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Volumn 271, Issue , 2018, Pages 148-155

Treatment with omega-3 polyunsaturated fatty acids does not improve endothelial function in patients with type 2 diabetes and very high cardiovascular risk: A randomized, double-blind, placebo-controlled study (Omega-FMD)

Author keywords

Atherosclerosis; Cardiovascular disease; Flow mediated dilation; Omega 3 polyunsaturated fatty acids; Type 2 diabetes

Indexed keywords

ACETYLSALICYLIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOCOSAHEXAENOIC ACID; FATTY ACID; GLYCERYL TRINITRATE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ICOSAPENTAENOIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; PLACEBO; TRIACYLGLYCEROL;

EID: 85042851809     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2018.02.030     Document Type: Article
Times cited : (35)

References (49)
  • 1
    • 80054109997 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice The Sixth Joint Task Force of the European Society of Cardiology 2016:2315–2381. doi:10.1093/eurheartj/ehw106.
    • Prevention C, Eacpr R, Hoes AW, Ireland MC, Corra U, Uk CD, et al. 2016 European guidelines on cardiovascular disease prevention in clinical practice The Sixth Joint Task Force of the European Society of Cardiology 2016:2315–2381. doi:10.1093/eurheartj/ehw106.
    • (2016)
    • Prevention, C.1    Eacpr, R.2    Hoes, A.W.3    Ireland, M.C.4    Corra, U.5    Uk, C.D.6
  • 2
    • 84857989465 scopus 로고    scopus 로고
    • Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies
    • Zheng, J., Huang, T., Yu, Y., Hu, X., Yang, B., Li, D., Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies. Publ. Health Nutr. 15 (2012), 725–737.
    • (2012) Publ. Health Nutr. , vol.15 , pp. 725-737
    • Zheng, J.1    Huang, T.2    Yu, Y.3    Hu, X.4    Yang, B.5    Li, D.6
  • 3
    • 77951492246 scopus 로고    scopus 로고
    • Marine (n-3) fatty acids, fish consumption, and the 10-year risk of fatal and nonfatal coronary heart disease in a large population of Dutch adults with low fish intake
    • de Goede, J., Geleijnse, J.M., Boer, J.M.A., Kromhout, D., Verschuren, W.M.M., Marine (n-3) fatty acids, fish consumption, and the 10-year risk of fatal and nonfatal coronary heart disease in a large population of Dutch adults with low fish intake. J. Nutr. 140 (2010), 1023–1028.
    • (2010) J. Nutr. , vol.140 , pp. 1023-1028
    • de Goede, J.1    Geleijnse, J.M.2    Boer, J.M.A.3    Kromhout, D.4    Verschuren, W.M.M.5
  • 5
    • 0037051975 scopus 로고    scopus 로고
    • Fish and omega-3 fatty acid intake and risk of coronary heart disease in women
    • Hu, F.B., Bronner, L., Willett, W.C., Stampfer, M.J., Rexrode, K.M., Albert, C.M., et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. Jama 287 (2002), 1815–1821.
    • (2002) Jama , vol.287 , pp. 1815-1821
    • Hu, F.B.1    Bronner, L.2    Willett, W.C.3    Stampfer, M.J.4    Rexrode, K.M.5    Albert, C.M.6
  • 6
    • 77950555307 scopus 로고    scopus 로고
    • Effects of polyunsaturated omega-3 fatty acids on responsiveness to dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: the OMEGA-PCI (OMEGA-3 fatty acids after pci to modify responsiveness to dual antiplatelet therapy) st
    • Gajos, G., Rostoff, P., Undas, A., Piwowarska, W., Effects of polyunsaturated omega-3 fatty acids on responsiveness to dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: the OMEGA-PCI (OMEGA-3 fatty acids after pci to modify responsiveness to dual antiplatelet therapy) st. J. Am. Coll. Cardiol. 55 (2010), 1671–1678, 10.1016/j.jacc.2009.11.080.
    • (2010) J. Am. Coll. Cardiol. , vol.55 , pp. 1671-1678
    • Gajos, G.1    Rostoff, P.2    Undas, A.3    Piwowarska, W.4
  • 7
    • 84897084759 scopus 로고    scopus 로고
    • Polyunsaturated omega-3 fatty acids reduce lipoprotein-associated phospholipase A2 in patients with stable angina
    • Gajos, G., Zalewski, J., Mostowik, M., Konduracka, E., Nessler, J., Undas, A., Polyunsaturated omega-3 fatty acids reduce lipoprotein-associated phospholipase A2 in patients with stable angina. Nutr. Metabol. Cardiovasc. Dis. 24 (2014), 434–439, 10.1016/j.numecd.2013.09.011.
