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Volumn 2017, Issue , 2017, Pages

Toll-Like Receptor 4 Signalling and Its Impact on Platelet Function, Thrombosis, and Haemostasis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4;

EID: 85042589594     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2017/9605894     Document Type: Review
Times cited : (73)

References (101)
  • 1
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: Bridging inflammation and cardiovascular disease
    • P. Von Hundelshausen and C. Weber, "Platelets as immune cells: bridging inflammation and cardiovascular disease," Circulation Research, vol. 100, no. 1, pp. 27-40, 2007.
    • (2007) Circulation Research , vol.100 , Issue.1 , pp. 27-40
    • Von Hundelshausen, P.1    Weber, C.2
  • 3
    • 84960421444 scopus 로고    scopus 로고
    • Circular RNA enrichment in platelets is a signature of transcriptome degradation
    • A. A. Alhasan, O. G. Izuogu, H. H. Al-Balool et al., "Circular RNA enrichment in platelets is a signature of transcriptome degradation," Blood, vol. 127, no. 9, pp. e1-e11, 2016.
    • (2016) Blood , vol.127 , Issue.9 , pp. e1-e11
    • Alhasan, A.A.1    Izuogu, O.G.2    Al-Balool, H.H.3
  • 4
  • 5
    • 33845606632 scopus 로고    scopus 로고
    • Activation of platelet function through G protein-coupled receptors
    • S. Offermanns, "Activation of platelet function through G protein-coupled receptors," Circulation Research, vol. 99, no. 12, pp. 1293-1304, 2006.
    • (2006) Circulation Research , vol.99 , Issue.12 , pp. 1293-1304
    • Offermanns, S.1
  • 6
    • 85003441493 scopus 로고    scopus 로고
    • Platelets and infection
    • C. Deppermann and P. Kubes, "Platelets and infection," Seminars in Immunology, vol. 28, no. 6, pp. 536-545, 2016.
    • (2016) Seminars in Immunology , vol.28 , Issue.6 , pp. 536-545
    • Deppermann, C.1    Kubes, P.2
  • 7
    • 39749109478 scopus 로고    scopus 로고
    • Triggers, targets and treatments for thrombosis
    • N. Mackman, "Triggers, targets and treatments for thrombosis," Nature, vol. 451, no. 7181, pp. 914-918, 2008.
    • (2008) Nature , vol.451 , Issue.7181 , pp. 914-918
    • Mackman, N.1
  • 8
    • 84947331485 scopus 로고    scopus 로고
    • Enhanced platelet Toll-like receptor 2 and 4 expression in acute coronary syndrome and stable angina pectoris
    • K. M. Gurses, D. Kocyigit, M. U. Yalcin et al., "Enhanced platelet Toll-like receptor 2 and 4 expression in acute coronary syndrome and stable angina pectoris," The American Journal of Cardiology, vol. 116, no. 11, pp. 1666-1671, 2015.
    • (2015) The American Journal of Cardiology , vol.116 , Issue.11 , pp. 1666-1671
    • Gurses, K.M.1    Kocyigit, D.2    Yalcin, M.U.3
  • 9
    • 84964693394 scopus 로고    scopus 로고
    • Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4
    • P. Prakash, P. P. Kulkarni, S. R. Lentz, and A. K. Chauhan, "Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4," Blood, vol. 125, no. 20, pp. 3164-3172, 2015.
    • (2015) Blood , vol.125 , Issue.20 , pp. 3164-3172
    • Prakash, P.1    Kulkarni, P.P.2    Lentz, S.R.3    Chauhan, A.K.4
  • 10
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • P. Libby, "Inflammation in atherosclerosis," Nature, vol. 420, no. 6917, pp. 868-874, 2002.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 868-874
    • Libby, P.1
  • 11
    • 76949093731 scopus 로고    scopus 로고
    • The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes
    • L. M. Beaulieu and J. E. Freedman, "The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes," Thrombosis Research, vol. 125, no. 3, pp. 205-209, 2010.
    • (2010) Thrombosis Research , vol.125 , Issue.3 , pp. 205-209
    • Beaulieu, L.M.1    Freedman, J.E.2
  • 12
    • 84926672796 scopus 로고    scopus 로고
    • The inflammatory role of platelets via their TLRs and Siglec receptors
    • F. Cognasse, K. A. Nguyen, P. Damien et al., "The inflammatory role of platelets via their TLRs and Siglec receptors," Frontiers in Immunology, vol. 6, no. 83, pp. 1-15, 2015.
    • (2015) Frontiers in Immunology , vol.6 , Issue.83 , pp. 1-15
    • Cognasse, F.1    Nguyen, K.A.2    Damien, P.3
  • 13
    • 84901463729 scopus 로고    scopus 로고
    • Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αiIbβ3, and platelet factor 4
    • M. Arman, K. Krauel, D. O. Tilley et al., "Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4," Blood, vol. 123, no. 20, pp. 3166-3174, 2014.
