메뉴 건너뛰기




Volumn 34, Issue 2, 2014, Pages 245-255

Longitudinal immune responses and gene expression profiles in type 1 leprosy reactions

Author keywords

Biomarker; early diagnosis; gene profiles; leprosy reactions; T1R

Indexed keywords

CD68 ANTIGEN; CLOBETASOL PROPIONATE; CLOFAZIMINE; CXCL9 CHEMOKINE; DAPSONE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; METHOTREXATE; MINOCYCLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; OFLOXACIN; PREDNISOLONE; RIFAMPICIN; RNA; STEROID; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84898843454     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-013-9979-x     Document Type: Article
Times cited : (55)

References (39)
  • 1
    • 84863665454 scopus 로고    scopus 로고
    • Leprosy update, 2011
    • Sep 2
    • Leprosy update, 2011. Wkly Epidemiol Rec. 2011 Sep 2;86(36):389-99.
    • (2011) Wkly Epidemiol Rec. , vol.86 , Issue.36 , pp. 389-399
  • 2
    • 0013931934 scopus 로고
    • Classification of leprosy according to immunity. A five-group system
    • 1:STN:280:DyaF2s%2FhtVWluw%3D%3D 5950347
    • Ridley DS, Jopling WH. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis. 1966;34(3):255-73.
    • (1966) Int J Lepr Other Mycobact Dis , vol.34 , Issue.3 , pp. 255-273
    • Ridley, D.S.1    Jopling, W.H.2
  • 3
    • 84874077521 scopus 로고    scopus 로고
    • Borderline lepromatous leprosy in an Italian man
    • 3583305 23390219 10.4269/ajtmh.12-0214
    • Massone C, Clapasson A, Nunzi E. Borderline lepromatous leprosy in an Italian man. Am J Trop Med Hyg. 2013;88(2):211.
    • (2013) Am J Trop Med Hyg , vol.88 , Issue.2 , pp. 211
    • Massone, C.1    Clapasson, A.2    Nunzi, E.3
  • 4
    • 1842686127 scopus 로고    scopus 로고
    • Leprosy
    • 15081655 10.1016/S0140-6736(04)15952-7
    • Britton WJ, Lockwood DN. Leprosy. Lancet. 2004;363(9416):1209-19.
    • (2004) Lancet , vol.363 , Issue.9416 , pp. 1209-1219
    • Britton, W.J.1    Lockwood, D.N.2
  • 5
    • 84855263752 scopus 로고    scopus 로고
    • Cytokine and protein markers of leprosy reactions in skin and nerves: Baseline results for the North Indian INFIR cohort
    • 1:CAS:528:DC%2BC38XhsFWjtg%3D%3D 3236729 22180790 10.1371/journal.pntd. 0001327
    • Lockwood DN, Suneetha L, Sagili KD, Chaduvula MV, Mohammed I, van Brakel W, et al. Cytokine and protein markers of leprosy reactions in skin and nerves: baseline results for the North Indian INFIR cohort. PLoS Negl Trop Dis. 2011;5(12):e1327.
    • (2011) PLoS Negl Trop Dis , vol.5 , Issue.12 , pp. 1327
    • Lockwood, D.N.1    Suneetha, L.2    Sagili, K.D.3    Chaduvula, M.V.4    Mohammed, I.5    Van Brakel, W.6
  • 6
    • 84876006539 scopus 로고    scopus 로고
    • Diagnosis and treatment of leprosy reactions in integrated services - The patients' perspective in Nepal
    • 3591330 23505585 10.1371/journal.pntd.0002089
    • Raffe SF, Thapa M, Khadge S, Tamang K, Hagge D, Lockwood DN. Diagnosis and treatment of leprosy reactions in integrated services - the patients' perspective in Nepal. PLoS Negl Trop Dis. 2013;7(3):e2089.
    • (2013) PLoS Negl Trop Dis , vol.7 , Issue.3 , pp. 2089
    • Raffe, S.F.1    Thapa, M.2    Khadge, S.3    Tamang, K.4    Hagge, D.5    Lockwood, D.N.6
  • 7
    • 19844378175 scopus 로고    scopus 로고
    • The INFIR Cohort Study: Investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in north India
    • 15881033
    • van Brakel WH, Nicholls PG, Das L, Barkataki P, Suneetha SK, Jadhav RS, et al. The INFIR Cohort Study: investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in north India. Lepr Rev. 2005;76(1):14-34.