    • (2014) Nutr. Metabol. Cardiovasc. Dis. , vol.24 , pp. 434-439
    • Gajos, G.1    Zalewski, J.2    Mostowik, M.3    Konduracka, E.4    Nessler, J.5    Undas, A.6
  • 8
    • 84880252433 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids increase plasma adiponectin to leptin ratio in stable coronary artery disease
    • Mostowik, M., Gajos, G., Zalewski, J., Nessler, J., Undas, A., Omega-3 polyunsaturated fatty acids increase plasma adiponectin to leptin ratio in stable coronary artery disease. Cardiovasc. Drugs Ther. 27 (2013), 289–295, 10.1007/s10557-013-6457-x.
    • (2013) Cardiovasc. Drugs Ther. , vol.27 , pp. 289-295
    • Mostowik, M.1    Gajos, G.2    Zalewski, J.3    Nessler, J.4    Undas, A.5
  • 9
    • 79959760769 scopus 로고    scopus 로고
    • Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturated omega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (OMEGA-PCI Clot)
    • Gajos, G., Zalewski, J., Rostoff, P., Nessler, J., Piwowarska, W., Undas, A., Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturated omega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (OMEGA-PCI Clot). Arterioscler. Thromb. Vasc. Biol. 31 (2011), 1696–1702, 10.1161/ATVBAHA.111.228593.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1696-1702
    • Gajos, G.1    Zalewski, J.2    Rostoff, P.3    Nessler, J.4    Piwowarska, W.5    Undas, A.6
  • 10
    • 85015204246 scopus 로고    scopus 로고
    • Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease
    • Advisory, A.H.A.S., Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease. 2017, 10.1161/CIR.0000000000000482.
    • (2017)
    • Advisory, A.H.A.S.1
  • 13
    • 85021818218 scopus 로고    scopus 로고
    • Association of Carotid Intima – Media Thickness and Plaques with Diabetic Microvascular Complications: Still Much to Learn
    • C.R.L. Cardoso, G.F. Salles, Association of Carotid Intima – Media Thickness and Plaques with Diabetic Microvascular Complications: Still Much to Learn, (2017) 390–391. https://doi.org/10.3390/ijms17.
    • (2017) , pp. 390-391
    • Cardoso, C.R.L.1    Salles, G.F.2
  • 15
    • 85019382215 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein is an independent marker of abnormal coronary vasoreactivity in patients with non-obstructive coronary artery disease
    • Sara, J.D.S., Prasad, M., Zhang, M., Lennon, R.J., Herrmann, J., Lerman, L.O., et al. High-sensitivity C-reactive protein is an independent marker of abnormal coronary vasoreactivity in patients with non-obstructive coronary artery disease. Am. Heart J. 190 (2017), 1–11.
    • (2017) Am. Heart J. , vol.190 , pp. 1-11
    • Sara, J.D.S.1    Prasad, M.2    Zhang, M.3    Lennon, R.J.4    Herrmann, J.5    Lerman, L.O.6
  • 16
    • 84991523162 scopus 로고    scopus 로고
    • Prognostic value of flow-mediated vasodilation in brachial artery and fingertip artery for cardiovascular events: a systematic review and meta-analysis
    • Matsuzawa, Y., Kwon, T.G., Lennon, R.J., Lerman, L.O., Lerman, A., Prognostic value of flow-mediated vasodilation in brachial artery and fingertip artery for cardiovascular events: a systematic review and meta-analysis. J. Am. Heart Assoc., 2015, 4, 10.1161/JAHA.115.002270.
    • (2015) J. Am. Heart Assoc. , pp. 4
    • Matsuzawa, Y.1    Kwon, T.G.2    Lennon, R.J.3    Lerman, L.O.4    Lerman, A.5
  • 17
    • 85032584193 scopus 로고    scopus 로고
    • Endothelial function assessed by automatic measurement of enclosed zone flow-mediated vasodilation using an oscillometric method is an independent predictor of cardiovascular events
    • Morimoto, H., Kajikawa, M., Oda, N., Idei, N., Hirano, H., Hida, E., et al. Endothelial function assessed by automatic measurement of enclosed zone flow-mediated vasodilation using an oscillometric method is an independent predictor of cardiovascular events. J. Am. Heart Assoc. 5 (2016), 1–10, 10.1161/JAHA.116.004385.
