Detection of ROS1 gene rearrangement in lung adenocarcinoma: Comparison of IHC, FISH and real-time RT-PCR

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Shan, Ling ^a   Lian, Fang ^a   Guo, Lei ^a   Qiu, Tian ^a   Ling, Yun ^a   Ying, Jianming ^a   Lin, Dongmei ^b  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CRIZOTINIB; PROTEIN ROS1; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; ONCOPROTEIN; PROTEIN TYROSINE KINASE; ROS1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER PATIENT; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; MOLECULARLY TARGETED THERAPY; PATIENT SELECTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROS1 GENE; SENSITIVITY AND SPECIFICITY; TISSUE MICROARRAY; ADENOCARCINOMA; COMPARATIVE STUDY; GENETICS; LUNG TUMOR; METABOLISM; MIDDLE AGED; PROCEDURES; VERY ELDERLY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; FEMALE; GENE REARRANGEMENT; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; MALE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84924310226     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120422     Document Type: Article

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