Toledo, J.B.1
-
2
-
-
84925880097
-
2015 Alzheimer's disease facts and figures
-
Alzheimer's Association
-
Alzheimer's Association. 2015 Alzheimer's disease facts and figures. Alzheimers Dement. 11, 332-384 (2015).
-
(2015)
Alzheimers Dement
, vol.11
, pp. 332-384
-
-
-
3
-
-
84981340960
-
Epigenetic mechanisms of longevity and aging
-
Sen, P., Shah, P. P., Nativio, R. & Berger, S. L. Epigenetic mechanisms of longevity and aging. Cell 166, 822-839 (2016).
-
(2016)
Cell
, vol.166
, pp. 822-839
-
-
Sen, P.1
Shah, P.P.2
Nativio, R.3
Berger, S.L.4
-
4
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara, T. L. et al. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell 136, 62-74 (2009).
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
-
5
-
-
84872601036
-
Histone acetylation: Molecular mnemonics on the chromatin
-
Gräff, J. & Tsai, L. H. Histone acetylation: molecular mnemonics on the chromatin. Nat. Rev. Neurosci. 14, 97-111 (2013).
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 97-111
-
-
Gräff, J.1
Tsai, L.H.2
-
6
-
-
33747186161
-
Chromatin immunoprecipitation in postmortem brain
-
Huang, H. S., Matevossian, A., Jiang, Y. & Akbarian, S. Chromatin immunoprecipitation in postmortem brain. J. Neurosci. Methods 156, 284-292 (2006).
-
(2006)
J. Neurosci. Methods
, vol.156
, pp. 284-292
-
-
Huang, H.S.1
Matevossian, A.2
Jiang, Y.3
Akbarian, S.4
-
7
-
-
22244460464
-
Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain
-
Stadler, F. et al. Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain. J. Neurochem. 94, 324-336 (2005).
-
(2005)
J. Neurochem.
, vol.94
, pp. 324-336
-
-
Stadler, F.1
-
8
-
-
84931023395
-
Effects of postmortem interval on biomolecule integrity in the brain
-
Nagy, C. et al. Effects of postmortem interval on biomolecule integrity in the brain. J. Neuropathol. Exp. Neurol. 74, 459-469 (2015).
-
(2015)
J. Neuropathol. Exp. Neurol.
, vol.74
, pp. 459-469
-
-
Nagy, C.1
-
9
-
-
80055106172
-
A chromatin assay for human brain tissue
-
Matevossian, A. & Akbarian, S. A chromatin assay for human brain tissue. J. Vis. Exp. 13, 717 (2008).
-
(2008)
J. Vis. Exp.
, vol.13
, pp. 717
-
-
Matevossian, A.1
Akbarian, S.2
-
10
-
-
84919844313
-
Epigenomics of Alzheimer's disease
-
Bennett, D. A. et al. Epigenomics of Alzheimer's disease. Transl. Res. 165, 200-220 (2015).
-
(2015)
Transl. Res.
, vol.165
, pp. 200-220
-
-
Bennett, D.A.1
-
11
-
-
77952715009
-
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex
-
Cheung, I. et al. Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc. Natl Acad. Sci. USA 107, 8824-8829 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 8824-8829
-
-
Cheung, I.1
-
12
-
-
79955583858
-
Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol
-
Zhou, Z., Yuan, Q., Mash, D. C. & Goldman, D. Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol. Proc. Natl Acad. Sci. USA 108, 6626-6631 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 6626-6631
-
-
Zhou, Z.1
Yuan, Q.2
Mash, D.C.3
Goldman, D.4
-
13
-
-
32444434989
-
Histone H4-K16 acetylation controls chromatin structure and protein interactions
-
Shogren-Knaak, M. et al. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311, 844-847 (2006).
-
(2006)
Science
, vol.311
, pp. 844-847
-
-
Shogren-Knaak, M.1
-
14
-
-
0033866836
-
Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila
-
Akhtar, A. & Becker, P. B. Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila. Mol. Cell 5, 367-375 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 367-375
-
-
Akhtar, A.1
Becker, P.B.2
-
15
-
-
84922374664
-
TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity
-
Sammons, M. A., Zhu, J., Drake, A. M. & Berger, S. L. TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity. Genome Res. 25, 179-188 (2015).
