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Volumn 142, Issue 3, 2018, Pages 321-346

Updated molecular testing guideline for the selection of lung cancer patients for treatment with targeted tyrosine kinase inhibitors guideline from the college of American pathologists, the international association for the study of lung cancer, and the association for molecular pathology

(22)  Lindeman, Neal I a   Cagle, Philip T c   Aisner, Dara L d   Arcila, Maria E e   Beasley, Mary Beth g   Bernicker, Eric H b   Colasacco, Carol h   Dacic, Sanja i   Hirsch, Fred R j   Kerr, Keith k   Kwiatkowski, David J a   Ladanyi, Marc f   Nowak, Jan A l   Sholl, Lynette a   Temple Smolkin, Robyn m   Solomon, Benjamin n   Souter, Lesley H s   Thunnissen, Erik o   Tsao, Ming S p   Ventura, Christina B h   more..


Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 85042667463     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: 10.5858/arpa.2017-0388-CP     Document Type: Conference Paper
Times cited : (613)

References (263)
  • 1
    • 84879635389 scopus 로고    scopus 로고
    • Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists International Association for the Study of Lung Cancer and Association for Molecular Pathology
    • Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. Arch Pathol Lab Med. 2013;137(6):828-860.
    • (2013) Arch Pathol Lab Med , vol.137 , Issue.6 , pp. 828-860
    • Lindeman, N.I.1    Cagle, P.T.2    Beasley, M.B.3
  • 2
    • 84880917028 scopus 로고    scopus 로고
    • Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
    • Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Thorac Oncol. 2013;8(7):823-859.
    • (2013) J Thorac Oncol , vol.8 , Issue.7 , pp. 823-859
    • Lindeman, N.I.1    Cagle, P.T.2    Beasley, M.B.3
  • 3
    • 84879290901 scopus 로고    scopus 로고
    • Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
    • Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Mol Diagn. 2013;15(4):415-453.
    • (2013) J Mol Diagn , vol.15 , Issue.4 , pp. 415-453
    • Lindeman, N.I.1    Cagle, P.T.2    Beasley, M.B.3
  • 4
    • 84911866971 scopus 로고    scopus 로고
    • Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology guideline
    • Leighl NB, Rekhtman N, Biermann WA, et al. Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology guideline. J Clin Oncol. 2014;32(32):3673-3679.
    • (2014) J Clin Oncol , vol.32 , Issue.32 , pp. 3673-3679
    • Leighl, N.B.1    Rekhtman, N.2    Biermann, W.A.3
  • 6
    • 84888206509 scopus 로고    scopus 로고
    • SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2013
    • Camps C, Felip E, Garcia-Campelo R, Trigo JM, Garrido P. SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2013. Clin Transl Oncol. 2013;15(12):977-984.
    • (2013) Clin Transl Oncol , vol.15 , Issue.12 , pp. 977-984
    • Camps, C.1    Felip, E.2    Garcia-Campelo, R.3    Trigo, J.M.4    Garrido, P.5
  • 7
    • 84896939264 scopus 로고    scopus 로고
    • National Working Group Meeting on ALK diagnostics in lung cancer
    • Cooper W, Fox S, O'Toole S, et al. National Working Group Meeting on ALK diagnostics in lung cancer. Asia Pac J Clin Oncol. 2014;10(suppl):211-217.
    • (2014) Asia Pac J Clin Oncol , vol.10 , pp. 211-217
    • Cooper, W.1    Fox, S.2    O'Toole, S.3
  • 8
    • 84958983242 scopus 로고    scopus 로고
    • Diagnostic procedures for non-small-cell lung cancer (NSCLC): Recommendations of the European Expert Group
    • Dietel M, Bubendorf L, Dingemans AM, et al. Diagnostic procedures for non-small-cell lung cancer (NSCLC): recommendations of the European Expert Group. Thorax. 2016;71(2):177-184.
    • (2016) Thorax , vol.71 , Issue.2 , pp. 177-184
    • Dietel, M.1    Bubendorf, L.2    Dingemans, A.M.3
  • 9
    • 84930520177 scopus 로고    scopus 로고
    • Validation of new cancer biomarkers: A position statement from the European group on tumor markers
    • Duffy MJ, Sturgeon CM, Soletormos G, et al. Validation of new cancer biomarkers: a position statement from the European group on tumor markers. Clin Chem. 2015;61(6):809-820.
    • (2015) Clin Chem , vol.61 , Issue.6 , pp. 809-820
    • Duffy, M.J.1    Sturgeon, C.M.2    Soletormos, G.3
  • 10
    • 84922463727 scopus 로고    scopus 로고
    • Biomarker testing in advanced nonsmall-cell lung cancer: A National Consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology
    • Felip E, Concha A, de Castro J, et al. Biomarker testing in advanced nonsmall-cell lung cancer: a National Consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology. Clin Transl Oncol. 2015;17(2): 103-112.
    • (2015) Clin Transl Oncol , vol.17 , Issue.2 , pp. 103-112
    • Felip, E.1    Concha, A.2    De Castro, J.3
  • 11
    • 84951274994 scopus 로고    scopus 로고
    • SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2015
    • Garcia-Campelo R, Bernabe R, Cobo M, et al. SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2015. Clin Transl Oncol. 2015;17(12):1020-1029.
    • (2015) Clin Transl Oncol , vol.17 , Issue.12 , pp. 1020-1029
    • Garcia-Campelo, R.1    Bernabe, R.2    Cobo, M.3
  • 12
    • 84941421849 scopus 로고    scopus 로고
    • Treatment of elderly patients with non-small-cell lung cancer: Results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology
    • Gridelli C, Balducci L, Ciardiello F, et al. Treatment of elderly patients with non-small-cell lung cancer: results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology. Clin Lung Cancer. 2015;16(5):325-333.
    • (2015) Clin Lung Cancer , vol.16 , Issue.5 , pp. 325-333
    • Gridelli, C.1    Balducci, L.2    Ciardiello, F.3
  • 13
    • 84991276196 scopus 로고    scopus 로고
    • The spectrum of clinical utilities in molecular pathology testing procedures for inherited conditions and cancer: A report of the Association for Molecular Pathology
    • Joseph L, Cankovic M, Caughron S, et al. The spectrum of clinical utilities in molecular pathology testing procedures for inherited conditions and cancer: a report of the Association for Molecular Pathology. J Mol Diagn. 2016;18(5):605-619.
    • (2016) J Mol Diagn , vol.18 , Issue.5 , pp. 605-619
    • Joseph, L.1    Cankovic, M.2    Caughron, S.3
  • 14
    • 84894611641 scopus 로고    scopus 로고
    • Guideline recommendations for testing of ALK gene rearrangement in lung cancer: A proposal of the Korean Cardiopulmonary Pathology Study Group
    • Kim H, Shim HS, Kim L, et al. Guideline recommendations for testing of ALK gene rearrangement in lung cancer: a proposal of the Korean Cardiopulmonary Pathology Study Group. Korean J Pathol. 2014;48(1):1-9.
    • (2014) Korean J Pathol , vol.48 , Issue.1 , pp. 1-9
    • Kim, H.1    Shim, H.S.2    Kim, L.3
  • 15
    • 84906860520 scopus 로고    scopus 로고
    • Second ESMO consensus conference on lung cancer: Pathology and molecular biomarkers for non-smallcell lung cancer
    • Kerr KM, Bubendorf L, Edelman MJ, et al. Second ESMO consensus conference on lung cancer: pathology and molecular biomarkers for non-smallcell lung cancer. Ann Oncol. 2014;25(9):1681-1690.
    • (2014) Ann Oncol , vol.25 , Issue.9 , pp. 1681-1690
    • Kerr, K.M.1    Bubendorf, L.2    Edelman, M.J.3
  • 16
    • 84992073509 scopus 로고    scopus 로고
    • Utilization of ancillary studies in the cytologic diagnosis of respiratory lesions: The Papanicolaou Society of Cytopathology consensus recommendations for respiratory cytology
    • Layfield LJ, Roy-Chowdhuri S, Baloch Z, et al. Utilization of ancillary studies in the cytologic diagnosis of respiratory lesions: the Papanicolaou Society of Cytopathology consensus recommendations for respiratory cytology. Diagn Cytopathol. 2016;44(12):1000-1009.
    • (2016) Diagn Cytopathol , vol.44 , Issue.12 , pp. 1000-1009
    • Layfield, L.J.1    Roy-Chowdhuri, S.2    Baloch, Z.3
  • 17
    • 85006371175 scopus 로고    scopus 로고
    • Standards and guidelines for the interpretation and reporting of sequence variants in cancer: A joint consensus recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists
    • Li MM, Datto M, Duncavage EJ, et al. Standards and guidelines for the interpretation and reporting of sequence variants in cancer: a joint consensus recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists. J Mol Diagn. 2017; 19(1):4-23.
    • (2017) J Mol Diagn , vol.19 , Issue.1 , pp. 4-23
    • Li, M.M.1    Datto, M.2    Duncavage, E.J.3
  • 18
    • 84925457305 scopus 로고    scopus 로고
    • Genomics-based earlyphase clinical trials in oncology: Recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies
    • Liu SV, Miller VA, Lobbezoo MW, Giaccone G. Genomics-based earlyphase clinical trials in oncology: recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies. Eur J Cancer. 2014;50(16):2747-2751.
    • (2014) Eur J Cancer , vol.50 , Issue.16 , pp. 2747-2751
    • Liu, S.V.1    Miller, V.A.2    Lobbezoo, M.W.3    Giaccone, G.4
  • 19
    • 84974652861 scopus 로고    scopus 로고
    • Canadian consensus: Inhibition of ALK-positive tumours in advanced non-small-cell lung cancer
    • Melosky B, Agulnik J, Albadine R, et al. Canadian consensus: inhibition of ALK-positive tumours in advanced non-small-cell lung cancer. Curr Oncol. 2016; 23(3):196-200.
    • (2016) Curr Oncol , vol.23 , Issue.3 , pp. 196-200
    • Melosky, B.1    Agulnik, J.2    Albadine, R.3
  • 20
    • 84940451900 scopus 로고    scopus 로고
    • Biological marker analysis as part of the CIBERES-RTIC Cancer-SEPAR Strategic Project on Lung Cancer
    • Monso E, Montuenga LM, Sanchez de Cos J, Villena C; Lung Cancer CIBERES-RTICC-SEPAR-Plataforma Biobanco Pulmonar. Biological marker analysis as part of the CIBERES-RTIC Cancer-SEPAR Strategic Project on Lung Cancer. Arch Bronconeumol. 2015;51(9):462-467.
    • (2015) Arch Bronconeumol , vol.51 , Issue.9 , pp. 462-467
    • Monso, E.1    Montuenga, L.M.2    Sanchez De Cos, J.3    Villena, C.4
  • 21
    • 85000814784 scopus 로고    scopus 로고
    • Recommendations of the Austrian Working Group on Pulmonary Pathology and Oncology for predictive molecular and immunohistochemical testing in non-small cell lung cancer
    • Popper HH, Gruber-Mosenbacher U, Hutarew G, et al. Recommendations of the Austrian Working Group on Pulmonary Pathology and Oncology for predictive molecular and immunohistochemical testing in non-small cell lung cancer. Memo. 2016;9(4):191-200.
    • (2016) Memo , vol.9 , Issue.4 , pp. 191-200
    • Popper, H.H.1    Gruber-Mosenbacher, U.2    Hutarew, G.3
  • 22
    • 85012064093 scopus 로고    scopus 로고
    • Molecular biomarkers for the evaluation of colorectal cancer: Guideline from the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology
    • Sepulveda AR, Hamilton SR, Allegra CJ, et al. Molecular biomarkers for the evaluation of colorectal cancer: guideline from the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology. J Clin Oncol. 2017; 35(13):1453-1486.
    • (2017) J Clin Oncol , vol.35 , Issue.13 , pp. 1453-1486
    • Sepulveda, A.R.1    Hamilton, S.R.2    Allegra, C.J.3
  • 23
    • 84927693108 scopus 로고    scopus 로고
    • Guideline for the acquisition and preparation of conventional and endobronchial ultrasoundguided transbronchial needle aspiration specimens for the diagnosis and molecular testing of patients with known or suspected lung cancer
    • van der Heijden EH, Casal RF, Trisolini R, et al. Guideline for the acquisition and preparation of conventional and endobronchial ultrasoundguided transbronchial needle aspiration specimens for the diagnosis and molecular testing of patients with known or suspected lung cancer. Respiration. 2014;88(6):500-517.
    • (2014) Respiration , vol.88 , Issue.6 , pp. 500-517
    • Van Der Heijden, E.H.1    Casal, R.F.2    Trisolini, R.3
  • 24
    • 85027217943 scopus 로고    scopus 로고
    • Executive summary of the SEPAR recommendations for the diagnosis and treatment of nonsmall cell lung cancer
    • Villar Alvarez F, Muguruza Trueba I, Belda Sanchis J, et al. Executive summary of the SEPAR recommendations for the diagnosis and treatment of nonsmall cell lung cancer. Arch Bronconeumol. 2016;52(7):378-388.
    • (2016) Arch Bronconeumol , vol.52 , Issue.7 , pp. 378-388
    • Villar Alvarez, F.1    Muguruza Trueba, I.2    Belda Sanchis, J.3
  • 25
    • 84998611075 scopus 로고    scopus 로고
    • ALK-testing in non-small cell lung cancer (NSCLC): Immunohistochemistry (IHC) and/or fluorescence in-situ hybridisation (FISH)?: Statement of the Germany Society for Pathology (DGP) and the Working Group Thoracic Oncology (AIO) of the German Cancer Society e.V
    • Stellungnahme der Deutschen Gesellschaft fur Pathologie und der AG Thorakale Onkologie der Arbeitsgemeinschaft Onkologie/Deutsche Krebsgesellschaft e.V.)
    • von Laffert M, Schirmacher P, Warth A, et al. ALK-testing in non-small cell lung cancer (NSCLC): immunohistochemistry (IHC) and/or fluorescence in-situ hybridisation (FISH)?: statement of the Germany Society for Pathology (DGP) and the Working Group Thoracic Oncology (AIO) of the German Cancer Society e.V. (Stellungnahme der Deutschen Gesellschaft fur Pathologie und der AG Thorakale Onkologie der Arbeitsgemeinschaft Onkologie/Deutsche Krebsgesellschaft e.V.). Lung Cancer. 2017;103:1-5.
    • (2017) Lung Cancer , vol.103 , pp. 1-5
    • Von Laffert, M.1    Schirmacher, P.2    Warth, A.3
  • 26
    • 84927935781 scopus 로고    scopus 로고
    • Scottish Intercollegiate Guidelines Network (SIGN). Edinburgh: SIGN; 2014. SIGN publication no. 137 Accessed June 12, 2017
    • Scottish Intercollegiate Guidelines Network (SIGN). Management of lung cancer. Edinburgh: SIGN; 2014. SIGN publication no. 137. http://www.sign.ac. uk. Accessed June 12, 2017.
    • Management of Lung Cancer
  • 28
    • 84874606355 scopus 로고    scopus 로고
    • EGFR mutation testing in lung cancer: A review of available methods and their use for analysis of tumour tissue and cytology samples
    • Ellison G, Zhu G, Moulis A, Dearden S, Speake G, McCormack R. EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples. J Clin Pathol. 2013;66(2):79-89.
    • (2013) J Clin Pathol , vol.66 , Issue.2 , pp. 79-89
    • Ellison, G.1    Zhu, G.2    Moulis, A.3    Dearden, S.4    Speake, G.5    McCormack, R.6
  • 29
    • 77954224784 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer
    • Kitamura A, Hosoda W, Sasaki E, Mitsudomi T, Yatabe Y. Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer. Clin Cancer Res. 2010;16(13):3349-3355.