    • (2014) Blood , vol.123 , Issue.20 , pp. 3166-3174
    • Arman, M.1    Krauel, K.2    Tilley, D.O.3
  • 14
    • 33645579382 scopus 로고    scopus 로고
    • Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome
    • A. L. Ståhl, M. Svensson, M. Mörgelin et al., "Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome," Blood, vol. 108, no. 1, pp. 167-176, 2006.
    • (2006) Blood , vol.108 , Issue.1 , pp. 167-176
    • Ståhl, A.L.1    Svensson, M.2    Mörgelin, M.3
  • 15
    • 0036625057 scopus 로고    scopus 로고
    • Host defense role of platelets: Engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation
    • T. Youssefian, A. Drouin, J. M. Massé, J. Guichard, and E. M. Cramer, "Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation," Blood, vol. 99, no. 11, pp. 4021-4029, 2002.
    • (2002) Blood , vol.99 , Issue.11 , pp. 4021-4029
    • Youssefian, T.1    Drouin, A.2    Massé, J.M.3    Guichard, J.4    Cramer, E.M.5
  • 16
    • 34249310057 scopus 로고    scopus 로고
    • Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets
    • J. W. Semple, R. Aslam, M. Kim, E. R. Speck, and J. Freedman, "Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets," Blood, vol. 109, no. 11, pp. 4803-4805, 2007.
    • (2007) Blood , vol.109 , Issue.11 , pp. 4803-4805
    • Semple, J.W.1    Aslam, R.2    Kim, M.3    Speck, E.R.4    Freedman, J.5
  • 18
    • 84864077185 scopus 로고    scopus 로고
    • Plateletderived Toll-like receptor 4 (TLR-4) is sufficient to promote microvascular thrombosis in endotoxemia
    • R. J. Stark, N. Aghakasiri, and R. E. Rumbaut, "Plateletderived Toll-like receptor 4 (TLR-4) is sufficient to promote microvascular thrombosis in endotoxemia," PLoS One, vol. 7, no. 7, article e41254, 2012.
    • (2012) PLoS One , vol.7 , Issue.7
    • Stark, R.J.1    Aghakasiri, N.2    Rumbaut, R.E.3
  • 22
    • 34147188469 scopus 로고    scopus 로고
    • Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
    • S. R. Clark, A. C. Ma, S. A. Tavener et al., "Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood," Nature Medicine, vol. 13, no. 4, pp. 463-469, 2007.
    • (2007) Nature Medicine , vol.13 , Issue.4 , pp. 463-469
    • Clark, S.R.1    Ma, A.C.2    Tavener, S.A.3
  • 23
    • 84941924565 scopus 로고    scopus 로고
    • Controversial role of Toll-like receptor 4 in adult stem cells
    • M. Zeuner, K. Bieback, and D. Widera, "Controversial role of Toll-like receptor 4 in adult stem cells," Stem Cell Reviews and Reports, vol. 11, no. 4, pp. 621-634, 2015.
    • (2015) Stem Cell Reviews and Reports , vol.11 , Issue.4 , pp. 621-634
    • Zeuner, M.1    Bieback, K.2    Widera, D.3
  • 24
    • 77249160271 scopus 로고    scopus 로고
    • Localisation and trafficking of Toll-like receptors: An important mode of regulation
    • A. F. McGettrick and L. A. O'Neill, "Localisation and trafficking of Toll-like receptors: an important mode of regulation," Current Opinion in Immunology, vol. 22, no. 1, pp. 20-27, 2010.
    • (2010) Current Opinion in Immunology , vol.22 , Issue.1 , pp. 20-27
    • McGettrick, A.F.1    O'Neill, L.A.2
  • 25
    • 84929093894 scopus 로고    scopus 로고
    • MALT1-ubiquitination triggers non-genomic NF-kB/IKK signaling upon platelet activation
    • Z. A. Karim, H. P. Vemana, and F. T. Khasawneh, "MALT1-ubiquitination triggers non-genomic NF-kB/IKK signaling upon platelet activation," PLoS One, vol. 10, no. 3, article e0119363, 2015.
    • (2015) PLoS One , vol.10 , Issue.3
    • Karim, Z.A.1    Vemana, H.P.2    Khasawneh, F.T.3
  • 26
    • 84892365016 scopus 로고    scopus 로고
    • Regulation of platelet responses triggered by Toll-like receptor 2 and 4 ligands is another non-genomic role of nuclear factorkappaB
    • L. Rivadeneyra, A. Carestia, J. Etulain et al., "Regulation of platelet responses triggered by Toll-like receptor 2 and 4 ligands is another non-genomic role of nuclear factorkappaB," Thrombosis Research, vol. 133, no. 2, pp. 235-243, 2014.
    • (2014) Thrombosis Research , vol.133 , Issue.2 , pp. 235-243
    • Rivadeneyra, L.1    Carestia, A.2    Etulain, J.3
  • 27
    • 84860832650 scopus 로고    scopus 로고
    • Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
    • U. Ohto, K. Fukase, K. Miyake, and T. Shimizu, "Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2," Proceedings of the National Academy of Sciences, vol. 109, no. 19, pp. 7421-7426, 2012.
