Combined use of mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis

Clinical Infectious Diseases

Volumn 60, Issue 3, 2015, Pages 432-437

  Rozot, Virginie ^a,b   Patrizia, Amelio ^a   Vigano, Selena ^a   Mazza Stalder, Jesica ^a   Idrizi, Elita ^a   Day, Cheryl L ^b   Perreau, Matthieu ^a   Lazor Blanchet, Catherine ^a   Ohmiti, Khalid ^a   Goletti, Delia ^c   Bart, Pierre Alexandre ^a   Hanekom, Willem ^b   Scriba, Thomas J ^b   Nicod, Laurent ^a   Pantaleo, Giuseppe ^a,d   Harari, Alexandre ^a,d  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^d Swiss Vaccine Research Institute   (Switzerland)

Author keywords

active tuberculosis disease; CD8 T cells; diagnosis; functional profile; latent Mtb infection

Indexed keywords

CD3 ANTIBODY; CD4 ANTIBODY; CD8 ANTIBODY; CULTURE FILTRATE PROTEIN 10; CYTOKINE ANTIBODY; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON ANTIBODY; INTERLEUKIN 2 ANTIBODY; PROTEIN ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN;

ARTICLE; BACTERIUM CULTURE; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE COURSE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LATENT TUBERCULOSIS; MAJOR CLINICAL STUDY; MYCOBACTERIUM TUBERCULOSIS; PREDICTIVE VALUE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; TUBERCULOSIS; ADOLESCENT; ADULT; AGED; CHILD; FEMALE; IMMUNOLOGY; MALE; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; YOUNG ADULT;

EID: 84922443675     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu795     Document Type: Article

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