메뉴 건너뛰기




Volumn 13, Issue 3, 2013, Pages 403-410

Hyperglycemia and vascular metabolic memory: Truth or fiction?

Author keywords

ACCORD; ADVANCE; Advanced glycation; Epigenetic mechanisms; Glucose control; Hyperglycemia; Intervention trials; Metabolic legacy; ORIGIN; Oxidative stress; Type 1 diabetes; Type 2 diabetes; UKPDS; VADT; Vascular metabolic memory

Indexed keywords

ADVANCED GLYCATION END PRODUCT; GLUCOSE; HEMOGLOBIN A1C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INSULIN GLARGINE; METFORMIN; PROTEIN KINASE C; PROTEIN KINASE C BETA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SULFONYLUREA; SYNAPTOTAGMIN I;

EID: 84877766193     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-013-0371-2     Document Type: Article
Times cited : (47)

References (51)
  • 1
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world - A growing challenge
    • DOI 10.1056/NEJMp068177
    • Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world: a growing challenge. N Engl J Med. 2007;356:213-5. (Pubitemid 46143224)
    • (2007) New England Journal of Medicine , vol.356 , Issue.3 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 2
    • 79959936188 scopus 로고    scopus 로고
    • Global burden of metabolic risk factors of chronic diseases collaborating Group (Blood Glucose). National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
    • 21705069 10.1016/S0140-6736(11)60679-X 1:CAS:528:DC%2BC3MXotlyltbo%3D
    • Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, et al. Global burden of metabolic risk factors of chronic diseases collaborating Group (Blood Glucose). National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants. Lancet. 2011;378:31-40.
    • (2011) Lancet , vol.378 , pp. 31-40
    • Danaei, G.1    Finucane, M.M.2    Lu, Y.3    Singh, G.M.4    Cowan, M.J.5    Paciorek, C.J.6
  • 3
    • 55849120862 scopus 로고    scopus 로고
    • Epidemiology of diabetes and diabetes-related complications
    • 18801858 10.2522/ptj.20080020
    • Deshpande AD, Harris-Hayes M, Schootman M. Epidemiology of diabetes and diabetes-related complications. Phys Ther. 2008;88:1254-64.
    • (2008) Phys Ther , vol.88 , pp. 1254-1264
    • Deshpande, A.D.1    Harris-Hayes, M.2    Schootman, M.3
  • 4
    • 84863400114 scopus 로고    scopus 로고
    • Prevalence and risk factors for diabetic microvascular complications in newly diagnosed type II diabetes mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, report 27)
    • 22446033 10.1016/j.jdiacomp.2012.02.001
    • Raman R, Gupta A, Krishna S, Kulothungan V, Sharma T. Prevalence and risk factors for diabetic microvascular complications in newly diagnosed type II diabetes mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, report 27). J Diabetes Complicat. 2012;26:123-8.
    • (2012) J Diabetes Complicat , vol.26 , pp. 123-128
    • Raman, R.1    Gupta, A.2    Krishna, S.3    Kulothungan, V.4    Sharma, T.5
  • 6
    • 0022616928 scopus 로고
    • Relationship of clinical diabetes and asymptomatic hyperglycemia to risk of coronary heart disease mortality in men and women
    • Pan WH, Cedres LB, Liu K, Dyer A, Schoenberger JA, Shekelle RB, et al. Relationship of clinical diabetes and asymptomatic hyperglycemia to risk of coronary heart disease mortality in men and women. Am J Epidemiol. 1986;123:504-16. (Pubitemid 16101155)
    • (1986) American Journal of Epidemiology , vol.123 , Issue.3 , pp. 504-516
    • Pan, W.-H.1    Cedres, L.B.2    Liu, K.3
  • 7
    • 79952260576 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting glucose, and risk of cause-specific death
    • The Emerging Risk Factors Collaboration et al. 21366474 10.1056/NEJMoa1008862 1:CAS:528:DC%2BC3MXivFSjtrk%3D
    • Seshasai SR, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, The Emerging Risk Factors Collaboration, et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med. 2011;364:829-41.