    • (2010) Clin Cancer Res , vol.16 , Issue.13 , pp. 3349-3355
    • Kitamura, A.1    Hosoda, W.2    Sasaki, E.3    Mitsudomi, T.4    Yatabe, Y.5
  • 30
    • 84863338079 scopus 로고    scopus 로고
    • ROS1 rearrangements define a unique molecular class of lung cancers
    • Bergethon K, Shaw AT, Ou SH, et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol. 2012;30(8):863-870.
    • (2012) J Clin Oncol , vol.30 , Issue.8 , pp. 863-870
    • Bergethon, K.1    Shaw, A.T.2    Ou, S.H.3
  • 31
    • 84886545743 scopus 로고    scopus 로고
    • Clinicopathologic analysis of ROS1-rearranged non-small-cell lung cancer and proposal of a diagnostic algorithm
    • Go H, Kim DW, Kim D, et al. Clinicopathologic analysis of ROS1-rearranged non-small-cell lung cancer and proposal of a diagnostic algorithm. J Thorac Oncol. 2013;8(11):1445-1450.
    • (2013) J Thorac Oncol , vol.8 , Issue.11 , pp. 1445-1450
    • Go, H.1    Kim, D.W.2    Kim, D.3
  • 32
    • 84927139647 scopus 로고    scopus 로고
    • Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: Results from the EUROS1 cohort
    • Mazieres J, Zalcman G, Crino L, et al. Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort. J Clin Oncol. 2015;33(9):992-999.
    • (2015) J Clin Oncol , vol.33 , Issue.9 , pp. 992-999
    • Mazieres, J.1    Zalcman, G.2    Crino, L.3
  • 33
    • 84911372597 scopus 로고    scopus 로고
    • Crizotinib in ROS1-rearranged non-smallcell lung cancer
    • Shaw AT, Ou SH, Bang YJ, et al. Crizotinib in ROS1-rearranged non-smallcell lung cancer. N Engl J Med. 2014;371(21):1963-1971.
    • (2014) N Engl J Med , vol.371 , Issue.21 , pp. 1963-1971
    • Shaw, A.T.1    Ou, S.H.2    Bang, Y.J.3
  • 34
    • 84883444507 scopus 로고    scopus 로고
    • ROS1 fusions in Chinese patients with non-smallcell lung cancer
    • Cai W, Li X, Su C, et al. ROS1 fusions in Chinese patients with non-smallcell lung cancer. Ann Oncol. 2013;24(7):1822-1827.
    • (2013) Ann Oncol , vol.24 , Issue.7 , pp. 1822-1827
    • Cai, W.1    Li, X.2    Su, C.3
  • 35
    • 84905815103 scopus 로고    scopus 로고
    • Clinical and the prognostic characteristics of lung adenocarcinoma patients with ROS1 fusion in comparison with other driver mutations in East Asian populations
    • Chen YF, Hsieh MS, Wu SG, et al. Clinical and the prognostic characteristics of lung adenocarcinoma patients with ROS1 fusion in comparison with other driver mutations in East Asian populations. J Thorac Oncol. 2014;9(8): 1171-1179.
    • (2014) J Thorac Oncol , vol.9 , Issue.8 , pp. 1171-1179
    • Chen, Y.F.1    Hsieh, M.S.2    Wu, S.G.3
  • 36
    • 84904384871 scopus 로고    scopus 로고
    • ROS1 expression and translocations in non-small-cell lung cancer: Clinicopathological analysis of 1478 cases
    • Warth A, Muley T, Dienemann H, et al. ROS1 expression and translocations in non-small-cell lung cancer: clinicopathological analysis of 1478 cases. Histopathology. 2014;65(2):187-194.
    • (2014) Histopathology , vol.65 , Issue.2 , pp. 187-194
    • Warth, A.1    Muley, T.2    Dienemann, H.3
  • 37
    • 84926518178 scopus 로고    scopus 로고
    • Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma
    • Lee SE, Lee B, Hong M, et al. Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma. Mod Pathol. 2015;28(4):468-479.
    • (2015) Mod Pathol , vol.28 , Issue.4 , pp. 468-479
    • Lee, S.E.1    Lee, B.2    Hong, M.3
  • 38
    • 84929589877 scopus 로고    scopus 로고
    • ROS1 rearrangements in lung adenocarcinoma: Prognostic impact, therapeutic options and genetic variability
    • Scheffler M, Schultheis A, Teixido C, et al. ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability. Oncotarget. 2015;6(12):10577-10585.
    • (2015) Oncotarget , vol.6 , Issue.12 , pp. 10577-10585
    • Scheffler, M.1    Schultheis, A.2    Teixido, C.3
  • 39
    • 84883343307 scopus 로고    scopus 로고
    • The frequency and impact of ROS1 rearrangement on clinical outcomes in never smokers with lung adenocarcinoma
    • Kim HR, Lim SM, Kim HJ, et al. The frequency and impact of ROS1 rearrangement on clinical outcomes in never smokers with lung adenocarcinoma. Ann Oncol. 2013;24(9):2364-2370.
    • (2013) Ann Oncol , vol.24 , Issue.9 , pp. 2364-2370
    • Kim, H.R.1    Lim, S.M.2    Kim, H.J.3
  • 41
    • 84870894199 scopus 로고    scopus 로고
    • Food U.S. Drug Administration. Accessed June 1.2. 2017
    • US Food and Drug Administration. XALKORI prescribing information. http://www.accessdata.fda.gov/drugsatfda-docs/label/2016/202570s016lbl.pdf. Accessed June 12, 2017.
    • XALKORI Prescribing Information
  • 42
    • 84904910906 scopus 로고    scopus 로고
    • Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements
    • Cha YJ, Lee JS, Kim HR, et al. Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements. PLoS One. 2014;9(7):e103333. doi:10.1371/journal.pone.0103333.
    • (2014) PLoS One , vol.9 , Issue.7 , pp. e103333
    • Cha, Y.J.1    Lee, J.S.2    Kim, H.R.3
  • 43
    • 84892875156 scopus 로고    scopus 로고
    • On the relevance of a testing algorithm for the detection of ROS1-rearranged lung adenocarcinomas
    • Mescam-Mancini L, Lantuejoul S, Moro-Sibilot D, et al. On the relevance of a testing algorithm for the detection of ROS1-rearranged lung adenocarcinomas. Lung Cancer. 2014;83(2):168-173.
    • (2014) Lung Cancer , vol.83 , Issue.2 , pp. 168-173
    • Mescam-Mancini, L.1    Lantuejoul, S.2    Moro-Sibilot, D.3
  • 44
    • 84884515755 scopus 로고    scopus 로고
    • ROS1 immunohistochemistry for detection of ROS1-rearranged lung adenocarcinomas
    • Sholl LM, Sun H, Butaney M, et al. ROS1 immunohistochemistry for detection of ROS1-rearranged lung adenocarcinomas. Am J Surg Pathol. 2013; 37(9):1441-1449.
    • (2013) Am J Surg Pathol , vol.37 , Issue.9 , pp. 1441-1449
    • Sholl, L.M.1    Sun, H.2    Butaney, M.3
  • 45
    • 84899989532 scopus 로고    scopus 로고
    • Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers
    • Yoshida A, Tsuta K, Wakai S, et al. Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers. Mod Pathol. 2014;27(5):711-720.
    • (2014) Mod Pathol , vol.27 , Issue.5 , pp. 711-720
    • Yoshida, A.1    Tsuta, K.2    Wakai, S.3
  • 46
    • 84922975873 scopus 로고    scopus 로고
    • ROS1 immunohistochemistry among major genotypes of non-small-cell lung cancer
    • Boyle TA, Masago K, Ellison KE, Yatabe Y, Hirsch FR. ROS1 immunohistochemistry among major genotypes of non-small-cell lung cancer. Clin Lung Cancer. 2015;16(2):106-111.
    • (2015) Clin Lung Cancer , vol.16 , Issue.2 , pp. 106-111
    • Boyle, T.A.1    Masago, K.2    Ellison, K.E.3    Yatabe, Y.4    Hirsch, F.R.5
  • 47
    • 84924310226 scopus 로고    scopus 로고
    • Detection of ROS1 gene rearrangement in lung adenocarcinoma: Comparison of IHC FISH and real-time RT-PCR
    • Shan L, Lian F, Guo L, et al. Detection of ROS1 gene rearrangement in lung adenocarcinoma: comparison of IHC, FISH and real-time RT-PCR. PLoS One. 2015;10(3):e0120422. doi:10.1371/journal.pone.0120422.
    • (2015) PLoS One , vol.10 , Issue.3 , pp. e0120422
    • Shan, L.1    Lian, F.2    Guo, L.3
  • 48
    • 85011306206 scopus 로고    scopus 로고
    • High prevalence of concomitant oncogene mutations in prospectively identified patients with ROS1-positive metastatic lung cancer
    • Wiesweg M, Eberhardt WE, Reis H, et al. High prevalence of concomitant oncogene mutations in prospectively identified patients with ROS1-positive metastatic lung cancer. J Thorac Oncol. 2017;12(1):54-64.
    • (2017) J Thorac Oncol , vol.12 , Issue.1 , pp. 54-64
    • Wiesweg, M.1    Eberhardt, W.E.2    Reis, H.3
  • 49
    • 85019830463 scopus 로고    scopus 로고
    • Identification of five driver gene mutations in patients with treatment-naive lung adenocarcinoma in Taiwan
    • Hsu KH, Ho CC, Hsia TC, et al. Identification of five driver gene mutations in patients with treatment-naive lung adenocarcinoma in Taiwan. PLoS One. 2015;10(3):e0120852. doi:10.1371/journal.pone.0120852.
    • (2015) PLoS One , vol.10 , Issue.3 , pp. e0120852
    • Hsu, K.H.1    Ho, C.C.2    Hsia, T.C.3
  • 50
    • 84901826745 scopus 로고    scopus 로고
    • Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations
    • Kinno T, Tsuta K, Shiraishi K, et al. Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations. Ann Oncol. 2014;25(1): 138-142.
    • (2014) Ann Oncol , vol.25 , Issue.1 , pp. 138-142
    • Kinno, T.1    Tsuta, K.2    Shiraishi, K.3
  • 51
    • 84871095066 scopus 로고    scopus 로고
    • Frequency of well-identified oncogenic driver mutations in lung adenocarcinoma of smokers varies with histological subtypes and graduated smoking dose
    • Li H, Pan Y, Li Y, et al. Frequency of well-identified oncogenic driver mutations in lung adenocarcinoma of smokers varies with histological subtypes and graduated smoking dose. Lung Cancer. 2013;79(1):8-13.
    • (2013) Lung Cancer , vol.79 , Issue.1 , pp. 8-13
    • Li, H.1    Pan, Y.2    Li, Y.3
  • 52
    • 84901590009 scopus 로고    scopus 로고
    • Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: A comprehensive mutation profiling from 5125 Chinese cohorts
    • Li S, Li L, Zhu Y, et al. Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts. Br J Cancer. 2014;110(11):2812-2820.
    • (2014) Br J Cancer , vol.110 , Issue.11 , pp. 2812-2820
    • Li, S.1    Li, L.2    Zhu, Y.3
  • 53
    • 84883022821 scopus 로고    scopus 로고
    • Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer
    • Cardarella S, Ogino A, Nishino M, et al. Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. Clin Cancer Res. 2013;19(16):4532-4540.
    • (2013) Clin Cancer Res , vol.19 , Issue.16 , pp. 4532-4540
    • Cardarella, S.1    Ogino, A.2    Nishino, M.3
  • 54
    • 80053014471 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations
    • Marchetti A, Felicioni L, Malatesta S, et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. J Clin Oncol. 2011;29(26):3574-3579.
    • (2011) J Clin Oncol , vol.29 , Issue.26 , pp. 3574-3579
    • Marchetti, A.1    Felicioni, L.2    Malatesta, S.3
  • 55
    • 84896707216 scopus 로고    scopus 로고
    • BRAF-mutations in nonsmall cell lung cancer
    • Brustugun OT, Khattak AM, Tromborg AK, et al. BRAF-mutations in nonsmall cell lung cancer. Lung Cancer. 2014;84(1):36-38.
    • (2014) Lung Cancer , vol.84 , Issue.1 , pp. 36-38
    • Brustugun, O.T.1    Khattak, A.M.2    Tromborg, A.K.3
  • 56
    • 84964329499 scopus 로고    scopus 로고
    • Dabrafenib in patients with BRAF(V600E)-positive advanced non-small-cell lung cancer: A single-arm, multicentre, open-label, phase 2 trial
    • Planchard D, Kim TM, Mazieres J, et al. Dabrafenib in patients with BRAF(V600E)-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial. Lancet Oncol. 2016;17(5):642-650.
    • (2016) Lancet Oncol , vol.17 , Issue.5 , pp. 642-650
    • Planchard, D.1    Kim, T.M.2    Mazieres, J.3
  • 57
    • 84991059363 scopus 로고    scopus 로고
    • Dabrafenib plus trametinib in patients with previously treated BRAF(V600E)-mutant metastatic non-small cell lung cancer: An open-label, multicentre phase 2 trial
    • Planchard D, Besse B, Groen HJ, et al. Dabrafenib plus trametinib in patients with previously treated BRAF(V600E)-mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial. Lancet Oncol. 2016;17(7): 984-993.
    • (2016) Lancet Oncol , vol.17 , Issue.7 , pp. 984-993
    • Planchard, D.1    Besse, B.2    Groen, H.J.3
  • 58
    • 84874581453 scopus 로고    scopus 로고
    • Diagnostic value of immunohistochemistry for the detection of the BRAFV600E mutation in primary lung adenocarcinoma Caucasian patients
    • Ilie M, Long E, Hofman V, et al. Diagnostic value of immunohistochemistry for the detection of the BRAFV600E mutation in primary lung adenocarcinoma Caucasian patients. Ann Oncol. 2013;24(3):742-748.
    • (2013) Ann Oncol , vol.24 , Issue.3 , pp. 742-748
    • Ilie, M.1    Long, E.2    Hofman, V.3
  • 59
    • 84925714296 scopus 로고    scopus 로고
    • BRAF mutations in non-small-cell lung cancer
    • Smit E. BRAF mutations in non-small-cell lung cancer. J Thorac Oncol. 2014;9(11):1594-1595.
    • (2014) J Thorac Oncol , vol.9 , Issue.11 , pp. 1594-1595
    • Smit, E.1
  • 60
    • 84884413617 scopus 로고    scopus 로고
    • Usefulness of immunohistochemistry for the detection of the BRAF V600E mutation in Japanese lung adenocarcinoma
    • Sasaki H, Shimizu S, Tani Y, et al. Usefulness of immunohistochemistry for the detection of the BRAF V600E mutation in Japanese lung adenocarcinoma. Lung Cancer. 2013;82(1):51-54.
    • (2013) Lung Cancer , vol.82 , Issue.1 , pp. 51-54
    • Sasaki, H.1    Shimizu, S.2    Tani, Y.3
  • 61
    • 84922540993 scopus 로고    scopus 로고
    • Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK "borderline"-positive rearrangements or a high copy number: A potential major issue for anti-ALK therapeutic strategies
    • Ilie MI, Bence C, Hofman V, et al. Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK "borderline"-positive rearrangements or a high copy number: a potential major issue for anti-ALK therapeutic strategies. Ann Oncol. 2015;26(1):238-244.
