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Volumn 23, Issue 5, 2018, Pages 455-466

Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease

Author keywords

active disease; biomarkers; cure; incipient tuberculosis; latent infection

Indexed keywords

BACTERIAL DNA; BIOLOGICAL MARKER; FIBRINOGEN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 23; KI 67 ANTIGEN; SCLEROPROTEIN; SCLEROPROTEIN 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VOLATILE ORGANIC COMPOUND; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; BCG VACCINE; PROTEOME; TRANSCRIPTOME;

EID: 85042064378     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.13272     Document Type: Review
Times cited : (126)

References (120)
  • 1
    • 85045558487 scopus 로고    scopus 로고
    • Tuberculosis fact sheet,, Available from
    • WHO. Tuberculosis fact sheet, 2017. Available from URL: http://www.who.int/mediacentre/factsheets/fs104/en/
    • (2017)
  • 2
    • 84994259668 scopus 로고    scopus 로고
    • The global burden of latent tuberculosis infection: a re-estimation using mathematical modelling
    • Houben RM, Dodd PJ. The global burden of latent tuberculosis infection: a re-estimation using mathematical modelling. PLoS Med. 2016; 13: e1002152.
    • (2016) PLoS Med. , vol.13
    • Houben, R.M.1    Dodd, P.J.2
  • 3
    • 77951873829 scopus 로고    scopus 로고
    • HIV infection-associated tuberculosis: the epidemiology and the response
    • Getahun H, Gunneberg C, Granich R, Nunn P. HIV infection-associated tuberculosis: the epidemiology and the response. Clin. Infect. Dis. 2010; 50(Suppl. 3): S201–7.
    • (2010) Clin. Infect. Dis. , vol.50 , pp. S201-S207
    • Getahun, H.1    Gunneberg, C.2    Granich, R.3    Nunn, P.4
  • 4
    • 84899820143 scopus 로고    scopus 로고
    • Biologics and tuberculosis risk: the rise and fall of an old disease and its new resurgence
    • Cantini F, Goletti D. Biologics and tuberculosis risk: the rise and fall of an old disease and its new resurgence. J. Rheumatol. Suppl. 2014; 91: 1–3.
    • (2014) J. Rheumatol. Suppl. , vol.91 , pp. 1-3
    • Cantini, F.1    Goletti, D.2
  • 6
    • 84938532232 scopus 로고    scopus 로고
    • Risk assessment of tuberculosis in contacts by IFN-gamma release assays. A Tuberculosis Network European Trials Group Study., Am. J. Respir. Crit. Care Med., 2015; 191 1176–84
    • Zellweger JP, Sotgiu G, Block M, Dore S, Altet N, Blunschi R, Bogyi M, Bothamley G, Bothe C, Codecasa L et al.; TBNET. Risk assessment of tuberculosis in contacts by IFN-gamma release assays. A Tuberculosis Network European Trials Group Study. Am. J. Respir. Crit. Care Med. 2015; 191: 1176–84.
    • Zellweger, J.P.1    Sotgiu, G.2    Block, M.3    Dore, S.4    Altet, N.5    Blunschi, R.6    Bogyi, M.7    Bothamley, G.8    Bothe, C.9    Codecasa, L.10
  • 8
    • 56249149272 scopus 로고    scopus 로고
    • The diagnosis and misdiagnosis of tuberculosis
    • Davies PD, Pai M. The diagnosis and misdiagnosis of tuberculosis. Int. J. Tuberc. Lung Dis. 2008; 12: 1226–34.
    • (2008) Int. J. Tuberc. Lung Dis. , vol.12 , pp. 1226-1234
    • Davies, P.D.1    Pai, M.2
  • 11
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 2001; 69: 89–95.
    • (2001) Clin. Pharmacol. Ther. , vol.69 , pp. 89-95
  • 12
    • 82755187564 scopus 로고    scopus 로고
    • Extracellular microRNA: a new source of biomarkers
    • Etheridge A, Lee I, Hood L, Galas D, Wang K. Extracellular microRNA: a new source of biomarkers. Mutat. Res. 2011; 717: 85–90.
    • (2011) Mutat. Res. , vol.717 , pp. 85-90
    • Etheridge, A.1    Lee, I.2    Hood, L.3    Galas, D.4    Wang, K.5
  • 13
    • 84901514004 scopus 로고    scopus 로고
    • Prognostic and predictive biomarkers: tools in personalized oncology
    • Nalejska E, Maczynska E, Lewandowska MA. Prognostic and predictive biomarkers: tools in personalized oncology. Mol. Diagn. Ther. 2014; 18: 273–84.