    • (2011) N Engl J Med , vol.364 , pp. 829-841
    • Seshasai, S.R.1    Kaptoge, S.2    Thompson, A.3    Di Angelantonio, E.4    Gao, P.5
  • 9
    • 38949161942 scopus 로고    scopus 로고
    • Paget's disease of the mandible
    • DOI 10.1056/NEJMicm066227
    • Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560-72. (Pubitemid 351214289)
    • (2008) New England Journal of Medicine , vol.358 , Issue.6 , pp. 625
    • Patel, M.B.1    Bhalla, A.2
  • 10
    • 58149389215 scopus 로고    scopus 로고
    • Intensive glucose control and complications in American veterans with type 2 diabetes
    • 19092145 10.1056/NEJMoa0808431 1:CAS:528:DC%2BD1MXnsFWkug%3D%3D
    • Duckworth W, Abraira C, Moritz T, et al. Intensive glucose control and complications in American veterans with type 2 diabetes. N Engl J Med. 2009;360:129-39.
    • (2009) N Engl J Med , vol.360 , pp. 129-139
    • Duckworth, W.1    Abraira, C.2    Moritz, T.3
  • 11
    • 84862840492 scopus 로고    scopus 로고
    • Intensive glucose-lowering therapy in people with type 2 diabetes: What do we learn from a new meta-analysis of randomized controlled trials?
    • 22127338 10.1136/ebmed-2011-100230
    • Turnbull F, Zoungas S. Intensive glucose-lowering therapy in people with type 2 diabetes: what do we learn from a new meta-analysis of randomized controlled trials? Evid Based Med. 2012;17:98-9.
    • (2012) Evid Based Med , vol.17 , pp. 98-99
    • Turnbull, F.1    Zoungas, S.2
  • 12
    • 67349251550 scopus 로고    scopus 로고
    • Mega-trials in type 2 diabetes. from excitement to frustration?
    • 19373446 10.1007/s00125-009-1352-5 1:CAS:528:DC%2BD1MXms1yhsL4%3D
    • Del Prato S. Mega-trials in type 2 diabetes. From excitement to frustration? Diabetologia. 2009;52:1219-26.
    • (2009) Diabetologia , vol.52 , pp. 1219-1226
    • Del Prato, S.1
  • 13
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • DOI 10.1016/S0140-6736(98)07019-6
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837-53. (Pubitemid 28416718)
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 837-853
    • Turner, R.1
  • 14
    • 53749096863 scopus 로고    scopus 로고
    • 10-year follow-up of intensive glucose control in type 2 diabetes
    • 18784090 10.1056/NEJMoa0806470 1:CAS:528:DC%2BD1cXht1Wgt7nK
    • Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med. 2008;359:1577-89.
    • (2008) N Engl J Med , vol.359 , pp. 1577-1589
    • Holman, R.R.1    Paul, S.K.2    Bethel, M.A.3    Matthews, D.R.4    Neil, H.A.5
  • 16
    • 58149252632 scopus 로고    scopus 로고
    • Diabetes control and complications trial/epidemiology of diabetes interventions and complications research group prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus. Ten years after the diabetes control and complications trial
    • Diabetes control and complications trial/epidemiology of diabetes interventions and complications research group prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus. Ten years after the diabetes control and complications trial. Arch Ophthalmol. 2008; 126:1707-15.
    • (2008) Arch Ophthalmol , vol.126 , pp. 1707-1715
  • 17
    • 79951715424 scopus 로고    scopus 로고
    • Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: Results from the DCCT/EDIC study
    • 20833868 10.2337/dc10-0616
    • Martin CL, Waberski BH, Pop-Busui R, Cleary PA, Catton S, Albers JW, et al. Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the DCCT/EDIC study. Diabetes Care. 2010;33:2635-41.