-
(2015)
Genome Res.
, vol.25
, pp. 179-188
-
-
Sammons, M.A.1
Zhu, J.2
Drake, A.M.3
Berger, S.L.4
-
16
-
-
77954360144
-
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
-
Sharma, G. G. et al. MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol. Cell. Biol. 30, 3582-3595 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3582-3595
-
-
Sharma, G.G.1
-
17
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular lifespan
-
Dang, W. et al. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459, 802-807 (2009).
-
(2009)
Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
-
18
-
-
75649086193
-
Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction
-
Kozak, M. L. et al. Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J. 29, 158-170 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 158-170
-
-
Kozak, M.L.1
-
19
-
-
84918515620
-
HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
-
Rai, T. S. et al. HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia. Genes Dev. 28, 2712-2725 (2014).
-
(2014)
Genes Dev.
, vol.28
, pp. 2712-2725
-
-
Rai, T.S.1
-
20
-
-
84890899433
-
H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction
-
Taylor, G. C., Eskeland, R., Hekimoglu-Balkan, B., Pradeepa, M. M. & Bickmore, W. A. H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction. Genome Res. 23, 2053-2065 (2013).
-
(2013)
Genome Res
, vol.23
, pp. 2053-2065
-
-
Taylor, G.C.1
Eskeland, R.2
Hekimoglu-Balkan, B.3
Pradeepa, M.M.4
Bickmore, W.A.5
-
21
-
-
80052099172
-
Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease
-
Blalock, E. M., Buechel, H. M., Popovic, J., Geddes, J. W. & Landfield, P. W. Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease. J. Chem. Neuroanat. 42, 118-126 (2011).
-
(2011)
J. Chem. Neuroanat.
, vol.42
, pp. 118-126
-
-
Blalock, E.M.1
Buechel, H.M.2
Popovic, J.3
Geddes, J.W.4
Landfield, P.W.5
-
22
-
-
3042631024
-
Gene regulation and DNA damage in the ageing human brain
-
Lu, T. et al. Gene regulation and DNA damage in the ageing human brain. Nature 429, 883-891 (2004).
-
(2004)
Nature
, vol.429
, pp. 883-891
-
-
Lu, T.1
-
23
-
-
0000847978
-
Gene-expression profile of the ageing brain in mice
-
Lee, C. K., Weindruch, R. & Prolla, T. A. Gene-expression profile of the ageing brain in mice. Nat. Genet. 25, 294-297 (2000).
-
(2000)
Nat. Genet.
, vol.25
, pp. 294-297
-
-
Lee, C.K.1
Weindruch, R.2
Prolla, T.A.3
-
24
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
Chen, Q. & Ames, B. N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc. Natl Acad. Sci. USA 91, 4130-4134 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
25
-
-
10944257464
-
Human cell senescence as a DNA damage response
-
von Zglinicki, T., Saretzki, G., Ladhoff, J., d'Adda di Fagagna, F. & Jackson, S. P. Human cell senescence as a DNA damage response. Mech. Ageing Dev. 126, 111-117 (2005).
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 111-117
-
-
Von Zglinicki, T.1
Saretzki, G.2
Ladhoff, J.3
D'Adda Di Fagagna, F.4
Jackson, S.P.5
-
26
-
-
84929921146
-
Immune attack: The role of inflammation in Alzheimer disease
-
Heppner, F. L., Ransohoff, R. M. & Becher, B. Immune attack: The role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 16, 358-372 (2015).
-
(2015)
Nat. Rev. Neurosci.
, vol.16
, pp. 358-372
-
-
Heppner, F.L.1
Ransohoff, R.M.2
Becher, B.3
-
27
-
-
84896828867
-
Wnt signaling in the nervous system and in Alzheimer's disease
-
Inestrosa, N. C. & Varela-Nallar, L. Wnt signaling in the nervous system and in Alzheimer's disease. J. Mol. Cell Biol. 6, 64-74 (2014).
