Preexisting CD8+ T-cell immunity to the H7N9 influenza a virus varies across ethnicities

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 3, 2014, Pages 1049-1054

  Quiñones Parra, Sergio ^a   Grant, Emma ^a   Loh, Liyen ^a   Nguyen, Thi H O ^a,b   Campbell, Kristy Anne ^b   Tong, Steven Y C ^c   Miller, Adrian ^d   Doherty, Peter C ^a,e   Vijaykrishna, Dhanasekaran ^f   Rossjohn, Jamie ^b,g   Gras, Stephanie ^b   Kedzierska, Katherine ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c CHARLES DARWIN UNIVERSITY   (Australia)

^d GRIFFITH UNIVERSITY   (Australia)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

CD8 T cells; HLA types

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; MATRIX PROTEIN; NUCLEOPROTEIN; VIRUS NUCLEOPROTEIN;

ALLELE; ARTICLE; AUSTRALIA; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS REACTION; CYTOTOXIC T LYMPHOCYTE; ETHNIC DIFFERENCE; HLA SYSTEM; HUMAN; HUMAN CELL; INDIGENOUS PEOPLE; INFLUENZA VIRUS A H7N9; MEMORY T LYMPHOCYTE; NORMAL HUMAN; PEPTIDE MAPPING; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; UNITED STATES; VIRUS STRAIN;

CD8 T CELLS; HLA TYPES;

AUSTRALIA; CD8-POSITIVE T-LYMPHOCYTES; CROSS REACTIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES, T-LYMPHOCYTE; ETHNIC GROUPS; HLA ANTIGENS; HLA-A ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA VACCINES; INFLUENZA, HUMAN; LEUKOCYTES, MONONUCLEAR; LIKELIHOOD FUNCTIONS; MUTATION; PEPTIDES;

EID: 84892914586     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1322229111     Document Type: Article

References (32)

1. WHO (2013) Avian Influenza A (H7N9) virus. Available at www.who.int/influenza/human-animal-interface/influenza-h7n9/10u- ReportWebH7N9Number.pdf. Accessed October, 2013.
2. Chen Y, et al. (2013) Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: Clinical analysis and characterisation of viral genome. Lancet 381(9881):1916-1925.
3. Li Q, et al. (2013) Preliminary Report: Epidemiology of the Avian Influenza A (H7N9) Outbreak in China. N Engl J Med, 10.1056/NEJMoa1304617.
4. Zhu H, et al. (2013) Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science 341(6142):183-186.
5. Uyeki TM, Cox NJ (2013) Global concerns regarding novel influenza A (H7N9) virus infections. N Engl J Med 368(20):1862-1864.
6. Bender BS, Croghan T, Zhang L, Small PA, Jr. (1992) Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. J Exp Med 175(4):1143-1145.
7. McMichael AJ, Gotch FM, Noble GR, Beare PA (1983) Cytotoxic T-cell immunity to influenza. N Engl J Med 309(1):13-17.
8. Epstein SL (2006) Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: An experiment of nature. J Infect Dis 193(1):49-53.
9. Sridhar S, et al. (2013) Cellular immune correlates of protection against symptomatic pandemic influenza. Nat Med 19(10):1305-1312.
10. La Ruche G, et al. (2009) The 2009 pandemic H1N1 influenza and indigenous populations of the Americas and the Pacific. Eur Surveillance Bull 14(42):1-6.
11. Grant E, et al. (2013) Nucleoprotein of influenza A virus is a major target of immunodominant CD8+ T-cell responses. Immunol Cell Biol 91(2):184-194.
12. Lee LY, et al. (2008) Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. J Clin Invest 118(10):3478-3490.
13. Voeten JT, et al. (2000) Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes. J Virol 74(15):6800-6807.
14. Wahl A, et al. (2009) HLA class I molecules consistently present internal influenza epitopes. Proc Natl Acad Sci USA 106(2):540-545.
15. Boon AC, et al. (2004) Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes. J Immunol 172(4):2453-2460.
16. Gras S, et al. (2010) Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc Natl Acad Sci USA 107(28):12599-12604.
17. Theodossis A, et al. (2010) Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition. Proc Natl Acad Sci USA 107(12):5534-5539.
18. Goulder PJ, Walker BD (2012) HIV and HLA class I: An evolving relationship. Immunity 37(3):426-440.
19. Hertz T, et al. (2013) HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proc Natl Acad Sci USA 110(33):13492-13497.
20. Ahmed R, Oldstone MB, Palese P (2007) Protective immunity and susceptibility to infectious diseases: Lessons from the 1918 influenza pandemic. Nat Immunol 8(11):1188-1193.
21. Briscoe G (1996) Disease health and healing-Aspects of indigenous health in WA & Queensland, 1900-1940 (Australian National University, Canberra, ACT, Australia). PhD thesis.
22. Flint SM, et al. (2010) Disproportionate impact of pandemic (H1N1) 2009 influenza on Indigenous people in the Top End of Australia's Northern Territory. Med J Aust 192(10):617-622.
23. Trauer JM, Laurie KL, McDonnell J, Kelso A, Markey PG (2011) Differential effects of pandemic (H1N1) 2009 on remote and indigenous groups, Northern Territory, Australia, 2009. Emerg Infect Dis 17(9):1615-1623.
24. Lam TT, et al. (2013) The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature 502(7470):241-244.
25. Valkenburg SA, et al. (2013) Acute emergence and reversion of influenza A virus quasispecies within CD8 (+) T cell antigenic peptides. Nat Commun 4:2663.
26. Greenbaum JA, et al. (2009) Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population. Proc Natl Acad Sci USA 106(48):20365-20370.
27. Gao HN, et al. (2013) Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 368(24):2277-2285.
28. De Lano WL (2002) The PyMOL molecular graphics system. Available at www.pymol.org. Accessed August, 2013.
29. Chen AT, et al. (2012) Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope. PLoS Pathog 8(4):e1002633.
30. Stamatakis A (2006) RAxML-VI-HPC: Maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 22(21):2688-2690.
31. Marsh S G E, et al. (2000) The HLA Factsbook (Academic Press, San Diego).
32. CBI () DbMHC, Diversity anthropology component. Available at www.ncbi.nlm.nih. gov/gv/mhc/ihwg.cgi?cmd=page&page=AnthroMain. Accessed September, 2013.