Diagnostic accuracy of induced sputum LAM ELISA for tuberculosis diagnosis in sputum-scarce patients

International Journal of Tuberculosis and Lung Disease

Volumn 16, Issue 8, 2012, Pages 1108-1112

  Peter, J G ^a   Cashmore, T J ^a   Meldau, R ^a   Theron, G ^a   Van Zyl Smit, R ^a   Dheda, Keertan ^a,b,c  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Detection; ELISA; Infectious disease

Indexed keywords

LIPOARABINOMANNAN; PROTEIN;

ADULT; ARTICLE; BACTERIUM CULTURE; CELL COUNT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIQUID CULTURE; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MOUTH HYGIENE; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SOUTH AFRICA; SPUTUM ANALYSIS; SPUTUM SMEAR; STANDARD; URINALYSIS;

ADULT; BIOLOGICAL MARKERS; COINFECTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV INFECTIONS; HUMANS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PREDICTIVE VALUE OF TESTS; ROC CURVE; SENSITIVITY AND SPECIFICITY; SOUTH AFRICA; SPUTUM; TUBERCULOSIS, PULMONARY;

EID: 84863568592     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: 10.5588/ijtld.11.0614     Document Type: Article

References (16)

1. World Health Organization. Global tuberculosis control: surveillance, planning, financing. WHO report 2008. WHO/HTM/TB/2008.393. Geneva, Switzerland: WHO, 2008.
2. Getahun H, Harrington M, O'Brien R, Nunn P. Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes. Lancet 2007; 369: 2042-2049. (Pubitemid 46908825)
3. Boehme C C, Nabeta P, Hillemann D, et al. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 2010; 363: 1005-1015.
4. Mishra A K, Driessen N N, Appelmelk B J, Besra G S. Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction. FEMS Microbiol Rev 2011; 35: 1126-1157.
5. Tessema T A, Hamasur B, Bjun G, Svenson S, Bjorvatn B. Diagnostic evaluation of urinary lipoarabinomannan at an Ethiopian tuberculosis centre. Scand J Infect Dis 2001; 33: 279-284. (Pubitemid 32366653)
6. Peter J, Green C, Hoelscher M, Mwaba P, Zumla A, Dheda K. Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments. Curr Opin Pulm Med 2010; 16: 262-270.
7. Peter J G, Theron G, van Zyl-Smit R, et al. Diagnostic accuracy of a urine LAM strip-test for TB detection in HIV-infected hospitalized patients. Eur Respir J 2012; Feb 23. [epub ahead of print]
8. Tessema T A, Bjune G, Hamasur B, Svenson S, Syre H, Bjorvatn B. Circulating antibodies to lipoarabinomannan in relation to sputum microscopy, clinical features and urinary antilipoarabinomannan detection in pulmonary tuberculosis. Scand J Infect Dis 2002; 34: 97-103. (Pubitemid 34213369)
9. Sada E, Brennan P J, Herrera T, Torres M. Evaluation of lipoarabinomannan for the serological diagnosis of tuberculosis. J Clin Microbiol 1990; 28: 2587-2590.
10. Dheda K, van-Zyl Smit R N, Sechi L A, et al. Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting. PLoS One 2009; 4: e4689.
11. Patel V B, Bhigjee A I, Paruk H F, et al. Utility of a novel lipoarabinomannan assay for the diagnosis of tuberculous meningitis in a resource-poor high-HIV prevalence setting. Cerebrospinal Fluid Res 2009; 6: 13.
12. Theron G, Peter J, van Zyl-Smit R, et al. Evaluation of the Xpert® MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting. Am J Respir Crit Care Med 2011; 184: 132-140.
13. Cashmore T J, Peter J G, van Zyl-Smit R N, et al. Feasibility and diagnostic utility of antigen-specific interferon-gamma responses for rapid immunodiagnosis of tuberculosis using induced sputum. PLoS One 2010; 5: e10389.
14. Bartlett R C. Medical microbiology: quality, cost, and clinical relevance. New York, NY, USA: John Wiley & Sons, 1974.
15. Dheda K, Davids V, Lenders L, et al. Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples. PLoS One 2010; 5: e9848.
16. Mall A S, McLeod H A, Hickman R, Kahn D, Dent D M. Fragmentation pattern of mucins in normal and diseased gastric mucosae: a glycoprotein fractionates with gastric mucins purifi ed from mucosal scrapings of cancer and peptic ulcer patients. Digestion 1999; 60: 216-226. (Pubitemid 29221888)