-
(2014)
J. Mol. Cell Biol.
, vol.6
, pp. 64-74
-
-
Inestrosa, N.C.1
Varela-Nallar, L.2
-
28
-
-
84901760036
-
The role of Wnt signaling in the development of Alzheimer's disease: A potential therapeutic target
-
Wan, W., Xia, S., Kalionis, B., Liu, L. & Li, Y. The role of Wnt signaling in the development of Alzheimer's disease: A potential therapeutic target BioMed Res. Int. 2014, 301575 (2014).
-
(2014)
BioMed Res. Int.
, vol.2014
, pp. 301575
-
-
Wan, W.1
Xia, S.2
Kalionis, B.3
Liu, L.4
Li, Y.5
-
29
-
-
85020754168
-
Activation of Ras-ERK signaling and GSK-3 by amyloid precursor protein and amyloid beta facilitates neurodegeneration in Alzheimer's disease
-
Kirouac, L., Rajic, A. J., Cribbs, D. H. & Padmanabhan, J. Activation of Ras-ERK signaling and GSK-3 by amyloid precursor protein and amyloid beta facilitates neurodegeneration in Alzheimer's disease. eNeuro https://doi. org/10. 1523/ENEURO. 0149-16. 2017 (2017).
-
(2017)
ENeuro
-
-
Kirouac, L.1
Rajic, A.J.2
Cribbs, D.H.3
Padmanabhan, J.4
-
30
-
-
84892377524
-
Trafficking regulation of proteins in Alzheimer's disease
-
Jiang, S. et al. Trafficking regulation of proteins in Alzheimer's disease. Mol. Neurodegener. 9, 6 (2014).
-
(2014)
Mol. Neurodegener.
, vol.9
, pp. 6
-
-
Jiang, S.1
-
31
-
-
80052022462
-
Cistrome: An integrative platform for transcriptional regulation studies
-
Liu, T. et al Cistrome: An integrative platform for transcriptional regulation studies. Genome Biol. 12, R83 (2011).
-
(2011)
Genome Biol
, vol.12
, pp. R83
-
-
Liu, T.1
-
32
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong, J. A. et al. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957 (1995).
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
-
33
-
-
84897386660
-
REST and stress resistance in ageing and Alzheimer's disease
-
Lu, T. et al. REST and stress resistance in ageing and Alzheimer's disease. Nature 507, 448-454 (2014).
-
(2014)
Nature
, vol.507
, pp. 448-454
-
-
Lu, T.1
-
34
-
-
1242341923
-
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
-
Blalock, E. M. et al. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc. Natl Acad. Sci. USA 101, 2173-2178 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2173-2178
-
-
Blalock, E.M.1
-
35
-
-
0032582854
-
CCAAT-enhancer binding protein alpha is expressed in activated microglial cells after brain injury
-
Walton, M. et al. CCAAT-enhancer binding protein alpha is expressed in activated microglial cells after brain injury. Brain Res. Mol. Brain Res. 61, 11-22 (1998).
-
(1998)
Brain Res. Mol. Brain Res.
, vol.61
, pp. 11-22
-
-
Walton, M.1
-
36
-
-
27544434763
-
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
-
Chen, W. Y. et al. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 123, 437-448 (2005).
-
(2005)
Cell
, vol.123
, pp. 437-448
-
-
Chen, W.Y.1
-
37
-
-
33745744942
-
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies
-
Valenta, T., Lukas, J., Doubravska, L., Fafilek, B. & Korinek, V. HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. EMBO J. 25, 2326-2337 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 2326-2337
-
-
Valenta, T.1
Lukas, J.2
Doubravska, L.3
Fafilek, B.4
Korinek, V.5
-
38
-
-
84908568670
-
Plasticity of the aging brain: New directions in cognitive neuroscience
-
Gutchess, A. Plasticity of the aging brain: new directions in cognitive neuroscience. Science 346, 579-582 (2014).
-
(2014)
Science
, vol.346
, pp. 579-582
-
-
Gutchess, A.1
-
39
-
-
84856346453
-
Plasticity in early Alzheimer's disease: An opportunity for intervention
-
Hill, N. L., Kolanowski, A. M. & Gill, D. J. Plasticity in early Alzheimer's disease: An opportunity for intervention. Top. Geriatr. Rehabil. 27, 257-267 (2011).
