Effects of subcutaneous LPS injection on gestational length and intrauterine and neonatal mortality in mice

NeuroImmunoModulation

Volumn 22, Issue 4, 2015, Pages 274-278

  Pujol Lopez, Yara ^a   Steinbusch, Harry W M ^a   Rutten, Bart ^a   Kenis, Gunter ^a   Van Den Hove, Daniel L ^a,b   Myint, Aye M ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Infection; Mortality; Mouse; Pregnancy

Indexed keywords

LIPOPOLYSACCHARIDE;

ADULT; AFFECTIVE PSYCHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GESTATION PERIOD; INTRAUTERINE INFECTION; LITTER SIZE; MOUSE; NEWBORN MORTALITY; NONHUMAN; PERINATAL MORTALITY; PRENATAL MORTALITY; PRIORITY JOURNAL; PROGENY; RANDOMIZATION; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; FETUS DEATH; INFLAMMATION; NEWBORN; PREGNANCY; PREGNANCY COMPLICATION;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; FEMALE; FETAL DEATH; INFLAMMATION; LIPOPOLYSACCHARIDES; LITTER SIZE; MICE; MICE, INBRED C57BL; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY COMPLICATIONS, INFECTIOUS; RANDOM ALLOCATION;

EID: 84928424254     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000368554     Document Type: Article

References (27)

1. Patterson PH: Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness. Curr Opin Neurobiol 2002; 12: 115-118.
2. Meyer U, Yee BK, Feldon J: The neurodevelopmental impact of prenatal infections at different times of pregnancy: the earlier the worse? Neuroscientist 2007; 13: 241-256.
3. Brown AS: Prenatal infection as a risk factor for schizophrenia. Schizophr Bull 2006; 32: 200-202.
4. Parboosing R, et al: Gestational influenza and bipolar disorder in adult offspring. JAMA Psychiatry 2013; 70:677-685.
5. Atladottir HO, et al: Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J Autism Dev Disord 2010; 40: 1423-1430.
6. Boksa P: Effects of prenatal infection on brain development and behavior: a review of findings from animal models. Brain Behav Immun 2010; 24: 881-897.
7. Licinio J: Central nervous system cytokines and their relevance for neurotoxicity and apoptosis. J Neural Transm Suppl 1997; 49: 169-175.
8. Grinevich V, et al: Effect of repeated lipopolysaccharide administration on tissue cytokine expression and hypothalamic-pituitary-adrenal axis activity in rats. J Neuroendocrinol 2001; 13: 711-723.
9. Lante F, et al: Late N-acetylcysteine treatment prevents the deficits induced in the offspring of dams exposed to an immune stress during gestation. Hippocampus 2008; 18: 602-609.
10. Hao LY, et al: Prenatal exposure to lipopolysaccharide results in cognitive deficits in ageincreasing offspring rats. Neuroscience 2010; 166: 763-770.
11. Golan HM, et al: Specific neurodevelopmental damage in mice offspring following maternal inflammation during pregnancy. Neuropharmacology 2005; 48: 903-917.
12. Renaud SJ, et al: Spontaneous pregnancy loss mediated by abnormal maternal inflammation in rats is linked to deficient uteroplacental perfusion. J Immunol 2011; 186: 1799-1808.
13. Chlodzinska N, et al: Lipopolysaccharide injected to pregnant mice affects behavior of their offspring in adulthood. Acta Neurobiol Exp (Wars) 2011; 71: 519-527.
14. Xu DX, et al: Tumor necrosis factor alpha partially contributes to lipopolysaccharide-induced intra-uterine fetal growth restriction and skeletal development retardation in mice. Toxicol Lett 2006; 163: 20-29.
15. Buhimschi IA, Buhimschi CS, Weiner CP: Protective effect of N-acetylcysteine against fetal death and preterm labor induced by maternal inflammation. Am J Obstet Gynecol 2003; 188: 203-208.
16. Salminen A, et al: Maternal endotoxin-induced preterm birth in mice: fetal responses in Toll-like receptors, collectins, and cytokines. Pediatr Res 2008; 63: 280-286.
17. Gaines Das R, North D: Implications of experimental technique for analysis and interpretation of data from animal experiments: outliers and increased variability resulting from failure of intraperitoneal injection procedures. Lab Anim 2007; 41: 312-320.
18. Mijovic JE, et al: Tyrphostins inhibit lipopolysaccharide induced preterm labor in mice. J Perinat Med 2002; 30: 297-300.
19. Nakamura A, et al: Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice. J Exp Med 2003; 197: 669-674.
20. Wang X, et al: Effects of intrauterine inflammation on the developing mouse brain. Brain Res 2007; 1144: 180-185.
21. Kohmura Y, et al: Lipopolysaccharide (LPS)-induced intra-uterine fetal death (IUFD) in mice is principally due to maternal cause but not fetal sensitivity to LPS. Microbiol Immunol 2000; 44: 897-904.
22. Steward JP, et al: Errors in the technique of intraperitoneal injection of mice. Appl Microbiol 1968; 16: 1418.
23. Miner NA, Koehler J, Greenaway L: Intraperitoneal injection of mice. Appl Microbiol 1969; 17: 250-251.
24. Cho YJ, et al: Kinetics of proinflammatory cytokines after intraperitoneal injection of tribromoethanol and a tribromoethanol/xylazine combination in ICR mice. Lab Anim Res 2011; 27: 197-203.
25. Carey LC, et al: Zinc treatment prevents lipopolysaccharide-induced teratogenicity in mice. Birth Defects Res A Clin Mol Teratol 2003; 67: 240-245.
26. Chua JS, Rofe AM, Coyle P: Dietary zinc supplementation ameliorates LPS-induced teratogenicity in mice. Pediatr Res 2006; 59: 355-358.
27. Chua JS, et al: Prenatal exposure to lipopolysaccharide results in neurodevelopmental damage that is ameliorated by zinc in mice. Brain Behav Immun 2012; 26: 326-336.