-
1
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
The Cancer Genome Atlas Research N. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014;511:543-50.
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
The Cancer Genome Atlas Research N1
-
2
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao W, Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011;12:175-80.
-
(2011)
Lancet Oncol
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
3
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF. Met, metastasis, motility and more. Nat Rev Mol Cell Biol 2003;4:915-25.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
4
-
-
33947207989
-
Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival
-
Lutterbach B, Zeng Q, Davis LJ, Hatch H, Hang G, Kohl NE, et al. Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. Cancer Res 2007;67:2081-8.
-
(2007)
Cancer Res
, vol.67
, pp. 2081-2088
-
-
Lutterbach, B.1
Zeng, Q.2
Davis, L.J.3
Hatch, H.4
Hang, G.5
Kohl, N.E.6
-
5
-
-
84891746435
-
Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement
-
Schwab R, Petak I, Kollar M, Pinter F, Varkondi E, Kohanka A, et al. Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement. Lung Cancer 2014;83:109-11.
-
(2014)
Lung Cancer
, vol.83
, pp. 109-111
-
-
Schwab, R.1
Petak, I.2
Kollar, M.3
Pinter, F.4
Varkondi, E.5
Kohanka, A.6
-
6
-
-
79955458487
-
Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification
-
Ou SH, Kwak EL, Siwak-Tapp C, Dy J, Bergethon K, Clark JW, et al. Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol 2011;6:942-6.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 942-946
-
-
Ou, S.H.1
Kwak, E.L.2
Siwak-Tapp, C.3
Dy, J.4
Bergethon, K.5
Clark, J.W.6
-
7
-
-
31544462584
-
Somatic mutations lead to an oncogenic deletion of met in lung cancer
-
Kong-Beltran M, Seshagiri S, Zha J, Zhu W, Bhawe K, Mendoza N, et al. Somatic mutations lead to an oncogenic deletion of met in lung cancer. Cancer Res 2006;66:283-9.
-
(2006)
Cancer Res
, vol.66
, pp. 283-289
-
-
Kong-Beltran, M.1
Seshagiri, S.2
Zha, J.3
Zhu, W.4
Bhawe, K.5
Mendoza, N.6
-
8
-
-
61549138135
-
Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers
-
Onozato R, Kosaka T, Kuwano H, Sekido Y, Yatabe Y, Mitsudomi T. Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers. J Thorac Oncol 2009;4:5-11.
-
(2009)
J Thorac Oncol
, vol.4
, pp. 5-11
-
-
Onozato, R.1
Kosaka, T.2
Kuwano, H.3
Sekido, Y.4
Yatabe, Y.5
Mitsudomi, T.6
-
9
-
-
84938815085
-
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
-
Paik PK, Drilon A, Fan PD, Yu H, Rekhtman N, Ginsberg MS, et al. Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer Discov 2015;5:842-9.
-
(2015)
Cancer Discov
, vol.5
, pp. 842-849
-
-
Paik, P.K.1
Drilon, A.2
Fan, P.D.3
Yu, H.4
Rekhtman, N.5
Ginsberg, M.S.6
-
10
-
-
84904679830
-
Onartuzumab plus erlotinib versus erlotinib in previously treated stage IIb or IV NSCLC: Results from the pivotal phase III randomized, multicenter, placebo-controlled METLung (OAM4971g) global trial
-
Spigel DR, Edelman MJ, O'Byrne K, Paz-Ares L, Shames DS, Yu W, et al. Onartuzumab plus erlotinib versus erlotinib in previously treated stage IIb or IV NSCLC: Results from the pivotal phase III randomized, multicenter, placebo-controlled METLung (OAM4971g) global trial. J Clin Oncol 32:5s, 2014 (suppl; abstr 8000).
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Spigel, D.R.1
Edelman, M.J.2
O'Byrne, K.3
Paz-Ares, L.4
Shames, D.S.5
Yu, W.6
-
11
-
-
84940110053
-
Profiling of oncogenic driver events in lung adenocarcinoma revealed MET mutation as independent prognostic factor
-
Yeung SF, Tong JH, Law PP, Chung LY, Lung RW, Tong CY, et al. Profiling of oncogenic driver events in lung adenocarcinoma revealed MET mutation as independent prognostic factor. J Thorac Oncol 2015;10:1292-300.