    • (2016) J. Am. Heart Assoc. , vol.5 , pp. 1-10
    • Morimoto, H.1    Kajikawa, M.2    Oda, N.3    Idei, N.4    Hirano, H.5    Hida, E.6
  • 18
    • 79959788211 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes: the role of reparatory mechanisms
    • Avogaro, A., Albiero, M., Menegazzo, L., De Kreutzenberg, S., Fadini, G.P., Endothelial dysfunction in diabetes: the role of reparatory mechanisms. Diabetes Care 34 (2011), 285–290, 10.2337/dc11-s239.
    • (2011) Diabetes Care , vol.34 , pp. 285-290
    • Avogaro, A.1    Albiero, M.2    Menegazzo, L.3    De Kreutzenberg, S.4    Fadini, G.P.5
  • 19
    • 77957933610 scopus 로고    scopus 로고
    • Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis
    • Inaba, Y., Chen, J.A., Bergmann, S.R., Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int. J. Cardiovasc. Imag. 26 (2010), 631–640.
    • (2010) Int. J. Cardiovasc. Imag. , vol.26 , pp. 631-640
    • Inaba, Y.1    Chen, J.A.2    Bergmann, S.R.3
  • 20
    • 68949144593 scopus 로고    scopus 로고
    • Vascular endothelial function predicts mortality risk in patients with advanced ischaemic chronic heart failure
    • Shechter, M., Matetzky, S., Arad, M., Feinberg, M.S., Freimark, D., Vascular endothelial function predicts mortality risk in patients with advanced ischaemic chronic heart failure. Eur. J. Heart Fail. 11 (2009), 588–593.
    • (2009) Eur. J. Heart Fail. , vol.11 , pp. 588-593
    • Shechter, M.1    Matetzky, S.2    Arad, M.3    Feinberg, M.S.4    Freimark, D.5
  • 21
    • 84883790321 scopus 로고    scopus 로고
    • Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis
    • Ras, R.T., Streppel, M.T., Draijer, R., Zock, P.L., Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis. Int. J. Cardiol. 168 (2013), 344–351.
    • (2013) Int. J. Cardiol. , vol.168 , pp. 344-351
    • Ras, R.T.1    Streppel, M.T.2    Draijer, R.3    Zock, P.L.4
  • 22
    • 79451469852 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids early supplementation improves ultrasound indices of endothelial function, but not through NO inhibitors in patients with acute myocardial infarction: N-3 PUFA supplementation in acute myocardial infarction
    • Haberka, M., Mizia-Stec, K., Mizia, M., Janowska, J., Gieszczyk, K., Chmiel, A., et al. N-3 polyunsaturated fatty acids early supplementation improves ultrasound indices of endothelial function, but not through NO inhibitors in patients with acute myocardial infarction: N-3 PUFA supplementation in acute myocardial infarction. Clin. Nutr. 30 (2011), 79–85, 10.1016/j.clnu.2010.07.011.
    • (2011) Clin. Nutr. , vol.30 , pp. 79-85
    • Haberka, M.1    Mizia-Stec, K.2    Mizia, M.3    Janowska, J.4    Gieszczyk, K.5    Chmiel, A.6
  • 23
    • 70349410386 scopus 로고    scopus 로고
    • Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes
    • Rizza, S., Tesauro, M., Cardillo, C., Galli, A., Iantorno, M., Gigli, F., et al. Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes. Atherosclerosis 206 (2009), 569–574.
    • (2009) Atherosclerosis , vol.206 , pp. 569-574
    • Rizza, S.1    Tesauro, M.2    Cardillo, C.3    Galli, A.4    Iantorno, M.5    Gigli, F.6
  • 24
    • 41349089494 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acid in peripheral arterial disease: effect on lipid pattern, disease severity, inflammation profile, and endothelial function
    • Schiano, V., Laurenzano, E., Brevetti, G., De Maio, J.I., Lanero, S., Scopacasa, F., et al. Omega-3 polyunsaturated fatty acid in peripheral arterial disease: effect on lipid pattern, disease severity, inflammation profile, and endothelial function. Clin. Nutr. 27 (2008), 241–247.