    • (2012) Proceedings of the National Academy of Sciences , vol.109 , Issue.19 , pp. 7421-7426
    • Ohto, U.1    Fukase, K.2    Miyake, K.3    Shimizu, T.4
  • 28
    • 0028899305 scopus 로고
    • Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14
    • J. A. Gegner, R. J. Ulevitch, and P. S. Tobias, "Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14," Journal of Biological Chemistry, vol. 270, no. 10, pp. 5320-5325, 1995.
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.10 , pp. 5320-5325
    • Gegner, J.A.1    Ulevitch, R.J.2    Tobias, P.S.3
  • 29
    • 84961223821 scopus 로고    scopus 로고
    • Structure and function: Lipid A modifications in commensals and pathogens
    • A. Steimle, I. B. Autenrieth, and J. S. Frick, "Structure and function: lipid A modifications in commensals and pathogens," International Journal of Medical Microbiology, vol. 306, no. 5, pp. 290-301, 2016.
    • (2016) International Journal of Medical Microbiology , vol.306 , Issue.5 , pp. 290-301
    • Steimle, A.1    Autenrieth, I.B.2    Frick, J.S.3
  • 30
    • 40449109127 scopus 로고    scopus 로고
    • Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets
    • F. Cognasse, H. Hamzeh-Cognasse, S. Lafarge et al., "Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets," British Journal of Haematology, vol. 141, no. 1, pp. 84-91, 2008.
    • (2008) British Journal of Haematology , vol.141 , Issue.1 , pp. 84-91
    • Cognasse, F.1    Hamzeh-Cognasse, H.2    Lafarge, S.3
  • 32
    • 84948807307 scopus 로고    scopus 로고
    • Platelet-derived HMGB1 is a critical mediator of thrombosis
    • S. Vogel, R. Bodenstein, Q. Chen et al., "Platelet-derived HMGB1 is a critical mediator of thrombosis," Journal of Clinical Investigation, vol. 125, no. 12, pp. 4638-4654, 2015.
    • (2015) Journal of Clinical Investigation , vol.125 , Issue.12 , pp. 4638-4654
    • Vogel, S.1    Bodenstein, R.2    Chen, Q.3
  • 33
  • 34
    • 84860879114 scopus 로고    scopus 로고
    • Endotoxin.albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4
    • G. A. Esparza, A. Teghanemt, D. Zhang, T. L. Gioannini, and J. P. Weiss, "Endotoxin.albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4," Innate Immunity, vol. 18, no. 3, pp. 478-491, 2012.
    • (2012) Innate Immunity , vol.18 , Issue.3 , pp. 478-491
    • Esparza, G.A.1    Teghanemt, A.2    Zhang, D.3    Gioannini, T.L.4    Weiss, J.P.5
  • 35
    • 0037033015 scopus 로고    scopus 로고
    • An essential role for albumin in the interaction of endotoxin with lipopolysaccharide-binding protein and sCD14 and resultant cell activation
    • T. L. Gioannini, D. Zhang, A. Teghanemt, and J. P. Weiss, "An essential role for albumin in the interaction of endotoxin with lipopolysaccharide-binding protein and sCD14 and resultant cell activation," Journal of Biological Chemistry, vol. 277, no. 49, pp. 47818-47825, 2002.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.49 , pp. 47818-47825
    • Gioannini, T.L.1    Zhang, D.2    Teghanemt, A.3    Weiss, J.P.4
  • 36
    • 27144539508 scopus 로고    scopus 로고
    • Platelets express functional Toll-like receptor-4 (TLR4)
    • G. Andonegui, S. Kerfoot, K. McNagny, K. Ebbert, K. Patel, and P. Kubes, "Platelets express functional Toll-like receptor-4 (TLR4)," Blood, vol. 106, no. 7, pp. 2417-2423, 2005.
    • (2005) Blood , vol.106 , Issue.7 , pp. 2417-2423
    • Andonegui, G.1    Kerfoot, S.2    McNagny, K.3    Ebbert, K.4    Patel, K.5    Kubes, P.6
  • 37
    • 67349182481 scopus 로고    scopus 로고
    • The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
    • B. S. Park, D. H. Song, H. M. Kim, B. S. Choi, H. Lee, and J. O. Lee, "The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex," Nature, vol. 458, no. 7242, pp. 1191-1195, 2009.
    • (2009) Nature , vol.458 , Issue.7242 , pp. 1191-1195
    • Park, B.S.1    Song, D.H.2    Kim, H.M.3    Choi, B.S.4    Lee, H.5    Lee, J.O.6
  • 38
    • 0036301797 scopus 로고    scopus 로고
    • Essential role of MD-2 in LPS responsiveness and TLR4 distribution
    • Y. Nagai, S. Akashi, M. Nagafuku et al., "Essential role of MD-2 in LPS responsiveness and TLR4 distribution," Nature Immunology, vol. 3, no. 7, pp. 667-672, 2002.
    • (2002) Nature Immunology , vol.3 , Issue.7 , pp. 667-672
    • Nagai, Y.1    Akashi, S.2    Nagafuku, M.3
  • 39
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • R. Shimazu, S. Akashi, H. Ogata et al., "MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4," The Journal of Experimental Medicine, vol. 189, no. 11, pp. 1777-1782, 1999.