    • (2014) Mol. Diagn. Ther. , vol.18 , pp. 273-284
    • Nalejska, E.1    Maczynska, E.2    Lewandowska, M.A.3
  • 15
    • 84947795659 scopus 로고    scopus 로고
    • Biomarker: predictive or prognostic?
    • Ballman KV. Biomarker: predictive or prognostic? J. Clin. Oncol. 2015; 33: 3968–71.
    • (2015) J. Clin. Oncol. , vol.33 , pp. 3968-3971
    • Ballman, K.V.1
  • 18
    • 84962558465 scopus 로고    scopus 로고
    • Molecular diagnosis of urinary tract infections by semi-quantitative detection of uropathogens in a routine clinical hospital setting
    • van der Zee A, Roorda L, Bosman G, Ossewaarde JM. Molecular diagnosis of urinary tract infections by semi-quantitative detection of uropathogens in a routine clinical hospital setting. PLoS One 2016; 11: e0150755.
    • (2016) PLoS One , vol.11
    • van der Zee, A.1    Roorda, L.2    Bosman, G.3    Ossewaarde, J.M.4
  • 20
    • 67650680030 scopus 로고    scopus 로고
    • Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods
    • Green C, Huggett JF, Talbot E, Mwaba P, Reither K, Zumla AI. Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods. Lancet Infect. Dis. 2009; 9: 505–11.
    • (2009) Lancet Infect. Dis. , vol.9 , pp. 505-511
    • Green, C.1    Huggett, J.F.2    Talbot, E.3    Mwaba, P.4    Reither, K.5    Zumla, A.I.6
  • 23
    • 85029173801 scopus 로고    scopus 로고
    • Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays
    • Kerkhoff AD, Barr DA, Schutz C, Burton R, Nicol MP, Lawn SD, Meintjes G. Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays. Sci. Rep. 2017; 7: 10931.
    • (2017) Sci. Rep. , vol.7 , pp. 10931
    • Kerkhoff, A.D.1    Barr, D.A.2    Schutz, C.3    Burton, R.4    Nicol, M.P.5    Lawn, S.D.6    Meintjes, G.7
  • 24
    • 85015711449 scopus 로고    scopus 로고
    • Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort
    • Lawn SD, Kerkhoff AD, Burton R, Schutz C, Boulle A, Vogt M, Gupta-Wright A, Nicol MP, Meintjes G. Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort. BMC Med. 2017; 15: 67.
    • (2017) BMC Med. , vol.15 , pp. 67
    • Lawn, S.D.1    Kerkhoff, A.D.2    Burton, R.3    Schutz, C.4    Boulle, A.5    Vogt, M.6    Gupta-Wright, A.7    Nicol, M.P.8    Meintjes, G.9
  • 25
    • 80053449236 scopus 로고    scopus 로고
    • Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis
    • Minion J, Leung E, Talbot E, Dheda K, Pai M, Menzies D. Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis. Eur. Respir. J. 2011; 38: 1398–405.
    • (2011) Eur. Respir. J. , vol.38 , pp. 1398-1405
    • Minion, J.1    Leung, E.2    Talbot, E.3    Dheda, K.4    Pai, M.5    Menzies, D.6
  • 27
    • 0032957234 scopus 로고    scopus 로고
    • Pathophysiology of antigen 85 in patients with active tuberculosis: antigen 85 circulates as complexes with fibronectin and immunoglobulin G
    • Bentley-Hibbert SI, Quan X, Newman T, Huygen K, Godfrey HP. Pathophysiology of antigen 85 in patients with active tuberculosis: antigen 85 circulates as complexes with fibronectin and immunoglobulin G. Infect. Immun. 1999; 67: 581–8.
    • (1999) Infect. Immun. , vol.67 , pp. 581-588
    • Bentley-Hibbert, S.I.1    Quan, X.2    Newman, T.3    Huygen, K.4    Godfrey, H.P.5
  • 34
    • 84865792720 scopus 로고    scopus 로고
    • New pathways of protective and pathological host defense to mycobacteria
    • Ottenhoff TH. New pathways of protective and pathological host defense to mycobacteria. Trends Microbiol. 2012; 20: 419–28.