    • (2010) Diabetes Care , vol.33 , pp. 2635-2641
    • Martin, C.L.1    Waberski, B.H.2    Pop-Busui, R.3    Cleary, P.A.4    Catton, S.5    Albers, J.W.6
  • 18
    • 84872675171 scopus 로고    scopus 로고
    • Association between cardiovascular autonomic neuropathy and left ventricular dysfunction in the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study
    • Pop-Busui R, Cleary PA, Braffett BH, Martin CL, Herman WH, Low PA, et al. Association between cardiovascular autonomic neuropathy and left ventricular dysfunction in the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study. J Am Coll Cardiol. 2013;61:447-54.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 447-454
    • Pop-Busui, R.1    Cleary, P.A.2    Braffett, B.H.3    Martin, C.L.4    Herman, W.H.5    Low, P.A.6
  • 19
    • 84855245399 scopus 로고    scopus 로고
    • Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes
    • 22077236 10.1056/NEJMoa1111732 This is the most recent paper from the DCCT/EDIC investigators confirming persistent beneficial effects in type 1 diabetic patients with initial intensive vs conventional treatment
    • de Boer IH, Sun W, Cleary PA, Lachin JM, Molitch ME, Steffes MW, et al. Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. N Engl J Med. 2011;365:2366-76. This is the most recent paper from the DCCT/EDIC investigators confirming persistent beneficial effects in type 1 diabetic patients with initial intensive vs conventional treatment.
    • (2011) N Engl J Med , vol.365 , pp. 2366-2376
    • De Boer, I.H.1    Sun, W.2    Cleary, P.A.3    Lachin, J.M.4    Molitch, M.E.5    Steffes, M.W.6
  • 21
    • 77952012602 scopus 로고    scopus 로고
    • The shape of the metabolic memory of HbA1c: Re-analyzing the DCCT with respect to time-dependent effects
    • 20237754 10.1007/s00125-010-1706-z 1:STN:280:DC%2BC3c3pt1ertw%3D%3D
    • Lind M, Odén A, Fahlén M, Eliasson B. The shape of the metabolic memory of HbA1c: re-analyzing the DCCT with respect to time-dependent effects. Diabetologia. 2010;53:1093-8.
    • (2010) Diabetologia , vol.53 , pp. 1093-1098
    • Lind, M.1    Odén, A.2    Fahlén, M.3    Eliasson, B.4
  • 24
    • 79952273819 scopus 로고    scopus 로고
    • Long-term effects of intensive glucose lowering on cardiovascular outcomes
    • 21366473 10.1056/NEJMoa1006524 1:CAS:528:DC%2BC3MXivV2qurw%3D
    • Gerstein HC, Miller ME, Genuth S, Ismail-Beigi F, Buse JB, Goff Jr DC, et al. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med. 2011;364:818-28.
    • (2011) N Engl J Med , vol.364 , pp. 818-828
    • Gerstein, H.C.1    Miller, M.E.2    Genuth, S.3    Ismail-Beigi, F.4    Buse, J.B.5    Goff Jr., D.C.6
  • 25
    • 71049118192 scopus 로고    scopus 로고
    • Intensive glucose-lowering therapy reduces cardiovascular disease events in Veterans Affairs Diabetes Trial participants with lower calcified coronary atherosclerosis
    • 19651816 10.2337/db09-0618 1:CAS:528:DC%2BD1MXhsVCht7%2FP
    • Reaven PD, Moritz TE, Schwenke DC, Anderson RJ, Criqui M, Detrano R, et al. Intensive glucose-lowering therapy reduces cardiovascular disease events in Veterans Affairs Diabetes Trial participants with lower calcified coronary atherosclerosis. Diabetes. 2009;58:2642-8.