    • (1999) The Journal of Experimental Medicine , vol.189 , Issue.11 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3
  • 40
    • 84899461458 scopus 로고    scopus 로고
    • LPS or ethanol triggers clathrin-and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes
    • M. Pascual-Lucas, S. Fernandez-Lizarbe, J. Montesinos, and C. Guerri, "LPS or ethanol triggers clathrin-and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes," Journal of Neurochemistry, vol. 129, no. 3, pp. 448-462, 2014.
    • (2014) Journal of Neurochemistry , vol.129 , Issue.3 , pp. 448-462
    • Pascual-Lucas, M.1    Fernandez-Lizarbe, S.2    Montesinos, J.3    Guerri, C.4
  • 42
    • 30444436765 scopus 로고    scopus 로고
    • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
    • R. Aslam, E. R. Speck, M. Kim et al., "Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo," Blood, vol. 107, no. 2, pp. 637-642, 2006.
    • (2006) Blood , vol.107 , Issue.2 , pp. 637-642
    • Aslam, R.1    Speck, E.R.2    Kim, M.3
  • 43
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
    • J. C. Kagan, T. Su, T. Horng, A. Chow, S. Akira, and R. Medzhitov, "TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β," Nature Immunology, vol. 9, no. 4, pp. 361-368, 2008.
    • (2008) Nature Immunology , vol.9 , Issue.4 , pp. 361-368
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5    Medzhitov, R.6
  • 44
  • 45
    • 0034795208 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
    • F. Randow and B. Seed, "Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability," Nature Cell Biology, vol. 3, no. 10, pp. 891-896, 2001.
    • (2001) Nature Cell Biology , vol.3 , Issue.10 , pp. 891-896
    • Randow, F.1    Seed, B.2
  • 46
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
    • J. C. Kagan and R. Medzhitov, "Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling," Cell, vol. 125, pp. 943-955, 2006.
    • (2006) Cell , vol.125 , pp. 943-955
    • Kagan, J.C.1    Medzhitov, R.2
  • 47
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88:IRAK4:IRAK2 complex in TLR/IL-1R signalling
    • S. C. Lin, Y. C. Lo, and H. Wu, "Helical assembly in the MyD88:IRAK4:IRAK2 complex in TLR/IL-1R signalling," Nature, vol. 465, no. 7300, pp. 885-890, 2010.
    • (2010) Nature , vol.465 , Issue.7300 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 48
    • 79959630000 scopus 로고    scopus 로고
    • Expanding TRAF function: TRAF3 as a tri-faced immune regulator
    • H. Hacker, P. H. Tseng, and M. Karin, "Expanding TRAF function: TRAF3 as a tri-faced immune regulator," Nature Reviews Immunology, vol. 11, no. 7, pp. 457-468, 2011.
    • (2011) Nature Reviews Immunology , vol.11 , Issue.7 , pp. 457-468
    • Hacker, H.1    Tseng, P.H.2    Karin, M.3
  • 50
    • 84991511890 scopus 로고    scopus 로고
    • Biased signalling is an essential feature of TLR4 in glioma cells
    • M. T. Zeuner, C. L. Kruger, K. Volk et al., "Biased signalling is an essential feature of TLR4 in glioma cells," Biochimica et Biophysica Acta, vol. 1863, no. 12, pp. 3084-3095, 2016.
    • (2016) Biochimica et Biophysica Acta , vol.1863 , Issue.12 , pp. 3084-3095
    • Zeuner, M.T.1    Kruger, C.L.2    Volk, K.3
  • 51
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-kB by Toll-like receptors
    • T. Kawai and S. Akira, "Signaling to NF-kB by Toll-like receptors," Trends in Molecular Medicine, vol. 13, no. 11, pp. 460-469, 2007.
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.11 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 52
    • 33644508366 scopus 로고    scopus 로고
    • Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
    • H. Husebye, \O. Halaas, H. Stenmark et al., "Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity," The EMBO Journal, vol. 25, no. 4, pp. 683-692, 2006.
    • (2006) The EMBO Journal , vol.25 , Issue.4 , pp. 683-692
    • Husebye, H.1    Halaas, O.2    Stenmark, H.3
  • 54
    • 0037033073 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Tolllike receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
    • E. Latz, A. Visintin, E. Lien et al., "Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Tolllike receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction," Journal of Biological Chemistry, vol. 277, no. 49, pp. 47834-47843, 2002.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.49 , pp. 47834-47843
    • Latz, E.1    Visintin, A.2    Lien, E.3
  • 55
    • 81055129630 scopus 로고    scopus 로고
    • CD14 controls the LPS-induced endocytosis of Toll-like receptor 4
    • I. Zanoni, R. Ostuni, L. R. Marek et al., "CD14 controls the LPS-induced endocytosis of Toll-like receptor 4," Cell, vol. 147, no. 4, pp. 868-880, 2011.
    • (2011) Cell , vol.147 , Issue.4 , pp. 868-880
    • Zanoni, I.1    Ostuni, R.2    Marek, L.R.3
  • 56
    • 20644469429 scopus 로고    scopus 로고
    • CD14 is required for MyD88-independent LPS signaling
    • Z. Jiang, P. Georgel, X. Du et al., "CD14 is required for MyD88-independent LPS signaling," Nature Immunology, vol. 6, no. 6, pp. 565-570, 2005.