    • (2012) Trends Microbiol. , vol.20 , pp. 419-428
    • Ottenhoff, T.H.1
  • 35
    • 84867198092 scopus 로고    scopus 로고
    • The knowns and unknowns of the immunopathogenesis of tuberculosis
    • Ottenhoff TH. The knowns and unknowns of the immunopathogenesis of tuberculosis. Int. J. Tuberc. Lung Dis. 2012; 16: 1424–32.
    • (2012) Int. J. Tuberc. Lung Dis. , vol.16 , pp. 1424-1432
    • Ottenhoff, T.H.1
  • 37
    • 84959505947 scopus 로고    scopus 로고
    • Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
    • Sweeney TE, Braviak L, Tato CM, Khatri P. Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis. Lancet Respir. Med. 2016; 4: 213–24.
    • (2016) Lancet Respir. Med. , vol.4 , pp. 213-224
    • Sweeney, T.E.1    Braviak, L.2    Tato, C.M.3    Khatri, P.4
  • 44
    • 84877732147 scopus 로고    scopus 로고
    • Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting
    • Chegou NN, Detjen AK, Thiart L, Walters E, Mandalakas AM, Hesseling AC, Walzl G. Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting. PLoS One 2013; 8: e64226.
    • (2013) PLoS One , vol.8
    • Chegou, N.N.1    Detjen, A.K.2    Thiart, L.3    Walters, E.4    Mandalakas, A.M.5    Hesseling, A.C.6    Walzl, G.7
  • 45
    • 20144387962 scopus 로고    scopus 로고
    • IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection
    • Azzurri A, Sow OY, Amedei A, Bah B, Diallo S, Peri G, Benagiano M, D'Elios MM, Mantovani A, Del Prete G. IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection. Microbes Infect. 2005; 7: 1–8.
    • (2005) Microbes Infect. , vol.7 , pp. 1-8
    • Azzurri, A.1    Sow, O.Y.2    Amedei, A.3    Bah, B.4    Diallo, S.5    Peri, G.6    Benagiano, M.7    D'Elios, M.M.8    Mantovani, A.9    Del Prete, G.10
  • 48
    • 57549110589 scopus 로고    scopus 로고
    • Is IP-10 a better biomarker for active and latent tuberculosis in children than IFNgamma?
    • Whittaker E, Gordon A, Kampmann B. Is IP-10 a better biomarker for active and latent tuberculosis in children than IFNgamma? PLoS One 2008; 3: e3901.
    • (2008) PLoS One , vol.3
    • Whittaker, E.1    Gordon, A.2    Kampmann, B.3
  • 54
    • 84982283783 scopus 로고    scopus 로고
    • Diagnostic potential of novel salivary host biomarkers as candidates for the immunological diagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
    • Jacobs R, Maasdorp E, Malherbe S, Loxton AG, Stanley K, van der Spuy G, Walzl G, Chegou NN. Diagnostic potential of novel salivary host biomarkers as candidates for the immunological diagnosis of tuberculosis disease and monitoring of tuberculosis treatment response. PLoS One 2016; 11: e0160546.
    • (2016) PLoS One , vol.11
    • Jacobs, R.1    Maasdorp, E.2    Malherbe, S.3    Loxton, A.G.4    Stanley, K.5    van der Spuy, G.6    Walzl, G.7    Chegou, N.N.8
  • 62
    • 33749027771 scopus 로고    scopus 로고
    • Region of difference 1 antigen-specific CD4+ memory T cells correlate with a favorable outcome of tuberculosis
    • Goletti D, Butera O, Bizzoni F, Casetti R, Girardi E, Poccia F. Region of difference 1 antigen-specific CD4+ memory T cells correlate with a favorable outcome of tuberculosis. J. Infect. Dis. 2006; 194: 984–92.
    • (2006) J. Infect. Dis. , vol.194 , pp. 984-992
    • Goletti, D.1    Butera, O.2    Bizzoni, F.3    Casetti, R.4    Girardi, E.5    Poccia, F.6
  • 64
    • 84908142553 scopus 로고    scopus 로고
    • Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study
    • Portevin D, Moukambi F, Clowes P, Bauer A, Chachage M, Ntinginya NE, Mfinanga E, Said K, Haraka F, Rachow A et al. Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study. Lancet Infect. Dis. 2014; 14: 931–8.