    • (2005) Lepr Rev , vol.76 , Issue.1 , pp. 14-34
    • Van Brakel, W.H.1    Nicholls, P.G.2    Das, L.3    Barkataki, P.4    Suneetha, S.K.5    Jadhav, R.S.6
  • 8
    • 0025759321 scopus 로고
    • Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states
    • 1:STN:280:DyaK3M7pvFCgtw%3D%3D 1535359 2015700
    • Sarno EN, Grau GE, Vieira LM, Nery JA. Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states. Clin Exp Immunol. 1991;84(1):103-8.
    • (1991) Clin Exp Immunol , vol.84 , Issue.1 , pp. 103-108
    • Sarno, E.N.1    Grau, G.E.2    Vieira, L.M.3    Nery, J.A.4
  • 9
    • 67649205754 scopus 로고    scopus 로고
    • Potential plasma markers of Type 1 and Type 2 leprosy reactions: A preliminary report
    • 2696458 19473542 10.1186/1471-2334-9-75
    • Stefani MM, Guerra JG, Sousa AL, Costa MB, Oliveira ML, Martelli CT, et al. Potential plasma markers of Type 1 and Type 2 leprosy reactions: a preliminary report. BMC Infect Dis. 2009;9:75.
    • (2009) BMC Infect Dis , vol.9 , pp. 75
    • Stefani, M.M.1    Guerra, J.G.2    Sousa, A.L.3    Costa, M.B.4    Oliveira, M.L.5    Martelli, C.T.6
  • 10
    • 79957991338 scopus 로고    scopus 로고
    • Increased CXC ligand 10 levels and gene expression in type 1 leprosy reactions
    • 1:CAS:528:DC%2BC3MXnsFOjt70%3D 3122607 21508169 10.1128/CVI.00042-11
    • Scollard DM, Chaduvula MV, Martinez A, Fowlkes N, Nath I, Stryjewska BM, et al. Increased CXC ligand 10 levels and gene expression in type 1 leprosy reactions. Clin Vaccine Immunol. 2011;18(6):947-53.
    • (2011) Clin Vaccine Immunol , vol.18 , Issue.6 , pp. 947-953
    • Scollard, D.M.1    Chaduvula, M.V.2    Martinez, A.3    Fowlkes, N.4    Nath, I.5    Stryjewska, B.M.6
  • 11
    • 0035122113 scopus 로고    scopus 로고
    • Sequential erythema nodosum leprosum and reversal reaction with similar lesional cytokine mRNA patterns in a borderline leprosy patient
    • 1:STN:280:DC%2BD3M3gsVWitA%3D%3D 11167702 10.1046/j.1365-2133.2001.03970. x
    • Moraes MO, Sampaio EP, Nery JA, Saraiva BC, Alvarenga FB, Sarno EN. Sequential erythema nodosum leprosum and reversal reaction with similar lesional cytokine mRNA patterns in a borderline leprosy patient. Br J Dermatol. 2001;144(1):175-81.
    • (2001) Br J Dermatol , vol.144 , Issue.1 , pp. 175-181
    • Moraes, M.O.1    Sampaio, E.P.2    Nery, J.A.3    Saraiva, B.C.4    Alvarenga, F.B.5    Sarno, E.N.6
  • 12
    • 84876838070 scopus 로고    scopus 로고
    • Challenges in immunodiagnostic tests for leprosy
    • 1:CAS:528:DC%2BC3sXms1Gmtb8%3D 23537134 10.1517/17530059.2013.786039
    • Geluk A. Challenges in immunodiagnostic tests for leprosy. Expert Opin Med Diagn. 2013;7(3):265-74.
    • (2013) Expert Opin Med Diagn , vol.7 , Issue.3 , pp. 265-274
    • Geluk, A.1
  • 13
    • 36749016808 scopus 로고    scopus 로고
    • Utility of measuring serum levels of anti-PGL-I antibody, neopterin and C-reactive protein in monitoring leprosy patients during multi-drug treatment and reactions
    • 1:CAS:528:DC%2BD1cXhtlSiu7w%3D 18076551 10.1111/j.1365-3156.2007.01951.x
    • Silva EA, Iyer A, Ura S, Lauris JR, Naafs B, Das PK, et al. Utility of measuring serum levels of anti-PGL-I antibody, neopterin and C-reactive protein in monitoring leprosy patients during multi-drug treatment and reactions. Trop Med Int Health. 2007;12(12):1450-8.