-
(2015)
J Thorac Oncol
, vol.10
, pp. 1292-1300
-
-
Yeung, S.F.1
Tong, J.H.2
Law, P.P.3
Chung, L.Y.4
Lung, R.W.5
Tong, C.Y.6
-
12
-
-
84862777005
-
Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer
-
Dziadziuszko R, Wynes MW, Singh S, Asuncion BR, Ranger-Moore J, Konopa K, et al. Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer. J Thorac Oncol 2012;7:340-7.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 340-347
-
-
Dziadziuszko, R.1
Wynes, M.W.2
Singh, S.3
Asuncion, B.R.4
Ranger-Moore, J.5
Konopa, K.6
-
13
-
-
63849163410
-
Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
-
Cappuzzo F, Marchetti A, Skokan M, Rossi E, Gajapathy S, Felicioni L, et al. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. J Clin Oncol 2009;27:1667-74.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1667-1674
-
-
Cappuzzo, F.1
Marchetti, A.2
Skokan, M.3
Rossi, E.4
Gajapathy, S.5
Felicioni, L.6
-
14
-
-
83555165138
-
Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients
-
Tanaka A, Sueoka-Aragane N, Nakamura T, Takeda Y, Mitsuoka M, Yamasaki F, et al. Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients. Lung Cancer 2012;75:89-94.
-
(2012)
Lung Cancer
, vol.75
, pp. 89-94
-
-
Tanaka, A.1
Sueoka-Aragane, N.2
Nakamura, T.3
Takeda, Y.4
Mitsuoka, M.5
Yamasaki, F.6
-
15
-
-
84922537173
-
Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing
-
Jurmeister P, Lenze D, Berg E, Mende S, Schaper F, Kellner U, et al. Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing. Lung Cancer 2015;87:122-9.
-
(2015)
Lung Cancer
, vol.87
, pp. 122-129
-
-
Jurmeister, P.1
Lenze, D.2
Berg, E.3
Mende, S.4
Schaper, F.5
Kellner, U.6
-
16
-
-
84858335323
-
c-MET/phospho-MET protein expression and MET gene copy number in nonsmall cell lung carcinomas
-
Tsuta K, Kozu Y, Mimae T, Yoshida A, Kohno T, Sekine I, et al. c-MET/phospho-MET protein expression and MET gene copy number in nonsmall cell lung carcinomas. J Thorac Oncol 2012;7:331-9.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 331-339
-
-
Tsuta, K.1
Kozu, Y.2
Mimae, T.3
Yoshida, A.4
Kohno, T.5
Sekine, I.6
-
17
-
-
84938222817
-
MET mutation associated with responsiveness to crizotinib
-
Waqar SN, Morgensztern D, Sehn J. MET mutation associated with responsiveness to crizotinib. J Thorac Oncol 2015;10:e29-31.
-
(2015)
J Thorac Oncol
, vol.10
, pp. e29-e31
-
-
Waqar, S.N.1
Morgensztern, D.2
Sehn, J.3
-
18
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012;150:1107-20.
-
(2012)
Cell
, vol.150
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
Hernandez, B.4
Pugh, T.J.5
Hodis, E.6
-
19
-
-
84941420654
-
Response to crizotinib in a patient with lung adenocarcinoma harboring a MET splice site mutation
-
Jenkins RW, Oxnard GR, Elkin S, Sullivan EK, Carter JL, Barbie DA. Response to crizotinib in a patient with lung adenocarcinoma harboring a MET splice site mutation. Clin Lung Cancer 2015;16:E101-4.
-
(2015)
Clin Lung Cancer
, vol.16
, pp. E101-E104
-
-
Jenkins, R.W.1
Oxnard, G.R.2
Elkin, S.3
Sullivan, E.K.4
Carter, J.L.5
Barbie, D.A.6
-
20
-
-
84975042459
-
MET mutations in non-small cell lung cancer: Four case reports of mutations at or near the splice junction for exon 14
-
Azzato EM, Desphande C, Gabriel C, Langer C, Evans T, Gault CR, et al. MET mutations in non-small cell lung cancer: four case reports of mutations at or near the splice junction for exon 14. J OncoPathol 2014;2:65.
-
(2014)
J OncoPathol
, vol.2
, pp. 65
-
-
Azzato, E.M.1
Desphande, C.2
Gabriel, C.3
Langer, C.4
Evans, T.5
Gault, C.R.6
-
21
-
-
84868309107
-
The transcriptional landscape and mutational profile of lung adenocarcinoma
-
Seo JS, Ju YS, Lee WC, Shin JY, Lee JK, Bleazard T, et al. The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res 2012;22:2109-19.
-
(2012)
Genome Res
, vol.22
, pp. 2109-2119
-
-
Seo, J.S.1
Ju, Y.S.2
Lee, W.C.3
Shin, J.Y.4
Lee, J.K.5
Bleazard, T.6
-
22
-
-
55449116539
-
Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer
-
Okuda K, Sasaki H, Yukiue H, Yano M, Fujii Y. Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer. Cancer Sci 2008;99:2280-5.