    • (2008) Clin. Nutr. , vol.27 , pp. 241-247
    • Schiano, V.1    Laurenzano, E.2    Brevetti, G.3    De Maio, J.I.4    Lanero, S.5    Scopacasa, F.6
  • 26
    • 84862829128 scopus 로고    scopus 로고
    • Effect of omega-3 fatty acids supplementation on endothelial function: a meta-analysis of randomized controlled trials
    • Wang, Q., Liang, X., Wang, L., Lu, X., Huang, J., Cao, J., et al. Effect of omega-3 fatty acids supplementation on endothelial function: a meta-analysis of randomized controlled trials. Atherosclerosis 221 (2012), 536–543, 10.1016/j.atherosclerosis.2012.01.006.
    • (2012) Atherosclerosis , vol.221 , pp. 536-543
    • Wang, Q.1    Liang, X.2    Wang, L.3    Lu, X.4    Huang, J.5    Cao, J.6
  • 27
    • 85018464511 scopus 로고    scopus 로고
    • Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or inflammation in patients with atherosclerosis and type 2 diabetes
    • Poreba, M., Mostowik, M., Siniarski, A., Golebiowska-Wiatrak, R., Malinowski, K.P., Haberka, M., et al. Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or inflammation in patients with atherosclerosis and type 2 diabetes. Cardiovasc. Diabetol., 16, 2017, 50, 10.1186/s12933-017-0523-9.
    • (2017) Cardiovasc. Diabetol. , vol.16 , pp. 50
    • Poreba, M.1    Mostowik, M.2    Siniarski, A.3    Golebiowska-Wiatrak, R.4    Malinowski, K.P.5    Haberka, M.6
  • 28
    • 0037116573 scopus 로고    scopus 로고
    • Guidelines for the ultrasound assessment of endothelial-dependent flow- mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force
    • Corretti, M.C., Anderson, T.J., Benjamin, E.J., Celermajer, D., Charbonneau, F., Creager, M a, et al. Guidelines for the ultrasound assessment of endothelial-dependent flow- mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J. Am. Coll. Cardiol. 39 (2002), 257–265.
    • (2002) J. Am. Coll. Cardiol. , vol.39 , pp. 257-265
    • Corretti, M.C.1    Anderson, T.J.2    Benjamin, E.J.3    Celermajer, D.4    Charbonneau, F.5    Creager, M.A.6
  • 29
    • 0031575846 scopus 로고    scopus 로고
    • Eicosapentaenoic acid enhances nitric oxide production by cultured human endothelial cells
    • Okuda, Y., Kawashima, K., Sawada, T., Tsurumaru, K., Asano, M., Suzuki, S., et al. Eicosapentaenoic acid enhances nitric oxide production by cultured human endothelial cells. Biochem. Biophys. Res. Commun. 232 (1997), 487–491, 10.1006/bbrc.1997.6328.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 487-491
    • Okuda, Y.1    Kawashima, K.2    Sawada, T.3    Tsurumaru, K.4    Asano, M.5    Suzuki, S.6
  • 30
    • 84882336972 scopus 로고    scopus 로고
    • Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I
    • Paneni, F., Beckman, J.A., Creager, M.A., Cosentino, F., Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Eur. Heart J. 34 (2013), 2436–2443.
    • (2013) Eur. Heart J. , vol.34 , pp. 2436-2443
    • Paneni, F.1    Beckman, J.A.2    Creager, M.A.3    Cosentino, F.4
  • 31
    • 79960959816 scopus 로고    scopus 로고
    • Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials
    • d4169
    • Boussageon, R., Bejan-Angoulvant, T., Saadatian-Elahi, M., Lafont, S., Bergeonneau, C., Kassai, B., et al. Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials. BMJ, 343, 2011, 10.1136/bmj.d4169 d4169.
    • (2011) BMJ , vol.343
    • Boussageon, R.1    Bejan-Angoulvant, T.2    Saadatian-Elahi, M.3    Lafont, S.4    Bergeonneau, C.5    Kassai, B.6
  • 33
    • 84877766193 scopus 로고    scopus 로고
    • Hyperglycemia and vascular metabolic memory: truth or fiction?
    • Bianchi, C., Miccoli, R., Del Prato, S., Hyperglycemia and vascular metabolic memory: truth or fiction?. Curr. Diabetes Rep. 13 (2013), 403–410.