    • (2005) Nature Immunology , vol.6 , Issue.6 , pp. 565-570
    • Jiang, Z.1    Georgel, P.2    Du, X.3
  • 57
    • 84900871178 scopus 로고    scopus 로고
    • Platelet TLR4: A critical link in pulmonary arterial hypertension
    • Z. Sun, "Platelet TLR4: A critical link in pulmonary arterial hypertension," Circulation Research, vol. 114, no. 10, pp. 1551-1553, 2014.
    • (2014) Circulation Research , vol.114 , Issue.10 , pp. 1551-1553
    • Sun, Z.1
  • 58
    • 84927098046 scopus 로고    scopus 로고
    • Platelets are not just for clots
    • J. D. McFadyen and Z. S. Kaplan, "Platelets are not just for clots," Transfusion Medicine Reviews, vol. 29, no. 2, pp. 110-119, 2015.
    • (2015) Transfusion Medicine Reviews , vol.29 , Issue.2 , pp. 110-119
    • McFadyen, J.D.1    Kaplan, Z.S.2
  • 59
    • 4444260266 scopus 로고    scopus 로고
    • Platelet adhesion signalling and the regulation of thrombus formation
    • J. M. Gibbins, "Platelet adhesion signalling and the regulation of thrombus formation," Journal of Cell Science, vol. 117, no. 16, pp. 3415-3425, 2004.
    • (2004) Journal of Cell Science , vol.117 , Issue.16 , pp. 3415-3425
    • Gibbins, J.M.1
  • 61
    • 67649204120 scopus 로고    scopus 로고
    • LPS stimulates platelet secretion and potentiates platelet aggregation via TLR4/ MyD88 and the cGMP-dependent protein kinase pathway
    • G. Zhang, J. Han, E. J. Welch et al., "LPS stimulates platelet secretion and potentiates platelet aggregation via TLR4/ MyD88 and the cGMP-dependent protein kinase pathway," The Journal of Immunology, vol. 182, no. 12, pp. 7997-8004, 2009.
    • (2009) The Journal of Immunology , vol.182 , Issue.12 , pp. 7997-8004
    • Zhang, G.1    Han, J.2    Welch, E.J.3
  • 62
    • 68249146095 scopus 로고    scopus 로고
    • Aggregation and microparticle production through Toll-like receptor 4 activation in platelets from recently menopausal women
    • K. Hashimoto, M. Jayachandran, W. G. Owen, and V. M. Miller, "Aggregation and microparticle production through Toll-like receptor 4 activation in platelets from recently menopausal women," Journal of Cardiovascular Pharmacology, vol. 54, no. 1, pp. 57-62, 2009.
    • (2009) Journal of Cardiovascular Pharmacology , vol.54 , Issue.1 , pp. 57-62
    • Hashimoto, K.1    Jayachandran, M.2    Owen, W.G.3    Miller, V.M.4
  • 64
    • 0037092645 scopus 로고    scopus 로고
    • Demonstration of an activation regulated NF-kappaB/I-kappaBalpha complex in human platelets
    • F. Liu, S. A. Morris, J. L. Epps, and R. C. Carroll, "Demonstration of an activation regulated NF-kappaB/I-kappaBalpha complex in human platelets," Thrombosis Research, vol. 106, no. 4-5, pp. 199-203, 2002.
    • (2002) Thrombosis Research , vol.106 , Issue.4-5 , pp. 199-203
    • Liu, F.1    Morris, S.A.2    Epps, J.L.3    Carroll, R.C.4
  • 65
    • 79955534720 scopus 로고    scopus 로고
    • Lipopolysaccharide signaling without a nucleus: Kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles
    • G. T. Brown and T. M. McIntyre, "Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles," The Journal of Immunology, vol. 186, no. 9, pp. 5489-5496, 2011.
    • (2011) The Journal of Immunology , vol.186 , Issue.9 , pp. 5489-5496
    • Brown, G.T.1    McIntyre, T.M.2
  • 66
    • 84867800826 scopus 로고    scopus 로고
    • Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion
    • J. Berthet, P. Damien, H. Hamzeh-Cognasse et al., "Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion," Clinical Immunology, vol. 145, no. 3, pp. 189-200, 2012.
    • (2012) Clinical Immunology , vol.145 , Issue.3 , pp. 189-200
    • Berthet, J.1    Damien, P.2    Hamzeh-Cognasse, H.3
  • 67
    • 84924054221 scopus 로고    scopus 로고
    • LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-ligand
    • P. Damien, F. Cognasse, M.-A. Eyraud et al., "LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-ligand," BMC Immunology, vol. 16, p. 3, 2015.