-
(2008)
Cancer Sci
, vol.99
, pp. 2280-2285
-
-
Okuda, K.1
Sasaki, H.2
Yukiue, H.3
Yano, M.4
Fujii, Y.5
-
23
-
-
84923122292
-
MET amplification status in therapy-naive adeno- and squamous cell carcinomas of the lung
-
Schildhaus HU, Schultheis AM, Ruschoff J, Binot E, Merkelbach-Bruse S, Fassunke J, et al. MET amplification status in therapy-naive adeno- and squamous cell carcinomas of the lung. Clin Cancer Res 2015;21:907-15.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 907-915
-
-
Schildhaus, H.U.1
Schultheis, A.M.2
Ruschoff, J.3
Binot, E.4
Merkelbach-Bruse, S.5
Fassunke, J.6
-
24
-
-
70449433271
-
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells
-
Soh J, Okumura N, Lockwood WW, Yamamoto H, Shigematsu H, Zhang W, et al. Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells. PLoS One 2009;4:e7464.
-
(2009)
PLoS One
, vol.4
-
-
Soh, J.1
Okumura, N.2
Lockwood, W.W.3
Yamamoto, H.4
Shigematsu, H.5
Zhang, W.6
-
25
-
-
77950859967
-
Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion
-
Asaoka Y, Tada M, Ikenoue T, Seto M, Imai M, Miyabayashi K, et al. Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion. Biochem Biophys Res Commun 2010;394:1042-6.
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 1042-1046
-
-
Asaoka, Y.1
Tada, M.2
Ikenoue, T.3
Seto, M.4
Imai, M.5
Miyabayashi, K.6
-
26
-
-
20044381123
-
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
-
Stephens P, Edkins S, Davies H, Greenman C, Cox C, Hunter C, et al. A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nat Genet 2005;37:590-2.
-
(2005)
Nat Genet
, vol.37
, pp. 590-592
-
-
Stephens, P.1
Edkins, S.2
Davies, H.3
Greenman, C.4
Cox, C.5
Hunter, C.6
-
27
-
-
84947874927
-
Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations
-
Jul 27. [Epub ahead of print]
-
Liu X, Jia Y, Stoopler MB, Shen Y, Cheng H, Chen J, et al. Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations. J Clin Oncol . 2015Jul 27. [Epub ahead of print].
-
(2015)
J Clin Oncol
-
-
Liu, X.1
Jia, Y.2
Stoopler, M.B.3
Shen, Y.4
Cheng, H.5
Chen, J.6
-
28
-
-
84884892474
-
Pulmonary sarcomatoid carcinoma: A clinicopathologic study and prognostic analysis of 51 cases
-
Huang SY, Shen SJ, Li XY. Pulmonary sarcomatoid carcinoma: a clinicopathologic study and prognostic analysis of 51 cases. World J Surg Oncol 2013;11:252.
-
(2013)
World J Surg Oncol
, vol.11
, pp. 252
-
-
Huang, S.Y.1
Shen, S.J.2
Li, X.Y.3
-
29
-
-
75149148710
-
Sarcomatoid carcinoma of the lung: Histologic criteria and common lesions in the differential diagnosis
-
Franks TJ, Galvin JR. Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis. Arch Pathol Lab Med 2010;134:49-54.
-
(2010)
Arch Pathol Lab Med
, vol.134
, pp. 49-54
-
-
Franks, T.J.1
Galvin, J.R.2
-
30
-
-
77949881940
-
Review article: Pulmonary sarcomatoid carcinomas: A practical overview
-
Pelosi G, Sonzogni A, De Pas T, Galetta D, Veronesi G, Spaggiari L, et al. Review article: pulmonary sarcomatoid carcinomas: a practical overview. Int J Surg Pathol 2010;18:103-20.
-
(2010)
Int J Surg Pathol
, vol.18
, pp. 103-120
-
-
Pelosi, G.1
Sonzogni, A.2
De Pas, T.3
Galetta, D.4
Veronesi, G.5
Spaggiari, L.6
-
32
-
-
84959898696
-
Negative results of METLung study: An opportunity to better understand the role of MET pathway in advanced NSCLC
-
Perol M. Negative results of METLung study: an opportunity to better understand the role of MET pathway in advanced NSCLC. Transl Lung Cancer Res 2014;3:392-4.
-
(2014)
Transl Lung Cancer Res
, vol.3
, pp. 392-394
-
-
Perol, M.1
-
33
-
-
84997941720
-
An overview of the c-MET signaling pathway
-
Organ SL, Tsao MS. An overview of the c-MET signaling pathway. Ther Adv Med Oncol 2011;3:S7-19.
-
(2011)
Ther Adv Med Oncol
, vol.3
, pp. S7-S19
-
-
Organ, S.L.1
Tsao, M.S.2
|