-
(2011)
Top. Geriatr. Rehabil.
, vol.27
, pp. 257-267
-
-
Hill, N.L.1
Kolanowski, A.M.2
Gill, D.J.3
-
40
-
-
0035690720
-
Glial activation in Alzheimer's disease: The role of Abeta and its associated proteins
-
Meda, L., Baron, P. & Scarlato, G. Glial activation in Alzheimer's disease: The role of Abeta and its associated proteins. Neurobiol. Aging 22, 885-893 (2001).
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 885-893
-
-
Meda, L.1
Baron, P.2
Scarlato, G.3
-
41
-
-
84888317489
-
Meta-analysis of 74, 046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert, J. C. et al. Meta-analysis of 74, 046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 45, 1452-1458 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
-
43
-
-
84864066707
-
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants
-
Zou, F. et al. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet. 8, e1002707 (2012).
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002707
-
-
Zou, F.1
-
44
-
-
84939517308
-
GREGOR: Evaluating global enrichment of traitassociated variants in epigenomic features using a systematic, data-driven approach
-
Schmidt, E. M. et al. GREGOR: evaluating global enrichment of traitassociated variants in epigenomic features using a systematic, data-driven approach. Bioinformatics 31, 2601-2606 (2015).
-
(2015)
Bioinformatics
, vol.31
, pp. 2601-2606
-
-
Schmidt, E.M.1
-
45
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
GTEx Consortium
-
GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 45, 580-585 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 580-585
-
-
-
46
-
-
84865419712
-
Deacetylation of H4-K16Ac and heterochromatin assembly in senescence
-
Contrepois, K., Thuret, J. Y., Courbeyrette, R., Fenaille, F. & Mann, C. Deacetylation of H4-K16Ac and heterochromatin assembly in senescence. Epigenetics Chromatin 5, 15 (2012).
-
(2012)
Epigenetics Chromatin
, vol.5
, pp. 15
-
-
Contrepois, K.1
Thuret, J.Y.2
Courbeyrette, R.3
Fenaille, F.4
Mann, C.5
-
47
-
-
84925259513
-
SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence
-
Wan, Y. Z. et al. SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence. Aging Cell 13, 890-899 (2014).
-
(2014)
Aging Cell
, vol.13
, pp. 890-899
-
-
Wan, Y.Z.1
-
48
-
-
79961083402
-
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
-
Krishnan, V. et al. Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice. Proc. Natl Acad. Sci. USA 108, 12325-12330 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 12325-12330
-
-
Krishnan, V.1
-
49
-
-
84862777943
-
An epigenetic blockade of cognitive functions in the neurodegenerating brain
-
Gräff, J. et al. An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483, 222-226 (2012).
-
(2012)
Nature
, vol.483
, pp. 222-226
-
-
Gräff, J.1
-
50
-
-
84860863375
-
Targeted proteomics for quantification of histone acetylation in Alzheimer's disease
-
Zhang, K. et al. Targeted proteomics for quantification of histone acetylation in Alzheimer's disease. Proteomics 12, 1261-1268 (2012).
-
(2012)
Proteomics
, vol.12
, pp. 1261-1268
-
-
Zhang, K.1
-
51
-
-
84903689436
-
A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank
-
Toledo, J. B. et al. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimer's Dement. 10, 477-484 (2014).
-
(2014)
Alzheimer's Dement
, vol.10
, pp. 477-484
-
-
Toledo, J.B.1
-
52
-
-
0030700593
-
The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: A commentary
-
Mirra, S. S. The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: A commentary. Neurobiol. Aging 18 Suppl, S91-S94 (1997).
-
(1997)
Neurobiol. Aging
, vol.18
, pp. S91-S94
-
-
Mirra, S.S.1
-
53
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak, H., Alafuzoff, I., Arzberger, T., Kretzschmar, H. & Del Tredici, K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol. 112, 389-404 (2006).
