Maternal poly I:C exposure during pregnancy regulates TNFα, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat

Journal of Neuroimmunology

Volumn 159, Issue 1-2, 2005, Pages 106-112

  Gilmore, John H ^a   Jarskog, L Fredrik ^a   Vadlamudi, Swarooparani ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Amniotic fluid; Animal model; Cortex; Infection; Placenta; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA;

AMNION FLUID; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS LIVER; INFECTION RISK; MATERNAL PLASMA; MOTHER FETUS RELATIONSHIP; NEUROLOGIC DISEASE; NONHUMAN; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPLEEN; STATISTICAL SIGNIFICANCE;

AMNIOTIC FLUID; ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; DOWN-REGULATION; FEMALE; INJECTIONS, INTRAPERITONEAL; LIVER; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; NERVE GROWTH FACTOR; POLY I-C; PREGNANCY; PREGNANCY PROTEINS; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 12344280393     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.10.008     Document Type: Article

References (39)

1. D.M. Araujo, and C.W. Cotman Differential effects of interleukin-1b and interleukin-2 on glia and hippocampal neurons in culture Int. J. Dev. Neurosci. 13 1995 201 212
2. H.A. Arnett, J. Mason, M. Marino, K. Suzuki, G.K. Matsushima, and J.P.-Y. Ting TNFα promotes proliferation of oligodendrocyte progenitors and remyelination Nat. Neurosci. 4 2001 1116 1122
3. M.J. Bell, J.M. Hallenbeck, and V. Gallo Determining the fetal inflammatory response in an experimental model of intrauterine inflammation in rats Ped. Res. 56 2004 541 546
4. J. Borrell, J.M. Vela, A. Arevalo-Martin, E. Molina-Holgado, and C. Guaza Prenatal immune challenge disrupts sensorimotor gating in adult rats: implications for the etiopathogenesis of schizophrenia Neuropsychopharmacology 26 2002 204 215
5. C.D. Breder, M. Tsujimoto, Y. Terano, D.W. Scott, and C.B. Saper Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system J. Comp. Neurol. 337 1993 543 567
6. A.S. Brown, C.A. Schaefer, R.J. Wyatt, R. Goetz, M.D. Begg, J.M. Gorman, and E.S. Susser Maternal exposure to respiratory infections and adult schizophrenia: a prospective birth cohort study Schizophr. Bull. 26 2000 287 295
7. Z. Cai, Z.L. Pan, Y. Pang, O.B. Evans, and P.G. Rhodes Cytokine induction in fetal brains and brain injury in neonatal rats after maternal lipopolysaccharide administration Pediatr. Res. 47 2000 64 72
8. A.L. Ciaranello, and R.D. Ciaranello The neurobiology of autism Annu. Rev. Neurosci. 18 1995 101 128
9. O. Dammann, and A. Leviton Maternal intrauterine infection, cytokines, and brain damage in the premature infant Pediatr. Res. 42 1997 1 8
10. K. Deguchi, M. Mizuguchi, and S. Takashima Immunohistochemical expression of tumor necrosis factor α in neonatal leukomalacia Pediatr. Neurol. 14 1996 13 16
11. P.L. Fidel, R. Romero, N. Wolf, J. Cutright, M. Ramirez, H. Araneda, and D.B. Cotton Systemic and local cytokine profiles in endotoxin-induced preterm parturition in mice Am. J. Obstet. Gynecol. 170 1994 1467 1475
12. V. Fontaine, S. Mohand-Said, N. Hanoteau, C. Fuchs, K. Pfizenmaier, and U. Eisel Neurodegenerative and neuroprotective effects of tumor necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2 J. Neurosci. 22 1-7 2002 RC216
13. M.-E. Fortier, R. Joober, G.N. Luheshi, and P. Boska Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult offspring J. Psychiatr. Res. 38 2004 335 345
14. D.A. Gayle, R. Beloosesky, M. Desai, F. Amidi, S.E. Nunez, and M.G. Ross Maternal lipopolysaccharide induces cytokines in the amniotic fluid and corticotrophin releasing hormone in the fetal rat brain Am. J. Physiol., Regul. Integr. Comp. Physiol. 286 2004 R1024 R1029
15. H.A. Gelbard, K.A. Dzenko, D. DiLoreto, C. del Cerro, M. del Cerro, and L.G. Epstein Neurotoxic effects of tumor necrosis factor in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis Dev. Neurosci. 15 1993 417 422
16. J.H. Gilmore, and L.F. Jarskog Exposure to infection and brain development: cytokines in the pathogenesis of schizophrenia Schizophr. Res. 24 1997 365 367
17. J.H. Gilmore, L.F. Jarskog, and S. Vadlamudi Maternal infection regulated BDNF and NGF in fetal and neonatal brain and maternal fetal unit of the rat J. Neuroimmunol. 138 2003 49 55