    • (2015) BMC Immunology , vol.16 , pp. 3
    • Damien, P.1    Cognasse, F.2    Eyraud, M.-A.3
  • 68
    • 33846885217 scopus 로고    scopus 로고
    • Lipopolysaccharide induces sCD40L release through human platelets TLR4, but not TLR2 and TLR9
    • F. Cognasse, S. Lafarge, P. Chavarin, S. Acquart, and O. Garraud, "Lipopolysaccharide induces sCD40L release through human platelets TLR4, but not TLR2 and TLR9," Intensive Care Medicine, vol. 33, no. 2, pp. 382-384, 2007.
    • (2007) Intensive Care Medicine , vol.33 , Issue.2 , pp. 382-384
    • Cognasse, F.1    Lafarge, S.2    Chavarin, P.3    Acquart, S.4    Garraud, O.5
  • 69
    • 84865241312 scopus 로고    scopus 로고
    • Periodontopathogens induce expression of CD40L on human platelets via TLR2 and TLR4
    • A. Assinger, M. Laky, S. Badrnya, A. Esfandeyari, and I. Volf, "Periodontopathogens induce expression of CD40L on human platelets via TLR2 and TLR4," Thrombosis Research, vol. 130, no. 3, pp. e73-e78, 2012.
    • (2012) Thrombosis Research , vol.130 , Issue.3 , pp. e73-e78
    • Assinger, A.1    Laky, M.2    Badrnya, S.3    Esfandeyari, A.4    Volf, I.5
  • 70
    • 0037143597 scopus 로고    scopus 로고
    • Platelet-derived CD40L: The switch-hitting player of cardiovascular disease
    • P. André, L. Nannizzi-Alaimo, S. K. Prasad, and D. R. Phillips, "Platelet-derived CD40L: the switch-hitting player of cardiovascular disease," Circulation, vol. 106, no. 8, pp. 896-899, 2002.
    • (2002) Circulation , vol.106 , Issue.8 , pp. 896-899
    • André, P.1    Nannizzi-Alaimo, L.2    Prasad, S.K.3    Phillips, D.R.4
  • 71
    • 84940899801 scopus 로고    scopus 로고
    • The role of platelet MyD88 in host response during gram-negative sepsis
    • S. F. de Stoppelaar, T. A. Claushuis, M. P. Jansen et al., "The role of platelet MyD88 in host response during gram-negative sepsis," Journal of Thrombosis and Haemostasis, vol. 13, no. 9, pp. 1709-1720, 2015.
    • (2015) Journal of Thrombosis and Haemostasis , vol.13 , Issue.9 , pp. 1709-1720
    • De Stoppelaar, S.F.1    Claushuis, T.A.2    Jansen, M.P.3
  • 72
    • 23744515307 scopus 로고    scopus 로고
    • Escaping the nuclear confines: Signal-dependent pre-mRNA splicing in anucleate platelets
    • M. M. Denis, N. D. Tolley, M. Bunting et al., "Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets," Cell, vol. 122, pp. 379-391, 2005.
    • (2005) Cell , vol.122 , pp. 379-391
    • Denis, M.M.1    Tolley, N.D.2    Bunting, M.3
  • 73
    • 84880801800 scopus 로고    scopus 로고
    • IkB kinase phosphorylation of SNAP-23 controls platelet secretion
    • Z. A. Karim, J. Zhang, M. Banerjee et al., "IkB kinase phosphorylation of SNAP-23 controls platelet secretion," Blood, vol. 121, no. 22, pp. 4567-4574, 2013.
    • (2013) Blood , vol.121 , Issue.22 , pp. 4567-4574
    • Karim, Z.A.1    Zhang, J.2    Banerjee, M.3
  • 75
    • 0037428145 scopus 로고    scopus 로고
    • A stimulatory role for cGMPdependent protein kinase in platelet activation
    • Z. Li, X. Xi, M. Gu et al., "A stimulatory role for cGMPdependent protein kinase in platelet activation," Cell, vol. 112, no. 1, pp. 77-86, 2003.
    • (2003) Cell , vol.112 , Issue.1 , pp. 77-86
    • Li, Z.1    Xi, X.2    Gu, M.3
  • 76
    • 5644249326 scopus 로고    scopus 로고
    • A platelet secretion pathway mediated by cGMP-dependent protein kinase
    • Z. Li, G. Zhang, J. A. Marjanovic, C. Ruan, and X. Du, "A platelet secretion pathway mediated by cGMP-dependent protein kinase," Journal of Biological Chemistry, vol. 279, no. 41, pp. 42469-42475, 2004.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.41 , pp. 42469-42475
    • Li, Z.1    Zhang, G.2    Marjanovic, J.A.3    Ruan, C.4    Du, X.5
  • 77
    • 27144467146 scopus 로고    scopus 로고
    • Agonists of Toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor
    • J. R. Ward, L. Bingle, H. M. Judge et al., "Agonists of Toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor," Thrombosis and Haemostasis, vol. 94, no. 4, pp. 831-838, 2005.
    • (2005) Thrombosis and Haemostasis , vol.94 , Issue.4 , pp. 831-838
    • Ward, J.R.1    Bingle, L.2    Judge, H.M.3
  • 78
    • 84973632359 scopus 로고    scopus 로고
    • Toll-like receptor signalling is not involved in platelet response to Streptococcus pneumoniae in vitro or in vivo
    • S. F. de Stoppelaar, T. A. M. Claushuis, M. C. Schaap et al., "Toll-like receptor signalling is not involved in platelet response to Streptococcus pneumoniae in vitro or in vivo," PLoS One, vol. 11, no. 6, article e0156977, 2016.
