Microglia are required for protection against lethal coronavirus encephalitis in mice

Journal of Clinical Investigation

Volumn 128, Issue 3, 2018, Pages 931-943

  Wheeler, D Lori ^a   Sariol, Alan ^a   Meyerholz, David K ^b   Perlman, Stanley ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' DEAMINO 3' MORPHOLINOOXAUNOMYCIN; ALLOGRAFT INFLAMMATORY FACTOR 1; BETA INTERFERON; CARBON TETRACHLORIDE; GAMMA INTERFERON; GENOMIC RNA; IFIT1 PROTEIN; INTERFERON; INTERLEUKIN 6; MESSENGER RNA; OAS2 PROTEIN; PATTERN RECOGNITION RECEPTOR; PROTEIN; RANTES; UNCLASSIFIED DRUG; VIRUS RNA; CSF1R PROTEIN, MOUSE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; ORGANIC COMPOUND; PLX5622;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CORONAVIRUS ENCEPHALITIS; FLOW CYTOMETRY; GENE EXPRESSION; INFECTION; INFLAMMATORY CELL; LYMPHOCYTE COUNT; MICROARRAY ANALYSIS; MICROGLIA; MORTALITY RATE; MOUSE; MURINE HEPATITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SURVIVAL RATE; T LYMPHOCYTE; UPREGULATION; VIRAL CLEARANCE; VIRUS ENCEPHALITIS; VIRUS LOAD; VIRUS REPLICATION; ADAPTIVE IMMUNITY; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; C57BL MOUSE; CELL PROLIFERATION; CORONAVIRUS INFECTION; CYTOLOGY; ENCEPHALITIS; GENE EXPRESSION PROFILING; IMMUNOLOGY; INNATE IMMUNITY; MACROPHAGE; MALE; NERVE CELL NETWORK; OLFACTORY BULB; TRANSGENIC MOUSE; VIROLOGY;

ADAPTIVE IMMUNITY; ANIMALS; BRAIN; CELL PROLIFERATION; CORONAVIRUS INFECTIONS; ENCEPHALITIS; GENE EXPRESSION PROFILING; IMMUNITY, INNATE; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MURINE HEPATITIS VIRUS; NERVE NET; OLFACTORY BULB; ORGANIC CHEMICALS; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; T-LYMPHOCYTES;

EID: 85042749897     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI97229     Document Type: Article

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