18. J.H. Gilmore, L.F. Jarskog, S. Vadlamudi, and J.M. Lauder Prenatal infection and risk for schizophrenia: IL-1 β, IL-6, and TNFα inhibit cortical neuron dendrite development Neuropsychopharmacology 29 2004 1221 1229
19. J. Haddad, V. Vilge, J.G. Juif, M. Maitre, L. Donato, and J. Messer Beta-nerve growth factor levels in newborn cord sea Pediatr. Res. 35 1994 637 639
20. L.F. Jarskog, H. Xiao, M.B. Wilkie, J.M. Lauder, and J.H. Gilmore Cytokine regulation of fetal dopaminergic and serotonergic neuron survival in vitro Int. J. Dev. Neurosci. 15 1997 711 716
21. G.H. Jeohn, L.Y. Kong, B. Wilson, and J. Hong Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures J. Neuroimmunol. 85 1998 1 10
22. H. Kadhim, B. Tabarki, C. de Pez, and G. Sebrie Cytokine immunoreactivity in cortical and subcortical neurons in periventricular leukomalacia: are cytokines implicated in neuronal dysfunction in cerebral palsy? Acta Neuropathol. 105 2003 209 216
23. M. Kimura, L.A. Toth, H. Agonstini, A.B. Cady, J.A. Majde, and J.M. Krueger Comparison of acute phase responses induced in rabbits by lipopolysaccaride and double-stranded RNA Am. J. Physiol. 276 1994 R1597 R1605
24. D. MacGrogan, J.P. Saint-Andre, and E. Dicou Expression of nerve growth factor and nerve growth factor receptor genes in human tissues and in prostatic adenocarcinoma cell lines J. Neurochem. 59 1992 1381 1391
25. C.E. Marx, B.J. Vance, L.F. Jarskog, N.C. Chescheir, and J.H. Gilmore Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 levels in human amniotic fluid Am. J. Obstet. Gynecol. 181 1999 1125 1230
26. C.E. Marx, L.F. Jarskog, J.M. Lauder, J.A. Lieberman, and J.H. Gilmore Cytokine effects on cortical neuron MAP-2 immunoreactivity: implications for schizophrenia Biol. Psychiatry 50 2001 743 749
27. S. Nadeau, and S. Rivest Regulation of the gene encoding tumor necrosis factor alpha (TNF-α) in the rat brain and pituitary in response to different models of systemic immune challenge J. Neuropathol. Exp. Neurol. 58 1999 61 77
28. K.B. Nelson, J.K. Grether, L.A. Croen, J.M. Dambrosia, B.F. Dickens, L.L. Jelliffe, R.L. Hansen, and T.M. Phillips Neuropeptides and neurotrophins in the neonatal blood of children with autism or mental retardation Ann. Neurol. 49 2001 597 606
29. H. Neumann, R. Schweigreiter, T. Yamashita, K. Rosenkranz, H. Wekerle, and Y.-A. Barde Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism J. Neurosci. 22 2002 854 862
30. P. Rantakallio, and L. Von Wendt Risk factors for mental retardation Arch. Dis. Child. 60 1985 946 952
31. K. Roessler, G. Suchanek, H. Breitschope, K. Kitz, C. Matula, H. Lassmann, and W.T. Koos Detection of tumor necrosis factor protein and messenger RNA in human glial brain tumors: comparison of immunohistochemistry with in situ hybridization using molecular probes J. Neurosurg. 83 1995 291 297
32. L. Shi, S.H. Fatemi, R.W. Sidewell, and P.H. Patterson Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring J. Neurosci. 23 2003 297 302
33. N.P. Turrin, D. Gayle, S.E. Ilyin, M.C. Flynn, W. Langhans, G.J. Schwartz, and C.R. Plata-Salaman Pro-inflammatory and anti-inflammatory cytokine mRNA production in the periphery and brain following intraperitoneal administration of bacterial lipopolysaccharide Brain Res. Bull. 54 2001 443 453
34. S. Uchida, Y. Inanaga, M. Kobayashi, S. Hurukawa, M. Araie, and N. Sakuragawa Neurotrophic function of conditioned medium from human amniotic epithelial cells J. Neurosci. Res. 62 2000 585 590
35. A. Urakubo, L.F. Jarskog, J.A. Lieberman, and J.H. Gilmore Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain Schizophr. Res. 47 2001 27 36
36. J. Xu, G. Fan, S. Chen, Y. Wu, X.M. Xu, and C.Y. Hsu Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats Brain Res. Mol. Brain Res. 59 1998 135 142
37. L. Yang, K. Lindholm, Y. Konishi, and Y. Shen Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways J. Neurosci. 22 2002 3025 3032
38. L. Zuckerman, M. Rehavi, and I. Weiner Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia Neuropsychopharmacology 25 2003 1778 1789
39. L. Zuckerman, and I. Weiner Post-pubertal emergence of disrupted latent inhibition following prenatal immune activation Psychopharmacology 169 2003 308 313