Omega-3 polyunsaturated fatty acids increase plasma adiponectin to leptin ratio in stable coronary artery disease

Cardiovascular Drugs and Therapy

Volumn 27, Issue 4, 2013, Pages 289-295

  Mostowik, Magdalena ^a,b   Gajos, Grzegorz ^a,b   Zalewski, Jaroslaw ^a,b   Nessler, Jadwiga ^a,b   Undas, Anetta ^a,b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b Krakowski Szpital Specjalistyczny Im Jana Pawła II   (Poland)

Author keywords

Adiponectin; Leptin; Omega 3 polyunsaturated fatty acids; Percutaneous coronary intervention; Resistin; Stable coronary artery disease

Indexed keywords

ACETYLSALICYLIC ACID; ADIPOCYTOKINE; ADIPONECTIN; CHOLESTEROL; CLOPIDOGREL; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LEPTIN; OMEGA 3 FATTY ACID; PLACEBO; RESISTIN;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEMALE; HEART PROTECTION; HIGH RISK PATIENT; HUMAN; HYPERLIPIDEMIA; LOADING DRUG DOSE; MALE; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SMOKING; STATISTICAL MODEL; THROMBOCYTE COUNT; WAIST CIRCUMFERENCE;

ADIPONECTIN; AGED; CARDIOTONIC AGENTS; CORONARY ARTERY DISEASE; DOUBLE-BLIND METHOD; FATTY ACIDS, OMEGA-3; FEMALE; HUMANS; LEPTIN; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; RESISTIN;

EID: 84880252433     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-013-6457-x     Document Type: Article

References (29)

1. Kar S, Webel R. Fish oil supplementation & coronary artery disease: does it help? Mo Med. 2012;109:142-5.
2. Mizia-Stec K, Haberka M, Mizia M, et al. N-3 Polyunsaturated fatty acid therapy improves endothelial function and affects adiponectin and resistin balance in the first month after myocardial infarction. Arch Med Sci. 2011;7:788-95.
3. Gajos G, Rostoff P, Undas A, et al. Effect of polyunsaturated omega-3 fatty acids on responsiveness to dual antiplatelet therapy in patients undergoing percutaneus coronary intervention: the OMEGA-PCI study. J Am Coll Cardiol. 2010;55:1671-8.
4. Gajos G, Zalewski J, Rostoff P, et al. Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturated omega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneus coronary intervention (OMEGA-PCI clot.). Arterioscler Thromb Vasc Biol. 2011;31:1696-702.
5. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The fifth joint task force of the european society of cardiology and other societies on cardiovascular disease prevention in clinical practice. Eur Heart J. 2012;33:1635-701.
6. Kromhout D, Giltay EJ, Geleijnse JM. Alpha Omega Trial Group. n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med. 2010;363:2015-26.
7. Chaldakov GN, Stankulov IS, Hristova M, Ghenev PI. Adipobiology of disease: adipokines and adipokine-targeted pharmacology. Curr Pharm Des. 2003;9:1023-31.
8. West of Scotland Coronary Prevention Study: identification of high-risk groups and comparison with other cardiovascular intervention trials. Lancet. 1996; 348(9038):1339-42.
9. Shioji K, Moriwaki S, Takeuchi Y, Uegaito T, Mutsuo S, Matsuda M. Relationship of serum adiponectin level to adverse cardiovascular events in patients who undergo percutaneous coronary intervention. Circ J. 2007;71:675-80.
10. Nogueiras R, Novelle MG, Vazquez MJ, Lopez M, Dieguez C. Resistin: regulation of food intake, glucose homeostasis and lipid metabolism. Endocr Dev. 2010;17:175-84.
11. Masquio DC, de Piano A, Sanches PL. The effect of weight loss magnitude on pro/anti-inflammatory adipokines and carotid intima-media thickness in obese adolescents engaged in interdisciplinary weight-loss therapy. Clin Endocrinol (Oxf). 2012 [Epub ahead of print].
12. Sassen LM, Lamers JM, Sluiter W, et al. Development and regression of atherosclerosis in pigs. Effects of n-3 fatty acids, their incorporation into plasma and aortic plaque lipids, and granulocyte function. Arterioscler Thromb. 1993;13:651-60.
13. Guallar E, Aro A, Jiménez FJ, et al. Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: the EURAMIC study. Arterioscler Thromb Vasc Biol. 1999;19:1111-8.
14. Moreno-Aliaga MJ, Lorente-Cebrián S, Martínez JA. Regulation of adipokine secretion by n-3 fatty acids. Proc Nutr Soc. 2010;69:324-32.
15. Wanders D, Plaisance EP, Judd RL. Pharmacological effects of lipid-lowering drugs on circulating adipokines. World J Diabetes. 2010;1:116-28.
16. Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-5.
17. Sakamoto K, Sakamoto T, Ogawa H, Kurnamoto Joint Research on Hypercholesterolemia Investigators. The effect of 6 months of treatment with pravastatin on serum adiponection concentrations in Japanese patients with coronary artery disease and hypercholesterolemia: a pilot study. Clin Ther. 2006;28:1012-21.
18. Kolasa-Trela R, Miszalski-Jamka T, Grudzień G, Wypasek E, Kostkiewicz M. Adiponectin, leptin, and resistin in patients with aortic stenosis without concomitant atherosclerotic vascular disease. Pol Arch Med Wewn. 2011;121:352-9.
19. Rossi AS, Lombardo YB, Lacorte JM, et al. Dietary fish oil positively regulates plasma leptin and adiponectin levels in sucrose-fed, insulin-resistant rats. Am J Physiol Regul Integr Comp Physiol. 2005;289:486-94.
20. Itoh M, Suganami T, Satoh N, et al. Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol. 2007;27:1918-25.
21. Kratz M, Swarbrick MM, Callahan HS, Matthys CC, Havel PJ, Weigle DS. Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecular-weight adiponectin concentrations in overweight to moderately obese men and women. Am J Clin Nutr. 2008;87:347-53.
22. Puglisi MJ, Hasty AH, Saraswathi V. The role of adipose tissue in mediating the beneficial effects of dietary fish oil. J Nutr Biochem. 2011;22:101-8.
23. Sneddon AA, Tsofliou F, Fyfe CL, et al. Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin. Obesity. 2008;16:1019-24.
24. Haugen F, Zahid N, Dalen KT, Hollung K, Nebb HI, Drevon CA. Resistin expression in 3T3-L1 adipocytes is reduced by arachidonic acid. J Lipid Res. 2005;46:143-53.
25. Neschen S, Morino K, Rossbacher JC. Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice. Diabetes. 2006;55:924-8.
26. Kallen CB, Lazar MA. Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci USA. 1996;93:5793-6.
27. Zaletel J, Barlovic DP, Prezelj J. Adiponectin-leptin ratio: a useful estimate of insulin resistance in patients with Type 2 diabetes. J Endocrinol Invest. 2010;33:514-8.
28. Kotani K, Sakane N, Saiga K, Kurozawa Y. Leptin:adiponectin ratio as an atherosclerotic index in patients with type 2 diabetes: relationship of the index to carotid intima-media thickness. Diabetologia. 2005;48:2684-6.
29. Rizos EC, Ntzani EE, Bika E, Kostapanos MS, Elisaf MS. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA. 2012;308:1024-33.