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Volumn 129, Issue 3, 2014, Pages 448-462

LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes

Author keywords

alcohol; innate immune response; internalization; TLR4 signalling

Indexed keywords

ALCOHOL; INNATE IMMUNE RESPONSE; INTERNALIZATION; TLR4 SIGNALLING;

EID: 84899461458     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12639     Document Type: Article
Times cited : (70)

References (58)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., and, Takeda K., (2004) Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 2
    • 84867713025 scopus 로고    scopus 로고
    • The p110delta isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
    • Aksoy E., Taboubi S., Torres D., et al,. (2012) The p110delta isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat. Immunol. 13, 1045-1054.
    • (2012) Nat. Immunol. , vol.13 , pp. 1045-1054
    • Aksoy, E.1    Taboubi, S.2    Torres, D.3
  • 6
    • 59849109889 scopus 로고    scopus 로고
    • Green fluorescent protein based pH indicators for in vivo use: A review
    • Bizzarri R., Serresi M., Luin S., and, Beltram F., (2009) Green fluorescent protein based pH indicators for in vivo use: a review. Anal. Bioanal. Chem. 393, 1107-1122.
    • (2009) Anal. Bioanal. Chem. , vol.393 , pp. 1107-1122
    • Bizzarri, R.1    Serresi, M.2    Luin, S.3    Beltram, F.4
  • 7
    • 1842451736 scopus 로고    scopus 로고
    • Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-kappa B
    • Blanco A. M., Pascual M., Valles S. L., and, Guerri C., (2004) Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-kappa B. NeuroReport 15, 681-685.
    • (2004) NeuroReport , vol.15 , pp. 681-685
    • Blanco, A.M.1    Pascual, M.2    Valles, S.L.3    Guerri, C.4
  • 8
    • 27744562724 scopus 로고    scopus 로고
    • Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes
    • Blanco A. M., Valles S. L., Pascual M., and, Guerri C., (2005) Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. J. Immunol. 175, 6893-6899.
    • (2005) J. Immunol. , vol.175 , pp. 6893-6899
    • Blanco, A.M.1    Valles, S.L.2    Pascual, M.3    Guerri, C.4
  • 9
    • 51649111509 scopus 로고    scopus 로고
    • Ethanol mimics ligand-mediated activation and endocytosis of IL-1RI/TLR4 receptors via lipid rafts caveolae in astroglial cells
    • Blanco A. M., Perez-Arago A., Fernandez-Lizarbe S., and, Guerri C., (2008) Ethanol mimics ligand-mediated activation and endocytosis of IL-1RI/TLR4 receptors via lipid rafts caveolae in astroglial cells. J. Neurochem. 106, 625-639.
    • (2008) J. Neurochem. , vol.106 , pp. 625-639
    • Blanco, A.M.1    Perez-Arago, A.2    Fernandez-Lizarbe, S.3    Guerri, C.4
  • 10
    • 0036565888 scopus 로고    scopus 로고
    • Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: A molecular basis for priming and synergism with bacterial lipopolysaccharide
    • Bosisio D., Polentarutti N., Sironi M., Bernasconi S., Miyake K., Webb G. R., Martin M. U., Mantovani A., and, Muzio M., (2002) Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 99, 3427-3431.
    • (2002) Blood , vol.99 , pp. 3427-3431
    • Bosisio, D.1    Polentarutti, N.2    Sironi, M.3    Bernasconi, S.4    Miyake, K.5    Webb, G.R.6    Martin, M.U.7    Mantovani, A.8    Muzio, M.9
  • 11
    • 0042377367 scopus 로고    scopus 로고
    • Cultured astrocytes express toll-like receptors for bacterial products
    • Bowman C. C., Rasley A., Tranguch S. L., and, Marriott I., (2003) Cultured astrocytes express toll-like receptors for bacterial products. Glia 43, 281-291.
    • (2003) Glia , vol.43 , pp. 281-291
    • Bowman, C.C.1    Rasley, A.2    Tranguch, S.L.3    Marriott, I.4
  • 13
    • 13544272944 scopus 로고    scopus 로고
    • Differential activation of astrocytes by innate and adaptive immune stimuli
    • Carpentier P. A., Begolka W. S., Olson J. K., Elhofy A., Karpus W. J., and, Miller S. D., (2005) Differential activation of astrocytes by innate and adaptive immune stimuli. Glia 49, 360-374.
    • (2005) Glia , vol.49 , pp. 360-374
    • Carpentier, P.A.1    Begolka, W.S.2    Olson, J.K.3    Elhofy, A.4    Karpus, W.J.5    Miller, S.D.6
  • 14
    • 33645292025 scopus 로고    scopus 로고
    • Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids
    • Cheng Z. J., Singh R. D., Marks D. L., and, Pagano R. E., (2006) Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids. Mol. Membr. Biol. 23, 101-110.
    • (2006) Mol. Membr. Biol. , vol.23 , pp. 101-110
    • Cheng, Z.J.1    Singh, R.D.2    Marks, D.L.3    Pagano, R.E.4
  • 15
    • 80053307621 scopus 로고    scopus 로고
    • Toll-like receptor expression and activation in astroglia: Differential regulation by HIV-1 Tat, gp120, and morphine
    • El-Hage N., Podhaizer E. M., Sturgill J., and, Hauser K. F., (2011) Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine. Immunol. Invest. 40, 498-522.
    • (2011) Immunol. Invest. , vol.40 , pp. 498-522
    • El-Hage, N.1    Podhaizer, E.M.2    Sturgill, J.3    Hauser, K.F.4
  • 16
    • 0942287664 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus
    • Esen N., Tanga F. Y., DeLeo J. A., and, Kielian T., (2004) Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. J. Neurochem. 88, 746-758.
    • (2004) J. Neurochem. , vol.88 , pp. 746-758
    • Esen, N.1    Tanga, F.Y.2    Deleo, J.A.3    Kielian, T.4
  • 17
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina C., Aloisi F., and, Meinl E., (2007) Astrocytes are active players in cerebral innate immunity. Trends Immunol. 28, 138-145.
    • (2007) Trends Immunol. , vol.28 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 18
    • 71649086146 scopus 로고    scopus 로고
    • Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits
    • Ferguson S. M., Raimondi A., Paradise S., et al,. (2009) Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev. Cell 17, 811-822.
    • (2009) Dev. Cell , vol.17 , pp. 811-822
    • Ferguson, S.M.1    Raimondi, A.2    Paradise, S.3
  • 19
    • 38949188640 scopus 로고    scopus 로고
    • Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages
    • Fernandez-Lizarbe S., Pascual M., Gascon M. S., Blanco A., and, Guerri C., (2008) Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages. Mol. Immunol. 45, 2007-2016.
    • (2008) Mol. Immunol. , vol.45 , pp. 2007-2016
    • Fernandez-Lizarbe, S.1    Pascual, M.2    Gascon, M.S.3    Blanco, A.4    Guerri, C.5
  • 20
    • 70449732755 scopus 로고    scopus 로고
    • Critical role of TLR4 response in the activation of microglia induced by ethanol
    • Fernandez-Lizarbe S., Pascual M., and, Guerri C., (2009) Critical role of TLR4 response in the activation of microglia induced by ethanol. J. Immunol. 183, 4733-4744.
    • (2009) J. Immunol. , vol.183 , pp. 4733-4744
    • Fernandez-Lizarbe, S.1    Pascual, M.2    Guerri, C.3
  • 21
    • 84879992339 scopus 로고    scopus 로고
    • Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells
    • Fernandez-Lizarbe S., Montesinos J., and, Guerri C., (2013) Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells. J. Neurochem. 126, 261-273.
    • (2013) J. Neurochem. , vol.126 , pp. 261-273
    • Fernandez-Lizarbe, S.1    Montesinos, J.2    Guerri, C.3
  • 22
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass C. K., Saijo K., Winner B., Marchetto M. C., and, Gage F. H., (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934.
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 23
    • 0242516021 scopus 로고    scopus 로고
    • RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol
    • Guasch R. M., Tomas M., Minambres R., Valles S., Renau-Piqueras J., and, Guerri C., (2003) RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol. J. Neurosci. Res. 72, 487-502.
    • (2003) J. Neurosci. Res. , vol.72 , pp. 487-502
    • Guasch, R.M.1    Tomas, M.2    Minambres, R.3    Valles, S.4    Renau-Piqueras, J.5    Guerri, C.6
  • 27
    • 0032506222 scopus 로고    scopus 로고
    • Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy
    • Haupts U., Maiti S., Schwille P., and, Webb W. W., (1998) Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy. Proc. Natl Acad. Sci. USA 95, 13573-13578.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 13573-13578
    • Haupts, U.1    Maiti, S.2    Schwille, P.3    Webb, W.W.4
  • 28
    • 0034526495 scopus 로고    scopus 로고
    • Dynamin and its role in membrane fission
    • Hinshaw J. E., (2000) Dynamin and its role in membrane fission. Annu. Rev. Cell Dev. Biol. 16, 483-519.