    • (2013) Curr. Diabetes Rep. , vol.13 , pp. 403-410
    • Bianchi, C.1    Miccoli, R.2    Del Prato, S.3
  • 34
    • 0034006247 scopus 로고    scopus 로고
    • Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia
    • Goodfellow, J., Bellamy, M.F., Ramsey, M.W., Jones, C.J.H., Lewis, M.J., Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J. Am. Coll. Cardiol. 35 (2000), 265–270, 10.1016/S0735-1097(99)00548-3.
    • (2000) J. Am. Coll. Cardiol. , vol.35 , pp. 265-270
    • Goodfellow, J.1    Bellamy, M.F.2    Ramsey, M.W.3    Jones, C.J.H.4    Lewis, M.J.5
  • 35
    • 60249089128 scopus 로고    scopus 로고
    • Omega-3 fatty acids plus rosuvastatin improves endothelial function in South Asians with dyslipidemia
    • Mindrescu, C., Gupta, R.P., Hermance, E.V., DeVoe, M.C., Soma, V.R., Coppola, J.T., et al. Omega-3 fatty acids plus rosuvastatin improves endothelial function in South Asians with dyslipidemia. Vasc. Health Risk Manag. 4 (2008), 1439–1447.
    • (2008) Vasc. Health Risk Manag. , vol.4 , pp. 1439-1447
    • Mindrescu, C.1    Gupta, R.P.2    Hermance, E.V.3    DeVoe, M.C.4    Soma, V.R.5    Coppola, J.T.6
  • 36
    • 84983666633 scopus 로고    scopus 로고
    • Effects of 6-month eicosapentaenoic acid treatment on postprandial hyperglycemia, hyperlipidemia, insulin secretion ability, and concomitant endothelial dysfunction among newly-diagnosed impaired glucose metabolism patients with coronary artery disease
    • Sawada, T., Tsubata, H., Hashimoto, N., Takabe, M., Miyata, T., Aoki, K., et al. Effects of 6-month eicosapentaenoic acid treatment on postprandial hyperglycemia, hyperlipidemia, insulin secretion ability, and concomitant endothelial dysfunction among newly-diagnosed impaired glucose metabolism patients with coronary artery disease. A. Cardiovasc. Diabetol., 15, 2016, 121, 10.1186/s12933-016-0437-y.
    • (2016) A. Cardiovasc. Diabetol. , vol.15 , pp. 121
    • Sawada, T.1    Tsubata, H.2    Hashimoto, N.3    Takabe, M.4    Miyata, T.5    Aoki, K.6
  • 37
    • 0037211979 scopus 로고    scopus 로고
    • Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients
    • doi:S0021915002003076
    • Woodman, R.J., Mori, T a, Burke, V., Puddey, I.B., Barden, a, Watts, G.F., et al. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients. Atherosclerosis 166 (2003), 85–93 doi:S0021915002003076.
    • (2003) Atherosclerosis , vol.166 , pp. 85-93
    • Woodman, R.J.1    Mori, T.A.2    Burke, V.3    Puddey, I.B.4    Barden, A.5    Watts, G.F.6
  • 38
    • 73949099366 scopus 로고    scopus 로고
    • Fish-oil supplement has neutral effects on vascular and metabolic function but improves renal function in patients with type 2 diabetes mellitus
    • Wong, C.Y., Yiu, K.H., Li, S.W., Lee, S., Tam, S., Lau, C.P., et al. Fish-oil supplement has neutral effects on vascular and metabolic function but improves renal function in patients with type 2 diabetes mellitus. Diabet. Med. 27 (2010), 54–60, 10.1111/j.1464-5491.2009.02869.x.
    • (2010) Diabet. Med. , vol.27 , pp. 54-60
    • Wong, C.Y.1    Yiu, K.H.2    Li, S.W.3    Lee, S.4    Tam, S.5    Lau, C.P.6
  • 39
    • 77749264445 scopus 로고    scopus 로고
    • Effects of n – 3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus 1 – 3
    • Stirban, A., Nandrean, S., Go, C., Tamler, R., Pop, A., Negrean, M., et al. Effects of n – 3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus 1 – 3. Am. J. Clin. Nutr. 91 (2010), 808–813, 10.3945/ajcn.2009.28374.1.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 808-813
    • Stirban, A.1    Nandrean, S.2    Go, C.3    Tamler, R.4    Pop, A.5    Negrean, M.6
  • 40
    • 84902547022 scopus 로고    scopus 로고
    • A fish-based diet intervention improves endothelial function in postmenopausal women with type 2 diabetes mellitus: a randomized crossover trial
    • Kondo, K., Morino, K., Nishio, Y., Kondo, M., Nakao, K., Nakagawa, F., et al. A fish-based diet intervention improves endothelial function in postmenopausal women with type 2 diabetes mellitus: a randomized crossover trial. Metabolism 63 (2014), 930–940, 10.1016/j.metabol.2014.04.005.