    • (2015) Ann Oncol , vol.26 , Issue.1 , pp. 238-244
    • Ilie, M.I.1    Bence, C.2    Hofman, V.3
  • 62
    • 84870748688 scopus 로고    scopus 로고
    • RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
    • Wang R, Hu H, Pan Y, et al. RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. J Clin Oncol. 2012; 30(35):4352-4359.
    • (2012) J Clin Oncol , vol.30 , Issue.35 , pp. 4352-4359
    • Wang, R.1    Hu, H.2    Pan, Y.3
  • 63
    • 84926408835 scopus 로고    scopus 로고
    • Clinical and prognostic implications of RET rearrangements in metastatic lung adenocarcinoma patients with malignant pleural effusion
    • Tsai TH, Wu SG, Hsieh MS, Yu CJ, Yang JC, Shih JY. Clinical and prognostic implications of RET rearrangements in metastatic lung adenocarcinoma patients with malignant pleural effusion. Lung Cancer. 2015;88(2):208-214.
    • (2015) Lung Cancer , vol.88 , Issue.2 , pp. 208-214
    • Tsai, T.H.1    Wu, S.G.2    Hsieh, M.S.3    Yu, C.J.4    Yang, J.C.5    Shih, J.Y.6
  • 64
    • 84857929267 scopus 로고    scopus 로고
    • KIF5B-RET fusions in lung adenocarcinoma
    • Kohno T, Ichikawa H, Totoki Y, et al. KIF5B-RET fusions in lung adenocarcinoma. Nat Med. 2012;18(3):375-377.
    • (2012) Nat Med , vol.18 , Issue.3 , pp. 375-377
    • Kohno, T.1    Ichikawa, H.2    Totoki, Y.3
  • 65
    • 84857985225 scopus 로고    scopus 로고
    • RET ROS1 and ALK fusions in lung cancer
    • Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med. 2012;18(3):378-381.
    • (2012) Nat Med , vol.18 , Issue.3 , pp. 378-381
    • Takeuchi, K.1    Soda, M.2    Togashi, Y.3
  • 66
    • 84871181092 scopus 로고    scopus 로고
    • Identification of KIF5B-RET and GOPCROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions
    • Suehara Y, Arcila M,Wang L, et al. Identification of KIF5B-RET and GOPCROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions. Clin Cancer Res. 2012;18(24):6599-6608.
    • (2012) Clin Cancer Res , vol.18 , Issue.24 , pp. 6599-6608
    • Suehara, Y.1    Arcila Mwang, L.2
  • 67
    • 84862776857 scopus 로고    scopus 로고
    • Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
    • Lipson D, Capelletti M, Yelensky R, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med. 2012;18(3): 382-384.
    • (2012) Nat Med , vol.18 , Issue.3 , pp. 382-384
    • Lipson, D.1    Capelletti, M.2    Yelensky, R.3
  • 68
    • 85003445176 scopus 로고    scopus 로고
    • Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): An openlabel, multicentre phase 2 trial
    • Yoh K, Seto T, Satouchi M, et al. Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an openlabel, multicentre phase 2 trial. Lancet Respir Med. 2017;5(1):42-50.
    • (2017) Lancet Respir Med , vol.5 , Issue.1 , pp. 42-50
    • Yoh, K.1    Seto, T.2    Satouchi, M.3
  • 69
    • 85003533203 scopus 로고    scopus 로고
    • Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: An open-label, singlecentre, phase 2, single-arm trial
    • Drilon A, Rekhtman N, Arcila M, et al. Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, singlecentre, phase 2, single-arm trial. Lancet Oncol. 2016;17(12):1653-1660.
    • (2016) Lancet Oncol , vol.17 , Issue.12 , pp. 1653-1660
    • Drilon, A.1    Rekhtman, N.2    Arcila, M.3
  • 70
    • 85018282184 scopus 로고    scopus 로고
    • Targeting RET in patients with RETrearranged lung cancers: Results from the global, multicenter RET registry
    • Gautschi O, Milia J, Filleron T, et al. Targeting RET in patients with RETrearranged lung cancers: results from the global, multicenter RET registry. J Clin Oncol. 2017;35(13):1403-1410.
    • (2017) J Clin Oncol , vol.35 , Issue.13 , pp. 1403-1410
    • Gautschi, O.1    Milia, J.2    Filleron, T.3
  • 71
    • 84876383602 scopus 로고    scopus 로고
    • A patient with lung adenocarcinoma and RET fusion treated with vandetanib
    • Gautschi O, Zander T, Keller FA, et al. A patient with lung adenocarcinoma and RET fusion treated with vandetanib. J Thorac Oncol. 2013;8(5):e43-e44.
    • (2013) J Thorac Oncol , vol.8 , Issue.5 , pp. e43-e44
    • Gautschi, O.1    Zander, T.2    Keller, F.A.3
  • 72
    • 84878858856 scopus 로고    scopus 로고
    • Response to cabozantinib in patients with RET fusion-positive lung adenocarcinomas
    • Drilon A, Wang L, Hasanovic A, et al. Response to cabozantinib in patients with RET fusion-positive lung adenocarcinomas. Cancer Discov. 2013; 3(6):630-635.
    • (2013) Cancer Discov , vol.3 , Issue.6 , pp. 630-635
    • Drilon, A.1    Wang, L.2    Hasanovic, A.3
  • 73
    • 84897096705 scopus 로고    scopus 로고
    • Prognostic and predictive biomarkers in lung cancer: A review
    • Thunnissen E, van der Oord K, den Bakker M. Prognostic and predictive biomarkers in lung cancer: a review. Virchows Arch. 2014;464(3):347-358.
    • (2014) Virchows Arch , vol.464 , Issue.3 , pp. 347-358
    • Thunnissen, E.1    Van Der Oord, K.2    Den Bakker, M.3
  • 74
    • 84862812241 scopus 로고    scopus 로고
    • Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers
    • Li F, Feng Y, Fang R, et al. Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers. Cell Res. 2012;22(5): 928-931.
    • (2012) Cell Res , vol.22 , Issue.5 , pp. 928-931
    • Li, F.1    Feng, Y.2    Fang, R.3
  • 75
    • 84880681062 scopus 로고    scopus 로고
    • RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer
    • Sasaki H, Shimizu S, Tani Y, et al. RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer. Cancer Med. 2012;1(1):68-75.
    • (2012) Cancer Med , vol.1 , Issue.1 , pp. 68-75
    • Sasaki, H.1    Shimizu, S.2    Tani, Y.3
  • 76
    • 84925582188 scopus 로고    scopus 로고
    • Anchored multiplex PCR for targeted next-generation sequencing
    • Zheng Z, Liebers M, Zhelyazkova B, et al. Anchored multiplex PCR for targeted next-generation sequencing. Nat Med. 2014;20(12):1479-1484.
    • (2014) Nat Med , vol.20 , Issue.12 , pp. 1479-1484
    • Zheng, Z.1    Liebers, M.2    Zhelyazkova, B.3
  • 77
    • 84864563569 scopus 로고    scopus 로고
    • HER-2/neu oncogene and estrogen receptor expression in non small cell lung cancer patients
    • Aleric I, Razumovic JJ, Koprivica B. HER-2/neu oncogene and estrogen receptor expression in non small cell lung cancer patients. Med Pregl. 2012; 65(5-6):210-215.
    • (2012) Med Pregl , vol.65 , Issue.5-6 , pp. 210-215
    • Aleric, I.1    Razumovic, J.J.2    Koprivica, B.3
  • 78
    • 77951246057 scopus 로고    scopus 로고
    • Prognostic significance of the C-ERBB-2 expression in Turkish non-small cell lung cancer patients
    • Calikusu Z, Yildirim Y, Akcali Z, Sakalli H, Bal N, Ozyilkan O. Prognostic significance of the C-erbB-2 expression in Turkish non-small cell lung cancer patients. Asian Pac J Cancer Prev. 2009;10(3):479-482.
    • (2009) Asian Pac J Cancer Prev , vol.10 , Issue.3 , pp. 479-482
    • Calikusu, Z.1    Yildirim, Y.2    Akcali, Z.3    Sakalli, H.4    Bal, N.5    Ozyilkan, O.6
  • 79
    • 78650459071 scopus 로고    scopus 로고
    • The role of human epidermal growth factor receptor 2 as a prognostic factor in lung cancer: A meta-analysis of published data
    • Liu L, Shao X, Gao W, et al. The role of human epidermal growth factor receptor 2 as a prognostic factor in lung cancer: a meta-analysis of published data. J Thorac Oncol. 2010;5(12):1922-1932.
    • (2010) J Thorac Oncol , vol.5 , Issue.12 , pp. 1922-1932
    • Liu, L.1    Shao, X.2    Gao, W.3
  • 80
    • 80052558779 scopus 로고    scopus 로고
    • Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers
    • Tomizawa K, Suda K, Onozato R, et al. Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers. Lung Cancer. 2011;74(1):139-144.
    • (2011) Lung Cancer , vol.74 , Issue.1 , pp. 139-144
    • Tomizawa, K.1    Suda, K.2    Onozato, R.3
  • 81
    • 84866360342 scopus 로고    scopus 로고
    • Prevalence, clinicopathologic associations, and molecular spectrum of ERBB2 (HER2) tyrosine kinase mutations in lung adenocarcinomas
    • Arcila ME, Chaft JE, Nafa K, et al. Prevalence, clinicopathologic associations, and molecular spectrum of ERBB2 (HER2) tyrosine kinase mutations in lung adenocarcinomas. Clin Cancer Res. 2012;18(18):4910-4918.
    • (2012) Clin Cancer Res , vol.18 , Issue.18 , pp. 4910-4918
    • Arcila, M.E.1    Chaft, J.E.2    Nafa, K.3
  • 82
    • 84926407151 scopus 로고    scopus 로고
    • HER2 status in lung adenocarcinoma: A comparison of immunohistochemistry, fluorescence in situ hybridization (FISH), dual-ISH, and gene mutations
    • Yoshizawa A, Sumiyoshi S, Sonobe M, et al. HER2 status in lung adenocarcinoma: a comparison of immunohistochemistry, fluorescence in situ hybridization (FISH), dual-ISH, and gene mutations. Lung Cancer. 2014;85(3): 373-378.
    • (2014) Lung Cancer , vol.85 , Issue.3 , pp. 373-378
    • Yoshizawa, A.1    Sumiyoshi, S.2    Sonobe, M.3
  • 83
    • 84939202466 scopus 로고    scopus 로고
    • Prevalence and clinicopathological characteristics of HER2 and BRAF mutation in Chinese patients with lung adenocarcinoma
    • Shan L, Qiu T, Ling Y, et al. Prevalence and clinicopathological characteristics of HER2 and BRAF mutation in Chinese patients with lung adenocarcinoma. PLoS One. 2015;10(6):e0130447. doi:10.1371/journal.pone. 0130447.
    • (2015) PLoS One , vol.10 , Issue.6 , pp. e0130447
    • Shan, L.1    Qiu, T.2    Ling, Y.3
  • 84
    • 84922262212 scopus 로고    scopus 로고
    • HER2 gene mutations in non-small cell lung carcinomas: Concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation
    • Suzuki M, Shiraishi K, Yoshida A, et al. HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation. Lung Cancer. 2015;87(1):14-22.
    • (2015) Lung Cancer , vol.87 , Issue.1 , pp. 14-22
    • Suzuki, M.1    Shiraishi, K.2    Yoshida, A.3
  • 85
    • 84946710397 scopus 로고    scopus 로고
    • Targeting HER2 aberrations as actionable drivers in lung cancers: Phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors
    • Kris MG, Camidge DR, Giaccone G, et al. Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors. Ann Oncol. 2015;26(7):1421-1427.
    • (2015) Ann Oncol , vol.26 , Issue.7 , pp. 1421-1427
    • Kris, M.G.1    Camidge, D.R.2    Giaccone, G.3
  • 86
    • 84655167862 scopus 로고    scopus 로고
    • Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains
    • Li C, Sun Y, Fang R, et al. Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains. J Thorac Oncol. 2012;7(1):85-89.
    • (2012) J Thorac Oncol , vol.7 , Issue.1 , pp. 85-89
    • Li, C.1    Sun, Y.2    Fang, R.3
  • 87
    • 0942287963 scopus 로고    scopus 로고
    • Randomized phase II trial of gemcitabine-cisplatin with or without trastuzumab in HER2-positive non-smallcell lung cancer
    • Gatzemeier U, Groth G, Butts C, et al. Randomized phase II trial of gemcitabine-cisplatin with or without trastuzumab in HER2-positive non-smallcell lung cancer. Ann Oncol. 2004;15(1):19-27.
    • (2004) Ann Oncol , vol.15 , Issue.1 , pp. 19-27
    • Gatzemeier, U.1    Groth, G.2    Butts, C.3
  • 88
    • 27644566209 scopus 로고    scopus 로고
    • Randomized phase II study of weekly docetaxel plus trastuzumab versus weekly paclitaxel plus trastuzumab in patients with previously untreated advanced nonsmall cell lung carcinoma
    • Krug LM, Miller VA, Patel J, et al. Randomized phase II study of weekly docetaxel plus trastuzumab versus weekly paclitaxel plus trastuzumab in patients with previously untreated advanced nonsmall cell lung carcinoma. Cancer. 2005; 104(10):2149-2155.
    • (2005) Cancer , vol.104 , Issue.10 , pp. 2149-2155
    • Krug, L.M.1    Miller, V.A.2    Patel, J.3
  • 89
    • 84962606011 scopus 로고    scopus 로고
    • HER2 amplification and HER2 mutation are distinct molecular targets in lung cancers
    • Li BT, Ross DS, Aisner DL, et al. HER2 amplification and HER2 mutation are distinct molecular targets in lung cancers. J Thorac Oncol. 2016;11(3):414-419.
    • (2016) J Thorac Oncol , vol.11 , Issue.3 , pp. 414-419
    • Li, B.T.1    Ross, D.S.2    Aisner, D.L.3
  • 90
    • 84867760241 scopus 로고    scopus 로고
    • HER2 amplification: A potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation
    • Takezawa K, Pirazzoli V, Arcila ME, et al. HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation. Cancer Discov. 2012; 2(10):922-933.
    • (2012) Cancer Discov , vol.2 , Issue.10 , pp. 922-933
    • Takezawa, K.1    Pirazzoli, V.2    Arcila, M.E.3
  • 91
    • 85017623620 scopus 로고    scopus 로고
    • ERBB2-mutated metastatic non-small cell lung cancer: Response and resistance to targeted therapies
    • Chuang JC, Stehr H, Liang Y, et al. ERBB2-mutated metastatic non-small cell lung cancer: response and resistance to targeted therapies. J Thorac Oncol. 2017;12(5):833-842.
    • (2017) J Thorac Oncol , vol.12 , Issue.5 , pp. 833-842
    • Chuang, J.C.1    Stehr, H.2    Liang, Y.3
  • 92
    • 84873415195 scopus 로고    scopus 로고
    • The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall cell lung cancer
    • Fiala O, Pesek M, Finek J, Benesova L, Belsanova B, Minarik M. The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall cell lung cancer. Cancer Genet. 2013;206(1-2):26-31.
    • (2013) Cancer Genet , vol.206 , Issue.1-2 , pp. 26-31
    • Fiala, O.1    Pesek, M.2    Finek, J.3    Benesova, L.4    Belsanova, B.5    Minarik, M.6
  • 93
    • 77955096407 scopus 로고    scopus 로고
    • KRAS mutations and resistance to EGFRTKIs treatment in patients with non-small cell lung cancer: A meta-analysis of 22 studies
    • Mao C, Qiu LX, Liao RY, et al. KRAS mutations and resistance to EGFRTKIs treatment in patients with non-small cell lung cancer: a meta-analysis of 22 studies. Lung Cancer. 2010;69(3):272-278.
