Endotoxin•albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Innate Immunity

Volumn 18, Issue 3, 2012, Pages 478-491

  Esparza, Gregory A ^a,b   Teghanemt, Athmane ^b   Zhang, Desheng ^b   Gioannini, Theresa L ^b,c   Weiss, Jerrold P ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Albumin; CD14; endotoxin; MD 2; Toll like receptor 4

Indexed keywords

ALBUMIN; CALCIUM; CD14 ANTIGEN; ENDOTOXIN; MAGNESIUM; MONOMER; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; ALBUMINOID; MULTIPROTEIN COMPLEX;

ARTICLE; CELL ACTIVATION; EXTRACTION; HUMAN; HUMAN CELL; INCUBATION TIME; MOLECULAR RECOGNITION; PURIFICATION; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; GRAM POSITIVE INFECTION; HOST PATHOGEN INTERACTION; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE; MOUSE MUTANT; POLYMERIZATION; PROTEIN ENGINEERING; PROTEIN TRANSPORT;

NEGIBACTERIA;

ALBUMINS; ANIMALS; ANTIGENS, CD14; CELL LINE; ENDOTOXINS; GRAM-POSITIVE BACTERIAL INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; LYMPHOCYTE ANTIGEN 96; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; POLYMERIZATION; PROTEIN ENGINEERING; PROTEIN TRANSPORT; TOLL-LIKE RECEPTOR 4;

EID: 84860879114     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425911422723     Document Type: Article

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