    • (2000) Annu. Rev. Cell Dev. Biol. , vol.16 , pp. 483-519
    • Hinshaw, J.E.1
  • 29
    • 84856739147 scopus 로고    scopus 로고
    • Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response
    • Holm T. H., Draeby D., and, Owens T., (2012) Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response. Glia 60, 630-638.
    • (2012) Glia , vol.60 , pp. 630-638
    • Holm, T.H.1    Draeby, D.2    Owens, T.3
  • 31
    • 84934436076 scopus 로고    scopus 로고
    • Pharmacological inhibition of endocytic pathways: Is it specific enough to be useful?
    • Ivanov A. I., (2008) Pharmacological inhibition of endocytic pathways: is it specific enough to be useful? Methods Mol. Biol. 440, 15-33.
    • (2008) Methods Mol. Biol. , vol.440 , pp. 15-33
    • Ivanov, A.I.1
  • 32
    • 0027764386 scopus 로고
    • Endosome acidification and receptor trafficking: Bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif
    • Johnson L. S., Dunn K. W., Pytowski B., and, McGraw T. E., (1993) Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif. Mol. Biol. Cell 4, 1251-1266.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1251-1266
    • Johnson, L.S.1    Dunn, K.W.2    Pytowski, B.3    McGraw, T.E.4
  • 33
    • 0035124052 scopus 로고    scopus 로고
    • Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting
    • Jover R., Bort R., Gomez-Lechon M. J., and, Castell J. V., (2001) Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting. Hepatology 33, 668-675.
    • (2001) Hepatology , vol.33 , pp. 668-675
    • Jover, R.1    Bort, R.2    Gomez-Lechon, M.J.3    Castell, J.V.4
  • 34
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
    • Kagan J. C., Su T., Horng T., Chow A., Akira S., and, Medzhitov R., (2008) TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat. Immunol. 9, 361-368.
    • (2008) Nat. Immunol. , vol.9 , pp. 361-368
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5    Medzhitov, R.6
  • 35
    • 0031885535 scopus 로고    scopus 로고
    • Green fluorescent protein as a noninvasive intracellular pH indicator
    • Kneen M., Farinas J., Li Y., and, Verkman A. S., (1998) Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys. J. 74, 1591-1599.
    • (1998) Biophys. J. , vol.74 , pp. 1591-1599
    • Kneen, M.1    Farinas, J.2    Li, Y.3    Verkman, A.S.4
  • 36
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy C., and, Wrana J. L., (2005) Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat. Rev. Mol. Cell Biol. 6, 112-126.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 38
    • 77249160271 scopus 로고    scopus 로고
    • Localisation and trafficking of Toll-like receptors: An important mode of regulation
    • McGettrick A. F., and, O'Neill L. A., (2010) Localisation and trafficking of Toll-like receptors: an important mode of regulation. Curr. Opin. Immunol. 22, 20-27.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 20-27
    • McGettrick, A.F.1    O'Neill, L.A.2
  • 39
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • Medvedev A. E., Kopydlowski K. M., and, Vogel S. N., (2000) Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J. Immunol. 164, 5564-5574.
    • (2000) J. Immunol. , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 41
    • 32244433301 scopus 로고    scopus 로고
    • The RhoA/ROCK-I/MLC pathway is involved in the ethanol-induced apoptosis by anoikis in astrocytes
    • Minambres R., Guasch R. M., Perez-Arago A., and, Guerri C., (2006) The RhoA/ROCK-I/MLC pathway is involved in the ethanol-induced apoptosis by anoikis in astrocytes. J. Cell Sci. 119, 271-282.
    • (2006) J. Cell Sci. , vol.119 , pp. 271-282
    • Minambres, R.1    Guasch, R.M.2    Perez-Arago, A.3    Guerri, C.4
  • 43
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression
    • Nomura F., Akashi S., Sakao Y., et al,. (2000) Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J. Immunol. 164, 3476-3479.
    • (2000) J. Immunol. , vol.164 , pp. 3476-3479
    • Nomura, F.1    Akashi, S.2    Sakao, Y.3
  • 44
    • 0031750101 scopus 로고    scopus 로고
    • Filipin-dependent inhibition of cholera toxin: Evidence for toxin internalization and activation through caveolae-like domains
