Cardiovascular and endothelial effects of fish oil supplementation in healthy volunteers

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 12, Issue 3, 2007, Pages 213-219

  Prabodh Shah, Atman ^a   Ichiuji, Anne Marie ^d   Han, Janet K ^c   Traina, Mahmoud ^b   El Bialy, Adel ^b   Kamal Meymandi, Sheba ^b   Yvonne Wachsner, Robin ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b OLIVE VIEW UCLA MEDICAL CENTER   (United States)

^c VA Greater Los Angeles Healthcare System   (United States)

^d KAISER PERMANENTE MEDICAL CENTER   (United States)

Author keywords

Endothelium; Fish oil; Hemodynamics

Indexed keywords

CORN OIL; FISH OIL; PLACEBO;

ADULT; ARTERY BLOOD FLOW; ARTICLE; BLOOD PRESSURE; BRACHIAL ARTERY; CARDIOVASCULAR EFFECT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG CAPSULE; ENDOTHELIUM; FEMALE; HEART RATE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; ULTRASOUND; VASODILATATION; VOLUNTEER;

ADULT; BLOOD PRESSURE; BRACHIAL ARTERY; DIETARY SUPPLEMENTS; DOCOSAHEXAENOIC ACIDS; DRUG COMBINATIONS; EICOSAPENTAENOIC ACID; ENDOTHELIUM, VASCULAR; FEMALE; FISH OILS; HEART RATE; HUMANS; MALE; NITROGLYCERIN; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; ULTRASONOGRAPHY; VASODILATION; VITAMIN E;

EID: 34548164814     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/1074248407304749     Document Type: Article

References (42)