    • (2010) Lung Cancer , vol.69 , Issue.3 , pp. 272-278
    • Mao, C.1    Qiu, L.X.2    Liao, R.Y.3
  • 94
    • 84878981521 scopus 로고    scopus 로고
    • Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: A systematic review with meta-analysis
    • Meng D, Yuan M, Li X, et al. Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: a systematic review with meta-analysis. Lung Cancer. 2013;81(1):1-10.
    • (2013) Lung Cancer , vol.81 , Issue.1 , pp. 1-10
    • Meng, D.1    Yuan, M.2    Li, X.3
  • 95
    • 84940110053 scopus 로고    scopus 로고
    • Profiling of oncogenic driver events in lung adenocarcinoma revealed MET mutation as independent prognostic factor
    • Yeung SF, Tong JH, Law PP, et al. Profiling of oncogenic driver events in lung adenocarcinoma revealed MET mutation as independent prognostic factor. J Thorac Oncol. 2015;10(9):1292-1300.
    • (2015) J Thorac Oncol , vol.10 , Issue.9 , pp. 1292-1300
    • Yeung, S.F.1    Tong, J.H.2    Law, P.P.3
  • 96
    • 73949154122 scopus 로고    scopus 로고
    • Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer
    • Leidner RS, Fu P, Clifford B, et al. Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer. J Clin Oncol. 2009;27(33):5620-5626.
    • (2009) J Clin Oncol , vol.27 , Issue.33 , pp. 5620-5626
    • Leidner, R.S.1    Fu, P.2    Clifford, B.3
  • 97
    • 78651087933 scopus 로고    scopus 로고
    • Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans
    • Reinersman JM, Johnson ML, Riely GJ, et al. Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans. J Thorac Oncol. 2011; 6(1):28-31.
    • (2011) J Thorac Oncol , vol.6 , Issue.1 , pp. 28-31
    • Reinersman, J.M.1    Johnson, M.L.2    Riely, G.J.3
  • 98
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97(5):339-346.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.5 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 99
    • 53249145767 scopus 로고    scopus 로고
    • Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma
    • Riely GJ, Kris MG, Rosenbaum D, et al. Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. Clin Cancer Res. 2008;14(18):5731-5734.
    • (2008) Clin Cancer Res , vol.14 , Issue.18 , pp. 5731-5734
    • Riely, G.J.1    Kris, M.G.2    Rosenbaum, D.3
  • 100
    • 84863273943 scopus 로고    scopus 로고
    • Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability
    • Thu KL, Vucic EA, Chari R, et al. Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability. PLoS One. 2012;7(3):e33003. doi:10.1371/journal. pone.0033003.
    • (2012) PLoS One , vol.7 , Issue.3 , pp. e33003
    • Thu, K.L.1    Vucic, E.A.2    Chari, R.3
  • 101
    • 79957905683 scopus 로고    scopus 로고
    • Genomic profiles specific to patient ethnicity in lung adenocarcinoma
    • Broet P, Dalmasso C, Tan EH, et al. Genomic profiles specific to patient ethnicity in lung adenocarcinoma. Clin Cancer Res. 2011;17(11):3542-3550.
    • (2011) Clin Cancer Res , vol.17 , Issue.11 , pp. 3542-3550
    • Broet, P.1    Dalmasso, C.2    Tan, E.H.3
  • 102
    • 84871720411 scopus 로고    scopus 로고
    • Selumetinib plus docetaxel for KRASmutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study
    • Janne PA, Shaw AT, Pereira JR, et al. Selumetinib plus docetaxel for KRASmutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study. Lancet Oncol. 2013;14(1):38-47.
    • (2013) Lancet Oncol , vol.14 , Issue.1 , pp. 38-47
    • Janne, P.A.1    Shaw, A.T.2    Pereira, J.R.3
  • 103
    • 85019402929 scopus 로고    scopus 로고
    • Selumetinib plus docetaxel compared with docetaxel alone and progression-free survival in patients with KRAS-mutant advanced non-small cell lung cancer: The SELECT-1 randomized clinical trial
    • Janne PA, van den Heuvel MM, Barlesi F, et al. Selumetinib plus docetaxel compared with docetaxel alone and progression-free survival in patients with KRAS-mutant advanced non-small cell lung cancer: the SELECT-1 randomized clinical trial. JAMA. 2017;317(18):1844-1853.
    • (2017) JAMA , vol.317 , Issue.18 , pp. 1844-1853
    • Janne, P.A.1    Van Den Heuvel, M.M.2    Barlesi, F.3
  • 104
    • 84964650469 scopus 로고    scopus 로고
    • Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer
    • Carter CA, Rajan A, Keen C, et al. Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer. Ann Oncol. 2016;27(4):693-699.
    • (2016) Ann Oncol , vol.27 , Issue.4 , pp. 693-699
    • Carter, C.A.1    Rajan, A.2    Keen, C.3
  • 105
    • 85016780747 scopus 로고    scopus 로고
    • Characteristics and outcomes of patients with lung cancer harboring multiple molecular alterations: Results from the IFCT study Biomarkers France
    • Guibert N, Barlesi F, Descourt R, et al. Characteristics and outcomes of patients with lung cancer harboring multiple molecular alterations: results from the IFCT study Biomarkers France. J Thorac Oncol. 2017;12(6):963-973.
    • (2017) J Thorac Oncol , vol.12 , Issue.6 , pp. 963-973
    • Guibert, N.1    Barlesi, F.2    Descourt, R.3
  • 106
    • 85006814980 scopus 로고    scopus 로고
    • Genetic heterogeneity of KRASmutated NSCLC: Co-occurrence of potentially targetable aberrations and evolutionary background [ASCO meeting abstract]
    • Scheffler M, Ihle MA, Hein R, et al. Genetic heterogeneity of KRASmutated NSCLC: co-occurrence of potentially targetable aberrations and evolutionary background [ASCO meeting abstract]. J Clin Oncol. 2016; 34(suppl):9018.
    • (2016) J Clin Oncol , vol.34 , pp. 9018
    • Scheffler, M.1    Ihle, M.A.2    Hein, R.3
  • 107
    • 84903380770 scopus 로고    scopus 로고
    • Prognostic value of MET gene copy number and protein expression in patients with surgically resected non-small cell lung cancer: A meta-analysis of published literatures
    • Guo B, Cen H, Tan X, Liu W, Ke Q. Prognostic value of MET gene copy number and protein expression in patients with surgically resected non-small cell lung cancer: a meta-analysis of published literatures. PLoS One. 2014;9(6): e99399. doi:10.1371/journal.pone.0099399.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e99399
    • Guo, B.1    Cen, H.2    Tan, X.3    Liu, W.4    Ke, Q.5
  • 108
    • 84896718478 scopus 로고    scopus 로고
    • MET gene copy number gain is an independent poor prognostic marker in Korean stage i lung adenocarcinomas
    • Jin Y, Sun PL, Kim H, et al. MET gene copy number gain is an independent poor prognostic marker in Korean stage I lung adenocarcinomas. Ann Surg Oncol. 2014;21(2):621-628.
    • (2014) Ann Surg Oncol , vol.21 , Issue.2 , pp. 621-628
    • Jin, Y.1    Sun, P.L.2    Kim, H.3
  • 109
    • 84890108571 scopus 로고    scopus 로고
    • Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced nonsmall-cell lung cancer
    • Spigel DR, Ervin TJ, Ramlau RA, et al. Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced nonsmall-cell lung cancer. J Clin Oncol. 2013;31(32):4105-4114.
    • (2013) J Clin Oncol , vol.31 , Issue.32 , pp. 4105-4114
    • Spigel, D.R.1    Ervin, T.J.2    Ramlau, R.A.3
  • 110
    • 84915763534 scopus 로고    scopus 로고
    • Increased MET gene copy number but not mRNA level predicts postoperative recurrence in patients with non-small cell lung cancer
    • Kowalczuk O, Kozlowski M, Niklinska W, Kisluk J, Niklinska BJ, Niklinski J. Increased MET gene copy number but not mRNA level predicts postoperative recurrence in patients with non-small cell lung cancer. Transl Oncol. 2014;7(5): 605-612.
    • (2014) Transl Oncol , vol.7 , Issue.5 , pp. 605-612
    • Kowalczuk, O.1    Kozlowski, M.2    Niklinska, W.3    Kisluk, J.4    Niklinska, B.J.5    Niklinski, J.6
  • 111
    • 84922537173 scopus 로고    scopus 로고
    • Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing
    • Jurmeister P, Lenze D, Berg E, et al. Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing. Lung Cancer. 2015;87(2):122-129.
    • (2015) Lung Cancer , vol.87 , Issue.2 , pp. 122-129
    • Jurmeister, P.1    Lenze, D.2    Berg, E.3
  • 112
    • 85019176030 scopus 로고    scopus 로고
    • MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation
    • Noro R, Seike M, Zou F, et al. MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation. BMC Cancer. 2015;15:31. doi:10.1186/s12885-015-1019-1.
    • (2015) BMC Cancer , vol.15 , pp. 31
    • Noro, R.1    Seike, M.2    Zou, F.3
  • 113
    • 84978761759 scopus 로고    scopus 로고
    • Correlation between MET protein expression and MET gene copy number in a Caucasian cohort of nonsmall cell lung cancers according to the new IASLC/ATS/ERS classification
    • Weingertner N, Meyer N, Voegeli AC, et al. Correlation between MET protein expression and MET gene copy number in a Caucasian cohort of nonsmall cell lung cancers according to the new IASLC/ATS/ERS classification. Pathology. 2015;47(4):320-328.
    • (2015) Pathology , vol.47 , Issue.4 , pp. 320-328
    • Weingertner, N.1    Meyer, N.2    Voegeli, A.C.3
  • 114
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007; 316(5827):1039-1043.
    • (2007) Science , vol.316 , Issue.5827 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 115
    • 84942106463 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mutant lung cancer: New drugs, new resistance mechanisms, and future treatment options
    • Piotrowska Z, Sequist LV. Epidermal growth factor receptor-mutant lung cancer: new drugs, new resistance mechanisms, and future treatment options. Cancer J. 2015;21(5):371-377.
    • (2015) Cancer J , vol.21 , Issue.5 , pp. 371-377
    • Piotrowska, Z.1    Sequist, L.V.2
  • 116
    • 85018644112 scopus 로고    scopus 로고
    • Results from the phase III randomized trial of onartuzumab plus erlotinib versus erlotinib in previously treated stage IIIB or IV non-small-cell lung cancer: METLung
    • Spigel DR, Edelman MJ, O'Byrne K, et al. Results from the phase III randomized trial of onartuzumab plus erlotinib versus erlotinib in previously treated stage IIIB or IV non-small-cell lung cancer: METLung. J Clin Oncol. 2017; 35(4):412-420.
    • (2017) J Clin Oncol , vol.35 , Issue.4 , pp. 412-420
    • Spigel, D.R.1    Edelman, M.J.2    O'Byrne, K.3
  • 117
    • 78649420006 scopus 로고    scopus 로고
    • MET signalling: Principles and functions in development, organ regeneration and cancer
    • Trusolino L, Bertotti A, Comoglio PM. MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol. 2010;11(12):834-848.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.12 , pp. 834-848
    • Trusolino, L.1    Bertotti, A.2    Comoglio, P.M.3
  • 119
    • 84997909291 scopus 로고    scopus 로고
    • C-MET as a potential therapeutic target and biomarker in cancer
    • Sierra JR, Tsao MS. c-MET as a potential therapeutic target and biomarker in cancer. Ther Adv Med Oncol. 2011;3(1)(suppl):S21-S35.
    • (2011) Ther Adv Med Oncol , vol.3 , Issue.1 , pp. S21-S35
    • Sierra, J.R.1    Tsao, M.S.2
  • 120
    • 84858341589 scopus 로고    scopus 로고
    • MET signaling: Novel targeted inhibition and its clinical development in lung cancer
    • Feng Y, Thiagarajan PS, Ma PC. MET signaling: novel targeted inhibition and its clinical development in lung cancer. J Thorac Oncol. 2012;7(2):459-467.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 459-467
    • Feng, Y.1    Thiagarajan, P.S.2    Ma, P.C.3
  • 121
    • 33947207989 scopus 로고    scopus 로고
    • Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival
    • Lutterbach B, Zeng Q, Davis LJ, et al. Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. Cancer Res. 2007;67(5):2081-2088.
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 2081-2088
    • Lutterbach, B.1    Zeng, Q.2    Davis, L.J.3
  • 122
    • 84978245406 scopus 로고    scopus 로고
    • Dramatic response to combination erlotinib and crizotinib in a patient with advanced, EGFR-mutant lung cancer harboring de novo MET amplification
    • Gainor JF, Niederst MJ, Lennerz JK, et al. Dramatic response to combination erlotinib and crizotinib in a patient with advanced, EGFR-mutant lung cancer harboring de novo MET amplification. J Thorac Oncol. 2016;11(7): e83-e85.
    • (2016) J Thorac Oncol , vol.11 , Issue.7 , pp. e83-e85
    • Gainor, J.F.1    Niederst, M.J.2    Lennerz, J.K.3
  • 123
    • 0030799090 scopus 로고    scopus 로고
    • Activating mutations for the met tyrosine kinase receptor in human cancer
    • Jeffers M, Schmidt L, Nakaigawa N, et al. Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci U S A. 1997;94(21): 11445-11450.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.21 , pp. 11445-11450
    • Jeffers, M.1    Schmidt, L.2    Nakaigawa, N.3
  • 124
    • 84939204199 scopus 로고    scopus 로고
    • MET receptor juxtamembrane exon 14 alternative spliced variant: Novel cancer genomic predictive biomarker
    • Ma PC. MET receptor juxtamembrane exon 14 alternative spliced variant: novel cancer genomic predictive biomarker. Cancer Discov. 2015;5(8):802-805.
    • (2015) Cancer Discov , vol.5 , Issue.8 , pp. 802-805
    • Ma, P.C.1
  • 125
    • 84961690080 scopus 로고    scopus 로고
    • MET Amplification and exon 14 splice site mutation define unique molecular subgroups of non-small cell lung carcinoma with poor prognosis
    • Tong JH, Yeung SF, Chan AW, et al. MET Amplification and exon 14 splice site mutation define unique molecular subgroups of non-small cell lung carcinoma with poor prognosis. Clin Cancer Res. 2016;22(12):3048-3056.
    • (2016) Clin Cancer Res , vol.22 , Issue.12 , pp. 3048-3056
    • Tong, J.H.1    Yeung, S.F.2    Chan, A.W.3
  • 126
    • 84938815085 scopus 로고    scopus 로고
    • Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
    • Paik PK, Drilon A, Fan PD, et al. Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer Discov. 2015;5(8):842-849.
    • (2015) Cancer Discov , vol.5 , Issue.8 , pp. 842-849
    • Paik, P.K.1    Drilon, A.2    Fan, P.D.3
  • 127
    • 84938805958 scopus 로고    scopus 로고
    • Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
    • Frampton GM, Ali SM, Rosenzweig M, et al. Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. Cancer Discov. 2015;5(8):850-859.
    • (2015) Cancer Discov , vol.5 , Issue.8 , pp. 850-859
    • Frampton, G.M.1    Ali, S.M.2    Rosenzweig, M.3
  • 128
    • 84963865419 scopus 로고    scopus 로고
    • METexon 14 skipping in non-small cell lung cancer
    • Heist RS, Shim HS, Gingipally S, et al. METexon 14 skipping in non-small cell lung cancer. Oncologist. 2016;21(4):481-486.
