Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia

Schizophrenia Research

Volumn 49, Issue 1-2, 2001, Pages 171-178

  Braff, David L ^a   Geyer, Mark A ^a   Light, Gregory A ^a   Sprock, Joyce ^a   Perry, William ^a   Cadenhead, Kristin S ^a   Swerdlow, Neal R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gating; Prepulse inhibition; Schizophrenia; Startle

Indexed keywords

ADULT; ANALYTIC METHOD; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; INFORMATION PROCESSING; MALE; METHODOLOGY; NEUROBIOLOGY; PREPULSE INHIBITION; PRIORITY JOURNAL; PURE TONE AUDIOMETRY; SCHIZOPHRENIA; STARTLE REFLEX; STIMULUS RESPONSE; WHITE NOISE;

ADULT; BRAIN; FEMALE; HUMANS; INHIBITION (PSYCHOLOGY); MALE; PERCEPTUAL DISORDERS; SCHIZOPHRENIA; STARTLE REACTION;

EID: 0035870801     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(00)00139-0     Document Type: Article

References (41)

1. Andreasen N.C. Scale for the Assessment of Negative Symptoms (SANS). 1984;University of Iowa, Iowa City, IA.
2. Andreasen N.C. Scale for the Assessment of Positive Symptoms (SAPS). 1984;University of Iowa, Iowa City, IA.
3. Bleuler E., Zinken J. Dementia Praecox; or, The Group of schizophrenias. 1952;International Universities Press, New York.
4. Blumenthal, T.D., 1999. Short lead interval startle modification. In: Dawson, M.E., Schell, A.M., Böhmelt, A.H. (Eds.) Startle Modification: Implications for Neuroscience Cognitive Science and Clinical Science. Cambridge University Press, New York, pp. 51-71.
5. Bolino F., Di Michele V., Di Cicco L., Manna V., Daneluzzo E., Casacchia M. Sensorimotor gating and habituation evoked by electro-cutaneous stimulation in schizophrenia. Biol. Psychiatry. 36:1994;670-679.
6. Braff D.L., Stone C., Callaway E., Geyer M.A., Glick I., Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology. 15:1978;339-343.
7. Braff, D.L., Saccuzzo, D.P., Geyer, M.A., 1991. Information processing dysfunction in schizophrenia: Studies of visual backward masking, sensorimotor gating, and habituation. In: Steinhauer, S.R., Gruzelier, J.H., Zubin, J. (Eds), Handbook of Schizophrenia, Volume 5. Neuropsychology, Psychophysiology and Information Processing. Elsevier Publishers, Amsterdam, pp. 303-334.
8. Braff D.L., Grillon C., Geyer M.A. Gating and habituation of the startle reflex in schizophrenic patients. Arch. Gen. Psychiatry. 49:1992;206-215.
9. Braff D.L. Information processing and attention dysfunctions in schizophrenia. Schizophr. Bull. 19:1993;233-259.
10. Braff D.L. Psychophysiological and information processing approaches to schizophrenia. Charney D.S., Nestler E., Bunney B.S. Neurobiological Foundation of Mental Illness. 1999;258-271 Oxford University Press, New York.
11. Braff D.L., Swerdlow N.R., Geyer M.A. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients. Am. J. Psychiatry. 156:1999;596-602.
12. Cadenhead K.S., Geyer M.A., Braff D.L. Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am. J. Psychiatry. 150:1993;1862-1867.
13. Cadenhead K.S., Swerdlow N.R., Shafer K.M., Diaz M., Braff D.L. Modulation of the startle response and startle laterality in relatives of schizophrenia patients and Schizotypal Personality Disordered subjects: evidence of inhibitory deficits. Am. J. Psychiatry. 157:2000;1660-1668.
14. Castellanos F.X., Fine E.J., Kaysen D., Marsh W.L., Rapoport J.L., Hallett M. Sensorimotor gating in boys with Tourette's syndrome and ADHD: preliminary results. Biol. Psychiatry. 39:1996;33-41.
15. Dawson M.E., Hazlett E.A., Filion D.L., Nuechterlein K.H., Schell A.M. Attention and schizophrenia: impaired modulation of the startle reflex. J. Abnorm. Psychol. 102:1993;633-641.
16. First M.B., Spitzer R.L., Gibbon M., Williams J.B. Structured Clinical Interview for DSM-IV Axis I Disorders - Patient Edition (SCID-I/P, Version 2.0). 1995;Biometrics Research Department, New York State Psychiatric Institute, New York.
17. First M.B., Spitzer R.L., Gibbon M., Williams J.B. Structured Clinical Interview for DSM-IV Axis I Disorders - Non-Patient Edition (SCID-I/NP, Version 2.0). 1996;Biometrics Research Department, New York State Psychiatric Institute, New York.