1. Smith SC, Blair SN, Bonow RO, et al. AHA/ACC scientific statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2006 update. Circulation. 2006 ; 113: 2263-2272.
2. Daviglus ML, Stamler J., Orencia AJ, et al. Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med. 1997 ; 336: 1046-1053.
3. Albert CM, Hennekens CH, O'Donnell CJ, et al. Fish consumption and the risk of sudden death. JAMA. 1998 ; 279: 23-28.
4. Albert CM, Campos H., Stampfer MJ, et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med. 2002 ; 346: 1113-1118.
5. Burr ML, Fehily AM, Gilbert JF, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial infarction. Lancet. 1989 ; 2: 757-761.
6. Marchioli R., Barzi F., Bomba E., et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002 ; 105: 1897-1903.
7. Anderson TJ, Uehata A., Gerhard MD, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995 ; 26: 1235-1241.
8. Lieberman EH, Uehata A. Flow mediated vasodilation is impaired in the brachial artery of patients with coronary artery disease or with diabetes mellitus. Clin Res. 1993 ; 41: 217A.
9. Celermajer DS, Sorensen KE, Bull C., Robinson J., Deanfield JE Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992 ; 340: 1111-1115.
10. Neunteufl T., Heher S., Katzenschlager R., Abela C., Niderle B., Stefenelli T. Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain. Am J Cardiol. 2000 ; 86: 207-210.
11. Khan F., Elherik K., Bolton-Smith C., et al. The effects of dietary fatty acid supplementation on endothelial function and vascular tone in healthy subjects. Cardiovasc Res. 2003 ; 59: 955-962.
12. Reneman RS, Van Merode T, Hick P., Hoeks AP Agerelated changes in carotid wall properties in man. Ultrasound Med Biol. 1986 ; 12: 465-471.
13. Krauss RM, Eckel RH, Howard B., et al. AHA dietary guidelines: revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation. 2000 ; 102: 2284-2299.
14. Wardlaw GM Perspectives in Nutrition. 4 th ed. Boston: McGraw-Hill; 1999.
15. Eschen O., Christensen JH, De Caterina R, Schmidt EB Soluble adhesion molecules in healthy subjects: a dose-response study using n-3 fatty acids. Nutr Metab Cardiovasc Dis. 2004 ; 14: 180-185.
16. Cherry PD, Furchgott RF The role of endothelial cell in the relaxation of isolated arteries by bradykinin. Proc Natl Acad Sci U S A. 1983 ; 79: 2106-2110.
17. Rubanyi GM The role of endothelium in cardiovascular homeostasis and disease. J Cardiovasc Pharmacol. 1992 ; 22 (suppl 4). S1 - S14.
18. Vogel RA Coronary risk factors, endothelial function, and atherosclerosis, a review. Clin Cardiol. 1997 ; 84: 12721277.
19. Anderson TJ, Meredith IT, Yeung AC, Frei B., Selwyn AP, Ganz P. The effects of cholesterol lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N Engl J Med. 1995 ; 332: 488-493.
20. Woods RK, Thien FC, Abramson MJ Dietary marine fatty acids for asthma. Cochrane Database Syst Rev. 2000 ;(4). CD001283.
21. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet. 1999 ; 354: 447-455.
22. Singh RB, Niaz MA, Sharma JP, Kumar R., Rastogi V., Moshiri M. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival-4. Cardiovasc Drugs Ther. 1997 ; 11: 485-491.
23. Bairati I., Roy L., Meyer F. Double-blind, randomized, controlled trial of fish oil supplements in prevention of recurrence of stenosis after coronary angioplasty. Circulation. 1992 ; 85: 950-956.
24. Farmer A., Montori V., Dinneen S., Clar C. Fish oil in people with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2000 ; 2: CD001283.
25. Goodfellow J., Bellamy MF, Ramsey MW, Jones CJ, Lewis MJ Dietary supplementation with marine ω-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol. 2000 ; 35: 265-270.
26. Goode GK, Garcia S., Heagerty AM Dietary supplementation with marine fish oil improves in vitro small artery endothelial function in hypercholesterolemic patients: a double blind placebo controlled study. Circulation. 1997 ; 96: 2802-2807.
27. Kang JX, Leaf A. Antiarrhythmic effects of polyunsaturated fatty acids: recent studies. Circulation. 1996 ; 94: 1774-1780.
28. Black KL, Culp B., Madison D., Randall OS, Lands WE The protective effects of dietary fish oil on focal cerebral infarction. Prostaglandins Med. 1979 ; 3: 257-268.
29. Okuda Y., Kawashima K., Sawada T., et al. Eicosapentaenoic acid enhances nitric oxide production by cultured human endothelial cells. Biochem Biophys Res Commun. 1997 ; 232: 487-491.
30. Uauy R., Mena P., Valenzuela A. Essential fatty acids as determinants of lipid requirements in infants, children and adults. Eur J Clin Nutr. 1999 ; 53 (suppl 1). S66 - S77.
31. Bayon Y., Croset M., Daveloose D., et al. Effect of specific phospholipids molecular species incorportated in human platelet membranes on thromboxane A2/prostaglandin H2 receptors. J Lipid Res. 1995 ; 36: 47-56.
32. Billman GE, Kang JX, Leaf A. Prevention of ischemiainduced cardiac sudden death by n-3 polyunsaturated fatty acids in dogs. Lipids. 1997 ; 32: 1161-1168.
33. Dallongeville J., Yarnell J., Ducimetiere P., et al. Fish consumption is associated with lower heart rates. Circulation. 2003 ; 108: 820-825.
34. Albert CM, Hennekens CH, O'Donnell CJ, et al. Fish consumption and risk of sudden cardiac death. JAMA. 1998 ; 279: 23-28.
35. Mori TA, Bao DQ, Burke V., et al. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension. 1999 ; 34: 253-260.
36. Haalaq H., Smith TW, Leaf A. Modulation of dihydropyridinesensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci U S A. 1992 ; 89: 1760-1764.
37. Harris WS, Gonzales M., Laney N., et al. Effects of ω-3 fatty acids on heart rate in cardiac transplant recipients. Am J Cardiol. 2006 ; 98: 1393-1395.
38. Dyer AR, Persky V., Stamler J., et al. Heart rate as a prognostic factor for coronary heart disease and mortality. Am J Epidemiol. 1980 ; 112: 736-749.
39. Dallongeville J., Yarnell J., Ducimetiere P., et al. Fish consumption is associated with lower heart rates. Circulation. 2003 ; 108: 820-825.
40. Grimsgaard S., Bonaa KH, Hansen JB, Myrhe ES Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans. Am J Clin Nutr. 1998 ; 68: 52-59.
41. Howe PR Dietary fats and hypertension. Ann N Y Acad Sci. 1997 ; 827: 339-352.
42. Kris-Etherton Pm, Harris WS, Appel LJ Fish consumption, fish oil, ω-3 fatty acids, and cardiovascular disease. Arterioscler Thromb Vasc Biol. 2003 ; 23: 20-31.