    • (2009) Diabetes , vol.58 , pp. 2642-2648
    • Reaven, P.D.1    Moritz, T.E.2    Schwenke, D.C.3    Anderson, R.J.4    Criqui, M.5    Detrano, R.6
  • 26
    • 79960245269 scopus 로고    scopus 로고
    • Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION Europe): A cluster-randomized trial
    • 21705063 10.1016/S0140-6736(11)60698-3
    • Griffin SJ, Borch-Johnsen K, Davies MJ, Khunti K, Rutten GE, Sandbæk A, et al. Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION Europe): a cluster-randomized trial. Lancet. 2011;378:156-67.
    • (2011) Lancet , vol.378 , pp. 156-167
    • Griffin, S.J.1    Borch-Johnsen, K.2    Davies, M.J.3    Khunti, K.4    Rutten, G.E.5    Sandbæk, A.6
  • 27
    • 84875433076 scopus 로고    scopus 로고
    • Primary prevention of macroangiopathy in patients with short-duration type 2 diabetes by intensified multifactorial intervention: Seven-year follow-up of diabetes complications in Chinese
    • doi: 10.2337/dc12-0227
    • Yang Y, Yao JJ, Du JL, Bai R, Sun LP, Sun GH, et al. Primary prevention of macroangiopathy in patients with short-duration type 2 diabetes by intensified multifactorial intervention: seven-year follow-up of diabetes complications in Chinese. Diabetes Care. 2012. doi: 10.2337/dc12-0227
    • (2012) Diabetes Care
    • Yang, Y.1    Yao, J.J.2    Du, J.L.3    Bai, R.4    Sun, L.P.5    Sun, G.H.6
  • 28
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • 22686416 10.1056/NEJMoa1203858 1:CAS:528:DC%2BC38XhtFegsrvN
    • Gerstein HC, Bosch J, Dagenais GR, Díaz R, Jung H, Maggioni AP, et al. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med. 2012;367:319-28.
    • (2012) N Engl J Med , vol.367 , pp. 319-328
    • Gerstein, H.C.1    Bosch, J.2    Dagenais, G.R.3    Díaz, R.4    Jung, H.5    Maggioni, A.P.6
  • 29
    • 84877790387 scopus 로고    scopus 로고
    • Accessed on January 3, 2013
    • The ORIGINALE Study. http://origintrial.org/Assets/PDF/ ORIGINALE%20Protocol.pdf. Accessed on January 3, 2013.
    • The ORIGINALE Study
  • 30
    • 0023641117 scopus 로고
    • Progression of incipient diabetic retinopathy during good glycemic control
    • Engerman RL, Kern TS. Progression of incipient diabetic retinopathy during good glycemic control. Diabetes. 1987;36:808-12. (Pubitemid 17145301)
    • (1987) Diabetes , vol.36 , Issue.7 , pp. 808-812
    • Engerman, R.L.1    Kern, T.S.2
  • 32
    • 0037342855 scopus 로고    scopus 로고
    • Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats
    • DOI 10.2337/diabetes.52.3.818
    • Kowluru RA. Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats. Diabetes. 2003;52:818-23. (Pubitemid 36323591)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 818-823
    • Kowluru, R.A.1
  • 33
    • 12944302088 scopus 로고    scopus 로고
    • Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kB) in the retina
    • DOI 10.1007/s00592-004-0165-8
    • Kowluru RA, Chakrabarti S, Chen S. Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina. Acta Diabetol. 2004;41:194-9. (Pubitemid 40174996)
    • (2004) Acta Diabetologica , vol.41 , Issue.4 , pp. 194-199
    • Kowluru, R.A.1    Chakrabarti, S.2    Chen, S.3
  • 34
    • 34547858127 scopus 로고    scopus 로고
    • Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries
    • 17641740
    • Kowluru RA, Kanwar M, Kennedy A. Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries. Exp Diabetes Res. 2007;2007:21976.