    • (2007) Trop Med Int Health , vol.12 , Issue.12 , pp. 1450-1458
    • Silva, E.A.1    Iyer, A.2    Ura, S.3    Lauris, J.R.4    Naafs, B.5    Das, P.K.6
  • 14
    • 35348947980 scopus 로고    scopus 로고
    • Serum levels of interferon-gamma, tumour necrosis factor-alpha, soluble interleukin-6R and soluble cell activation markers for monitoring response to treatment of leprosy reactions
    • 1:CAS:528:DC%2BD2sXhtl2gur7N 2219358 17937676 10.1111/j.1365-2249.2007. 03485.x
    • Iyer A, Hatta M, Usman R, Luiten S, Oskam L, Faber W, et al. Serum levels of interferon-gamma, tumour necrosis factor-alpha, soluble interleukin-6R and soluble cell activation markers for monitoring response to treatment of leprosy reactions. Clin Exp Immunol. 2007;150(2):210-6.
    • (2007) Clin Exp Immunol , vol.150 , Issue.2 , pp. 210-216
    • Iyer, A.1    Hatta, M.2    Usman, R.3    Luiten, S.4    Oskam, L.5    Faber, W.6
  • 15
    • 84861122390 scopus 로고    scopus 로고
    • New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy
    • 1:CAS:528:DC%2BC38XmsVGmurc%3D 3345093 22504648 10.4049/jimmunol.1103452
    • Geluk A, Bobosha K, van der Ploeg-van Schip JJ, Spencer JS, Banu S, Martins SB, et al. New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy. J Immunol. 2012;188(10):4782-91.
    • (2012) J Immunol , vol.188 , Issue.10 , pp. 4782-4791
    • Geluk, A.1    Bobosha, K.2    Van Der Ploeg-Van Schip, J.J.3    Spencer, J.S.4    Banu, S.5    Martins, S.B.6
  • 16
    • 84855968010 scopus 로고    scopus 로고
    • Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay
    • 1:CAS:528:DC%2BC38XhtV2lt7o%3D 21956656 10.1038/gene.2011.64
    • Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, Jacobsen M, et al. Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay. Genes Immun. 2012;13(1):71-82.
    • (2012) Genes Immun , vol.13 , Issue.1 , pp. 71-82
    • Joosten, S.A.1    Goeman, J.J.2    Sutherland, J.S.3    Opmeer, L.4    De Boer, K.G.5    Jacobsen, M.6
  • 17
    • 84873548317 scopus 로고    scopus 로고
    • An unbiased genome-wide mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection
    • 1:CAS:528:DC%2BC3sXhvFGmsbo%3D 23319735 10.4049/jimmunol.1201593
    • Commandeur S, van Meijgaarden KE, Prins C, Pichugin AV, Dijkman K, van den Eeden SJ, et al. An unbiased genome-wide mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection. J Immunol. 2013;190(4):1659-71.
    • (2013) J Immunol , vol.190 , Issue.4 , pp. 1659-1671
    • Commandeur, S.1    Van Meijgaarden, K.E.2    Prins, C.3    Pichugin, A.V.4    Dijkman, K.5    Van Den Eeden, S.J.6
  • 18
    • 84865620173 scopus 로고    scopus 로고
    • HLA-E expression in cervical adenocarcinomas: Association with improved long-term survival
    • 1:CAS:528:DC%2BC38XhvVSiu7fK 3480912 22947189 10.1186/1479-5876-10-184
    • Spaans VM, Peters AA, Fleuren GJ, Jordanova ES. HLA-E expression in cervical adenocarcinomas: association with improved long-term survival. J Transl Med. 2012;10:184.
