Maternal immune activation induced by lipopolysaccharide triggers immune response in pregnant mother and fetus, and induces behavioral impairment in adult rats

Journal of Psychiatric Research

Volumn 100, Issue , 2018, Pages 71-83

  Simões, Lutiana Roque ^a   Sangiogo, Gustavo ^a   Tashiro, Michael Hikaru ^a   Generoso, Jaqueline S ^a   Faller, Cristiano Julio ^a   Dominguini, Diogo ^a   Mastella, Gustavo Antunes ^a   Scaini, Giselli ^b   Giridharan, Vijayasree Vayalanellore ^b   Michels, Monique ^a   Florentino, Drielly ^a   Petronilho, Fabricia ^a   Réus, Gislaine Zilli ^a   Dal Pizzol, Felipe ^a   Zugno, Alexandra I ^a   Barichello, Tatiana ^a,b,c  

^a UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Blood brain barrier; Cytokine; Ketamine; Maternal immune activation; Placental barrier; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CARBONYL DERIVATIVE; CATALASE; COLONY STIMULATING FACTOR 1; GELATINASE A; GELATINASE B; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; KETAMINE; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MALONALDEHYDE; NERVE GROWTH FACTOR; NEUROTROPHIN; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR; AMINO ACID RECEPTOR BLOCKING AGENT; CYTOKINE;

AMNION FLUID; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; BEHAVIOR DISORDER; BLOOD BRAIN BARRIER; BLOOD PLACENTA BARRIER; BRAIN CORTEX; CLINICAL EVALUATION; CONTROLLED STUDY; EXPERIMENTAL TEST; FEMALE; FETUS; FETUS BRAIN; GESTATIONAL AGE; HIPPOCAMPUS; IMMUNE RESPONSE; INNATE IMMUNITY; INTRAUTERINE INFECTION; LOCOMOTION; MALE; MATERNAL IMMUNE ACTIVATION; MEMORY DISORDER; MEMORY TEST; NONHUMAN; OXIDATIVE STRESS; PLACENTA; POSTNATAL CARE; PRE PULSE INHIBITION TEST; PREFRONTAL CORTEX; PREGNANT WOMAN; PRENATAL EXPOSURE; PRENATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCHIZOPHRENIA; WISTAR RAT; ANIMAL; ANIMAL BEHAVIOR; BRAIN; CHEMICALLY INDUCED; DRUG EFFECT; IMMUNOLOGY; INFLAMMATION; MAMMALIAN EMBRYO; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION; PREPULSE INHIBITION;

ANIMALS; BEHAVIOR, ANIMAL; BLOOD-BRAIN BARRIER; BRAIN; CYTOKINES; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; INFLAMMATION; KETAMINE; LIPOPOLYSACCHARIDES; MALE; MEMORY DISORDERS; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS; PREPULSE INHIBITION; RATS; RATS, WISTAR;

EID: 85042464464     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2018.02.007     Document Type: Article

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