18. First M.B., Spitzer R.L., Gibbon M., Williams J.B., Benjamin L. Structured Clinical Interview for DSM-IV Axis II Personality Disorders - (SCID-II, Version 2.0). 1996;Biometrics Research Department, New York State Psychiatric Institute, New York.
19. Freedman R., Coon H., Myles-Worsley M., Orr-Urtreger A., Olincy A., Davis A., Polymeropoulos M., Holik J., Hopkins J., Hoff M., Rosenthal J., Waldo M.C., Reimherr F., Wender P., Yaw J., Young D.A., Breese C.R., Adams C., Patterson D., Adler L.E., Kruglyak L., Leonard S., Byerley W. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc. Natl. Acad. Sci. USA. 94:1997;587-592.
20. Graham F.K. Presidential Address, 1974. The more or less startling effects of weak prestimulation. Psychophysiology. 12:1975;238-248.
21. Grillon C., Ameli R., Charney D.S., Krystal J., Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biol. Psychiatry. 32:1992;939-943.
22. Hoffman H.S., Searle J.L. Acoustic and temporal factors in the evocation of startle. J. Acoust. Soc. Am. 43:1968;269-282.
23. Ison J.R., McAdam D.W., Hammond G.R. Latency and amplitude changes in the acoustic startle reflex of the rat produced by variation in auditory prestimulation. Physiol. Behav. 10:1973;1035-1039.
24. Karper L.P., Freeman G.K., Grillon C., Morgan C.A. 3rd, Charney D.S., Krystal J.H. Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. J. Neuropsychiatry Clin. Neurosci. 8:1996;60-66.
25. Kessler K.A., Waletzky J.P. Clinical use of the antipsychotics. Am. J. Psychiatry. 138:1981;202-209.
26. Kumari V., Soni W., Sharma T. Normalization of information processing deficits in schizophrenia with clozapine. Am. J. Psychiatry. 156:1999;1046-1051.
27. McDowd J.M., Filion D.L., Harris M.J., Braff D.L. Sensory gating and inhibitory function in late-life schizophrenia. Schizophr. Bull. 19:1993;733-746.
28. McGhie A., Chapman J. Disorders of attention and perception in early schizophrenia. Br. J. Med. Psychol. 34:1961;103-116.
29. Parwani, A., Duncan, E.J., Bartlett, E., Madonick, S.H., Efferen, T.R., Rajan, R., Sanfilipo, M., Chappell, P.B., Chakravorty, S., Gonzenbach, S., Ko, G.N., Rotrosen, J.P., 2000. Impaired prepulse inhibition of acoustic startle in schizophrenia. Biol. Psychiatry 47, 662-669.
30. Perry W., Braff D.L. Information-processing deficits and thought disorder in schizophrenia. Am. J. Psychiatry. 151:1994;363-367.
31. Perry W., Geyer M.A., Braff D.L. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients. Arch. Gen. Psychiatry. 56:1999;277-281.
32. Simons R.F., Giardina B.D. Reflex modification in psychosis-prone young adults. Psychophysiology. 29:1992;8-16.
33. Swerdlow N.R., Caine S.B., Braff D.L., Geyer M.A. The neural substrates of sensorimotor gating of the startle reflex: A review of recent findings and their implications. J. Psychopharmacol. 6:1992;176-190.
34. Swerdlow N.R., Benbow C.H., Zisook S., Geyer M.A., Braff D.L. A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder. Biol. Psychiatry. 33:1993;298-301.
35. Swerdlow N.R., Braff D.L., Taaid N., Geyer M.A. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch. Gen. Psychiatry. 51:1994;139-154.
36. Swerdlow N.R., Filion D., Geyer M.A., Braff D.L. 'Normal' personality correlates of sensorimotor, cognitive, and visuospatial gating. Biol. Psychiatry. 37:1995;286-299.
37. Swerdlow N.R., Paulsen J., Braff D.L., Butters N., Geyer M.A., Swenson M.R. Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J. Neurol. Neurosurg. Psychiatry. 58:1995;192-200.
38. Swerdlow N.R., Geyer M.A. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr. Bull. 24:1998;285-301.
39. Swerdlow, N.R., Geyer, M.A., Blumenthal, T.D., Hartman, P.L., 1999. Effects of discrete acoustic prestimuli on perceived intensity and behavioral responses to startling acoustic and tactile stimuli. Psychobiology 27, 547-556.
40. Weike A.I., Bauer U., Hamm A.O. Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients. Biol. Psychiatry. 47:2000;61-70.
41. Wynn J.K., Dawson M.E., Schell A.M. Discrete and continuous prepulses have differential effects on startle prepulse inhibition and skin conductance orienting. Psychophysiology. 37:2000;224-230.