Evolution of the antigen-specific CD8+ TCR repertoire across the life span: Evidence for clonal homogenization of the old TCR repertoire

Journal of Immunology

Volumn 186, Issue 4, 2011, Pages 2056-2064

  Rudd, Brian D ^a,b   Venturi, Vanessa ^c   Davenport, Miles P ^c   Nikolich Žugich, Janko ^a,b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GLYCOPROTEIN B; HERPES SIMPLEX VIRUS GLYCOPROTEIN B 8P; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AGING; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL SELECTION; CONTROLLED STUDY; EVOLUTION; FLOW CYTOMETRY; LIFESPAN; MOLECULAR CLONING; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VACCINIA VIRUS;

ANIMALS; ANIMALS, NEWBORN; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CLONE CELLS; EPITOPES, T-LYMPHOCYTE; EVOLUTION, MOLECULAR; HERPESVIRUS 1, HUMAN; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN VARIABLE REGION; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 79951821255     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003013     Document Type: Article

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