    • (2016) Oncologist , vol.21 , Issue.4 , pp. 481-486
    • Heist, R.S.1    Shim, H.S.2    Gingipally, S.3
  • 129
    • 84964388926 scopus 로고    scopus 로고
    • MET exon 14 mutations in non-small-cell lung cancer are associated with advanced age and stagedependent MET genomic amplification and c-Met overexpression
    • Awad MM, Oxnard GR, Jackman DM, et al. MET exon 14 mutations in non-small-cell lung cancer are associated with advanced age and stagedependent MET genomic amplification and c-Met overexpression. J Clin Oncol. 2016;34(7):721-730.
    • (2016) J Clin Oncol , vol.34 , Issue.7 , pp. 721-730
    • Awad, M.M.1    Oxnard, G.R.2    Jackman, D.M.3
  • 130
    • 84962609567 scopus 로고    scopus 로고
    • Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations
    • Liu X, Jia Y, Stoopler MB, et al. Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations. J Clin Oncol. 2016;34(8):794-802.
    • (2016) J Clin Oncol , vol.34 , Issue.8 , pp. 794-802
    • Liu, X.1    Jia, Y.2    Stoopler, M.B.3
  • 131
    • 84862777005 scopus 로고    scopus 로고
    • Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer
    • Dziadziuszko R, Wynes MW, Singh S, et al. Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer. J Thorac Oncol. 2012;7(2): 340-347.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 340-347
    • Dziadziuszko, R.1    Wynes, M.W.2    Singh, S.3
  • 132
    • 63849163410 scopus 로고    scopus 로고
    • Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
    • Cappuzzo F, Marchetti A, Skokan M, et al. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. J Clin Oncol. 2009;27(10):1667-1674.
    • (2009) J Clin Oncol , vol.27 , Issue.10 , pp. 1667-1674
    • Cappuzzo, F.1    Marchetti, A.2    Skokan, M.3
  • 133
    • 84982094993 scopus 로고    scopus 로고
    • Identifying the appropriate FISH criteria for defining MET copy number-driven lung adenocarcinoma through oncogene overlap analysis
    • Noonan SA, Berry L, Lu X, et al. Identifying the appropriate FISH criteria for defining MET copy number-driven lung adenocarcinoma through oncogene overlap analysis. J Thorac Oncol. 2016;11(8):1293-1304.
    • (2016) J Thorac Oncol , vol.11 , Issue.8 , pp. 1293-1304
    • Noonan, S.A.1    Berry, L.2    Lu, X.3
  • 134
    • 79955458487 scopus 로고    scopus 로고
    • Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification
    • Ou SH, Kwak EL, Siwak-Tapp C, et al. Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol. 2011;6(5):942-946.
    • (2011) J Thorac Oncol , vol.6 , Issue.5 , pp. 942-946
    • Ou, S.H.1    Kwak, E.L.2    Siwak-Tapp, C.3
  • 135
    • 85015268534 scopus 로고    scopus 로고
    • Responses to crizotinib can occur in high-level MET-amplified non-small cell lung cancer independent of MET exon 14 alterations
    • Caparica R, Yen CT, Coudry R, et al. Responses to crizotinib can occur in high-level MET-amplified non-small cell lung cancer independent of MET exon 14 alterations. J Thorac Oncol. 2017;12(1):141-144.
    • (2017) J Thorac Oncol , vol.12 , Issue.1 , pp. 141-144
    • Caparica, R.1    Yen, C.T.2    Coudry, R.3
  • 136
    • 84907561441 scopus 로고    scopus 로고
    • Safety and efficacy of INC280 in combination with gefitinib (gef) in patients with EGFR-mutated (mut), METpositive NSCLC: A single-arm phase Ib/II study
    • Wu Y-L, Yang JC-H, Kim D-W, et al. Safety and efficacy of INC280 in combination with gefitinib (gef) in patients with EGFR-mutated (mut), METpositive NSCLC: a single-arm phase Ib/II study. J Clin Oncol. 2014;32(5s):8017.
    • (2014) J Clin Oncol , vol.32 , Issue.5 S , pp. 8017
    • Wu, Y.-L.1    Yang, J.C.-H.2    Kim, D.-W.3
  • 137
    • 84858335323 scopus 로고    scopus 로고
    • C-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas
    • Tsuta K, Kozu Y, Mimae T, et al. c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas. J Thorac Oncol. 2012;7(2):331-339.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 331-339
    • Tsuta, K.1    Kozu, Y.2    Mimae, T.3
  • 138
    • 84905011727 scopus 로고    scopus 로고
    • Biomarker analyses from a placebocontrolled phase II study evaluating erlotinib 6 onartuzumab in advanced nonsmall cell lung cancer: MET expression levels are predictive of patient benefit
    • Koeppen H, Yu W, Zha J, et al. Biomarker analyses from a placebocontrolled phase II study evaluating erlotinib 6 onartuzumab in advanced nonsmall cell lung cancer: MET expression levels are predictive of patient benefit. Clin Cancer Res. 2014;20(17):4488-4498.
    • (2014) Clin Cancer Res , vol.20 , Issue.17 , pp. 4488-4498
    • Koeppen, H.1    Yu, W.2    Zha, J.3
  • 139
    • 84857781304 scopus 로고    scopus 로고
    • Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: A French study
    • McLeer-Florin A, Moro-Sibilot D, Melis A, et al. Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study. J Thorac Oncol. 2012;7(2):348-354.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 348-354
    • McLeer-Florin, A.1    Moro-Sibilot, D.2    Melis, A.3
  • 140
    • 84874023763 scopus 로고    scopus 로고
    • Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas
    • Sholl LM, Weremowicz S, Gray SW, et al. Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas. J Thorac Oncol. 2013;8(3):322-328.
    • (2013) J Thorac Oncol , vol.8 , Issue.3 , pp. 322-328
    • Sholl, L.M.1    Weremowicz, S.2    Gray, S.W.3
  • 141
    • 84863784502 scopus 로고    scopus 로고
    • Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients
    • Park HS, Lee JK, Kim DW, et al. Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients. Lung Cancer. 2012;77(2):288-292.
    • (2012) Lung Cancer , vol.77 , Issue.2 , pp. 288-292
    • Park, H.S.1    Lee, J.K.2    Kim, D.W.3
  • 142
    • 84876482049 scopus 로고    scopus 로고
    • ALK status testing in non-small cell lung carcinoma: Correlation between ultrasensitive IHC and FISH
    • Minca EC, Portier BP, Wang Z, et al. ALK status testing in non-small cell lung carcinoma: correlation between ultrasensitive IHC and FISH. J Mol Diagn. 2013;15(3):341-346.
    • (2013) J Mol Diagn , vol.15 , Issue.3 , pp. 341-346
    • Minca, E.C.1    Portier, B.P.2    Wang, Z.3
  • 143
    • 84880917013 scopus 로고    scopus 로고
    • Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant
    • To KF, Tong JH, Yeung KS, et al. Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant. J Thorac Oncol. 2013;8(7):883-891.
    • (2013) J Thorac Oncol , vol.8 , Issue.7 , pp. 883-891
    • To, K.F.1    Tong, J.H.2    Yeung, K.S.3
  • 144
    • 84906812668 scopus 로고    scopus 로고
    • Prevalence and clinical outcomes for patients with ALK-positive resected stage i to III adenocarcinoma: Results from the European Thoracic Oncology Platform Lungscape Project
    • Blackhall FH, Peters S, Bubendorf L, et al. Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project. J Clin Oncol. 2014;32(25):2780-2787.
    • (2014) J Clin Oncol , vol.32 , Issue.25 , pp. 2780-2787
    • Blackhall, F.H.1    Peters, S.2    Bubendorf, L.3
  • 145
    • 84907584497 scopus 로고    scopus 로고
    • Accurate identification of ALK positive lung carcinoma patients: Novel FDA-cleared automated fluorescence in situ hybridization scanning system and ultrasensitive immunohistochemistry
    • Conde E, Suarez-Gauthier A, Benito A, et al. Accurate identification of ALK positive lung carcinoma patients: novel FDA-cleared automated fluorescence in situ hybridization scanning system and ultrasensitive immunohistochemistry. PLoS One. 2014;9(9):e107200. doi:10.1371/journal.pone.0107200.
    • (2014) PLoS One , vol.9 , Issue.9 , pp. e107200
    • Conde, E.1    Suarez-Gauthier, A.2    Benito, A.3
  • 146
    • 84906258686 scopus 로고    scopus 로고
    • Canadian anaplastic lymphoma kinase study: A model for multicenter standardization and optimization of ALK testing in lung cancer
    • Cutz JC, Craddock KJ, Torlakovic E, et al. Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. J Thorac Oncol. 2014;9(9):1255-1263.
    • (2014) J Thorac Oncol , vol.9 , Issue.9 , pp. 1255-1263
    • Cutz, J.C.1    Craddock, K.J.2    Torlakovic, E.3
  • 147
    • 84900847210 scopus 로고    scopus 로고
    • Retrospective study of ALK rearrangement and clinicopathological implications in completely resected non-small cell lung cancer patients in northern Thailand: Role of screening with D5F3 antibodies
    • Tantraworasin A, Lertprasertsuke N, Kongkarnka S, Euathrongchit J, Wannasopha Y, Saeteng S. Retrospective study of ALK rearrangement and clinicopathological implications in completely resected non-small cell lung cancer patients in northern Thailand: role of screening with D5F3 antibodies. Asian Pac J Cancer Prev. 2014;15(7):3057-3063.
    • (2014) Asian Pac J Cancer Prev , vol.15 , Issue.7 , pp. 3057-3063
    • Tantraworasin, A.1    Lertprasertsuke, N.2    Kongkarnka, S.3    Euathrongchit, J.4    Wannasopha, Y.5    Saeteng, S.6
  • 148
    • 84903777245 scopus 로고    scopus 로고
    • Clinical characteristics and outcomes of patients with primary lung adenocarcinoma harboring ALK rearrangements detected by FISH IHC and RT-PCR
    • Wang J, Cai Y, Dong Y, et al. Clinical characteristics and outcomes of patients with primary lung adenocarcinoma harboring ALK rearrangements detected by FISH, IHC, and RT-PCR. PLoS One. 2014;9(7):e101551. doi:10.1371/journal.pone.0101551.
    • (2014) PLoS One , vol.9 , Issue.7 , pp. e101551
    • Wang, J.1    Cai, Y.2    Dong, Y.3
  • 149
    • 84655170204 scopus 로고    scopus 로고
    • Worse disease-free survival in neversmokers with ALK+ lung adenocarcinoma
    • Yang P, Kulig K, Boland JM, et al. Worse disease-free survival in neversmokers with ALK+ lung adenocarcinoma. J Thorac Oncol. 2012;7(1):90-97.
    • (2012) J Thorac Oncol , vol.7 , Issue.1 , pp. 90-97
    • Yang, P.1    Kulig, K.2    Boland, J.M.3
  • 150
    • 84884730006 scopus 로고    scopus 로고
    • Diagnostic value of a novel fully automated immunochemistry assay for detection of ALK rearrangement in primary lung adenocarcinoma
    • Ying J, Guo L, Qiu T, et al. Diagnostic value of a novel fully automated immunochemistry assay for detection of ALK rearrangement in primary lung adenocarcinoma. Ann Oncol. 2013;24(10):2589-2593.
    • (2013) Ann Oncol , vol.24 , Issue.10 , pp. 2589-2593
    • Ying, J.1    Guo, L.2    Qiu, T.3
  • 151
    • 84892376227 scopus 로고    scopus 로고
    • Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement
    • Shan L, Lian F, Guo L, Yang X, Ying J, Lin D. Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement. Diagn Pathol. 2014;9:3. doi:10.1186/1746-1596-9-3.
    • (2014) Diagn Pathol , vol.9 , pp. 3
    • Shan, L.1    Lian, F.2    Guo, L.3    Yang, X.4    Ying, J.5    Lin, D.6
  • 152
    • 84911805945 scopus 로고    scopus 로고
    • Detection of ALK expression in non-small-cell lung cancer with ALK gene rearrangements- comparison of multiple immunohistochemical methods
    • Zwaenepoel K, Van Dongen A, Lambin S, Weyn C, Pauwels P. Detection of ALK expression in non-small-cell lung cancer with ALK gene rearrangements- comparison of multiple immunohistochemical methods. Histopathology. 2014; 65(4):539-548.
    • (2014) Histopathology , vol.65 , Issue.4 , pp. 539-548
    • Zwaenepoel, K.1    Van Dongen, A.2    Lambin, S.3    Weyn, C.4    Pauwels, P.5
  • 153
    • 84938275479 scopus 로고    scopus 로고
    • A novel, highly sensitive ALK antibody 1A4 facilitates effective screening for ALK rearrangements in lung adenocarcinomas by standard immunohistochemistry
    • Gruber K, Kohlhaufl M, Friedel G, Ott G, Kalla C. A novel, highly sensitive ALK antibody 1A4 facilitates effective screening for ALK rearrangements in lung adenocarcinomas by standard immunohistochemistry. J Thorac Oncol. 2015; 10(4):713-716.
    • (2015) J Thorac Oncol , vol.10 , Issue.4 , pp. 713-716
    • Gruber, K.1    Kohlhaufl, M.2    Friedel, G.3    Ott, G.4    Kalla, C.5
  • 154
    • 84937436081 scopus 로고    scopus 로고
    • French multicentric validation of ALK rearrangement diagnostic in 547 lung adenocarcinomas
    • Lantuejoul S, Rouquette I, Blons H, et al. French multicentric validation of ALK rearrangement diagnostic in 547 lung adenocarcinomas. Eur Respir J. 2015; 46(1):201-218.
    • (2015) Eur Respir J , vol.46 , Issue.1 , pp. 201-218
    • Lantuejoul, S.1    Rouquette, I.2    Blons, H.3
  • 155
    • 84937643839 scopus 로고    scopus 로고
    • Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended
    • Savic S, Diebold J, Zimmermann AK, et al. Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended. Lung Cancer. 2015;89(2):104-109.
    • (2015) Lung Cancer , vol.89 , Issue.2 , pp. 104-109
    • Savic, S.1    Diebold, J.2    Zimmermann, A.K.3
  • 156
    • 84922691277 scopus 로고    scopus 로고
    • ALK rearrangement in a large series of consecutive non-small cell lung cancers: Comparison between a new immunohistochemical approach and fluorescence in situ hybridization for the screening of patients eligible for crizotinib treatment
    • Ali G, Proietti A, Pelliccioni S, et al. ALK rearrangement in a large series of consecutive non-small cell lung cancers: comparison between a new immunohistochemical approach and fluorescence in situ hybridization for the screening of patients eligible for crizotinib treatment. Arch Pathol Lab Med. 2014;138(11): 1449-1458.
    • (2014) Arch Pathol Lab Med , vol.138 , Issue.11 , pp. 1449-1458
    • Ali, G.1    Proietti, A.2    Pelliccioni, S.3
  • 157
    • 84920523851 scopus 로고    scopus 로고
    • Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: Evaluation of five different ALK antibody clones and ALK FISH
    • Hutarew G, Hauser-Kronberger C, Strasser F, Llenos IC, Dietze O. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. Histopathology. 2014;65(3):398-407.
    • (2014) Histopathology , vol.65 , Issue.3 , pp. 398-407
    • Hutarew, G.1    Hauser-Kronberger, C.2    Strasser, F.3    Llenos, I.C.4    Dietze, O.5
  • 158
    • 77649091118 scopus 로고    scopus 로고
    • A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
    • Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res. 2010;16(5):1561-1571.