    • (2007) Exp Diabetes Res , vol.2007 , pp. 21976
    • Kowluru, R.A.1    Kanwar, M.2    Kennedy, A.3
  • 35
    • 73149121384 scopus 로고    scopus 로고
    • Metabolic memory in diabetes - From in vitro oddity to in vivo problem: Role of apoptosis
    • 19463916 10.1016/j.brainresbull.2009.05.006 1:CAS:528: DC%2BC3cXkt1Crtg%3D%3D
    • Kowluru RA, Chan PS. Metabolic memory in diabetes - from in vitro oddity to in vivo problem: role of apoptosis. Brain Res Bull. 2010;81:297-302.
    • (2010) Brain Res Bull , vol.81 , pp. 297-302
    • Kowluru, R.A.1    Chan, P.S.2
  • 36
    • 4444335298 scopus 로고    scopus 로고
    • Reversal of hyperglycemia and diabetic nephropathy: Effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats
    • DOI 10.1016/j.jdiacomp.2004.03.002, PII S1056872704000236
    • Kowluru RA, Abbas SN, Odenbach S. Reversal of hyperglycemia and diabetic nephropathy: effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats. J Diabetes Complicat. 2004;18:282-8. (Pubitemid 39165435)
    • (2004) Journal of Diabetes and its Complications , vol.18 , Issue.5 , pp. 282-288
    • Kowluru, R.A.1    Abbas, S.N.2    Odenbach, S.3
  • 38
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • Brownlee M. The pathobiology of diabetes complications: a unifying mechanism. Diabetes. 2005;54:1615-25. (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 39
    • 0037482960 scopus 로고    scopus 로고
    • The role of advanced glycation in the pathogenesis of diabetic retinopathy
    • DOI 10.1016/S0014-4800(03)00035-2
    • Stitt AW. The role of advanced glycation in the pathogenesis of diabetic retinopathy. Exp Mol Pathol. 2003;1:95-108. (Pubitemid 36798117)
    • (2003) Experimental and Molecular Pathology , vol.75 , Issue.1 , pp. 95-108
    • Stitt, A.W.1
  • 40
    • 78049444370 scopus 로고    scopus 로고
    • Glycemic memory associated epigenetic changes
    • 20599797 10.1016/j.bcp.2010.06.005 1:CAS:528:DC%2BC3cXhtlKrsrfE
    • Siebel AL, Fernandez AZ, El-Osta A. Glycemic memory associated epigenetic changes. Biochem Pharmacol. 2010;80:1853-9.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1853-1859
    • Siebel, A.L.1    Fernandez, A.Z.2    El-Osta, A.3
  • 41
    • 78650694320 scopus 로고    scopus 로고
    • Epigenetics: Mechanisms and implications for diabetic complications
    • 21148447 10.1161/CIRCRESAHA.110.223552 1:CAS:528:DC%2BC3cXhsFChsb7J This study provides a thorough description of the current understanding the molecular changes to chromatin structure and the functional relationship with altered signaling pathways that represents the basis of metabolic memory
    • Cooper ME, El-Osta A. Epigenetics: mechanisms and implications for diabetic complications. Circ Res. 2010;107:1403-13. This study provides a thorough description of the current understanding the molecular changes to chromatin structure and the functional relationship with altered signaling pathways that represents the basis of metabolic memory.
    • (2010) Circ Res , vol.107 , pp. 1403-1413
    • Cooper, M.E.1    El-Osta, A.2
  • 42
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • 18809715 10.1084/jem.20081188 1:CAS:528:DC%2BD1cXht1SrtLnN
    • El-Osta A, Brasacchio D, Yao D, Pocai A, Jones PL, Roeder RG, et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med. 2008;205:2409-17.