    • (2012) J Transl Med , vol.10 , pp. 184
    • Spaans, V.M.1    Peters, A.A.2    Fleuren, G.J.3    Jordanova, E.S.4
  • 19
    • 33846818409 scopus 로고    scopus 로고
    • Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment
    • 1:CAS:528:DC%2BD2sXhs1ahs7s%3D 1828524 17145950 10.1128/IAI.00602-06
    • Sahiratmadja E, Alisjahbana B, de Boer T, Adnan I, Maya A, Danusantoso H, et al. Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment. Infect Immun. 2007;75(2):820-9.
    • (2007) Infect Immun , vol.75 , Issue.2 , pp. 820-829
    • Sahiratmadja, E.1    Alisjahbana, B.2    De Boer, T.3    Adnan, I.4    Maya, A.5    Danusantoso, H.6
  • 20
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • 1:CAS:528:DC%2BC3cXhtVyks7bN 3492754 20725040 10.1038/nature09247
    • Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, Oni T, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature. 2010;466(7309):973-7.
    • (2010) Nature , vol.466 , Issue.7309 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.5    Oni, T.6
  • 21
    • 12144288237 scopus 로고    scopus 로고
    • Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
    • 1:CAS:528:DC%2BD2cXjtFKis70%3D 384786 15070757 10.1073/pnas.0400983101
    • Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, et al. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. Proc Natl Acad Sci U S A. 2004;101(13):4560-5.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.13 , pp. 4560-4565
    • Verreck, F.A.1    De Boer, T.2    Langenberg, D.M.3    Hoeve, M.A.4    Kramer, M.5    Vaisberg, E.6
  • 22
    • 49649093608 scopus 로고    scopus 로고
    • Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1
    • 1:CAS:528:DC%2BD1cXos12ntrc%3D 18641362
    • Savage ND, de Boer T, Walburg KV, Joosten SA, van Meijgaarden K, Geluk A, et al. Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1. J Immunol. 2008;181(3):2220-6.
    • (2008) J Immunol , vol.181 , Issue.3 , pp. 2220-2226
    • Savage, N.D.1    De Boer, T.2    Walburg, K.V.3    Joosten, S.A.4    Van Meijgaarden, K.5    Geluk, A.6
  • 23
    • 34249944837 scopus 로고    scopus 로고
    • Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4
    • 1:CAS:528:DC%2BD2sXmtFCiurk%3D 1876566 17483450 10.1073/pnas.0702257104
    • Joosten SA, van Meijgaarden KE, Savage ND, de Boer T, Triebel F, van der Wal A, et al. Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4. Proc Natl Acad Sci U S A. 2007;104(19):8029-34.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.19 , pp. 8029-8034
    • Joosten, S.A.1    Van Meijgaarden, K.E.2    Savage, N.D.3    De Boer, T.4    Triebel, F.5    Van Der Wal, A.6
  • 24
    • 34247643786 scopus 로고    scopus 로고
    • The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: Multiple pathways on the road
    • 1:CAS:528:DC%2BD2sXkvFCnsrY%3D 17311282 10.1002/jcp.21001
    • Zhang L, Zhao Y. The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. J Cell Physiol. 2007;211(3):590-7.
    • (2007) J Cell Physiol , vol.211 , Issue.3 , pp. 590-597
    • Zhang, L.1    Zhao, Y.2
  • 25
    • 84870732395 scopus 로고    scopus 로고
    • Human Beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions
    • 1:CAS:528:DC%2BC38XhslWjsr3J 3486878 23133681 10.1371/journal.pntd. 0001869
    • Cogen AL, Walker SL, Roberts CH, Hagge DA, Neupane KD, Khadge S, et al. Human Beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions. PLoS Negl Trop Dis. 2012;6(11):e1869.
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.11 , pp. 1869
    • Cogen, A.L.1    Walker, S.L.2    Roberts, C.H.3    Hagge, D.A.4    Neupane, K.D.5    Khadge, S.6
  • 26
    • 84875425732 scopus 로고    scopus 로고
    • Type i interferon suppresses type II interferon-triggered human anti-mycobacterial responses
    • 1:CAS:528:DC%2BC3sXktF2qsrg%3D 23449998 10.1126/science.1233665
    • Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013;339(6126):1448-53.