    • (2016) PLoS One , vol.11 , Issue.6
    • De Stoppelaar, S.F.1    Claushuis, T.A.M.2    Schaap, M.C.3
  • 81
    • 80051884192 scopus 로고    scopus 로고
    • Extracellular histones promote thrombin generation through platelet-dependent mechanisms: Involvement of platelet TLR2 and TLR4
    • F. Semeraro, C. T. Ammollo, J. H. Morrissey et al., "Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4," Blood, vol. 118, no. 7, pp. 1952-1961, 2011.
    • (2011) Blood , vol.118 , Issue.7 , pp. 1952-1961
    • Semeraro, F.1    Ammollo, C.T.2    Morrissey, J.H.3
  • 82
    • 85027244902 scopus 로고    scopus 로고
    • Development and characterisation of a novel NF-kB reporter cell line for investigation of neuroinflammation
    • M. Zeuner, T. Vallance, S. Vaiyapuri, G. S. Cottrell, and D. Widera, "Development and characterisation of a novel NF-kB reporter cell line for investigation of neuroinflammation," Mediators of Inflammation, vol. 2017, Article ID 6209865, 2017.
    • (2017) Mediators of Inflammation , vol.2017
    • Zeuner, M.1    Vallance, T.2    Vaiyapuri, S.3    Cottrell, G.S.4    Widera, D.5
  • 83
    • 83455182149 scopus 로고    scopus 로고
    • Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout
    • I. Mitroulis, K. Kambas, A. Chrysanthopoulou et al., "Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout," PLoS One, vol. 6, no. 12, article e29318, 2011.
    • (2011) PLoS One , vol.6 , Issue.12
    • Mitroulis, I.1    Kambas, K.2    Chrysanthopoulou, A.3
  • 84
    • 84923381173 scopus 로고    scopus 로고
    • Platelets promote tumour metastasis via interaction between TLR4 and tumour cellreleased high-mobility group box1 protein
    • L. X. Yu, L. Yan, W. Yang et al., "Platelets promote tumour metastasis via interaction between TLR4 and tumour cellreleased high-mobility group box1 protein," Nature Communications, vol. 5, p. 5256, 2014.
    • (2014) Nature Communications , vol.5 , pp. 5256
    • Yu, L.X.1    Yan, L.2    Yang, W.3
  • 85
    • 79251478398 scopus 로고    scopus 로고
    • Contribution of platelets to tumour metastasis
    • L. J. Gay and B. Felding-Habermann, "Contribution of platelets to tumour metastasis," Nature Reviews Cancer, vol. 11, no. 2, pp. 123-134, 2011.
    • (2011) Nature Reviews Cancer , vol.11 , Issue.2 , pp. 123-134
    • Gay, L.J.1    Felding-Habermann, B.2
  • 86
    • 70149098507 scopus 로고    scopus 로고
    • The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
    • H. Hreggvidsdottir, T. Ostberg, H. Wähämaa et al., "The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation," Journal of Leukocyte Biology, vol. 86, no. 3, pp. 655-662, 2009.
    • (2009) Journal of Leukocyte Biology , vol.86 , Issue.3 , pp. 655-662
    • Hreggvidsdottir, H.1    Ostberg, T.2    Wähämaa, H.3
  • 87
    • 44449162626 scopus 로고    scopus 로고
    • High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-α production in human monocytes
    • J. H. Youn, Y. J. Oh, E. S. Kim, J. E. Choi, and J. Shin, "High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-α production in human monocytes," The Journal of Immunology, vol. 180, no. 7, pp. 5067-5074, 2008.
    • (2008) The Journal of Immunology , vol.180 , Issue.7 , pp. 5067-5074
    • Youn, J.H.1    Oh, Y.J.2    Kim, E.S.3    Choi, J.E.4    Shin, J.5
  • 89
    • 84953327772 scopus 로고    scopus 로고
    • Extracellular histones induce chemokine production in whole blood ex vivo and leukocyte recruitment in vivo
    • J. Westman, P. Papareddy, M. W. Dahlgren et al., "Extracellular histones induce chemokine production in whole blood ex vivo and leukocyte recruitment in vivo," PLoS Pathogens, vol. 11, no. 12, article e1005319, 2015.
    • (2015) PLoS Pathogens , vol.11 , Issue.12
    • Westman, J.1    Papareddy, P.2    Dahlgren, M.W.3
  • 90
    • 80051882006 scopus 로고    scopus 로고
    • Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
    • J. Xu, X. Zhang, M. Monestier, N. L. Esmon, and C. T. Esmon, "Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury," The Journal of Immunology, vol. 187, no. 5, pp. 2626-2631, 2011.
    • (2011) The Journal of Immunology , vol.187 , Issue.5 , pp. 2626-2631
    • Xu, J.1    Zhang, X.2    Monestier, M.3    Esmon, N.L.4    Esmon, C.T.5
  • 91
    • 70449107044 scopus 로고    scopus 로고
    • Extracellular histones are major mediators of death in sepsis
    • J. Xu, X. Zhang, R. Pelayo et al., "Extracellular histones are major mediators of death in sepsis," Nature Medicine, vol. 15, no. 11, pp. 1318-1321, 2009.