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
54
-
-
84866316014
-
Astrocyte senescence as a component of Alzheimer's disease
-
Bhat, R. et al. Astrocyte senescence as a component of Alzheimer's disease. PLoS ONE 7, e45069 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e45069
-
-
Bhat, R.1
-
55
-
-
84941243900
-
Subset of early radial glial progenitors that contribute to the development of callosal neurons is absent from avian brain
-
García-Moreno, F. & Molnár, Z. Subset of early radial glial progenitors that contribute to the development of callosal neurons is absent from avian brain. Proc. Natl Acad. Sci. USA 112, E5058-E5067 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E5058-E5067
-
-
García-Moreno, F.1
Molnár, Z.2
-
56
-
-
28044434180
-
Neural connectivity and cortical substrates of cognition in hominoids
-
Schenker, N. M., Desgouttes, A. M. & Semendeferi, K. Neural connectivity and cortical substrates of cognition in hominoids. J. Hum. Evol. 49, 547-569 (2005).
-
(2005)
J. Hum. Evol.
, vol.49
, pp. 547-569
-
-
Schenker, N.M.1
Desgouttes, A.M.2
Semendeferi, K.3
-
57
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
Salzberg, S.L.2
-
58
-
-
53849146020
-
Model-based analysis of ChIP-Seq aMACSa
-
Zhang, Y. et al. Model-based analysis of ChIP-Seq aMACSa. Genome Biol 9, R137 (2008).
-
(2008)
Genome Biol
, vol.9
, pp. R137
-
-
Zhang, Y.1
-
59
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen, X. et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133, 1106-1117 (2008).
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
-
60
-
-
85025075807
-
KMT2A and KMT2B mediate memory function by affecting distinct genomic regions
-
Kerimoglu, C. et al. KMT2A and KMT2B mediate memory function by affecting distinct genomic regions. Cell Rep. 20, 538-548 (2017).
-
(2017)
Cell Rep.
, vol.20
, pp. 538-548
-
-
Kerimoglu, C.1
-
61
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009).
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
62
-
-
84863987483
-
INRICH: Interval-based enrichment analysis for genome-wide association studies
-
Lee, P. H., O'Dushlaine, C., Thomas, B. & Purcell, S. M. INRICH: interval-based enrichment analysis for genome-wide association studies. Bioinformatics 28, 1797-1799 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 1797-1799
-
-
Lee, P.H.1
O'Dushlaine, C.2
Thomas, B.3
Purcell, S.M.4
-
63
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
64
-
-
80054993342
-
Spatio-temporal transcriptome of the human brain
-
Kang, H. J. et al. Spatio-temporal transcriptome of the human brain. Nature 478, 483-489 (2011).
-
(2011)
Nature
, vol.478
, pp. 483-489
-
-
Kang, H.J.1
-
65
-
-
0036079158
-
The human genome browser at UCSC
-
Kent, W. J. et al. The human genome browser at UCSC. Genome Res. 12, 996-1006 (2002).
-
(2002)
Genome Res.
, vol.12
, pp. 996-1006
-
-
Kent, W.J.1
-
66
-
-
77951770756
-
BEDTools: A flexible suite of utilities for comparing genomic features
-
Quinlan, A. R. & Hall, I. M. BEDTools: A flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841-842 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 841-842
-
-
Quinlan, A.R.1
Hall, I.M.2
-
67
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
68
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
69
-
-
84943171338
-
A global reference for human genetic variation
-
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68-74 (2015).
-
(2015)
Nature
, vol.526
, pp. 68-74
-
-
Auton, A.1
-
70
-
-
84959157387
-
Epigenomic annotation of gene regulatory alterations during evolution of the primate brain
-
Vermunt, M. W. et al. Epigenomic annotation of gene regulatory alterations during evolution of the primate brain. Nat. Neurosci. 19, 494-503 (2016).
-
(2016)
Nat. Neurosci.
, vol.19
, pp. 494-503
-
-
Vermunt, M.W.1
-
71
-
-
84953924597
-
Insulator dysfunction and oncogene activation in IDH mutant gliomas
-
Flavahan, W. A. et al. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature 529, 110-114 (2016).
-
(2016)
Nature
, vol.529
, pp. 110-114
-
-
Flavahan, W.A.1
|