    • (2010) Clin Cancer Res , vol.16 , Issue.5 , pp. 1561-1571
    • Mino-Kenudson, M.1    Chirieac, L.R.2    Law, K.3
  • 159
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res. 2009;15(16):5216-5223.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3
  • 160
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol. 2009;27(26):4247-4253.
    • (2009) J Clin Oncol , vol.27 , Issue.26 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3
  • 161
    • 80051784751 scopus 로고    scopus 로고
    • Detection of ALK gene rearrangement in non-small cell lung cancer: A comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression
    • Kim H, Yoo SB, Choe JY, et al. Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression. J Thorac Oncol. 2011;6(8):1359-1366.
    • (2011) J Thorac Oncol , vol.6 , Issue.8 , pp. 1359-1366
    • Kim, H.1    Yoo, S.B.2    Choe, J.Y.3
  • 162
    • 84962881211 scopus 로고    scopus 로고
    • ALK protein analysis by IHC staining after recent regulatory changes: A comparison of two widely used approaches, revision of the literature, and a new testing algorithm
    • Marchetti A, Di Lorito A, Pace MV, et al. ALK protein analysis by IHC staining after recent regulatory changes: a comparison of two widely used approaches, revision of the literature, and a new testing algorithm. J Thorac Oncol. 2016;11(4):487-495.
    • (2016) J Thorac Oncol , vol.11 , Issue.4 , pp. 487-495
    • Marchetti, A.1    Di Lorito, A.2    Pace, M.V.3
  • 163
    • 84925411861 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer
    • Pekar-Zlotin M, Hirsch FR, Soussan-Gutman L, et al. Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer. Oncologist. 2015;20(3): 316-322.
    • (2015) Oncologist , vol.20 , Issue.3 , pp. 316-322
    • Pekar-Zlotin, M.1    Hirsch, F.R.2    Soussan-Gutman, L.3
  • 165
    • 85003874972 scopus 로고    scopus 로고
    • ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma
    • Dacic S, Villaruz LC, Abberbock S, Mahaffey A, Incharoen P, Nikiforova MN. ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma. Oncotarget. 2016;7(50):82943-82952.
    • (2016) Oncotarget , vol.7 , Issue.50 , pp. 82943-82952
    • Dacic, S.1    Villaruz, L.C.2    Abberbock, S.3    Mahaffey, A.4    Incharoen, P.5    Nikiforova, M.N.6
  • 166
    • 84894514080 scopus 로고    scopus 로고
    • Parallel FISH and immunohistochemical studies of ALK status in 3244 non-small-cell lung cancers reveal major discordances
    • Cabillic F, Gros A, Dugay F, et al. Parallel FISH and immunohistochemical studies of ALK status in 3244 non-small-cell lung cancers reveal major discordances. J Thorac Oncol. 2014;9(3):295-306.
    • (2014) J Thorac Oncol , vol.9 , Issue.3 , pp. 295-306
    • Cabillic, F.1    Gros, A.2    Dugay, F.3
  • 167
    • 84979774603 scopus 로고    scopus 로고
    • Reliability assurance of detection of EML4-ALK rearrangement in non-small cell lung cancer: The results of proficiency testing in China
    • Li Y, Zhang R, Peng R, et al. Reliability assurance of detection of EML4-ALK rearrangement in non-small cell lung cancer: the results of proficiency testing in China. J Thorac Oncol. 2016;11(6):924-929.
    • (2016) J Thorac Oncol , vol.11 , Issue.6 , pp. 924-929
    • Li, Y.1    Zhang, R.2    Peng, R.3
  • 168
    • 84867557923 scopus 로고    scopus 로고
    • A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer
    • Soda M, Isobe K, Inoue A, et al. A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer. Clin Cancer Res. 2012; 18(20):5682-5689.
    • (2012) Clin Cancer Res , vol.18 , Issue.20 , pp. 5682-5689
    • Soda, M.1    Isobe, K.2    Inoue, A.3
  • 169
    • 84942521554 scopus 로고    scopus 로고
    • Broad, hybrid capture-based nextgeneration sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches
    • Drilon A, Wang L, Arcila ME, et al. Broad, hybrid capture-based nextgeneration sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches. Clin Cancer Res. 2015;21(16):3631-3639.
    • (2015) Clin Cancer Res , vol.21 , Issue.16 , pp. 3631-3639
    • Drilon, A.1    Wang, L.2    Arcila, M.E.3
  • 170
    • 84903881552 scopus 로고    scopus 로고
    • Detecting the spectrum of multigene mutations in non-small cell lung cancer by Snapshot assay
    • Su J, Zhang XC, An SJ, et al. Detecting the spectrum of multigene mutations in non-small cell lung cancer by Snapshot assay. Chin J Cancer. 2014; 33(7):346-350.
    • (2014) Chin J Cancer , vol.33 , Issue.7 , pp. 346-350
    • Su, J.1    Zhang, X.C.2    An, S.J.3
  • 171
    • 84904122641 scopus 로고    scopus 로고
    • Comparison of targeted next-generation sequencing with conventional sequencing for predicting the responsiveness to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy in never-smokers with lung adenocarcinoma
    • Han JY, Kim SH, Lee YS, et al. Comparison of targeted next-generation sequencing with conventional sequencing for predicting the responsiveness to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy in never-smokers with lung adenocarcinoma. Lung Cancer. 2014;85(2):161-167.
    • (2014) Lung Cancer , vol.85 , Issue.2 , pp. 161-167
    • Han, J.Y.1    Kim, S.H.2    Lee, Y.S.3
  • 172
    • 84875077830 scopus 로고    scopus 로고
    • Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS
    • Tuononen K, Maki-Nevala S, Sarhadi VK, et al. Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS. Genes Chromosomes Cancer. 2013;52(5):503-511.
    • (2013) Genes Chromosomes Cancer , vol.52 , Issue.5 , pp. 503-511
    • Tuononen, K.1    Maki-Nevala, S.2    Sarhadi, V.K.3
  • 173
    • 84893411121 scopus 로고    scopus 로고
    • Molecular typing of lung adenocarcinoma on cytological samples using a multigene next generation sequencing panel
    • Scarpa A, Sikora K, Fassan M, et al. Molecular typing of lung adenocarcinoma on cytological samples using a multigene next generation sequencing panel. PLoS One. 2013;8(11):e80478. doi:10.1371/journal.pone. 0080478.
    • (2013) PLoS One , vol.8 , Issue.11 , pp. e80478
    • Scarpa, A.1    Sikora, K.2    Fassan, M.3
  • 174
    • 85018464523 scopus 로고    scopus 로고
    • Guidelines for validation of nextgeneration sequencing-based oncology panels: A joint consensus recommendation of the Association for Molecular Pathology and College of American Pathologists
    • Jennings LJ, Arcila ME, Corless C, et al. Guidelines for validation of nextgeneration sequencing-based oncology panels: a joint consensus recommendation of the Association for Molecular Pathology and College of American Pathologists. J Mol Diagn. 2017;19(3):341-365.
    • (2017) J Mol Diagn , vol.19 , Issue.3 , pp. 341-365
    • Jennings, L.J.1    Arcila, M.E.2    Corless, C.3
  • 175
    • 84886052163 scopus 로고    scopus 로고
    • Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: Feasibility, costs, and performance compared with conventional sequencing
    • Endris V, Penzel R, Warth A, et al. Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing. J Mol Diagn. 2013;15(6):765-775.
    • (2013) J Mol Diagn , vol.15 , Issue.6 , pp. 765-775
    • Endris, V.1    Penzel, R.2    Warth, A.3
  • 176
    • 84893522267 scopus 로고    scopus 로고
    • Library construction for nextgeneration sequencing: Overviews and challenges
    • Head SR, Komori HK, LaMere SA, et al. Library construction for nextgeneration sequencing: overviews and challenges. Biotechniques. 2014;56(2): 61-77.
    • (2014) Biotechniques , vol.56 , Issue.2 , pp. 61-77
    • Head, S.R.1    Komori, H.K.2    LaMere, S.A.3
  • 177
    • 84857087591 scopus 로고    scopus 로고
    • Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: Lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
    • Rekhtman N, Paik PK, Arcila ME, et al. Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations. Clin Cancer Res. 2012; 18(4):1167-1176.
    • (2012) Clin Cancer Res , vol.18 , Issue.4 , pp. 1167-1176
    • Rekhtman, N.1    Paik, P.K.2    Arcila, M.E.3
  • 178
    • 79953024710 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase catalytic alpha and KRAS mutations are important predictors of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer
    • Ludovini V, Bianconi F, Pistola L, et al. Phosphoinositide-3-kinase catalytic alpha and KRAS mutations are important predictors of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer. J Thorac Oncol. 2011;6(4):707-715.
    • (2011) J Thorac Oncol , vol.6 , Issue.4 , pp. 707-715
    • Ludovini, V.1    Bianconi, F.2    Pistola, L.3
  • 179
    • 34047132314 scopus 로고    scopus 로고
    • Combination of EGFR gene copy number and protein expression predicts outcome for advanced nonsmall-cell lung cancer patients treated with gefitinib
    • Hirsch FR, Varella-Garcia M, Cappuzzo F, et al. Combination of EGFR gene copy number and protein expression predicts outcome for advanced nonsmall-cell lung cancer patients treated with gefitinib. Ann Oncol. 2007;18(4): 752-760.
    • (2007) Ann Oncol , vol.18 , Issue.4 , pp. 752-760
    • Hirsch, F.R.1    Varella-Garcia, M.2    Cappuzzo, F.3
  • 180
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
    • Massarelli E, Varella-Garcia M, Tang X, et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res. 2007;13(10):2890-2896.
    • (2007) Clin Cancer Res , vol.13 , Issue.10 , pp. 2890-2896
    • Massarelli, E.1    Varella-Garcia, M.2    Tang, X.3
  • 181
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol. 2009;22(4):508-515.
    • (2009) Mod Pathol , vol.22 , Issue.4 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 182
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12(11):1004-1012.
    • (2011) Lancet Oncol , vol.12 , Issue.11 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 183
    • 84863010944 scopus 로고    scopus 로고
    • Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma
    • Girard N, Sima CS, Jackman DM, et al. Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma. Eur Respir J. 2012;39(2): 366-372.
    • (2012) Eur Respir J , vol.39 , Issue.2 , pp. 366-372
    • Girard, N.1    Sima, C.S.2    Jackman, D.M.3
  • 184
    • 84869224992 scopus 로고    scopus 로고
    • Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: Higher susceptibility of women to smoking-related KRAS-mutant cancers
    • Dogan S, Shen R, Ang DC, et al. Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers. Clin Cancer Res. 2012;18(22):6169-6177.
    • (2012) Clin Cancer Res , vol.18 , Issue.22 , pp. 6169-6177
    • Dogan, S.1    Shen, R.2    Ang, D.C.3
  • 185
    • 58149385365 scopus 로고    scopus 로고
    • Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications
    • Wu CC, Hsu HY, Liu HP, et al. Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. Cancer. 2008;113(11):3199-3208.
    • (2008) Cancer , vol.113 , Issue.11 , pp. 3199-3208
    • Wu, C.C.1    Hsu, H.Y.2    Liu, H.P.3
  • 186
    • 40049100818 scopus 로고    scopus 로고
    • Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma
    • Marks JL, Broderick S, Zhou Q, et al. Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma. J Thorac Oncol. 2008;3(2):111-116.
    • (2008) J Thorac Oncol , vol.3 , Issue.2 , pp. 111-116
    • Marks, J.L.1    Broderick, S.2    Zhou, Q.3
  • 187
    • 58949089105 scopus 로고    scopus 로고
    • A sensitive method for detecting EGFR mutations in non-small cell lung cancer samples with few tumor cells
    • Molina-Vila MA, Bertran-Alamillo J, Reguart N, et al. A sensitive method for detecting EGFR mutations in non-small cell lung cancer samples with few tumor cells. J Thorac Oncol. 2008;3(11):1224-1235.
    • (2008) J Thorac Oncol , vol.3 , Issue.11 , pp. 1224-1235
    • Molina-Vila, M.A.1    Bertran-Alamillo, J.2    Reguart, N.3
  • 188
    • 58949091382 scopus 로고    scopus 로고
    • An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients
    • Kawada I, Soejima K, Watanabe H, et al. An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients. J Thorac Oncol. 2008;3(10):1096-1103.
    • (2008) J Thorac Oncol , vol.3 , Issue.10 , pp. 1096-1103
    • Kawada, I.1    Soejima, K.2    Watanabe, H.3
  • 189
    • 70349758654 scopus 로고    scopus 로고
    • Activating mutations within the EGFR kinase domain: A molecular predictor of disease-free survival in resected pulmonary adenocarcinoma
    • Lee YJ, Park IK, Park MS, et al. Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma. J Cancer Res Clin Oncol. 2009;135(12):1647-1654.
    • (2009) J Cancer Res Clin Oncol , vol.135 , Issue.12 , pp. 1647-1654
    • Lee, Y.J.1    Park, I.K.2    Park, M.S.3
  • 190
    • 34547098367 scopus 로고    scopus 로고
    • Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer
    • Soh J, Toyooka S, Ichihara S, et al. Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer. Int J Cancer. 2007; 121(5):1162-1167.
    • (2007) Int J Cancer , vol.121 , Issue.5 , pp. 1162-1167
    • Soh, J.1    Toyooka, S.2    Ichihara, S.3
  • 191
    • 77957358324 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations detected by denaturing high-performance liquid chromatography in nonsmall cell lung cancer: Impact on response to therapy with epidermal growth factor receptor-tyrosine kinase inhibitors
    • Cohen V, Agulnik JS, Ang C, et al. Epidermal growth factor receptor mutations detected by denaturing high-performance liquid chromatography in nonsmall cell lung cancer: impact on response to therapy with epidermal growth factor receptor-tyrosine kinase inhibitors. Cancer. 2010;116(18):4309-4317.
    • (2010) Cancer , vol.116 , Issue.18 , pp. 4309-4317
    • Cohen, V.1    Agulnik, J.S.2    Ang, C.3
  • 192
    • 79954574430 scopus 로고    scopus 로고
    • Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry
    • Harada T, Lopez-Chavez A, Xi L, Raffeld M, Wang Y, Giaccone G. Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry. Oncogene. 2011;30(15): 1744-1752.
    • (2011) Oncogene , vol.30 , Issue.15 , pp. 1744-1752
    • Harada, T.1    Lopez-Chavez, A.2    Xi, L.3    Raffeld, M.4    Wang, Y.5    Giaccone, G.6
  • 193
    • 34547492416 scopus 로고    scopus 로고
    • Clinical significance of epidermal growth factor receptor gene mutations on treatment outcome after first-line cytotoxic chemotherapy in Japanese patients with non-small cell lung cancer
    • Hotta K, Kiura K, Toyooka S, et al. Clinical significance of epidermal growth factor receptor gene mutations on treatment outcome after first-line cytotoxic chemotherapy in Japanese patients with non-small cell lung cancer. J Thorac Oncol. 2007;2(7):632-637.
    • (2007) J Thorac Oncol , vol.2 , Issue.7 , pp. 632-637
    • Hotta, K.1    Kiura, K.2    Toyooka, S.3
  • 194
    • 33644545057 scopus 로고    scopus 로고
    • Mutations of epidermal growth factor receptor of non-small cell lung cancer were associated with sensitivity to gefitinib in recurrence after surgery
    • Kondo M, Yokoyama T, Fukui T, et al. Mutations of epidermal growth factor receptor of non-small cell lung cancer were associated with sensitivity to gefitinib in recurrence after surgery. Lung Cancer. 2005;50(3):385-391.
