Dietary supplementation with marine fish oil improves in vitro small artery endothelial function in hypercholesterolemic patients: A double-blind placebo-controlled study

Circulation

Volumn 96, Issue 9, 1997, Pages 2802-2807

  Goode, Grahame K ^a,b   Garcia, Susana ^a   Heagerty, Anthony M ^a  

^a Department of Medicine ^*  (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Arteries marine fish oil; Endothelium; Hypercholesterolemia

Indexed keywords

FISH OIL;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0030671108     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.9.2802     Document Type: Article

References (32)

1. Zeiher AM, Drexler H, Wollschager H, Just H. Modulation of coronary vasomotor tone in humans: progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation. 1991;83:391-401.
2. Creager MA, Cooke JP, Mendlesohn ME, Gallagher SJ, Coleman SM, Loscalzo J, Dzau VJ. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest. 1990;86:228-234.
3. Goode GK, Miller JP, Heagerty AM. Hyperlipidaemia, hypertension and coronary heart disease. Lancet. 1995;345;362-364.
4. Lehmann ED, Watts GF, Fatemi-Langroudi B, Gosling RG. Aortic compliance in young patients with heterozygous familial hypercholesterolemia. Clin Sci. 1992;83:717-721.
5. Celermayer DS, Sorensen KE, Gooch UM, Spiegelhalter DJ, Miller OI, Sullivan ID, Lloyd JK, Deanfield JE. Noninvasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992;340:1111-1115.
6. Goode GK, Heagerty AM. In vitro responses of human peripheral small arteries in hypercholesterolemia and the effects of therapy. Circulation. 1995;91:2898-2903.
7. Vollset SE, Heuch I, Bielke E. Fish consumption and mortality from coronary heart disease. N Engl J Med. 1985;313:820-821.
8. Curb JD, Reed DM. Fish consumption and mortality from coronary heart disease. N Engl J Med. 1985;313:821-822.
9. Kromhout D, Bosschieter EB, deLezenne Coulander C. The inverse relation between fish consumption and 20 year mortality from coronary heart disease N Engl J Med. 1985;312:1205-1209.
10. Shekelle RB, Missell LV, Paul O, Shyrock AM, Stamler J. Fish consumption and mortality from coronary heart disease. N Engl J Med. 1985;313:820.
11. Ascherio A, Rimm EB, Stampfer MJ, Giovannucci EL, Willett WC. Dietary intake of marine n-3 fatty acids, fish intake and the risk of coronary disease among men. N Engl J Med. 1995;332:977-982.
12. Phillipson BE, Rothrock DW, Connor WE, Harris WS, Illingworth D. Reduction of plasma lipids, lipoproteins and apoproteins by dietary fish oils in patients with hypertriglyceridaemia. N Engl J Med. 1985;312:1210-1216.
13. Morris MC, Sacks F, Rosner B. Does fish oil lower blood pressure? A meta-analysis of controlled trials. Circulation. 1993;88:523-533.
14. Dyerberg J, Bung HO. Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet. 1979;2:433-435.
15. Leaf A, Weber PC. Cardiovascular effects of N-3 fatty acids. N Engl J Med. 1985;312:1205-1209.
16. Aalkjaer C, Pedersen EB, Danielsen H. Morphological and functional characteristics of isolated resistance vessels in advanced uremia. Clin Sci. 1986;71:657-663.
17. Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res. 1977;41:19-26.
18. Taylor AJ, Pandlov HI, Lawson N. Determination of erythrocyte fatty acids by capillary gas liquid chromatography. Am Clin Biochem. 1987;24:293-300.
19. Shimokawa H, Jules Y, Lam T, Chesebro JH, Bowie EJW, Vanhoutte PM. Effects of dietary supplementation with cod-liver oil on endothelium-dependent responses in porcine coronary arteries. Circulation. 1987;76:898-905.
20. Chin JPF, Dart AM. Therapeutic restoration of endothelial function in hypercholesterolaemic subjects: the effect of fish oils. Clin Exp Pharmacol Physiol. 1994;21:749-755.
21. Chin JPF, Gust AP, Nestel PJ, Dart AM. Marine oils dose-dependently inhibit vasoconstriction of forearm resistance arteries in man. Hypertension. 1993;21:22-28.
22. Chin JPF, Kaye DM, Hurlston RM, Angus JA, Jennings GL, Dart AM. Effects of marine fish oil supplementation on reactivity of human buttock subcutaneous arteries and forearm veins in vitro. B J Pharmacol. 1994;112:566-570.
23. Murad F. Cyclic guanosine monophosphate as a mediator of vasodilation. J Clin Invest. 1986;73:1-5.
24. Witzum JL, Steinberg D. Evidence for the presence of oxidatively modified LDL in human atherosclerotic lesions. Circulation. 1989; 80(suppl II):II-160. Abstract.
25. Chowienczyk PJ, Watts GF, Cockcroft JR, Ritter JM. Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia. Lancet. 1992;340:1430-1432.
26. Casino PR, Kilcoyne CM, Quyyumi AA, Hoeg JM, Panza JA. The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients Circulation. 1993;88:2541-2547.
27. Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546-2551.
28. Belcher JD, Balla J, Balla G, Jacobs DR Jr, Gross M, Jacob HS, Vercellotti M. Vitamin E, LDL and endothelium: brief oral vitamin supplementation prevents oxidized LDL-mediated vascular injury in vitro. Arterioscler Thromb. 1993;1779-1789.
29. Golino P, Pisclone F, Willerson JT, Coppelli-Bigazzi M, Focaccio A, Villari B, Indolfi C, Russolillo E, Condorelli M, Chiariello M. Divergent effects of serotonin on coronary artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med. 1991;324:641-648.
30. Anderson P, Arnesen H, Hjermann I. Hyperlipoproteinemia and reduced fibrinolytic activity in healthy coronary high-risk men. Acta Med Scand. 1981;209:199-202.
31. Stiko-rahm A, Wiman B, Hamsten A, Nilsson J. Secretion of plasminogen activator inhibitor-1 from cultured human umbilical vein endothelial cells is induced by very low density lipoprotein. Arteriosclerosis. 1990;10:1067-1073.
32. Anderson TJ, Uehata A, Gerhard MD Meredith IT, Knab S. Delagrange D, Lieberman EH, Ganz P, Creager MA, Yeung AC. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995;26:1235-1241.