    • (2014) Metabolism , vol.63 , pp. 930-940
    • Kondo, K.1    Morino, K.2    Nishio, Y.3    Kondo, M.4    Nakao, K.5    Nakagawa, F.6
  • 42
    • 84856179128 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review
    • Jacobson, T.A., Glickstein, S.B., Rowe, J.D., Soni, P.N., Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review. J. Clin. Lipidol. 6 (2012), 5–18.
    • (2012) J. Clin. Lipidol. , vol.6 , pp. 5-18
    • Jacobson, T.A.1    Glickstein, S.B.2    Rowe, J.D.3    Soni, P.N.4
  • 43
    • 85033502141 scopus 로고    scopus 로고
    • Review of cardiometabolic effects of prescription omega-3 fatty acids
    • Burke, M.F., Burke, F.M., Soffer, D.E., Review of cardiometabolic effects of prescription omega-3 fatty acids. Curr. Atherosclerosis Rep., 19, 2017, 60.
    • (2017) Curr. Atherosclerosis Rep. , vol.19 , pp. 60
    • Burke, M.F.1    Burke, F.M.2    Soffer, D.E.3
  • 44
    • 84965081917 scopus 로고    scopus 로고
    • Omega-3 fatty acid formulations in cardiovascular disease: dietary supplements are not substitutes for prescription products
    • Fialkow, J., Omega-3 fatty acid formulations in cardiovascular disease: dietary supplements are not substitutes for prescription products. Am. J. Cardiovasc. Drugs 16 (2016), 229–239.
    • (2016) Am. J. Cardiovasc. Drugs , vol.16 , pp. 229-239
    • Fialkow, J.1
  • 45
    • 0034641662 scopus 로고    scopus 로고
    • Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in
    • Mori, T.A., Watts, G.F., Burke, V., Hilme, E., Puddey, I.B., Beilin, L.J., Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in. Circulation 102 (2000), 1264–1269.
    • (2000) Circulation , vol.102 , pp. 1264-1269
    • Mori, T.A.1    Watts, G.F.2    Burke, V.3    Hilme, E.4    Puddey, I.B.5    Beilin, L.J.6
  • 46
    • 85042847025 scopus 로고    scopus 로고
    • Current perspective cardiovascular protective effects of n-3 polyunsaturated fatty acids with special emphasis on docosahexaenoic acid
    • Hirafuji, M., Machida, T., Hamaue, N., Minami, M., Current perspective cardiovascular protective effects of n-3 polyunsaturated fatty acids with special emphasis on docosahexaenoic acid., 316, 2003, 308–316.
    • (2003) , vol.316 , pp. 308-316
    • Hirafuji, M.1    Machida, T.2    Hamaue, N.3    Minami, M.4
  • 47
    • 84929260802 scopus 로고    scopus 로고
    • Is there a relationship between exercise - induced endothelial progenitor cell mobilization and cytokine concentrations in patients with premature coronary heart disease, (n.d.)
    • M. Kaźmierski, M. Tendera, E. Podolecka, M. Włudarczyk, A.L. Bal, W. Wojakowski, Is there a relationship between exercise - induced endothelial progenitor cell mobilization and cytokine concentrations in patients with premature coronary heart disease, (n.d.) 305–307.
    • Kaźmierski, M.1    Tendera, M.2    Podolecka, E.3    Włudarczyk, M.4    Bal, A.L.5    Wojakowski, W.6
  • 48
    • 0030671108 scopus 로고    scopus 로고
    • Dietary supplementation with marine fish oil improves in vitro small artery endothelial function in hypercholesterolemic patients
    • Goode, G., Garcia, S., Heagerty, A., Dietary supplementation with marine fish oil improves in vitro small artery endothelial function in hypercholesterolemic patients. Circulation 96 (1997), 2802–2807.
    • (1997) Circulation , vol.96 , pp. 2802-2807
    • Goode, G.1    Garcia, S.2    Heagerty, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.