    • (2005) Lung Cancer , vol.50 , Issue.3 , pp. 385-391
    • Kondo, M.1    Yokoyama, T.2    Fukui, T.3
  • 195
    • 79952268212 scopus 로고    scopus 로고
    • Brain metastases from lung cancer responding to erlotinib: The importance of EGFR mutation
    • Porta R, Sanchez-Torres JM, Paz-Ares L, et al. Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation. Eur Respir J. 2011;37(3):624-631.
    • (2011) Eur Respir J , vol.37 , Issue.3 , pp. 624-631
    • Porta, R.1    Sanchez-Torres, J.M.2    Paz-Ares, L.3
  • 196
    • 41049086345 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer
    • Sasaki H, Endo K, Okuda K, et al. Epidermal growth factor receptor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer. J Cancer Res Clin Oncol. 2008;134(5):569-577.
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.5 , pp. 569-577
    • Sasaki, H.1    Endo, K.2    Okuda, K.3
  • 197
    • 34247212825 scopus 로고    scopus 로고
    • Predictive factors associated with prolonged survival in patients with advanced non-small-cell lung cancer (NSCLC) treated with gefitinib
    • Satouchi M, Negoro S, Funada Y, et al. Predictive factors associated with prolonged survival in patients with advanced non-small-cell lung cancer (NSCLC) treated with gefitinib. Br J Cancer. 2007;96(8):1191-1196.
    • (2007) Br J Cancer , vol.96 , Issue.8 , pp. 1191-1196
    • Satouchi, M.1    Negoro, S.2    Funada, Y.3
  • 198
    • 23844490782 scopus 로고    scopus 로고
    • Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas
    • Taron M, Ichinose Y, Rosell R, et al. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res. 2005;11(16):5878-5885.
    • (2005) Clin Cancer Res , vol.11 , Issue.16 , pp. 5878-5885
    • Taron, M.1    Ichinose, Y.2    Rosell, R.3
  • 199
    • 30644458252 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations are associated with gefitinib sensitivity in non-small cell lung cancer in Japanese
    • Uramoto H, Sugio K, Oyama T, et al. Epidermal growth factor receptor mutations are associated with gefitinib sensitivity in non-small cell lung cancer in Japanese. Lung Cancer. 2006;51(1):71-77.
    • (2006) Lung Cancer , vol.51 , Issue.1 , pp. 71-77
    • Uramoto, H.1    Sugio, K.2    Oyama, T.3
  • 200
    • 43949125179 scopus 로고    scopus 로고
    • EGFR/KRAS mutations and gefitinib therapy in Chinese NSCLC patients
    • Wang Z, Wu YL, Zhang GC, Zhou Q, Xu CR, Guo AL. EGFR/KRAS mutations and gefitinib therapy in Chinese NSCLC patients. Onkologie. 2008; 31(4):174-178.
    • (2008) Onkologie , vol.31 , Issue.4 , pp. 174-178
    • Wang, Z.1    Wu, Y.L.2    Zhang, G.C.3    Zhou, Q.4    Xu, C.R.5    Guo, A.L.6
  • 201
    • 67349205024 scopus 로고    scopus 로고
    • EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib
    • Xu JM, Han Y, Duan HQ, et al. EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib. J Cancer Res Clin Oncol. 2009;135(6):771-782.
    • (2009) J Cancer Res Clin Oncol , vol.135 , Issue.6 , pp. 771-782
    • Xu, J.M.1    Han, Y.2    Duan, H.Q.3
  • 202
    • 79955598867 scopus 로고    scopus 로고
    • Gefitinib therapy in patients with advanced non-small cell lung cancer with or without testing for epidermal growth factor receptor (EGFR) mutations
    • Wu JY, Shih JY, Chen KY, Yang CH, Yu CJ, Yang PC. Gefitinib therapy in patients with advanced non-small cell lung cancer with or without testing for epidermal growth factor receptor (EGFR) mutations. Medicine (Baltimore). 2011; 90(3):159-167.
    • (2011) Medicine (Baltimore) , vol.90 , Issue.3 , pp. 159-167
    • Wu, J.Y.1    Shih, J.Y.2    Chen, K.Y.3    Yang, C.H.4    Yu, C.J.5    Yang, P.C.6
  • 203
    • 33750205340 scopus 로고    scopus 로고
    • A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
    • Asahina H, Yamazaki K, Kinoshita I, et al. A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer. 2006;95(8):998-1004.
    • (2006) Br J Cancer , vol.95 , Issue.8 , pp. 998-1004
    • Asahina, H.1    Yamazaki, K.2    Kinoshita, I.3
  • 204
    • 33847091172 scopus 로고    scopus 로고
    • EGFR ERBB2 and KRAS mutations in Korean non-small cell lung cancer patients
    • Bae NC, Chae MH, Lee MH, et al. EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients. Cancer Genet Cytogenet. 2007; 173(2):107-113.
    • (2007) Cancer Genet Cytogenet , vol.173 , Issue.2 , pp. 107-113
    • Bae, N.C.1    Chae, M.H.2    Lee, M.H.3
  • 205
    • 33645163460 scopus 로고    scopus 로고
    • A correlation between EGFR gene mutation status and bronchioloalveolar carcinoma features in Japanese patients with adenocarcinoma
    • Haneda H, Sasaki H, Lindeman N, et al. A correlation between EGFR gene mutation status and bronchioloalveolar carcinoma features in Japanese patients with adenocarcinoma. Jpn J Clin Oncol. 2006;36(2):69-75.
    • (2006) Jpn J Clin Oncol , vol.36 , Issue.2 , pp. 69-75
    • Haneda, H.1    Sasaki, H.2    Lindeman, N.3
  • 206
    • 32944481596 scopus 로고    scopus 로고
    • Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
    • Riely GJ, Pao W, Pham D, et al. Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib. Clin Cancer Res. 2006;12(3 Pt 1): 839-844.
    • (2006) Clin Cancer Res , vol.12 , pp. 839-844
    • Riely, G.J.1    Pao, W.2    Pham, D.3
  • 207
    • 67349144683 scopus 로고    scopus 로고
    • Prospective phase II study of gefitinib in non-small cell lung cancer with epidermal growth factor receptor gene mutations
    • Sugio K, Uramoto H, Onitsuka T, et al. Prospective phase II study of gefitinib in non-small cell lung cancer with epidermal growth factor receptor gene mutations. Lung Cancer. 2009;64(3):314-318.
    • (2009) Lung Cancer , vol.64 , Issue.3 , pp. 314-318
    • Sugio, K.1    Uramoto, H.2    Onitsuka, T.3
  • 208
    • 34247619676 scopus 로고    scopus 로고
    • Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy
    • Sunaga N, Tomizawa Y, Yanagitani N, et al. Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy. Lung Cancer. 2007; 56(3):383-389.
    • (2007) Lung Cancer , vol.56 , Issue.3 , pp. 383-389
    • Sunaga, N.1    Tomizawa, Y.2    Yanagitani, N.3
  • 209
    • 61449259809 scopus 로고    scopus 로고
    • Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas
    • Tang X, Varella-Garcia M, Xavier AC, et al. Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas. Cancer Prev Res (Phila). 2008;1(3):192-200.
    • (2008) Cancer Prev Res (Phila) , vol.1 , Issue.3 , pp. 192-200
    • Tang, X.1    Varella-Garcia, M.2    Xavier, A.C.3
  • 210
    • 79951761631 scopus 로고    scopus 로고
    • Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer
    • Cote ML, Haddad R, Edwards DJ, et al. Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer. J Thorac Oncol. 2011;6(3):627-630.
    • (2011) J Thorac Oncol , vol.6 , Issue.3 , pp. 627-630
    • Cote, M.L.1    Haddad, R.2    Edwards, D.J.3
  • 211
    • 77953158526 scopus 로고    scopus 로고
    • High efficacy of firstline gefitinib in non-Asian patients with EGFR-mutated lung adenocarcinoma
    • Moiseyenko VM, Procenko SA, Levchenko EV, et al. High efficacy of firstline gefitinib in non-Asian patients with EGFR-mutated lung adenocarcinoma. Onkologie. 2010;33(5):231-238.
    • (2010) Onkologie , vol.33 , Issue.5 , pp. 231-238
    • Moiseyenko, V.M.1    Procenko, S.A.2    Levchenko, E.V.3
  • 212
    • 79960860845 scopus 로고    scopus 로고
    • Screening for EGFR mutations in lung cancer, a report from India
    • Sahoo R, Harini VV, Babu VC, et al. Screening for EGFR mutations in lung cancer, a report from India. Lung Cancer. 2011;73(3):316-319.
    • (2011) Lung Cancer , vol.73 , Issue.3 , pp. 316-319
    • Sahoo, R.1    Harini, V.V.2    Babu, V.C.3
  • 213
    • 43049112800 scopus 로고    scopus 로고
    • Detection of EGFR gene mutations using the wash fluid of CT-guided biopsy needle in NSCLC patients
    • Otani H, Toyooka S, Soh J, et al. Detection of EGFR gene mutations using the wash fluid of CT-guided biopsy needle in NSCLC patients. J Thorac Oncol. 2008;3(5):472-476.
    • (2008) J Thorac Oncol , vol.3 , Issue.5 , pp. 472-476
    • Otani, H.1    Toyooka, S.2    Soh, J.3
  • 214
    • 76349090221 scopus 로고    scopus 로고
    • Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas
    • Dacic S, Shuai Y, Yousem S, Ohori P, Nikiforova M. Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas. Mod Pathol. 2010;23(2):159-168.
    • (2010) Mod Pathol , vol.23 , Issue.2 , pp. 159-168
    • Dacic, S.1    Shuai, Y.2    Yousem, S.3    Ohori, P.4    Nikiforova, M.5
  • 215
    • 67650441507 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
    • Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol. 2009;40(8):1152-1158.
    • (2009) Hum Pathol , vol.40 , Issue.8 , pp. 1152-1158
    • Boland, J.M.1    Erdogan, S.2    Vasmatzis, G.3
  • 216
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363(18):1693-1703.
    • (2010) N Engl J Med , vol.363 , Issue.18 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 217
    • 84929961675 scopus 로고    scopus 로고
    • ALK rearrangement testing and treatment patterns for patients with ALK-positive non-small cell lung cancer
    • Guerin A, Sasane M, Zhang J, et al. ALK rearrangement testing and treatment patterns for patients with ALK-positive non-small cell lung cancer. Cancer Epidemiol. 2015;39(3):307-312.
    • (2015) Cancer Epidemiol , vol.39 , Issue.3 , pp. 307-312
    • Guerin, A.1    Sasane, M.2    Zhang, J.3
  • 218
    • 84889888266 scopus 로고    scopus 로고
    • Rebiopsy of non-small cell lung cancer patients with acquired resistance to epidermal growth factor receptortyrosine kinase inhibitor: Comparison between T790M mutation-positive and mutation-negative populations
    • Hata A, Katakami N, Yoshioka H, et al. Rebiopsy of non-small cell lung cancer patients with acquired resistance to epidermal growth factor receptortyrosine kinase inhibitor: Comparison between T790M mutation-positive and mutation-negative populations. Cancer. 2013;119(24):4325-4332.
    • (2013) Cancer , vol.119 , Issue.24 , pp. 4325-4332
    • Hata, A.1    Katakami, N.2    Yoshioka, H.3
  • 219
    • 84887016132 scopus 로고    scopus 로고
    • Clinical implications of T790M mutation in patients with acquired resistance to EGFR tyrosine kinase inhibitors
    • Sun JM, Ahn MJ, Choi YL, Ahn JS, Park K. Clinical implications of T790M mutation in patients with acquired resistance to EGFR tyrosine kinase inhibitors. Lung Cancer. 2013;82(2):294-298.
    • (2013) Lung Cancer , vol.82 , Issue.2 , pp. 294-298
    • Sun, J.M.1    Ahn, M.J.2    Choi, Y.L.3    Ahn, J.S.4    Park, K.5
  • 220
    • 84906911022 scopus 로고    scopus 로고
    • Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations
    • Janjigian YY, Smit EF, Groen HJ, et al. Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations. Cancer Discov. 2014;4(9):1036-1045.
    • (2014) Cancer Discov , vol.4 , Issue.9 , pp. 1036-1045
    • Janjigian, Y.Y.1    Smit, E.F.2    Groen, H.J.3
  • 221
    • 84928739294 scopus 로고    scopus 로고
    • AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer
    • Janne PA, Yang JC, Kim DW, et al. AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer. N Engl J Med. 2015;372(18):1689-1699.
    • (2015) N Engl J Med , vol.372 , Issue.18 , pp. 1689-1699
    • Janne, P.A.1    Yang, J.C.2    Kim, D.W.3
  • 222
    • 84897910557 scopus 로고    scopus 로고
    • The predictive role of pretreatment epidermal growth factor receptor T790M mutation on the progression-free survival of tyrosine-kinase inhibitor-treated non-small cell lung cancer patients: A meta-analysis
    • Ding D, Yu Y, Li Z, Niu X, Lu S. The predictive role of pretreatment epidermal growth factor receptor T790M mutation on the progression-free survival of tyrosine-kinase inhibitor-treated non-small cell lung cancer patients: a meta-analysis. Onco Targets Ther. 2014;7:387-393.
    • (2014) Onco Targets Ther , vol.7 , pp. 387-393
    • Ding, D.1    Yu, Y.2    Li, Z.3    Niu, X.4    Lu, S.5
  • 223
    • 84904898065 scopus 로고    scopus 로고
    • AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer
    • Cross DA, Ashton SE, Ghiorghiu S, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014;4(9):1046-1061.
    • (2014) Cancer Discov , vol.4 , Issue.9 , pp. 1046-1061
    • Cross, D.A.1    Ashton, S.E.2    Ghiorghiu, S.3
  • 224
    • 84930582843 scopus 로고    scopus 로고
    • The next wave of EGFR tyrosine kinase inhibitors enter the clinic
    • Politi K, Ayeni D, Lynch T. The next wave of EGFR tyrosine kinase inhibitors enter the clinic. Cancer Cell. 2015;27(6):751-753.
    • (2015) Cancer Cell , vol.27 , Issue.6 , pp. 751-753
    • Politi, K.1    Ayeni, D.2    Lynch, T.3
  • 225
    • 79960085862 scopus 로고    scopus 로고
    • Optimization of dosing for EGFRmutant non-small cell lung cancer with evolutionary cancer modeling
    • doi:1126/scitranslmed.3002356
    • Chmielecki J, Foo J, Oxnard GR, et al. Optimization of dosing for EGFRmutant non-small cell lung cancer with evolutionary cancer modeling. Sci Transl Med. 2011;3(90):90ra59. doi:1126/scitranslmed.3002356.
    • (2011) Sci Transl Med , vol.3 , Issue.90 , pp. 90ra59
    • Chmielecki, J.1    Foo, J.2    Oxnard, G.R.3
  • 226
    • 38049150665 scopus 로고    scopus 로고
    • METamplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J, Brennan C, Shih JY, et al. METamplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci U S A. 2007;104(52):20932-20937.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.52 , pp. 20932-20937
    • Bean, J.1    Brennan, C.2    Shih, J.Y.3
  • 227
    • 33749435816 scopus 로고    scopus 로고
    • Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer
    • Engelman JA, Mukohara T, Zejnullahu K, et al. Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. J Clin Invest. 2006;116(10):2695-2706.
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2695-2706
    • Engelman, J.A.1    Mukohara, T.2    Zejnullahu, K.3
  • 228
    • 84949205332 scopus 로고    scopus 로고
    • EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291
    • Thress KS, Brant R, Carr TH, et al. EGFR mutation detection in ctDNA from NSCLC patient plasma: a cross-platform comparison of leading technologies to support the clinical development of AZD9291. Lung Cancer. 2015;90(3):509-515.