    • (2008) J Exp Med , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6
  • 43
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • DOI 10.1038/414813a
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001;414:813-20. (Pubitemid 34000785)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 45
    • 0032997958 scopus 로고    scopus 로고
    • Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: Relevance of glycated collagen products versus HbA(1c) as markers of diabetic complications
    • Monnier VM, Bautista O, Kenny D, Sell DR, Fogarty J, Dahms W, et al. Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive vs conventional therapy of type 1 diabetes: relevance of glycated collagen products vs HbA1c as markers of diabetic complications. Diabetes. 1999;48:870-80. (Pubitemid 29153089)
    • (1999) Diabetes , vol.48 , Issue.4 , pp. 870-880
    • Monnier, V.M.1    Bautista, O.2    Kenny, D.3    Sell, D.R.4    Fogarty, J.5    Dahms, W.6    Cleary, P.A.7    Lachin, J.8    Genuth, S.9
  • 46
    • 33644698951 scopus 로고    scopus 로고
    • Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes
    • DOI 10.2337/diabetes.54.11.3103
    • Genuth S, Sun W, Cleary P, Sell DR, Dahms W, Malone J, et al. Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications participants with type 1 diabetes. Diabetes. 2005;54:3103-11. (Pubitemid 43334362)
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3103-3111
    • Genuth, S.1    Sun, W.2    Cleary, P.3    Sell, D.R.4    Dahms, W.5    Malone, J.6    Sivitz, W.7    Monnier, V.M.8
  • 47
    • 77951843664 scopus 로고    scopus 로고
    • Effect of prior intensive therapy in type 1 diabetes on 10-year progression of retinopathy in the DCCT/EDIC: Comparison of adults and adolescents
    • 20150283 10.2337/db09-1216 1:CAS:528:DC%2BC3cXmtFegtro%3D
    • White NH, Sun W, Cleary PA, Tamborlane WV, Danis RP, Hainsworth DP, et al. Effect of prior intensive therapy in type 1 diabetes on 10-year progression of retinopathy in the DCCT/EDIC: comparison of adults and adolescents. Diabetes. 2010;59:1244-53.
    • (2010) Diabetes , vol.59 , pp. 1244-1253
    • White, N.H.1    Sun, W.2    Cleary, P.A.3    Tamborlane, W.V.4    Danis, R.P.5    Hainsworth, D.P.6
  • 48
    • 77954966171 scopus 로고    scopus 로고
    • Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) study
    • 20150297 10.2337/dc09-1941 1:CAS:528:DC%2BC3cXnsFylsbk%3D
    • Albers JW, Herman WH, Pop-Busui R, Feldman EL, Martin CL, Cleary PA, et al. Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) study. Diabetes Care. 2010;33:1090-6.
    • (2010) Diabetes Care , vol.33 , pp. 1090-1096
    • Albers, J.W.1    Herman, W.H.2    Pop-Busui, R.3    Feldman, E.L.4    Martin, C.L.5    Cleary, P.A.6
  • 49
    • 79551593128 scopus 로고    scopus 로고
    • Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study
    • 21270271 10.2337/db10-0296 1:CAS:528:DC%2BC3MXisVOmu7Y%3D
    • Polak JF, Backlund JY, Cleary PA, Harrington AP, O'Leary DH, Lachin JM, et al. Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. Diabetes. 2011;60:607-13.
    • (2011) Diabetes , vol.60 , pp. 607-613
    • Polak, J.F.1    Backlund, J.Y.2    Cleary, P.A.3    Harrington, A.P.4    O'Leary, D.H.5    Lachin, J.M.6
  • 51
    • 57049150338 scopus 로고    scopus 로고
    • Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes
    • 19033589 10.1001/jama.2008.649 1:CAS:528:DC%2BD1cXhsVCgtbvM
    • Doria A, Wojcik J, Xu R, Gervino EV, Hauser TH, Johnstone MT, et al. Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. JAMA. 2008;300:2389-97.
    • (2008) JAMA , vol.300 , pp. 2389-2397
    • Doria, A.1    Wojcik, J.2    Xu, R.3    Gervino, E.V.4    Hauser, T.H.5    Johnstone, M.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.