Early priming minimizes the age-related immune compromise of CD8+ T cell diversity and function

PLoS Pathogens

Volumn 8, Issue 2, 2012, Pages

  Valkenburg, Sophie A ^a   Venturi, Vanessa ^b   Dang, Thurston H Y ^b   Bird, Nicola L ^a   Doherty, Peter C ^a,b   Turner, Stephen J ^a   Davenport, Miles P ^c   Kedzierska, Katherine ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; EPITOPE; LYMPHOCYTE ANTIGEN RECEPTOR;

AGE; AGING; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CROSS PRESENTATION; EARLY INTERVENTION; FEMALE; IMMUNE DEFICIENCY; INFLUENZA VACCINATION; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; T LYMPHOCYTE SUBPOPULATION; ANIMAL; ANTIGEN PRESENTATION; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PRE T LYMPHOCYTE; VALIDATION STUDY;

ANIMALIA; INFLUENZA A VIRUS; MUS;

AGE FACTORS; AGING; ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; FEMALE; IMMUNOLOGIC MEMORY; MICE; MICE, INBRED C57BL; PRECURSOR CELLS, T-LYMPHOID; RECEPTORS, ANTIGEN, T-CELL; VALIDATION STUDIES AS TOPIC;

EID: 84860893942     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002544     Document Type: Article

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