    • (2009) Nature Medicine , vol.15 , Issue.11 , pp. 1318-1321
    • Xu, J.1    Zhang, X.2    Pelayo, R.3
  • 92
    • 80053362674 scopus 로고    scopus 로고
    • Extracellular histones zap platelets
    • C. T. Esmon, "Extracellular histones zap platelets," Blood, vol. 118, no. 13, pp. 3456-3457, 2011.
    • (2011) Blood , vol.118 , Issue.13 , pp. 3456-3457
    • Esmon, C.T.1
  • 93
    • 80053354116 scopus 로고    scopus 로고
    • Histones induce rapid and profound thrombocytopenia in mice
    • T. A. Fuchs, A. A. Bhandari, and D. D. Wagner, "Histones induce rapid and profound thrombocytopenia in mice," Blood, vol. 118, no. 13, pp. 3708-3714, 2011.
    • (2011) Blood , vol.118 , Issue.13 , pp. 3708-3714
    • Fuchs, T.A.1    Bhandari, A.A.2    Wagner, D.D.3
  • 94
    • 84945185080 scopus 로고    scopus 로고
    • Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation
    • Y. Zhao, C. Zhang, X. Wei et al., "Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation," Scientific Reports, vol. 5, no. 1, article 15352, 2015.
    • (2015) Scientific Reports , vol.5 , Issue.1
    • Zhao, Y.1    Zhang, C.2    Wei, X.3
  • 95
    • 0034016294 scopus 로고    scopus 로고
    • Fluid shear stress induces heat shock protein 60 expression in endothelial cells in vitro and in vivo
    • B. Hochleitner, E. Hochleitner, P. Obrist et al., "Fluid shear stress induces heat shock protein 60 expression in endothelial cells in vitro and in vivo," Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, pp. 617-623, 2000.
    • (2000) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.20 , pp. 617-623
    • Hochleitner, B.1    Hochleitner, E.2    Obrist, P.3
  • 96
    • 84933052018 scopus 로고    scopus 로고
    • Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via Toll-like receptor 4 in mesenchymal stem cells
    • R. Ebert, P. Benisch, M. Krug et al., "Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via Toll-like receptor 4 in mesenchymal stem cells," Stem Cell Research, vol. 15, no. 1, pp. 231-239, 2015.
    • (2015) Stem Cell Research , vol.15 , Issue.1 , pp. 231-239
    • Ebert, R.1    Benisch, P.2    Krug, M.3
  • 98
    • 84900867405 scopus 로고    scopus 로고
    • Genetic deletion of Toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension
    • E. M. Bauer, R. S. Chanthaphavong, C. P. Sodhi, D. J. Hackam, T. R. Billiar, and P. M. Bauer, "Genetic deletion of Toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension," Circulation Research, vol. 114, no. 10, pp. 1596-1600, 2014.
    • (2014) Circulation Research , vol.114 , Issue.10 , pp. 1596-1600
    • Bauer, E.M.1    Chanthaphavong, R.S.2    Sodhi, C.P.3    Hackam, D.J.4    Billiar, T.R.5    Bauer, P.M.6
  • 99
    • 84925874073 scopus 로고    scopus 로고
    • TLR4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation
    • N. Ding, G. Chen, R. Hoffman et al., "TLR4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation," Circulation: Cardiovascular Genetics, vol. 7, no. 5, pp. 615-624, 2014.
    • (2014) Circulation: Cardiovascular Genetics , vol.7 , Issue.5 , pp. 615-624
    • Ding, N.1    Chen, G.2    Hoffman, R.3
  • 100
    • 33646408749 scopus 로고    scopus 로고
    • Reduced thromboxane biosynthesis in carriers of Toll-like receptor 4 polymorphisms in vivo
    • P. Patrignani, C. Di Febbo, S. Tacconelli et al., "Reduced thromboxane biosynthesis in carriers of Toll-like receptor 4 polymorphisms in vivo," Blood, vol. 107, no. 9, pp. 3572-3574, 2006.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3572-3574
    • Patrignani, P.1    Di Febbo, C.2    Tacconelli, S.3
  • 101
    • 84932142768 scopus 로고    scopus 로고
    • Calpain activity and Toll-like receptor 4 expression in platelet regulate haemostatic situation in patients undergoing cardiac surgery and coagulation in mice
    • J. C. Tsai, Y. W. Lin, C. Y. Huang, F. Y. Lin, and C. S. Tsai, "Calpain activity and Toll-like receptor 4 expression in platelet regulate haemostatic situation in patients undergoing cardiac surgery and coagulation in mice," Mediators of Inflammation, vol. 2014, Article ID 484510, 12 pages, 2014.
    • (2014) Mediators of Inflammation , vol.2014
    • Tsai, J.C.1    Lin, Y.W.2    Huang, C.Y.3    Lin, F.Y.4    Tsai, C.S.5


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