    • (2013) Science , vol.339 , Issue.6126 , pp. 1448-1453
    • Teles, R.M.1    Graeber, T.G.2    Krutzik, S.R.3    Montoya, D.4    Schenk, M.5    Lee, D.J.6
  • 27
    • 84865792720 scopus 로고    scopus 로고
    • New pathways of protective and pathological host defense to mycobacteria
    • 1:CAS:528:DC%2BC38XhtVSgtb7I 22784857 10.1016/j.tim.2012.06.002
    • Ottenhoff TH. New pathways of protective and pathological host defense to mycobacteria. Trends Microbiol. 2012;20(9):419-28.
    • (2012) Trends Microbiol , vol.20 , Issue.9 , pp. 419-428
    • Ottenhoff, T.H.1
  • 28
    • 74049127960 scopus 로고    scopus 로고
    • Genomewide association study of leprosy
    • 1:CAS:528:DC%2BC3cXjsFSmtg%3D%3D 20018961 10.1056/NEJMoa0903753
    • Zhang FR, Huang W, Chen SM, Sun LD, Liu H, Li Y, et al. Genomewide association study of leprosy. N Engl J Med. 2009;361(27):2609-18.
    • (2009) N Engl J Med , vol.361 , Issue.27 , pp. 2609-2618
    • Zhang, F.R.1    Huang, W.2    Chen, S.M.3    Sun, L.D.4    Liu, H.5    Li, Y.6
  • 29
    • 67649280552 scopus 로고    scopus 로고
    • Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: Preliminary report
    • 2696407 19445695 10.1186/1471-2466-9-21
    • Chegou NN, Black GF, Kidd M, van Helden PD, Walzl G. Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report. BMC Pulm Med. 2009;9:21.
    • (2009) BMC Pulm Med , vol.9 , pp. 21
    • Chegou, N.N.1    Black, G.F.2    Kidd, M.3    Van Helden, P.D.4    Walzl, G.5
  • 30
    • 70349745514 scopus 로고    scopus 로고
    • From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
    • 1:CAS:528:DC%2BD1MXht1Ogs73I 2757811 19805374 10.1073/pnas.0902869106
    • Friedman DJ, Kunzli BM, Rahim YI, Sevigny J, Berberat PO, Enjyoji K, et al. From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease. Proc Natl Acad Sci U S A. 2009;106(39):16788-93.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.39 , pp. 16788-16793
    • Friedman, D.J.1    Kunzli, B.M.2    Rahim, Y.I.3    Sevigny, J.4    Berberat, P.O.5    Enjyoji, K.6
  • 31
    • 84880000381 scopus 로고    scopus 로고
    • CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8 CD39 regulatory T cells
    • 1:CAS:528:DC%2BC3sXot1CgsLg%3D 23606272 10.1002/eji.201243286
    • Boer MC, van Meijgaarden KE, Bastid J, Ottenhoff TH, Joosten SA. CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8 CD39 regulatory T cells. Eur J Immunol. 2013;43(7):1925-32.
    • (2013) Eur J Immunol , vol.43 , Issue.7 , pp. 1925-1932
    • Boer, M.C.1    Van Meijgaarden, K.E.2    Bastid, J.3    Ottenhoff, T.H.4    Joosten, S.A.5
  • 32
    • 77954355483 scopus 로고    scopus 로고
    • Investigating the induction of vaccine-induced Th17 and regulatory T cells in healthy, Mycobacterium bovis BCG-immunized adults vaccinated with a new tuberculosis vaccine, MVA85A
    • 2897259 20484570 10.1128/CVI.00047-10
    • de Cassan SC, Pathan AA, Sander CR, Minassian A, Rowland R, Hill AV, et al. Investigating the induction of vaccine-induced Th17 and regulatory T cells in healthy, Mycobacterium bovis BCG-immunized adults vaccinated with a new tuberculosis vaccine, MVA85A. Clin Vaccine Immunol. 2010;17(7):1066-73.
    • (2010) Clin Vaccine Immunol , vol.17 , Issue.7 , pp. 1066-1073
    • De Cassan, S.C.1    Pathan, A.A.2    Sander, C.R.3    Minassian, A.4    Rowland, R.5    Hill, A.V.6
  • 33
    • 48949118047 scopus 로고    scopus 로고
    • Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction
    • 2330092 18461142 10.1371/journal.pntd.0000231
    • Misch EA, Macdonald M, Ranjit C, Sapkota BR, Wells RD, Siddiqui MR, et al. Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis. 2008;2(5):e231.