    • (2014) Lancet Infect. Dis. , vol.14 , pp. 931-938
    • Portevin, D.1    Moukambi, F.2    Clowes, P.3    Bauer, A.4    Chachage, M.5    Ntinginya, N.E.6    Mfinanga, E.7    Said, K.8    Haraka, F.9    Rachow, A.10
  • 69
    • 84958859385 scopus 로고    scopus 로고
    • Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes
    • Naranbhai V, Fletcher HA, Tanner R, O'Shea MK, McShane H, Fairfax BP, Knight JC, Hill AV. Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes. EBioMedicine 2015; 2: 1619–26.
    • (2015) EBioMedicine , vol.2 , pp. 1619-1626
    • Naranbhai, V.1    Fletcher, H.A.2    Tanner, R.3    O'Shea, M.K.4    McShane, H.5    Fairfax, B.P.6    Knight, J.C.7    Hill, A.V.8
  • 70
    • 84893337314 scopus 로고    scopus 로고
    • Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy
    • Naranbhai V, Hill AV, Abdool Karim SS, Naidoo K, Abdool Karim Q, Warimwe GM, McShane H, Fletcher H. Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy. J. Infect. Dis. 2014; 209: 500–9.
    • (2014) J. Infect. Dis. , vol.209 , pp. 500-509
    • Naranbhai, V.1    Hill, A.V.2    Abdool Karim, S.S.3    Naidoo, K.4    Abdool Karim, Q.5    Warimwe, G.M.6    McShane, H.7    Fletcher, H.8
  • 74
    • 80052339714 scopus 로고    scopus 로고
    • Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis
    • Steingart KR, Flores LL, Dendukuri N, Schiller I, Laal S, Ramsay A, Hopewell PC, Pai M. Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis. PLoS Med. 2011; 8: e1001062.
    • (2011) PLoS Med. , vol.8
    • Steingart, K.R.1    Flores, L.L.2    Dendukuri, N.3    Schiller, I.4    Laal, S.5    Ramsay, A.6    Hopewell, P.C.7    Pai, M.8
  • 80
  • 83
    • 84959506470 scopus 로고    scopus 로고
    • Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis
    • Dorhoi A, Kaufmann SH. Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis. Semin. Immunopathol. 2016; 38: 153–66.
    • (2016) Semin. Immunopathol. , vol.38 , pp. 153-166
    • Dorhoi, A.1    Kaufmann, S.H.2
  • 84
    • 84899797129 scopus 로고    scopus 로고
    • The spectrum of tuberculosis infection: new perspectives in the era of biologics
    • Delogu G, Goletti D. The spectrum of tuberculosis infection: new perspectives in the era of biologics. J. Rheumatol. Suppl. 2014; 91: 11–6.
    • (2014) J. Rheumatol. Suppl. , vol.91 , pp. 11-16
    • Delogu, G.1    Goletti, D.2
  • 87
    • 84943370830 scopus 로고    scopus 로고
    • Early biomarkers and regulatory innovation in multidrug-resistant tuberculosis
    • Wallis RS, Peppard T. Early biomarkers and regulatory innovation in multidrug-resistant tuberculosis. Clin. Infect. Dis. 2015; 61(Suppl. 3): S160–3.
    • (2015) Clin. Infect. Dis. , vol.61 , pp. S160-S163
    • Wallis, R.S.1    Peppard, T.2
  • 89
    • 84909644357 scopus 로고    scopus 로고
    • Host RNA signatures for diagnostics: an example from paediatric tuberculosis in Africa
    • Kaforou M, Wright VJ, Levin M. Host RNA signatures for diagnostics: an example from paediatric tuberculosis in Africa. J. Infect. 2014; 69(Suppl. 1): S28–31.
    • (2014) J. Infect. , vol.69 , pp. S28-31
    • Kaforou, M.1    Wright, V.J.2    Levin, M.3
  • 91
    • 84875382846 scopus 로고    scopus 로고
    • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG a randomised, placebo-controlled phase 2b trial
    • Tameris MD, Hatherill M, Landry BS, Scriba TJ, Snowden MA, Lockhart S, Shea JE, McClain JB, Hussey GD, Hanekom WA et al.; MVA85A 020 Trial Study Team Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial. Lancet 2013; 381: 1021–8.
    • (2013) Lancet , vol.381 , pp. 1021-1028
    • Tameris, M.D.1    Hatherill, M.2    Landry, B.S.3    Scriba, T.J.4    Snowden, M.A.5    Lockhart, S.6    Shea, J.E.7    McClain, J.B.8    Hussey, G.D.9    Hanekom, W.A.10
  • 94
    • 23244451582 scopus 로고    scopus 로고
    • Biomarkers and surrogate markers: an FDA perspective
    • Katz R. Biomarkers and surrogate markers: an FDA perspective. NeuroRx 2004; 1: 189–95.
