Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion

Clinical Immunology

Volumn 145, Issue 3, 2012, Pages 189-200

  Berthet, Julien ^a   Damien, Pauline ^a   Hamzeh Cognasse, Hind ^a   Arthaud, Charles Antoine ^b   Eyraud, Marie Ange ^b   Zéni, Fabrice ^a,c   Pozzetto, Bruno ^a,c   McNicol, Archibald ^d   Garraud, Olivier ^a,b   Cognasse, Fabrice ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b ETABLISSEMENT FRANÇAIS DU SANG   (France)

^c UNIVERSITY HOSPITAL OF SAINT ETIENNE   (France)

^d UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Cytokine; Inflammation; Lipopolysaccharide; Platelet; Sepsis; TLR TLR4

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL STRAIN; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOMODULATION; INNATE IMMUNITY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; SALMONELLA MINNESOTA; SIGNAL TRANSDUCTION; SUPERNATANT; THROMBOCYTE; THROMBOCYTE RICH PLASMA;

ANTIGENS, CD14; ANTIGENS, CD63; BLOOD PLATELETS; CYTOKINES; ESCHERICHIA COLI; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-6; INTERLEUKIN-8; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; P-SELECTIN; PLATELET ACTIVATION; PROTEIN ISOFORMS; SALMONELLA; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84867800826     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2012.09.004     Document Type: Article

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