    • (2008) PLoS Negl Trop Dis , vol.2 , Issue.5 , pp. 231
    • Misch, E.A.1    Macdonald, M.2    Ranjit, C.3    Sapkota, B.R.4    Wells, R.D.5    Siddiqui, M.R.6
  • 34
    • 84867584238 scopus 로고    scopus 로고
    • Beneficial effects of sitostanol on the attenuated immune function in asthma patients: Results of an in vitro approach
    • 3473039 23091602 10.1371/journal.pone.0046895
    • Brull F, Mensink RP, Steinbusch MF, Husche C, Lutjohann D, Wesseling GJ, et al. Beneficial effects of sitostanol on the attenuated immune function in asthma patients: results of an in vitro approach. PLoS ONE. 2012;7(10):e46895.
    • (2012) PLoS ONE , vol.7 , Issue.10 , pp. 46895
    • Brull, F.1    Mensink, R.P.2    Steinbusch, M.F.3    Husche, C.4    Lutjohann, D.5    Wesseling, G.J.6
  • 35
    • 84867216518 scopus 로고    scopus 로고
    • Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability
    • 1:CAS:528:DC%2BC38XhtFClsLnI 3668644 22740122 10.1002/eji.201142317
    • Lee JH, Lydon JP, Kim CH. Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability. Eur J Immunol. 2012;42(10):2683-96.
    • (2012) Eur J Immunol , vol.42 , Issue.10 , pp. 2683-2696
    • Lee, J.H.1    Lydon, J.P.2    Kim, C.H.3
  • 36
    • 0035128680 scopus 로고    scopus 로고
    • T-cell release of granulysin contributes to host defense in leprosy
    • 1:CAS:528:DC%2BD3MXhtVygsLw%3D 11175847 10.1038/84620
    • Ochoa MT, Stenger S, Sieling PA, Thoma-Uszynski S, Sabet S, Cho S, et al. T-cell release of granulysin contributes to host defense in leprosy. Nat Med. 2001;7(2):174-9.
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 174-179
    • Ochoa, M.T.1    Stenger, S.2    Sieling, P.A.3    Thoma-Uszynski, S.4    Sabet, S.5    Cho, S.6
  • 37
    • 84856257184 scopus 로고    scopus 로고
    • Circulating levels of insulin-like growth factor-I (IGF-I) correlate with disease status in leprosy
    • 1:CAS:528:DC%2BC38XivVWit7g%3D 3266221 22166091 10.1186/1471-2334-11-339
    • Rodrigues LS, Hacker MA, Illarramendi X, Pinheiro MF, Nery JA, Sarno EN, et al. Circulating levels of insulin-like growth factor-I (IGF-I) correlate with disease status in leprosy. BMC Infect Dis. 2011;11:339.
    • (2011) BMC Infect Dis , vol.11 , pp. 339
    • Rodrigues, L.S.1    Hacker, M.A.2    Illarramendi, X.3    Pinheiro, M.F.4    Nery, J.A.5    Sarno, E.N.6
  • 38
    • 0035369084 scopus 로고    scopus 로고
    • Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta
    • 1:CAS:528:DC%2BD3MXktlSqtrw%3D 11389829 10.1016/S0092-8674(01)00363-4
    • Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, et al. Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta. Cell. 2001;105(5):587-97.
    • (2001) Cell , vol.105 , Issue.5 , pp. 587-597
    • Zhao, C.1    Takita, J.2    Tanaka, Y.3    Setou, M.4    Nakagawa, T.5    Takeda, S.6
  • 39
    • 0022591242 scopus 로고
    • Single-patient randomised clinical trial. Use in determining optimum treatment for patient with inflammation of Kock continent ileostomy reservoir
    • 1:STN:280:DyaL287ntlKgug%3D%3D 2870233 10.1016/S0140-6736(86)91112-8
    • McLeod RS, Taylor DW, Cohen Z, Cullen JB. Single-patient randomised clinical trial. Use in determining optimum treatment for patient with inflammation of Kock continent ileostomy reservoir. Lancet. 1986;1(8483):726-8.
    • (1986) Lancet , vol.1 , Issue.8483 , pp. 726-728
    • McLeod, R.S.1    Taylor, D.W.2    Cohen, Z.3    Cullen, J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.