    • (2004) NeuroRx , vol.1 , pp. 189-195
    • Katz, R.1
  • 95
    • 0038628994 scopus 로고    scopus 로고
    • Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days
    • Jindani A, Dore CJ, Mitchison DA. Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days. Am. J. Respir. Crit. Care Med. 2003; 167: 1348–54.
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 1348-1354
    • Jindani, A.1    Dore, C.J.2    Mitchison, D.A.3
  • 96
    • 0027446941 scopus 로고
    • Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months
    • Mitchison DA. Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months. Am. Rev. Respir. Dis. 1993; 147: 1062–3.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 1062-1063
    • Mitchison, D.A.1
  • 102
    • 84881369293 scopus 로고    scopus 로고
    • Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment
    • Friedrich SO, Rachow A, Saathoff E, Singh K, Mangu CD, Dawson R, Phillips PP, Venter A, Bateson A, Boehme CC et al.; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics (PanACEA). Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment. Lancet Respir. Med. 2013; 1: 462–70.
    • (2013) Lancet Respir. Med , vol.1 , pp. 462-470
    • Friedrich, S.O.1    Rachow, A.2    Saathoff, E.3    Singh, K.4    Mangu, C.D.5    Dawson, R.6    Phillips, P.P.7    Venter, A.8    Bateson, A.9    Boehme, C.C.10
  • 104
    • 0038290334 scopus 로고    scopus 로고
    • The hunt for the elusive surrogate marker of sterilizing activity in tuberculosis treatment
    • Burman WJ. The hunt for the elusive surrogate marker of sterilizing activity in tuberculosis treatment. Am. J. Respir. Crit. Care Med. 2003; 167: 1299–301.
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 1299-1301
    • Burman, W.J.1
  • 109
    • 11844258823 scopus 로고    scopus 로고
    • Post-treatment changes of six cytokines in active pulmonary tuberculosis: differences between patients with stable or increased fibrosis
    • Ameglio F, Casarini M, Capoluongo E, Mattia P, Puglisi G, Giosue S. Post-treatment changes of six cytokines in active pulmonary tuberculosis: differences between patients with stable or increased fibrosis. Int. J. Tuberc. Lung Dis. 2005; 9: 98–104.
    • (2005) Int. J. Tuberc. Lung Dis. , vol.9 , pp. 98-104
    • Ameglio, F.1    Casarini, M.2    Capoluongo, E.3    Mattia, P.4    Puglisi, G.5    Giosue, S.6
  • 110
    • 75749090040 scopus 로고    scopus 로고
    • Association of reduced tumor necrosis factor alpha, gamma interferon, and interleukin-1beta (IL-1beta) but increased IL-10 expression with improved chest radiography in patients with pulmonary tuberculosis
    • Su WL, Perng WC, Huang CH, Yang CY, Wu CP, Chen JH. Association of reduced tumor necrosis factor alpha, gamma interferon, and interleukin-1beta (IL-1beta) but increased IL-10 expression with improved chest radiography in patients with pulmonary tuberculosis. Clin. Vaccine Immunol. 2010; 17: 223–31.
    • (2010) Clin. Vaccine Immunol. , vol.17 , pp. 223-231
    • Su, W.L.1    Perng, W.C.2    Huang, C.H.3    Yang, C.Y.4    Wu, C.P.5    Chen, J.H.6
  • 116
    • 84986207662 scopus 로고    scopus 로고
    • Preliminary data on precision of QuantiFERON-TB Plus performance
    • Cirillo DM, Barcellini L, Goletti D. Preliminary data on precision of QuantiFERON-TB Plus performance. Eur. Respir. J. 2016; 48: 955–6.
    • (2016) Eur. Respir. J. , vol.48 , pp. 955-956
    • Cirillo, D.M.1    Barcellini, L.2    Goletti, D.3
  • 117
    • 85021661733 scopus 로고    scopus 로고
    • QuantiFERON-TB(R) Gold Plus as a potential tuberculosis treatment monitoring tool
    • Kamada A, Amishima M. QuantiFERON-TB(R) Gold Plus as a potential tuberculosis treatment monitoring tool. Eur. Respir. J. 2017; 49.
    • (2017) Eur. Respir. J. , vol.49
    • Kamada, A.1    Amishima, M.2


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