    • (2015) Lung Cancer , vol.90 , Issue.3 , pp. 509-515
    • Thress, K.S.1    Brant, R.2    Carr, T.H.3
  • 229
    • 84948071403 scopus 로고    scopus 로고
    • Mechanisms of acquired resistance to AZD9291: A mutation-selective, irreversible EGFR inhibitor
    • Kim TM, Song A, Kim DW, et al. Mechanisms of acquired resistance to AZD9291: a mutation-selective, irreversible EGFR inhibitor. J Thorac Oncol. 2015;10(12):1736-1744.
    • (2015) J Thorac Oncol , vol.10 , Issue.12 , pp. 1736-1744
    • Kim, T.M.1    Song, A.2    Kim, D.W.3
  • 230
    • 84987849616 scopus 로고    scopus 로고
    • Acquired resistance of EGFR-mutant lung cancer to a T790M-specific EGFR inhibitor: Emergence of a third mutation (C797S) in the EGFR tyrosine kinase domain
    • Yu HA, Tian SK, Drilon AE, et al. Acquired resistance of EGFR-mutant lung cancer to a T790M-specific EGFR inhibitor: emergence of a third mutation (C797S) in the EGFR tyrosine kinase domain. JAMA Oncol. 2015;1(7):982-984.
    • (2015) JAMA Oncol , vol.1 , Issue.7 , pp. 982-984
    • Yu, H.A.1    Tian, S.K.2    Drilon, A.E.3
  • 232
    • 84896539307 scopus 로고    scopus 로고
    • Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative nextgeneration genotyping of cell-free plasma DNA
    • Oxnard GR, Paweletz CP, Kuang Y, et al. Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative nextgeneration genotyping of cell-free plasma DNA. Clin Cancer Res. 2014;20(6): 1698-1705.
    • (2014) Clin Cancer Res , vol.20 , Issue.6 , pp. 1698-1705
    • Oxnard, G.R.1    Paweletz, C.P.2    Kuang, Y.3
  • 233
    • 84964746078 scopus 로고    scopus 로고
    • Circulating DNA addresses cancer monitoring in non small cell lung cancer patients for detection and capturing the dynamic changes of the disease
    • Wei Z, Shah N, Deng C, Xiao X, Zhong T, Li X. Circulating DNA addresses cancer monitoring in non small cell lung cancer patients for detection and capturing the dynamic changes of the disease. Springerplus. 2016;5:531. doi:10. 1186/s40064-016-2141-5.
    • (2016) Springerplus , vol.5 , pp. 531
    • Wei, Z.1    Shah, N.2    Deng, C.3    Xiao, X.4    Zhong, T.5    Li, X.6
  • 234
    • 84896737232 scopus 로고    scopus 로고
    • Quantitative identification of mutant alleles derived from lung cancer in plasma cell-free DNA via anomaly detection using deep sequencing data
    • Kukita Y, Uchida J, Oba S, et al. Quantitative identification of mutant alleles derived from lung cancer in plasma cell-free DNA via anomaly detection using deep sequencing data. PLoS One. 2013;8(11):e81468. doi:10.1371/journal. pone.0081468.
    • (2013) PLoS One , vol.8 , Issue.11 , pp. e81468
    • Kukita, Y.1    Uchida, J.2    Oba, S.3
  • 235
    • 84938399710 scopus 로고    scopus 로고
    • Detection and dynamic changes of EGFR mutations from circulating tumor DNA as a predictor of survival outcomes in NSCLC patients treated with first-line intercalated erlotinib and chemotherapy
    • Mok T, Wu YL, Lee JS, et al. Detection and dynamic changes of EGFR mutations from circulating tumor DNA as a predictor of survival outcomes in NSCLC patients treated with first-line intercalated erlotinib and chemotherapy. Clin Cancer Res. 2015;21(14):3196-3203.
    • (2015) Clin Cancer Res , vol.21 , Issue.14 , pp. 3196-3203
    • Mok, T.1    Wu, Y.L.2    Lee, J.S.3
  • 236
    • 84990050278 scopus 로고    scopus 로고
    • Association between plasma genotyping and outcomes of treatment with osimertinib (AZD9291) in advanced non-small-cell lung cancer
    • Oxnard GR, Thress KS, Alden RS, et al. Association between plasma genotyping and outcomes of treatment with osimertinib (AZD9291) in advanced non-small-cell lung cancer. J Clin Oncol. 2016;34(28):3375-3382.
    • (2016) J Clin Oncol , vol.34 , Issue.28 , pp. 3375-3382
    • Oxnard, G.R.1    Thress, K.S.2    Alden, R.S.3
  • 237
    • 84979222207 scopus 로고    scopus 로고
    • EGFR C797S mutation mediates resistance to third-generation inhibitors in T790M-positive non-small cell lung cancer
    • Wang S, Tsui ST, Liu C, Song Y, Liu D. EGFR C797S mutation mediates resistance to third-generation inhibitors in T790M-positive non-small cell lung cancer. J Hematol Oncol. 2016;9(1):59. doi:10.1186/s13045-016-0290-1.
    • (2016) J Hematol Oncol , vol.9 , Issue.1 , pp. 59
    • Wang, S.1    Tsui, S.T.2    Liu, C.3    Song, Y.4    Liu, D.5
  • 238
    • 84882668835 scopus 로고    scopus 로고
    • Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment
    • Huang D, Kim DW, Kotsakis A, et al. Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment. Genomics. 2013;102(3):157-162.
    • (2013) Genomics , vol.102 , Issue.3 , pp. 157-162
    • Huang, D.1    Kim, D.W.2    Kotsakis, A.3
  • 239
    • 77649222572 scopus 로고    scopus 로고
    • Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: Data from the randomized phase III INTEREST trial
    • Douillard JY, Shepherd FA, Hirsh V, et al. Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol. 2010;28(5):744-752.
    • (2010) J Clin Oncol , vol.28 , Issue.5 , pp. 744-752
    • Douillard, J.Y.1    Shepherd, F.A.2    Hirsh, V.3
  • 240
    • 79957458567 scopus 로고    scopus 로고
    • Cell-free nucleic acids as biomarkers in cancer patients
    • Schwarzenbach H, Hoon DS, Pantel K. Cell-free nucleic acids as biomarkers in cancer patients. Nat Rev Cancer. 2011;11(6):426-437.
    • (2011) Nat Rev Cancer , vol.11 , Issue.6 , pp. 426-437
    • Schwarzenbach, H.1    Hoon, D.S.2    Pantel, K.3
  • 241
    • 84896371874 scopus 로고    scopus 로고
    • Detection of circulating tumor DNA in early- and late-stage human malignancies
    • Bettegowda C, Sausen M, Leary RJ, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med. 2014;6(224): 224ra224. doi:10.1126/scitranslmed.3007094.
    • (2014) Sci Transl Med , vol.6 , Issue.224 , pp. 224ra224
    • Bettegowda, C.1    Sausen, M.2    Leary, R.J.3
  • 242
    • 84906250256 scopus 로고    scopus 로고
    • Gefitinib treatment in EGFR mutated Caucasian NSCLC: Circulating-free tumor DNA as a surrogate for determination of EGFR status
    • Douillard JY, Ostoros G, Cobo M, et al. Gefitinib treatment in EGFR mutated Caucasian NSCLC: circulating-free tumor DNA as a surrogate for determination of EGFR status. J Thorac Oncol. 2014;9(9):1345-1353.
    • (2014) J Thorac Oncol , vol.9 , Issue.9 , pp. 1345-1353
    • Douillard, J.Y.1    Ostoros, G.2    Cobo, M.3
  • 243
    • 84919471556 scopus 로고    scopus 로고
    • Insufficiency of peripheral blood as a substitute tissue for detecting EGFR mutations in lung cancer: A meta-analysis
    • Li Z, Zhang Y, Bao W, Jiang C. Insufficiency of peripheral blood as a substitute tissue for detecting EGFR mutations in lung cancer: a meta-analysis. Targeted Oncology. 2014;9(4):381-388.
    • (2014) Targeted Oncology , vol.9 , Issue.4 , pp. 381-388
    • Li, Z.1    Zhang, Y.2    Bao, W.3    Jiang, C.4
  • 244
    • 84925338452 scopus 로고    scopus 로고
    • Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
    • Jiang P, Chan CW, Chan KC, et al. Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients. Proc Natl Acad Sci U S A. 2015; 112(11):E1317-E1325.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.11 , pp. E1317-E1325
    • Jiang, P.1    Chan, C.W.2    Chan, K.C.3
  • 245
    • 80052436485 scopus 로고    scopus 로고
    • High fragmentation characterizes tumour-derived circulating DNA
    • Mouliere F, Robert B, Arnau Peyrotte E, et al. High fragmentation characterizes tumour-derived circulating DNA. PLoS One. 2011;6(9):e23418. doi:10.1371/journal.pone.0023418.
    • (2011) PLoS One , vol.6 , Issue.9 , pp. e23418
    • Mouliere, F.1    Robert, B.2    Arnau Peyrotte, E.3
  • 246
    • 0042173180 scopus 로고    scopus 로고
    • Increased plasma DNA integrity in cancer patients
    • Wang BG, Huang HY, Chen YC, et al. Increased plasma DNA integrity in cancer patients. Cancer Res. 2003;63(14):3966-3968.
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 3966-3968
    • Wang, B.G.1    Huang, H.Y.2    Chen, Y.C.3
  • 247
    • 84923059431 scopus 로고    scopus 로고
    • Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: A systematic review and metaanalysis
    • Luo J, Shen L, Zheng D. Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and metaanalysis. Sci Rep. 2014;4:6269. doi:10.1038/srep06269.
    • (2014) Sci Rep , vol.4 , pp. 6269
    • Luo, J.1    Shen, L.2    Zheng, D.3
  • 248
    • 84883458149 scopus 로고    scopus 로고
    • Detection of epidermal growth factor receptor T790M mutation in plasma DNA from patients refractory to epidermal growth factor receptor tyrosine kinase inhibitor
    • Sakai K, Horiike A, Irwin DL, et al. Detection of epidermal growth factor receptor T790M mutation in plasma DNA from patients refractory to epidermal growth factor receptor tyrosine kinase inhibitor. Cancer Sci. 2013;104(9):1198-1204.
    • (2013) Cancer Sci , vol.104 , Issue.9 , pp. 1198-1204
    • Sakai, K.1    Horiike, A.2    Irwin, D.L.3
  • 249
    • 84914703538 scopus 로고    scopus 로고
    • Quantification and dynamic monitoring of EGFR T790M in plasma cell-free DNA by digital PCR for prognosis of EGFR-TKI treatment in advanced NSCLC
    • Wang Z, Chen R,Wang S, et al. Quantification and dynamic monitoring of EGFR T790M in plasma cell-free DNA by digital PCR for prognosis of EGFR-TKI treatment in advanced NSCLC. PLoS One. 2014;9(11):e110780. doi:10.1371/journal.pone.0110780.
    • (2014) PLoS One , vol.9 , Issue.11 , pp. e110780
    • Wang, Z.1    Chen, R.2    Wang, S.3
  • 250
    • 85008239423 scopus 로고    scopus 로고
    • Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): A phase 3, open-label, multicentre randomised controlled trial
    • Rittmeyer A, Barlesi F,Waterkamp D, et al. Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial. Lancet. 2017;389(10066): 255-265.
    • (2017) Lancet , vol.389 , Issue.1066 , pp. 255-265
    • Rittmeyer, A.1    Barlesi, F.2    Waterkamp, D.3
  • 251
    • 84950117835 scopus 로고    scopus 로고
    • Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): A randomised controlled trial
    • 10027
    • Herbst RS, Baas P, Kim DW, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet. 2016;387(10027):1540-1550.
    • (2016) Lancet , vol.387 , pp. 1540-1550
    • Herbst, R.S.1    Baas, P.2    Kim, D.W.3
  • 252
    • 84994802263 scopus 로고    scopus 로고
    • Pembrolizumab versus chemotherapy for PD-L1-positive non-small-cell lung cancer
    • Reck M, Rodriguez-Abreu D, Robinson AG, et al. Pembrolizumab versus chemotherapy for PD-L1-positive non-small-cell lung cancer. N Engl J Med. 2016;375(19):1823-1833.
    • (2016) N Engl J Med , vol.375 , Issue.19 , pp. 1823-1833
    • Reck, M.1    Rodriguez-Abreu, D.2    Robinson, A.G.3
  • 253
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 2015;373(17): 1627-1639.
    • (2015) N Engl J Med , vol.373 , Issue.17 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3
  • 254
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
    • Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373(2): 123-135.
    • (2015) N Engl J Med , vol.373 , Issue.2 , pp. 123-135
    • Brahmer, J.1    Reckamp, K.L.2    Baas, P.3
  • 257
    • 85042658015 scopus 로고    scopus 로고
    • US Food and Drug Administration. Updated October 19, 2016. Accessed June 14, 2017
    • US Food and Drug Administration. Atezolizumab (TECENTRIQ). US Food and Drug Administration Web site. ht tps://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm525780.htm. Updated October 19, 2016. Accessed June 14, 2017.
    • Atezolizumab (TECENTRIQ). US Food and Drug Administration
  • 258
    • 84964039838 scopus 로고    scopus 로고
    • Programmed death ligand-1 immunohistochemistry- A new challenge for pathologists: A perspective from members of the Pulmonary Pathology Society
    • Sholl LM, Aisner DL, Allen TC, et al. Programmed death ligand-1 immunohistochemistry- A new challenge for pathologists: a perspective from members of the Pulmonary Pathology Society. Arch Pathol Lab Med. 2016;140(4): 341-344.
    • (2016) Arch Pathol Lab Med , vol.140 , Issue.4 , pp. 341-344
    • Sholl, L.M.1    Aisner, D.L.2    Allen, T.C.3
  • 259
    • 85042344755 scopus 로고    scopus 로고
    • Whitehouse Station NJ: Merck & Co, Inc
    • KEYTRUDA [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2014.
    • (2014) KEYTRUDA [Package Insert]
  • 260
    • 84960094819 scopus 로고    scopus 로고
    • Princeton NJ: Bristol-Myers Squibb Company
    • OPDIVO [package insert]. Princeton, NJ: Bristol-Myers Squibb Company; 2015.
    • (2015) OPDIVO [Package Insert]
  • 261
    • 85020470789 scopus 로고    scopus 로고
    • South San Francisco CA: Genentech, Inc
    • TECENTRIQ [package insert]. South San Francisco, CA: Genentech, Inc; 2016.
    • (2016) TECENTRIQ [Package Insert]
  • 262
    • 79951955198 scopus 로고    scopus 로고
    • GRADE guidelines, 3: Rating the quality of evidence
    • Balshem H, Helfand M, Schunemann HJ, et al. GRADE guidelines, 3: rating the quality of evidence. J Clin Epidemiol. 2011;64(4):401-406.
    • (2011) J Clin Epidemiol , vol.64 , Issue.4 , pp. 401-406
    • Balshem, H.1    Helfand, M.2    Schunemann, H.J.3
  • 263
    • 84878246578 scopus 로고    scopus 로고
    • GRADE guidelines, 14: Going from evidence to recommendations: The significance and presentation of recommendations
    • Andrews J, Guyatt G, Oxman AD, et al. GRADE guidelines, 14: going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol. 2013;66(7):719-725.
    • (2013) J Clin Epidemiol , vol.66 , Issue.7 , pp. 719-725
    • Andrews, J.1    Guyatt, G.2    Oxman, A.D.3


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