    • Orlandi P. A., and, Fishman P. H., (1998) Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol. 141, 905-915.
    • (1998) J. Cell Biol. , vol.141 , pp. 905-915
    • Orlandi, P.A.1    Fishman, P.H.2
  • 45
    • 0028130266 scopus 로고
    • Duration of expression of inducible nitric oxide synthase in glial cells
    • Park S. K., and, Murphy S., (1994) Duration of expression of inducible nitric oxide synthase in glial cells. J. Neurosci. Res. 39, 405-411.
    • (1994) J. Neurosci. Res. , vol.39 , pp. 405-411
    • Park, S.K.1    Murphy, S.2
  • 47
    • 44149094808 scopus 로고    scopus 로고
    • ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: Implications in hepatic stress responses
    • Pascual M., Gomez-Lechon M. J., Castell J. V., and, Jover R., (2008) ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses. Drug Metab. Dispos. 36, 1063-1072.
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1063-1072
    • Pascual, M.1    Gomez-Lechon, M.J.2    Castell, J.V.3    Jover, R.4
  • 48
    • 0036239115 scopus 로고    scopus 로고
    • Endocytosis via caveolae
    • Pelkmans L., and, Helenius A., (2002) Endocytosis via caveolae. Traffic 3, 311-320.
    • (2002) Traffic , vol.3 , pp. 311-320
    • Pelkmans, L.1    Helenius, A.2
  • 49
    • 0024541481 scopus 로고
    • Effects of prolonged ethanol exposure on the glial fibrillary acidic protein-containing intermediate filaments of astrocytes in primary culture: A quantitative immunofluorescence and immunogold electron microscopic study
    • Renau-Piqueras J., Zaragoza R., De Paz P., Baguena-Cervellera R., Megias L., and, Guerri C., (1989) Effects of prolonged ethanol exposure on the glial fibrillary acidic protein-containing intermediate filaments of astrocytes in primary culture: a quantitative immunofluorescence and immunogold electron microscopic study. J. Histochem. Cytochem. 37, 229-240.
    • (1989) J. Histochem. Cytochem. , vol.37 , pp. 229-240
    • Renau-Piqueras, J.1    Zaragoza, R.2    De Paz, P.3    Baguena-Cervellera, R.4    Megias, L.5    Guerri, C.6
  • 50
    • 0037111523 scopus 로고    scopus 로고
    • Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages
    • Schilling D., Thomas K., Nixdorff K., Vogel S. N., and, Fenton M. J., (2002) Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages. J. Immunol. 169, 5874-5880.
    • (2002) J. Immunol. , vol.169 , pp. 5874-5880
    • Schilling, D.1    Thomas, K.2    Nixdorff, K.3    Vogel, S.N.4    Fenton, M.J.5
  • 51
    • 0027997787 scopus 로고
    • Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules
    • Schnitzer J. E., Oh P., Pinney E., and, Allard J., (1994) Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J. Cell Biol. 127, 1217-1232.
    • (1994) J. Cell Biol. , vol.127 , pp. 1217-1232
    • Schnitzer, J.E.1    Oh, P.2    Pinney, E.3    Allard, J.4
  • 52
    • 75749096347 scopus 로고    scopus 로고
    • The endocytic matrix
    • Scita G., and, Di Fiore P. P., (2010) The endocytic matrix. Nature 463, 464-473.
    • (2010) Nature , vol.463 , pp. 464-473
    • Scita, G.1    Di Fiore, P.P.2
  • 56
    • 0037096172 scopus 로고    scopus 로고
    • Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
    • Triantafilou M., Miyake K., Golenbock D. T., and, Triantafilou K., (2002) Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J. Cell Sci. 115, 2603-2611.
    • (2002) J. Cell Sci. , vol.115 , pp. 2603-2611
    • Triantafilou, M.1    Miyake, K.2    Golenbock, D.T.3    Triantafilou, K.4
  • 57
    • 0027520440 scopus 로고
    • Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
    • Wang L. H., Rothberg K. G., and, Anderson R. G., (1993) Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J. Cell Biol. 123, 1107-1117.
    • (1993) J. Cell Biol. , vol.123 , pp. 1107-1117
    • Wang, L.H.1    Rothberg, K.G.2    Anderson, R.G.3
  • 58
    • 1842832338 scopus 로고    scopus 로고
    • Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit
    • Yao D., Ehrlich M., Henis Y. I., and, Leof E. B., (2002) Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit. Mol. Biol. Cell 13, 4001-4012.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4001-4012
    • Yao, D.1    Ehrlich, M.2    Henis, Y.I.3    Leof, E.B.4


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