Perturbed CD8+ T cell immunity across universal influenza epitopes in the elderly

Journal of Leukocyte Biology

Volumn 103, Issue 2, 2018, Pages 321-339

  Nguyen, Thi H O ^a   Sant, Sneha ^a   Bird, Nicola L ^a   Grant, Emma J ^a,b,c   Clemens, E Bridie ^a   Koutsakos, Marios ^a   Valkenburg, Sophie A ^a,d   Gras, Stephanie ^c   Lappas, Martha ^a,e   Jaworowski, Anthony ^f,g   Crowe, Jane ^h   Loh, Liyen ^a   Kedzierska, Katherine ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e MERCY HOSPITAL FOR WOMEN   (Australia)

^f ALFRED HOSPITAL   (Australia)

^g BURNET INSTITUTE   (Australia)

^h Deepdene Surgery   (Australia)

Author keywords

aging; CD8+ T cells; TCR repertoire; transcription factors; ZAP 70

Indexed keywords

EPITOPE; HLA A2 ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EOMES; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; AGING; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; GERIATRIC PATIENT; HUMAN; HUMAN CELL; INFLUENZA; LYMPHOCYTE COUNT; MEMORY T LYMPHOCYTE; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; VERY ELDERLY; AGE; BLOOD; COHORT ANALYSIS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INFLUENZA A VIRUS; METABOLISM; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGE FACTORS; AGED; AGING; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS; INFLUENZA, HUMAN; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS;

EID: 85040998104     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.5MA0517-207R     Document Type: Article

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